Research on asthma and respiratory disease. Covers brain-structure links, prevention trials, weight-loss drugs, and exercise for symptom control.
A new study from the University of Toronto finds that childhood neglect is associated with a range of mental and physical health problems in adulthood. The presence of a supportive adult and higher socioeconomic status largely attenuate this relationship.
A new study links a later age at natural menopause with a greater risk of asthma in postmenopausal women. Women using hormone therapy were found to have a significantly increased risk of developing asthma, highlighting the potential role of estrogen in this condition.
A network meta-analysis of patients with asthma found that inhaled corticosteroid combinations with formoterol and short-acting β agonists significantly reduced asthma exacerbations. These therapies also improved asthma control compared to short-acting β agonist monotherapy.
A study from Queen Mary University of London reveals that nearly half of African pupils with asthma symptoms have undiagnosed cases, highlighting the need for better access to diagnosis and treatment. The research found that only a small percentage of diagnosed pupils were using medication effectively.
Cognitive-behavioral therapy (CBT) is a promising intervention for addressing medical non-adherence in pediatric patients with chronic illnesses. CBT successfully integrates principles of learning theory and cognitive science to address behavioral and emotional challenges that affect health outcomes.
A study led by UMass Amherst found no significant improvement in asthma care for Medicaid-insured children compared to those with private insurance. Despite the launch of primary care-oriented Medicaid ACOs in Massachusetts, disparities in quality of care persist, with worsening emergency department/hospital use for children with Medic...
A new study published in MED found that maternal exercise during pregnancy can significantly reduce the risk of asthma in children. The research, which followed over 1,000 mother-child pairs, suggests that engaging in moderate exercise three times a week during pregnancy can lower the risk by nearly half.
A new American Thoracic Society report provides practical frameworks to address systemic racism in asthma care. The report highlights the need to engage affected communities and critically evaluate funding mechanisms to promote antiracism practices in research.
A new study found that exclusively breastfed infants born in a Cincinnati hospital were 22% less likely to develop asthma, suggesting a link between early feeding patterns and long-term health outcomes. The research highlights the importance of supporting exclusive breastfeeding during the critical first days of life.
A study analyzing health data from 780 infants found that early signs of asthma can be predicted by observing dynamic symptom development during the first year. Genetic predisposition, air pollution, and infections were key risk factors contributing to the child's respiratory system adaptation.
A new study found that cystic fibrosis patients with more severe disease characteristics exhibit shorter leukocyte telomere length and greater LTL attrition. This association may accelerate aging and increase susceptibility to age-related diseases, emphasizing the importance of early CF diagnosis and timely therapeutic intervention.
A large study found that women with asthma are more likely to miscarry and require fertility treatment, but most can still have babies. The study analyzed reproductive outcomes for over 700,000 Danish women, finding higher rates of foetal loss and fertility treatment among those with asthma.
A study of 17 million individuals reveals a reciprocal relationship between asthma and type 2 diabetes, with asthma increasing T2D risk by 83% and T2D increasing asthma risk by 28%. Shared factors like hypertension and dyslipidaemia are associated with both conditions.
A new smart mask prototype, EBCare, analyzes chemicals in exhaled breath in real-time, offering personalized health monitoring for respiratory ailments like asthma and COPD. The device's self-cooling system allows for daily wear, while its low cost makes it a promising tool for remote health assessments.
A new registry-based study by the University of Eastern Finland found a significant association between season of birth and airway allergies, including asthma and allergic rhinitis. Being born in autumn or winter was associated with higher rates of these conditions, while summer births showed the lowest incidence.
A new perspective article highlights the impact of wildfires on individuals with COPD and asthma. The five-part Population Health Approach, developed by the University of California, Davis Health, identifies high-risk patients and provides interventions to mitigate poor air quality's negative effects.
A computer algorithm has achieved a 98% accuracy in predicting different diseases by analyzing the color of the human tongue. The proposed imaging system can diagnose various health conditions, including diabetes, stroke, and COVID-19, using a simple and affordable method.
Researchers have identified a crucial molecular signaling pathway in maintaining the skin barrier, which could lead to new treatments for inflammatory skin diseases. The study's findings also suggest that this pathway may contribute to certain types of cancer.
A new Cornell University study reveals that asthma-related emergency room visits spike significantly during periods of high allergenic pollen bloom in metropolitan areas. The research highlights the importance of science-based pollen forecasts to alert vulnerable individuals and prevent unnecessary hospitalizations.
A new study finds that large warehouses across the US emit 20% more nitrogen dioxide pollution, disproportionately affecting communities of color who live near them. This exposure increases the risk of asthma and other life-threatening health conditions.
Research from Monash University found that early exposure to antibiotics can trigger long-term susceptibility to asthma. A molecule called IPA, produced by healthy gut bacteria, has the potential to prevent asthma in children at risk.
Researchers at Chiba University have discovered a new mechanism of ILC2 immune cell development, which may exacerbate allergic diseases. The study found that the induction of GATA3 expression by an ILC2-specific super-enhancer is essential for ILC2 differentiation.
Researchers have discovered several rare types of helper T cells associated with immune disorders such as multiple sclerosis and rheumatoid arthritis. The study found that genetic variants in bidirectional enhancer DNA are linked to specific immune-mediated diseases, including inflammatory bowel disease.
A study published by Nemours Children's Health and Endeavor Health found that states with high COVID-19 vaccination rates saw a significant decrease in pediatric asthma symptoms, with the largest decline seen in the highest quarter of vaccination rates.
Researchers discovered a correlation between higher COVID-19 vaccination rates and lower symptomatic child asthma prevalence. The study suggests that COVID-19 vaccination may provide protection against other human coronaviruses through cross-reactive antibody responses.
A new study reveals a direct connection between childhood air pollution exposure and adult bronchitis symptoms, suggesting that subtle effects on the respiratory system can persist into adulthood. The research, based on the USC Children's Health Study, found that even when adjusting for asthma or bronchitis symptoms in childhood, expos...
Researchers found that mice lacking the G900 region exhibit reduced inflammatory response and suppressed Th2 differentiation when exposed to allergens. This discovery highlights the importance of the G900 gene enhancer in regulating immune responses and has implications for personalized treatments and asthma care.
Researchers found that colder temperature exposure increases oxidative stress in the nasal cavity, leading to worsened asthma symptoms in children. The study used nasal fluid samples and measured malondialdehyde (MDA) levels as a biomarker of oxidative stress.
Climate change is increasing the frequency and severity of wildfires in Canada, resulting in increased exposure to hazardous wildfire smoke. Health care practitioners play a crucial role in mitigating the health effects of wildfire smoke by providing guidance and support to vulnerable populations.
Researchers in Brazil have developed bread with probiotic yeast that may help combat asthma by reducing airway inflammation and hyperresponsiveness. The bread's probiotic properties were shown to attenuate asthma symptoms in mice, suggesting potential for a new treatment approach.
The American College of Allergy, Asthma & Immunology (ACAAI) has issued a position paper on the safety of administering live vaccines to patients treated with dupilumab. The review suggests that treatment should not be stopped, but rather, shared decision-making between doctors and patients is recommended to weigh risks and benefits.
A study published in the European Respiratory Journal found that children exposed to weed pollen in urban environments are at higher risk of developing respiratory health problems, including asthma. However, tree canopy can mitigate this effect to some degree.
A study finds that prostaglandin E2 elicits mast cells to suppress inflammation by creating soluble ST2, blocking proinflammatory cytokine actions. The findings suggest a promise in targeting PGE2 with therapeutics to treat severe asthma.
The American College of Chest Physicians' CHEST Critical Care and CHEST Pulmonary journals have been indexed with the Directory of Open Access Journals (DOAJ), enhancing their open access content's accessibility and usage. The indexation is attributed to strong editorial boards led by Hayley Gershengorn and Matthew Miles.
Researchers from Mount Sinai will present new research on long COVID, lung cancer, asthma, and sleep apnea at the ATS 2024 International Conference. The studies aim to improve diagnosis and care for these conditions.
Only 14.5% of adult patients with moderate or severe asthma are prescribed the recommended Single Maintenance and Reliever Therapy (SMART) combination inhaler regimen. Older age and Medicare insurance are associated with not being prescribed SMART, suggesting providers may resist changing treatment regimens for these groups.
Replacing diesel school buses with electric ones can yield up to $247,600 in climate and health benefits per individual bus, according to a new study. The benefits include reduced greenhouse gas emissions and lower rates of adult mortality and childhood asthma.
A world-first clinical trial found that finding and treating people with undiagnosed asthma or COPD improves their health and reduces healthcare visits. The study, which involved 508 patients, showed that those treated by a lung specialist and educator averaged fewer healthcare visits and improved symptoms compared to usual care.
Researchers at UTHealth Houston found a significant link between e-cigarette use and earlier age of asthma onset in U.S. adults. Adults who reported e-cigarette use in the past 30 days were 252% more likely to develop asthma earlier than those who did not use e-cigarettes.
Researchers found a significant relationship between insomnia, depression, and obstructive sleep apnea in people with asthma, leading to poor asthma control. Regular screening for sleep quality and co-existing mood disorders can help improve overall quality of life.
A new study estimates that gas stove use in U.S. households may be responsible for up to 200,000 childhood asthma cases annually, with high levels of nitrogen dioxide exposure also causing thousands of deaths. The research found that even electric stoves produce no NO2, and that ventilation is key to reducing pollutant exposures.
The American Journal of Respiratory and Critical Care Medicine has released the ATS 2024 International Conference Abstracts, featuring research on heat exposure and RSV among other topics.
A study led by Emily Skeen, MD, found a strong correlation between neighborhood environmental and social conditions and the likelihood of exacerbation-prone asthma among children. The researchers used the Child Opportunity Index to predict the risk of severe asthma in urban areas.
A University of California, Riverside study found that communities in unincorporated areas lack basic critical infrastructure, including healthcare access. Caregivers perceive U.S.-based physicians as not providing sufficient information, while Mexican-based physicians are seen as offering better care.
A team of scientists has identified a specific gene expression pattern associated with an increased risk of childhood asthma. By understanding this mechanism, they aim to develop novel drugs that can correct the defense defect and prevent the progression of the disease.
A large study of over 27,000 pediatric patients found that SARS-COV-2 infection does not increase the risk of asthma development. However, children with known risk factors for asthma were more likely to associate with new SARS-COV-2 diagnoses.
Researchers have identified TL1A, an alarmin molecule, as a key trigger for allergic reactions in respiratory diseases like asthma and rhinitis. The molecule cooperates with interleukin-33 to stimulate immune cells, leading to inflammation and treatment targets are being explored.
Climate change, pollution, and biodiversity loss are damaging our immune systems, increasing the risk of diseases like asthma and cancer. Improving the environment offers effective protection and can have a powerful return on investment, saving $3 in healthcare costs for every $1 spent on mitigation.
Scientists at King's College London discovered that limiting damage from an asthma attack could stop the disease by blocking a process that causes epithelial cell death. The findings suggest that preventing this damage could also prevent long-term inflammation, wound healing, and infections in asthma sufferers.
A researcher at the University of Arizona is using a $750,000 NIH grant to develop methodology for reducing asthma risks among nurses. Preliminary survey data suggest that nurses prioritize lower asthma risks over increased infection risks.
A new study by UT researchers links air pollution in Austin neighborhoods to increased asthma-related emergency room visits, particularly among Black and Latinx residents. The study highlights the urgent need for targeted interventions to mitigate pollution in high-asthma-burden neighborhoods.
A study by Washington State University found that exposure to multiple air pollutants was associated with asthma symptoms among elementary school children. The researchers identified 25 combinations of air pollutants linked to asthma, with one group from a lower-income neighborhood experiencing higher exposure levels.
A new study quantifies the significant health impacts of oil and gas flaring in the US, resulting in over 700 premature deaths and 73,000 asthma exacerbations annually. The research highlights the need for stronger controls on emissions from this sector to improve public health and mitigate climate change.
A study of 5,279 children found that early-life exposure to air pollution significantly increases the risk of developing asthma by early and middle childhood. The study highlights the need for targeted environmental interventions and greater health equity in urban communities.
A new study by Purdue University finds that cooking on a gas stove can emit more nanocluster aerosol into the air than vehicles running on gas or diesel. This tiny particle pollution could increase the risk of developing asthma and other respiratory illnesses, especially for children.
A study of 236,506 patients found that poorly controlled asthma generates more greenhouse gas emissions than well-controlled asthma. The excess emissions are equivalent to those from over 124,000 homes in the UK each year, with most coming from inappropriate SABA use.
The American Academy of Otolaryngology has released a new clinical practice guideline supporting clinicians with evidence-based recommendations on immunotherapy for inhalant allergies. The guideline provides 12 key action statements to guide treatment, aiming to optimize patient care and reduce unnecessary variation in management.
Researchers optimized polygenic risk scores using ancestrally diverse genomic data to improve accuracy across diverse populations. The recalibrated tests provided a more accurate assessment of disease risk for individuals with varied ancestral backgrounds.
The Changing High-Risk Asthma in Memphis through Partnership (CHAMP) program significantly decreased healthcare use related to asthma by addressing access to care, fragmented care, and social needs. After one year of enrollment, results showed a 48% reduction in ED visits, 68% reduction in inpatient and observation visits.
The aryl hydrocarbon receptor is highly correlated with various aging hallmarks, including mitochondrial abnormalities and cellular senescence. AhR signaling regulates airway inflammation in asthma, suggesting its crucial role in regulating asthma phenotypes.