A recent study published in JAMA Network Open reveals that nearly half of long-term antidepressant users can successfully taper off their medication with the help of general practitioner support and internet or telephone helplines. The study found lower rates of depression, fewer withdrawal symptoms, and improved mental wellbeing among...
SourceUniversity of Southampton·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateJun 26, 2024
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
A prospective study found that medication abortion via no-test telehealth and mailing of medications was comparable in effectiveness to in-person care with ultrasonography. The research also revealed low adverse event rates across all groups.
The Pfizer-BioNTech vaccine demonstrated strong protection against a range of COVID-19 outcomes, including hospital admission. Annual updates to the vaccine are recommended due to waning immunity from older versions.
SourceJAMA Network·JournalJAMA Internal Medicine·DateJun 24, 2024
A randomized clinical trial found that an intermittent fasting plan consisting of two nonconsecutive fasting days and five days of meal replacement diet improved glycemic outcomes and weight loss in the short term compared to metformin or empagliflozin. The study suggests a promising initial intervention for type 2 diabetes management.
SourceJAMA Network·JournalJAMA Network Open·DateJun 21, 2024
Scientists are conducting a clinical trial to explore the use of anti-retroviral medications Ritonavir and Lopinavir as a potential treatment for brain tumors in patients with Neurofibromatosis 2. The study aims to determine if these drugs can help reduce tumor growth and survival in NF2 patients.
SourceUniversity of Plymouth·TypeRandomized controlled/clinical trial·DateJun 21, 2024
A study of 450 community outpatient mental health facilities found that approximately one-third offered medications for opioid use disorder. The availability of these medications highlights the need for further research on uptake and effective referral models.
SourceJAMA Network·JournalJAMA Network Open·DateJun 18, 2024
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A recent study has identified over 300 distinct types of bacteria in Roman Baths water, including those with antibiotic-producing capabilities. These microorganisms show promise as a potential source of novel natural products to combat antibiotic resistance.
SourceUniversity of Plymouth·JournalThe Microbe·TypeExperimental study·DateMay 31, 2024
A study published in Andrology found that testosterone therapy significantly improves body composition in transgender men, with no long-term side effects. Researchers also discovered that higher doses of testosterone may lead to faster results.
SourceOkayama University·JournalAndrology·TypeObservational study·DateMay 30, 2024
A study found that pharmaceuticals like metoprolol and atenolol, as well as illicit drugs such as cocaine and methamphetamine, were present in over 60% of water samples from Hudson and East Rivers. Enterococci bacteria and rainfall also contributed to drug presence, highlighting the need for improved water management systems
SourceWiley·JournalEnvironmental Toxicology and Chemistry·DateMay 29, 2024
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A phase 3 trial found that pamrevlumab did not significantly improve lung function in patients with idiopathic pulmonary fibrosis. The study's results underscore the need for effective treatments to slow disease progression and improve patient outcomes.
A new study finds mail-order pharmacy dispensing of mifepristone for medication abortion is effective, acceptable to patients, and feasible. This care model can improve access to medication abortion services and reduce the need for in-person screening.
SourceJAMA Network·JournalJAMA Internal Medicine·DateMay 13, 2024
A secondary analysis of a randomized clinical trial found that home blood pressure self-monitoring plus medication self-titration reduces BP in the longer term without increasing healthcare use or adverse events. This simple, inexpensive intervention has potential to improve long-term hypertension control in routine clinical practice.
SourceJAMA Network·JournalJAMA Network Open·DateMay 10, 2024
A telehealth program created by Project ECHO has been found to reduce reliance on opioids in pain management. The program connects primary care providers with experts via videoconferencing, leading to lower rates of opioid prescribing and greater adherence to evidence-based recommendations.
SourceUniversity of Missouri-Columbia·JournalJournal of Opioid Management·DateMay 7, 2024
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Black and Hispanic patients with atrial fibrillation were less likely to initiate direct oral anticoagulants at study onset, but these disparities narrowed over time. The study highlights the need to address unequal access to novel therapies for Black and Hispanic populations.
SourceJAMA Network·JournalJAMA Network Open·DateMay 6, 2024
A recent study published in JAMA Network Open found that understaffed nursing homes in disadvantaged neighborhoods are more likely to overmedicate residents with antipsychotics. The researchers suggest that increasing staffing levels could help reduce the use of these medications and address the root causes of behavioral issues.
SourceNew York University·JournalJAMA Network Open·DateApr 24, 2024
Researchers deciphered the molecular structure of bulevirtide in complex with HBV/HDV receptor NTCP, revealing a unique 'plug' that inhibits virus entry. The study also sheds light on evolutionary adaptation of HBVs to host species and provides insights for developing smaller, more effective active agents.
SourceGerman Center for Infection Research·JournalNature Communications·TypeExperimental study·DateApr 10, 2024
A new statistical-modeling workflow can quickly identify molecular structures of products formed by chemical reactions, accelerating drug discovery and synthetic chemistry. The workflow also enables the analysis of unpurified reaction mixtures, reducing time spent on purification and characterization.
SourceDOE/Lawrence Berkeley National Laboratory·JournalJournal of Chemical Information and Modeling·TypeData/statistical analysis·DateApr 8, 2024
The COVID-19 pandemic exacerbated pre-existing supply chain issues, leading to increased drug shortages in the US. Clinically valuable drugs at greatest shortage risk need prioritization to protect future supplies.
SourceJAMA Network·JournalJAMA Network Open·DateApr 5, 2024
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers develop innovative treatment to alleviate deleterious effects of hyperkalemia, a disease affecting 350 million people worldwide. The new mineral-based therapy uses ion transfer to flush excess potassium from the body, offering a safer alternative to existing treatments.
SourceNatural History Museum of Los Angeles County·JournalPLOS ONE·TypeExperimental study·DateMar 26, 2024
Researchers found that statins altered macrophage response and suppressed inflammatory response in periodontal disease. The study suggests statins could improve gum health and reduce heart disease risk.
SourceAmerican Society for Biochemistry and Molecular Biology·DateMar 25, 2024
After the Dobbs v Jackson Women’s Health Organization decision, a substantial number of abortion seekers accessed services. Provision of medications for self-managed abortions increased in the six months following the decision, indicating growing access to abortion services despite state-level bans and restrictions.
Researchers at Xi'an Jiaotong-Liverpool University developed a new method that enables the efficient production of cysteine-rich peptides and microproteins in their naturally folded 3D structure. The approach uses organic solvents to mimic nature's oxidative folding process, resulting in speeds of over 100,000 times faster than aqueous...
SourceXi'an Jiaotong-Liverpool University·JournalAngewandte Chemie·TypeExperimental study·DateMar 21, 2024
Researchers have made a breakthrough in developing genetic treatments for hereditary conditions like cystic fibrosis and inherited vision loss. They created a new type of lipid nanoparticle, called Thio-lipids, that can deliver therapeutic payloads to the lungs and retina.
SourceOregon State University·JournalProceedings of the National Academy of Sciences·DateMar 4, 2024
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
After 7 to 12 years of follow-up, bariatric surgery outperformed medical/lifestyle intervention in achieving superior glycemic control with reduced medication use and higher rates of diabetes remission. Individuals who underwent bariatric surgery had better long-term management of their type 2 diabetes.
Researchers have developed a new class of antibiotics that can overcome drug-resistant bacteria by targeting the physical and functional integrity of the bacterial cell wall. This could be a game-changer in treating infections, particularly those caused by resistant strains.
SourceUniversity of California - Santa Barbara·JournalScience Translational Medicine·DateFeb 21, 2024
A new study has found that heavy alcohol use and illicit opioid use are linked to a higher risk of falls and fractures among people living with HIV. The study suggests the need for targeted clinical screening and interventions to prevent falls and related injuries, particularly among populations already at risk.
SourceBoston University School of Public Health·JournalJAIDS Journal of Acquired Immune Deficiency Syndromes·TypeObservational study·DateFeb 21, 2024
A randomized clinical trial of 1,680 patients with acute ischemic stroke due to large-vessel occlusion found no significant improvement in disability with adjunctive methylprednisolone. The study suggests that methylprednisolone may not be effective as an adjunct therapy after endovascular thrombectomy for this patient population.
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A new study found that phenylephrine is the most popular nasal decongestant despite lack of evidence supporting its effectiveness. Removal from the market could disrupt supply chains and require significant investment in infrastructure for over-the-counter drug review.
SourceUniversity of Pittsburgh·JournalJAMA·TypeData/statistical analysis·DateFeb 8, 2024
Despite a lack of clinical efficacy evidence, phenylephrine remained the most common oral decongestant in the US from 2012-2021, with hundreds of millions of units sold annually. Most phenylephrine products were co-formulated with antihistamines or antitussives, providing symptom relief for cough and cold symptoms.
A randomized clinical trial of 1,015 participants found that apixaban did not significantly reduce recurrent stroke risk compared to aspirin in patients with cryptogenic stroke and atrial cardiopathy. The study suggests that alternative treatments may be more effective for preventing stroke recurrence in these patients.
A population-based study in Germany reveals almost 2 in 1,000 girls and women of childbearing age are prescribed isotretinoin, a medication linked to fetal defects. The study found a significant increase in isotretinoin-exposed pregnancies, highlighting the need for better monitoring and guidance.
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A special Journal of Intensive Medicine issue explores the latest research findings on ICU infections, prevention strategies, and innovative approaches to sepsis management. The studies shed light on key challenges and advancements in critical care, highlighting the need for personalized treatment methods.
SourceCactus Communications·JournalJournal of Intensive Medicine·TypeSystematic review·DateJan 12, 2024
A meta-analysis of 90 studies found that adolescents use nonprescription weight-loss products excessively, with girls being more affected. The study highlights the need for interventions to reduce this behavior and mitigate potential long-term health consequences.
SourceJAMA Network·JournalJAMA Network Open·DateJan 10, 2024
A nationwide case-time-control study found an association between benzodiazepine use during pregnancy and an increased risk of miscarriage. The results suggest that healthcare professionals should carefully weigh the benefits and risks of using benzodiazepines to treat psychiatric and sleep disorders in pregnant women.
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A recent study found that doxycycline prophylaxis did not prevent bacterial sexually transmitted infections (STIs) among cisgender women, despite being prescribed to 18% of participants. The study also revealed high rates of antibiotic-resistant gonorrhea, which may be due to low adherence and limited treatment options.
SourceHennepin Healthcare Research Institute·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateDec 21, 2023
A recent review of opioid medicines for cancer pain found surprisingly large gaps in evidence regarding their true benefits. Non-steroidal anti-inflammatory drugs (NSAIDs) may be at least as effective as some opioids for background cancer pain, offering potential alternatives to reduce dependence and waning analgesia over time.
SourceUniversity of Sydney·JournalCA A Cancer Journal for Clinicians·TypeSystematic review·DateDec 18, 2023
Klick Applied Sciences unveils LOVENet, an AI framework that rapidly identifies new therapeutic indications for existing drugs. The algorithm integrates large language model and structured knowledge graph technology to offer a fresh perspective on new potential applications.
SourceKlick Applied Sciences·TypeComputational simulation/modeling·DateDec 15, 2023
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A new study by NYU Langone Health found that patients from lower socioeconomic areas were less likely to fill their heart-failure medications, highlighting the importance of neighborhood-level interventions to improve access to lifesaving drugs. The research team plans to explore additional barriers, such as cost and language barriers,...
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalJAMA Network Open·DateDec 14, 2023
Patients with lower socioeconomic status in their neighborhoods have a higher risk of nonadherence to guideline-directed medical therapy for heart failure. Neighborhood-level socioeconomic factors play a significant role in shaping healthcare outcomes.
SourceJAMA Network·JournalJAMA Network Open·DateDec 14, 2023
A study by UNICAMP researchers found high concentrations of contaminants in the Piracicaba, Capivari and Jundiaí River Basin, including PFAS compounds, pesticides, and industrial chemicals. The study highlights the severity of pollution in the region, which supplies water for drinking, irrigation, and industry.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalChemosphere·DateNov 30, 2023
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A study of 278,000 individuals in Sweden found that longer cumulative duration of ADHD medication use was associated with an increased risk of hypertension and arterial disease. Clinicians should regularly monitor cardiovascular signs and symptoms during long-term treatment.
A randomized clinical trial of 2,858 patients with new-onset and worsening chronic heart failure shows that torsemide and furosemide have no significant difference in clinical or patient-reported outcomes at 12 months. Torsemide is associated with better outcomes for patients with de novo heart failure.
A new Cochrane review has found that human insulin can be stored at room temperature for up to six months without losing potency. This breakthrough research offers hope to millions of people living with diabetes in low- and middle-income countries, particularly those with limited access to refrigeration or healthcare.
SourceCochrane·JournalCochrane Database of Systematic Reviews·TypeSystematic review·DateNov 2, 2023
Researchers have identified polyalthic acid, a compound in copaiba oil, with potent antibacterial activity against Gram-positive bacteria. The study's findings pave the way for developing alternative medications to combat antimicrobial resistance.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·DateOct 17, 2023
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A randomized clinical trial found that cefepime increased neurological dysfunction in adults hospitalized with acute infection, while piperacillin-tazobactam did not. The study involved 2,511 participants and suggested that cefepime may be associated with adverse outcomes.
A study by researchers from National Institutes of Health and Glasgow University found that amlodipine does not activate calcium channels, contradicting earlier concerns. The medication remains a recommended first-line treatment for high blood pressure, reducing deaths from hypertension.
SourceOxford University Press USA·JournalFunction·TypeRandomized controlled/clinical trial·DateOct 12, 2023
A new study reveals that esketamine nasal spray is effective in treating treatment-resistant depression, with 27.1% of patients achieving remission after 8 weeks compared to 17.6% on quetiapine XR. Long-term data shows sustained remission rates at 21.7% for esketamine NS and 14.1% for quetiapine XR.
SourceChampalimaud Centre for the Unknown·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateOct 4, 2023
A University of Melbourne research team is developing an oral therapeutic to restore the activity of common antibiotics used to treat community-acquired bacterial pneumonia. The project aims to combat antibiotic-resistant bacteria and reduce healthcare costs, with potential applications in low- and middle-income countries.
SourceThe Peter Doherty Institute for Infection and Immunity·DateOct 3, 2023
Armida Labs, a UCR-founded pharmaceutical company, has received a $400,000 NIH Small Business Innovation Research grant to develop its breakthrough pancreatic cancer therapy Targefrin. The grant will enable the company to gather industry-standard data for human clinical trials.
SourceUniversity of California - Riverside·DateOct 2, 2023
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A study of 68,000 patients with COVID-19 found that using Paxlovid or Lagevrio significantly reduced mortality and hospitalization rates in those at high risk of progressing to severe COVID-19, regardless of age, race, or virus strain. These medications can be used to treat non-hospitalized patients at high risk of severe disease.
SourceJAMA Network·JournalJAMA Network Open·DateSep 21, 2023
The study found that tenofovir alafenamide fumarate use is associated with a higher incidence of hypertension and statin initiation, particularly among those over 40. Continuous monitoring of blood pressure and lipids for TAF users is recommended.
SourceJAMA Network·JournalJAMA Network Open·DateSep 11, 2023
A team of Chinese and UK researchers has identified superoxide dismutase 1 (SOD1) as a potential target for reversing drug resistance in ovarian cancer. By using nanoparticles to deliver siRNA that reduces SOD1 levels, the study showed reduced growth and decreased resistance to cisplatin in female mice.
SourceXi'an Jiaotong-Liverpool University·JournalCancer Gene Therapy·TypeExperimental study·DateSep 6, 2023
A randomized clinical trial of psilocybin treatment found a clinically significant sustained reduction in depressive symptoms and functional disability. The study's findings support the potential of psilocybin as a novel intervention for major depressive disorder when administered with psychological support.
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Researchers at TUM develop an RNA agent for a lung spray that slows macrophage activity, reducing lung inflammation and fibrosis. The active substance RCS-21 is delivered via an inhaler through a special sugar molecule, showing promise in treating acute inflammatory lung damage.
SourceTechnical University of Munich (TUM)·JournalNature Communications·TypeExperimental study·DateAug 8, 2023
The study provides a comprehensive framework for diagnosing and treating acetaminophen poisoning, emphasizing the importance of early detection and aggressive management. Key findings include the need for prompt assessment and treatment with activated charcoal and N-acetylcysteine, as well as the role of monitoring liver function tests.
SourceJAMA Network·JournalJAMA Network Open·DateAug 8, 2023
Approximately 1 in 5 adults with past-year opioid use disorder received medication for opioid use disorder (MOUD), highlighting disparities in uptake. MOUD disparities affect Black adults, women, unemployed individuals, and those in nonmetropolitan areas.
SourceJAMA Network·JournalJAMA Network Open·DateAug 7, 2023
Researchers at NYU College of Dentistry developed a gene therapy that regulates sodium ion channel activity to alleviate chronic pain. By targeting the specific region where CRMP2 binds to NaV1.7, they were able to reduce sodium influx and quiet down neurons, providing relief from pain in cell and animal studies.
SourceNew York University·JournalProceedings of the National Academy of Sciences·DateJul 27, 2023
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers at California Polytechnic State University have developed a novel method for storing biological materials such as RNA and proteins in a solid-state, resembling a pill or tablet that dissolves in water for on-demand use. This innovation overcomes current limitations in storage and handling, making it easier to access these m...
SourceCalifornia Polytechnic State University·JournalACS Synthetic Biology·TypeExperimental study·DateJul 26, 2023
The study explores resonance between narrative medicine and traditional Chinese medicine, highlighting similarities in case histories. By integrating ancient wisdom with modern approaches, a more compassionate healthcare system can be developed.
SourceCactus Communications·JournalChinese Medicine and Culture·TypeObservational study·DateJul 26, 2023
Researchers at Tokyo University of Science successfully synthesized tanzawaic acid B in large amounts, paving the way for new antibiotic development. The breakthrough method could lead to creation of various compounds for pharmaceuticals, including new antibiotic candidates.
SourceTokyo University of Science·JournalACS Omega·TypeExperimental study·DateJul 19, 2023
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.