Research on asthma and respiratory disease. Covers brain-structure links, prevention trials, weight-loss drugs, and exercise for symptom control.
The aryl hydrocarbon receptor is highly correlated with various aging hallmarks, including mitochondrial abnormalities and cellular senescence. AhR signaling regulates airway inflammation in asthma, suggesting its crucial role in regulating asthma phenotypes.
Children and young adults with allergies or eczema who experience difficulty swallowing may have eosinophilic esophagitis, a chronic inflammatory disease. The condition can cause injury and narrowing of the throat, and its incidence is rising in North America and Europe.
High school students who use cannabis are more likely to develop asthma, with prevalence increasing with frequency of use. The study, published in Pediatric Pulmonology, analyzed data from the 2019 Youth Risk Behavior Surveillance System and found a significant association between cannabis use and asthma.
A recent study by researchers at Columbia University's Mailman School of Public Health found a significant link between cannabis use and current asthma prevalence among US adolescents and adults. The study analyzed data from the 2020 National Survey on Drug Use and Health, finding that individuals who reported cannabis use in the past ...
The ATS 2024 International Conference in San Diego will feature scientific sessions and expert interviews on the latest developments in pulmonary, critical care, and sleep medicine. The conference will cover key subjects such as COVID-19, asthma, COPD, and air pollution.
A groundbreaking study reveals indoor metabolites as key indicators in asthma and allergic rhinitis. Homes with diseased children had higher levels of mycotoxins and synthetic chemicals, while healthy homes were enriched with beneficial microbes and metabolites.
Suicide rates in the US increased across all racial groups between 1999 and 2020, with highest rates among White people and American Indian/Alaska Native persons. Firearms and hanging were the top methods used, with a sharp increase in hangings among women.
Researchers have discovered that immune cells play a crucial role in directing the growth of human lung tissue during development, revolutionizing our understanding of early lung development. The findings also suggest that early immune disturbances could manifest as pediatric lung disease.
A recent study published in Annals of Allergy, Asthma and Immunology examines the effects of climate change on various allergic conditions, including atopic dermatitis, asthma, and seasonal allergies. The research suggests that environmental warming can lead to longer-lasting pollen seasons and increased T2 inflammation.
A landmark study found that 92% of patients with severe asthma can safely reduce inhaled steroid dose and more than 60% can stop all use, minimizing side effects like osteoporosis, diabetes, and cataracts. The SHAMAL study used biologic therapy benralizumab to control severe asthma without steroids.
A recent study published in Annals of Family Medicine explores how technology is changing medical practice, including the use of AI-driven tools to effectively diagnose patients. The study also examines the interplay between fulfillment of basic psychological needs at work and technology use in maintaining clinician well-being.
A new study found that an AI-aided home stethoscope can efficiently detect asthma exacerbation in patients of all ages, including children under 5 years old. The device records and analyzes respiratory sounds, providing valuable information for parents and caregivers to identify symptoms early on.
A recent study analyzed asthma mortality rates in China and the US from 1990 to 2019, revealing substantial differences in mortality rates and risk factors. The study found that smoking was a leading risk factor for asthma mortality in China, while high body mass index (BMI) was a larger public health challenge in the US.
The November issue of CHEST journal features cutting-edge research on asthma, COPD, diffuse lung disease, and thoracic oncology. A new guideline provides updated recommendations for patients with stable COPD, while home spirometry is shown to be less consistent than clinic spirometry in monitoring lung function in patients with asthma.
Dr. Gailen Marshall was installed as president of the American College of Allergy, Asthma and Immunology (ACAAI), succeeding Dr. James Tracy who was elected as president-elect. Dr. Marshall is a renowned allergist and immunologist with extensive experience in clinical practice, research, and academia.
A study found that language difficulties lead to underdiagnosis of allergic conditions like asthma and eczema in children who speak a language other than English. A case report highlights the risks of pharmacy translation software interfering with prescription filling, causing delays in securing life-saving medications.
A survey found that 42% of primary care physicians are unaware of biologic treatments for asthma, and 82% do not get necessary labs to determine treatment options. This lack of knowledge can lead to delayed referrals to asthma specialists and reduced effectiveness in managing symptoms.
A review of 15 years' worth of data found that prenatal vitamin D supplementation reduced rates of asthma and wheezing in children compared to standard prenatal multivitamin. Vitamin D levels during pregnancy were associated with a 50% reduction in asthma and wheezing.
New studies presented at the American College of Allergy, Asthma and Immunology Annual Scientific Meeting highlight the dangers of excess mold on individuals with asthma. Effective methods for getting rid of mold and airborne allergens include HEPA filters, activated carbon filters, and UV-based technology.
The Allergist's Foundation awards grants to support innovative projects addressing health disparities in underserved communities. Six grantees presented their work at the ACAAI National Scientific Meeting, focusing on topics such as cannabis education, food allergy management, and asthma-related outcomes.
A systematic review of prospective studies found that individuals with asthma or rhinitis may be at increased risk of developing long-term symptoms associated with COVID-19. The evidence for these associations was uncertain, highlighting the need for further research.
A large study of 91,460 mother-offspring pairs found no link between prenatal corticosteroid and beta-2 adrenergic agonist exposure and offspring neurodevelopmental issues. The findings suggest these medications are safe for pregnant individuals with asthma.
Researchers found that neighborhoods with better socioeconomic and educational opportunities had lower rates of asthma-related emergency department visits among children under five years old. This suggests that improving social determinants of health in areas with high asthma morbidity may help reduce childhood asthma rates.
Researchers identify immune cells responsible for some hard-to-treat asthma cases, particularly in men who develop asthma later in life. These cells can cause severe inflammatory responses and do not respond to treatment.
Researchers identify cytotoxic CD4+ tissue-resident memory T cells as potential asthma triggers, particularly in older male patients. These cells can cause severe inflammatory responses and make treatment challenging.
Researchers at UCSF found a feedback loop between immune protein IL-31 and nerve cells, which dials back nearby inflammation and promotes skin healing. This discovery could lead to new treatments for conditions like eczema, allergies, and asthma by targeting the nervous system's role in regulating the immune response.
Researchers analyzed UK data to identify patterns of illnesses in individuals leading up to a type 2 diabetes diagnosis. High blood pressure, respiratory tract infections, heart conditions, and asthma were commonly observed, suggesting earlier diagnosis may be possible.
A recent study found that black children with asthma are more likely to receive severe treatment, including breathing treatments, but less likely to be transported to the hospital compared to their white peers. The study highlights the need for improved care and health equity in managing pediatric chronic asthma.
A new study from Texas A&M University finds an association between vaping and asthma in US adolescents who have never smoked conventional tobacco products. The study highlights the need for strategies to tackle e-cigarette use and its adverse health effects.
The September issue of the CHEST journal features research on long COVID, including a review on exercise pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Postacute Sequelae of SARS-CoV-2. Original studies also explore asthma treatment with albuterol-budesonide inhalers and sleep therapy using oronasal masks.
A recent study has found that particular combinations of bacteria in day care dust are linked to an increased risk of wheezing in young children. Researchers identified four categories of microbiota, one of which was associated with a higher incidence of wheezing in children under three years old.
A panel of experts has defined clinical remission in asthma treatment, requiring six criteria met over 12 months. The definition aims to set an aspirational goal for prolonged control and optimize medication adherence.
A University of Houston study found that most of Houston's ozone exceedance is due to transported pollutants from the central and northern US, while local photochemistry contributes to elevated ozone production. The research highlights the importance of reducing emissions at the Houston Ship Channel to mitigate future ozone pollution.
Research shows city living, day care attendance, damp homes, and traffic pollution increase the risk of chest infections in young children. Breastfeeding reduces this risk. Urban environments also affect immune systems before exposure to illnesses.
Babies with more mature gut microbiota at one year old are less likely to develop allergy-related wheeze or asthma. The study, which followed 1074 babies from birth to four years old, found that increased maturity of the gut microbiota was associated with a lower risk of these conditions.
Research found that women exposed to air pollution give birth to smaller babies, with PM2.5 and other pollutants associated with average reductions in birth weight. However, living in greener areas was linked to slightly higher birth weights, suggesting a potential mitigation effect.
People with asthma and COPD face increased breathing difficulties due to climate change's effects on heatwaves, wildfires, and flooding. Experts urge governments to reduce greenhouse gas emissions to mitigate these risks.
Researchers aim to identify genetic risk factors and mechanisms underlying virus-induced asthma, using artificial intelligence-based techniques and patient-derived models. The study may lead to personalized prevention campaigns and mechanism-targeted drugs.
A new study from Aarhus University reveals that indoor air pollution from candle smoke and cooking fumes can cause irritation and inflammation in young individuals with mild asthma. The research found indications of DNA damage and signs of inflammation in the blood, highlighting the need for proper ventilation when cooking or burning c...
A new study reveals that boys who smoke in their early teens may damage the genes of their future children, leading to increased risks of developing asthma, obesity, and low lung function. Researchers investigated epigenetic profiles of 875 people aged 7-50 and found changes associated with fathers' teenage smoking.
Researchers found a common bacterial signature associated with the development of eczema, asthma, food allergy, and hay fever in children. The study suggests that early life influences on gut microbiota may play a key role in the development of these allergies.
A study of Finnish homes found that moulds and yeasts are not linked to increased asthma risk among children. The presence of certain bacteria may actually protect against asthma, suggesting a greater role for indoor microorganisms in preventing the disease.
A new NIH study found that living in a well-resourced neighborhood with access to healthy food, parks, and clean air reduces the risk of childhood asthma. Children born in high-opportunity neighborhoods had significantly lower asthma incidence rates compared to those from low-opportunity areas.
A new study by Harvard Pilgrim Health Care Institute found that residence in neighborhoods with higher opportunity or lower vulnerability is associated with a decreased risk of pediatric asthma. The study used a geographically diverse cohort of over 10,000 children and examined associations between neighborhood attributes and asthma in...
The August issue of CHEST journal features a new clinical practice guideline for managing patients with neuromuscular weakness and a multisociety evidence review on the effect of race and ethnicity on pulmonary function testing interpretation. This is complemented by other research and reviews covering various aspects of chest medicine.
A network meta-analysis found that breathing training combined with aerobic exercise, and yoga training, enhance lung function in adults with asthma. The study highlights the importance of integrating appropriate exercise training into asthma management plans.
A large study published in ERJ Open Research found that people with low levels of vitamin K in their blood are more likely to have poor lung function and experience respiratory issues. The research suggests that vitamin K may play a role in keeping lungs healthy, but further studies are needed to confirm this link.
Researchers at McMaster University developed a new rapid test that can quickly identify eosinophils, key drivers of severe asthma, in complex biological samples. The test uses DNAzymes to track protein signatures and is designed to be simple and adaptable for mass manufacturing.
A new study found that babies with food allergies are more likely to develop asthma and have reduced lung function by six years of age. Early life food allergy was associated with an increased risk of both conditions, even if the allergy resolved or persisted.
The study used electronic health record data from over 200,000 children to describe patterns of pediatric allergies across the US, validating the 'allergic march' pattern. It also found that eosinophilic esophagitis (EoE) is more common among non-White patients than previously reported.
The July issue of CHEST journal features 49 articles on clinically relevant topics, including disability rights and life-sustaining treatment. The journal offers complementary web resources, such as visual abstracts, to expand the reach of its research.
The June issue of CHEST features 49 articles on clinically relevant topics, including asthma, COPD, and critical care. The journal offers web and multimedia resources to expand the reach of its research.
A new study found that food allergy affects all racial and ethnic groups, but is most prevalent among Hispanic, non-Hispanic Black, and Asian individuals. Food allergy rates are also lower in households with higher incomes.
A recent Finnish register-based study found no association between inhaled beta-2 agonist use and reduced risk of Parkinson's disease. Accumulation of alpha-synuclein protein is a key factor in the disease. The study controlled for age, sex, and comorbidities to rule out confounding factors.
Researchers found a peptide from venomous fish Thalassophryne nattereri that controls lung inflammation and airway hyperreactivity. The molecule, TnP, inhibited cytokine production and prevented mucus-producing cell hyperplasia, making it a potential candidate for treating asthma.
Researchers at Texas Biomedical Research Institute have developed a new cell culture model to generate human alveolar macrophages, the most critical immune cells in the lungs. This model allows for easier and inexpensive investigation of lung inflammatory diseases and testing of new therapies.
Researchers found that blocking histamine-releasing factor (HRF) and immunoglobulin E (IgE) interactions may provide relief for patients with severe asthma. The study, published in The Journal of Allergy and Clinical Immunology, suggests two potential therapies, including HRF-2CA and a therapeutic antibody called SPF7-1.
Researchers analyzed data from 120 clinical trials and found no evidence that treatment efficacies differ depending on the number of comorbidities. The study suggests that modest levels of comorbidities do not affect treatment outcomes, providing valuable insights for clinicians to make informed recommendations.
A UC Riverside-led study reveals the Salton Sea environment is toxic, causing sulfuric smells, dust storms, chemicals, and fires that contribute to chronic health conditions like asthma and respiratory illnesses. The study's findings have important public health implications for vulnerable child populations.
A study by University of Technology Sydney found that plants can remove 97% of toxic compounds, including cancer-causing pollutants, from indoor air in just eight hours. This breakthrough discovery highlights the critical role played by indoor plants and green walls in improving air quality.