A new risk equation could lead to a significant reduction in statin prescriptions, with 28.3 million adults potentially eligible instead of 45.4 million under current guidelines. The PREVENT equations incorporate recent insights into the biology of cardiovascular disease and remove race as a factor.
SourceUniversity of Pittsburgh·JournalJAMA Internal Medicine·TypeData/statistical analysis·DateJun 10, 2024
A study found that ACS, elevated HbA1c and TG levels, and higher SYNTAX scores are risk factors for the progression of native coronary atherosclerosis after PCI. Higher rates of hyperuricemia and acute coronary syndrome were also observed in patients with progressive disease.
SourceCompuscript Ltd·JournalCardiovascular Innovations and Applications·DateJun 6, 2024
A recent Cleveland Clinic-led study found that high levels of the sugar alcohol xylitol are associated with an increased risk of cardiovascular events like heart attacks and strokes. The research team identified a link between xylitol consumption and elevated platelet activity, which can lead to blood clots and thrombosis.
SourceCleveland Clinic·JournalEuropean Heart Journal·DateJun 6, 2024
Research finds insulin levels correlate with triglycerides, ApoB, non-HDL cholesterol, and free cholesterol in women with atherosclerotic coronary disease. The study suggests these laboratory-associated flags indicate early coronary atherosclerosis in both diabetic and non-diabetic women.
SourceBentham Science Publishers·JournalThe Open Biomarkers Journal·DateMay 24, 2024
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A Danish-Spanish collaboration is launching the REACT initiative to develop early detection and prevention methods for atherosclerosis. The project aims to identify new means to detect atherosclerosis at earlier stages and at a younger age, enabling precision treatment and prevention.
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·DateMay 16, 2024
A new study published in Journal of the American Geriatrics Society found that greater community mobility is significantly associated with better cognitive function in individuals aged 52 and older. The association was strongest among those at low risk for atherosclerotic cardiovascular disease.
SourceWiley·JournalJournal of the American Geriatrics Society·DateMay 15, 2024
Cardiovascular biomarkers strongly associated with cardiovascular events and mortality. Adding biomarkers to established risk factors improved heart failure and mortality prediction, but only slightly enhanced atherosclerotic disease risk prediction.
Researchers found transformed smooth muscle cells driving atherosclerosis by proliferating and resisting cell death, suggesting potential treatment with anticancer therapies. A common cancer drug reduced plaque size in mouse models, but further studies are needed for clinical translation.
SourceColumbia University Irving Medical Center·JournalCirculation·TypeExperimental study·DateMay 1, 2024
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A new genetic testing procedure identifies patients at high cardiovascular risk due to clonal haematopoiesis and carotid artery stenosis. This allows for early detection of increased mortality and a personalized cardiovascular risk profile, enabling therapy adaptation and prevention of atherosclerotic disease progression.
SourceMedical University of Vienna·JournalJournal of the American College of Cardiology·DateApr 30, 2024
A study of 26,000 US participants found that both individual- and area-level social determinants contribute to cardiovascular disease risk. The findings suggest that these factors should be considered in future risk assessment tools, especially for Black individuals.
SourceJAMA Network·JournalJAMA Network Open·DateApr 26, 2024
Researchers discovered that eliminating progerin from vascular smooth muscle cells prevents atherosclerosis and improves life expectancy in HGPSrev mice. This finding suggests a potential therapeutic strategy for treating progeria, an extremely rare genetic disease affecting 1 in every 20 million people.
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateApr 22, 2024
Researchers have made progress in understanding atherosclerosis, identifying potential new approaches for early detection and therapy. The study found that TREM2 regulates the activity of macrophages, playing an important role in forming unstable plaques that increase heart attack and stroke risk.
SourceMedical University of Vienna·JournalNature Cardiovascular Research·DateMar 13, 2024
Researchers found that Kupffer cells in liver respond to high cholesterol by removing excess, revealing the liver's role in regulating cholesterol levels. This discovery suggests atherosclerosis is a systemic disease affecting multiple organs.
SourceKarolinska Institutet·JournalNature Cardiovascular Research·TypeExperimental study·DateMar 11, 2024
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers at UVA Health System have discovered genetic clues that may help identify people at risk of cardiovascular disease, including atherosclerosis. The study identified 20 locations on chromosomes that influence protein production, shedding light on why smooth muscle cells sometimes are beneficial and sometimes harmful.
A new study published in Radiology found that coronary artery calcium scoring can identify patients with a low risk of heart attacks or strokes. Patients with a zero coronary artery calcium score showed very low risk of major adverse cardiovascular events, suggesting they may not require invasive coronary angiography.
SourceRadiological Society of North America·JournalRadiology·DateMar 5, 2024
A new study found that MERRICAL, a long non-coding RNA sequence, is involved in recruiting macrophages to the arterial wall and promotes atherosclerosis progression. Reducing MERRICAL expression levels using inhibitors significantly reduced atherosclerosis and aortic lesion formation.
SourceBrigham and Women's Hospital·JournalCell Reports·TypeExperimental study·DateFeb 29, 2024
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers found a higher risk of heart disease or stroke among patients who stopped taking aspirin, but no significant difference in major bleeding risk. The study suggests that patients already safely taking aspirin may continue to benefit from its use without increased risk.
SourceUniversity of Galway·JournalCirculation·TypeMeta-analysis·DateFeb 27, 2024
A Swedish study of over 9,000 men found that those who were physically fit in adolescence had a lower risk of atherosclerosis nearly 40 years later. The researchers used advanced imaging technology to examine plaques in the coronary arteries and found associations with both good cardiorespiratory fitness and muscle strength in youth.
SourceLinköping University·JournalBritish Journal of Sports Medicine·TypeObservational study·DateFeb 22, 2024
A new study suggests that finasteride, a common hair loss and prostate drug, may also lower cholesterol levels and reduce cardiovascular disease risk in men. In mice, the researchers found significant correlations between finasteride use and lower cholesterol levels, as well as reduced inflammation and atherosclerosis progression.
SourceUniversity of Illinois College of Agricultural, Consumer and Environmental Sciences·JournalJournal of Lipid Research·DateFeb 20, 2024
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers discovered that consuming over 22% of daily calories from protein can lead to increased activation of immune cells contributing to atherosclerotic plaque formation. Leucine, an amino acid found in animal-derived foods, plays a disproportionate role in driving pathological pathways linked to atherosclerosis.
SourceUniversity of Pittsburgh·JournalNature Metabolism·DateFeb 19, 2024
Researchers have discovered a new treatment that enhances the body's natural defences against atherosclerosis in patients with rheumatoid arthritis. Treating arthritic mice with RvT4 reduces blood vessel inflammation by re-programming macrophages to release stored lipids.
SourceQueen Mary University of London·JournalNature Communications·TypeExperimental study·DateFeb 5, 2024
Researchers discovered that reducing cholesterol levels in mice with advanced atherosclerosis leads to a decrease in the number of smooth muscle-derived cells causing plaque growth, while preserving stabilizing cell types. This finding opens up new opportunities for targeted therapies.
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalNature Cardiovascular Research·TypeExperimental study·DateFeb 1, 2024
The study found that APOE4 carriers have elevated LDL cholesterol levels, increasing their risk of developing subclinical atherosclerosis. In contrast, APOE2 carriers have lower cholesterol and reduced atherosclerosis prevalence.
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalCirculation Research·TypeRandomized controlled/clinical trial·DateJan 23, 2024
UAB researchers have created a 3D, three-layer nanomatrix vascular sheet that mimics human atherosclerosis, enabling high-throughput drug screening. The model replicates key features of the disease and has been validated with two classic atherosclerosis drugs.
SourceUniversity of Alabama at Birmingham·JournalBiomaterials·TypeExperimental study·DateJan 12, 2024
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers have discovered a novel mechanism by which elevated blood pressure transforms muscle cells into 'foam cells' that form the building blocks of plaque buildup in arteries. This finding provides crucial insights for developing new therapies to control or reverse arterial disease.
SourceQueen Mary University of London·JournalAdvanced Science·DateJan 5, 2024
The Chinese expert consensus on CMVD diagnosis and treatment emphasizes standardized methods, six areas for classification, and recommendations for non-invasive diagnostic techniques. The consensus also highlights the need for further research into the pathogenesis of CMVD and its impact on cardiovascular events.
SourceSichuan International Medical Exchange and Promotion Association·JournalMedComm·TypeLiterature review·DateDec 28, 2023
A recent study published in Nature reveals that mitochondrial dysfunction disrupts dietary lipid processing in enterocytes, leading to abnormal fat accumulation and impaired nutrient delivery. The findings provide new insights into the gastrointestinal symptoms of mitochondrial disease and may lead to novel therapeutic approaches.
SourceUniversity of Cologne·JournalNature·TypeExperimental study·DateDec 20, 2023
Researchers at UVA Health System created an 'atlas of atherosclerosis' revealing critical processes that form harmful plaque buildup. The study provides unprecedented insights into atherosclerosis and its impact on coronary artery disease, heart attacks, and strokes.
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Significant racial and ethnic disparities in atherosclerotic cardiovascular disease treatment were found in a study of 5,218 adults. The disparities persisted despite optimal recommended therapies, underscoring the need for sustained efforts to achieve better outcomes for all patients regardless of their background.
SourceJAMA Network·JournalJAMA Network Open·DateDec 1, 2023
A new study reveals that younger people are more vulnerable to the effects of high blood cholesterol and hypertension, atherosclerosis can be reversed if risk factors are controlled early enough. The study suggests aggressive control of cardiovascular risk factors at younger ages.
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalJournal of the American College of Cardiology·TypeRandomized controlled/clinical trial·DateNov 20, 2023
A post-hoc analysis of the CANTOS trial found no effect of canakinumab on frailty incidence or self-reported function. The study suggests that inflammation may not be a causal factor in the development of frailty in these participants.
SourceBrigham and Women's Hospital·JournalAging Cell·TypeExperimental study·DateNov 14, 2023
A recent study analyzing global and national trends of atherosclerosis found an increasing trend in incidence from 1990 to 2019, driven by adults aged 20–54. The burden of the disease is particularly concerning in low- and middle-income countries, where it is rising significantly due to lifestyle factors and aging populations.
SourceCactus Communications·JournalChinese Medical Journal·TypeData/statistical analysis·DateNov 2, 2023
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers have identified a specific microRNA molecule, miR-206, that plays a key role in atherosclerosis. By blocking its action, they were able to prevent the development of atherosclerotic lesions in mouse models and human cells. This discovery opens up new avenues for targeted therapies.
SourceLudwig-Maximilians-Universität München·JournalScience·DateNov 2, 2023
Greater PTSD symptoms were associated with higher carotid atherosclerosis and brain small vessel disease among midlife women. Women carrying the APOEɛ4 gene showed poorer cognitive performance in response to PTSD.
SourceJAMA Network·JournalJAMA Network Open·DateNov 2, 2023
A post hoc analysis of 10,678 participants with atherosclerotic cardiovascular disease found no significant difference in heart attack, stroke, or death risk between enteric-coated and uncoated aspirin. Enteric-coated aspirin may offer reduced bleeding risk, but more research is needed to confirm its benefits.
SourceJAMA Network·JournalJAMA Cardiology·DateOct 4, 2023
A new study reveals that COVID-19 triggers a dangerous immune response in hardened fatty deposits lining the heart's largest blood vessels. This inflammation can lead to immediate and longer-lasting heart issues, including plaque rupture and blockage of blood flow.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature Cardiovascular Research·TypeExperimental study·DateSep 28, 2023
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers found that people with high blood pressure while lying flat on their backs had a higher risk of heart attack, stroke, and premature death. The study suggests that measuring blood pressure in different body positions may help identify cardiovascular disease risk.
A new CNIC study confirms that controlling traditional cardiovascular risk factors can prevent Alzheimer's disease and dementia. Maintaining a low cardiovascular risk is linked to preserved cerebral glucose metabolism, indicating better brain health.
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalThe Lancet Healthy Longevity·DateAug 30, 2023
Muvalaplin, an oral small molecule inhibitor, significantly lowered lipoprotein(a) (Lp[a]) levels in a first-in-human phase 1 study. The treatment showed promise in reducing Lp[a] levels by up to 65% without tolerability concerns.
A new study found that arterial stiffness is a novel cause of premature heart damage among adolescents, leading to increased blood pressure and insulin resistance. The study discovered that adolescents with high arterial stiffness had a 23-27% increased risk of structural heart damage.
SourceUniversity of Eastern Finland·JournalAtherosclerosis·DateAug 15, 2023
Researchers investigate how exposure to endocrine-disrupting chemicals in plastics may increase atherosclerosis and CVD risk, particularly in children. The study aims to establish a novel therapeutic target for chemical-induced CVD and explore gene-EDC interactions.
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers at La Jolla Institute for Immunology and Augusta University have identified a link between
SourceLa Jolla Institute for Immunology·JournalNature Immunology·TypeExperimental study·DateAug 10, 2023
A study published in Stroke found significant disparities in stroke risk factors between Black and non-Black adults. However, after one year of intensive medical intervention, some risk factors were reduced in Black adults.
SourceAmerican Heart Association·JournalStroke·DateAug 3, 2023
A team of researchers identified a specific subtype of complement-producing macrophages in atherosclerotic lesions that exacerbate plaque necrosis and cardiovascular events. The study suggests a potential therapeutic target to control complement activation within cells, which may also apply to other chronic inflammatory diseases.
SourceMedical University of Vienna·JournalImmunity·DateJul 27, 2023
Researchers found a strong association between certain gut bacteria and coronary atherosclerotic plaques, which can lead to heart attacks. The study analyzed gut bacteria and cardiac imaging data from over 8,900 participants and identified Streptococcus species as key players.
SourceUppsala University·JournalCirculation·TypeObservational study·DateJul 12, 2023
A cohort study found that U.S. veterans with atherosclerotic cardiovascular disease residing in historically redlined neighborhoods still experience higher prevalence of traditional cardiovascular risk factors and adverse cardiovascular events. Redlining's adverse association persists even decades after its discontinuation.
SourceJAMA Network·JournalJAMA Network Open·DateJul 11, 2023
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A new proposal suggests adopting an 'adolescent cholesterol passport' to prevent atherosclerosis, a leading cause of death worldwide. The tool would involve regular cholesterol screenings starting at age two, with the goal of detecting familial hypercholesterolemia and other genetic conditions early on.
SourceUniversity of Eastern Finland·JournalFrontiers in Pediatrics·DateJun 28, 2023
A new study by CNIC researchers reveals that low-grade systemic inflammation triggered by subclinical atherosclerosis accelerates epigenetic aging in otherwise healthy young individuals. The study found a strong association between atherosclerosis progression and accelerated biological age, with potential reversibility through lifestyl...
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalEuropean Heart Journal·TypeCase study·DateJun 21, 2023
A new study shows that saracatinib reduces inflammation in patients with atherosclerotic cardiovascular disease by more than 90% and boosts genes that help clean up plaque deposits. The experimental cancer drug may offer an effective therapy for cases where standard treatment fails to help.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature Cardiovascular Research·TypeExperimental study·DateJun 8, 2023
The study used transcranial photobiomodulation (tPBM) to stimulate the prefrontal cortex, a region involved in cognitive function. The results showed that tPBM modulated hemodynamic and metabolic activities in a wavelength- and site-specific manner.
SourceSPIE--International Society for Optics and Photonics·JournalNeurophotonics·DateJun 6, 2023
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A new study published in the European Heart Journal found that plant-based diets can play a significant role in reducing blocked arteries and lowering the risk of heart and blood vessel diseases. The analysis of 30 randomised trials with over 2,300 participants showed a 14% reduction in artery-clogging lipoproteins.
SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·TypeMeta-analysis·DateMay 24, 2023
Researchers found that high-fat diets increase levels of gut-derived bacterial toxins and systemic inflammation, promoting atherosclerosis. The study suggests targeting interventions for individuals at risk of developing heart disease.
SourceAmerican Society for Biochemistry and Molecular Biology·JournalJournal of Lipid Research·TypeExperimental study·DateMay 11, 2023
CARMN is a long noncoding RNA that regulates contractility in both blood vessels and the gastrointestinal tract. Without CARMN, mice cannot survive due to impaired GI tract contraction, leading to conditions like intestinal pseudo-obstruction.
SourceMedical College of Georgia at Augusta University·JournalGastroenterology·DateMay 9, 2023
A randomized controlled trial shows that a best endovascular treatment first revascularisation strategy is more effective in preventing major amputation and death than a vein bypass first strategy for patients with chronic limb-threatening ischaemia. The study, BASIL-2, recruited 345 patients from the UK, Sweden, and Denmark and found ...
SourceUniversity of Birmingham·JournalThe Lancet·TypeRandomized controlled/clinical trial·DateMay 2, 2023
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
The study found that statin use for primary prevention was low among all racial and ethnic groups, despite varying levels of 10-year ASCVD risk. Improving access to care may help increase equitable use of primary prevention statins in Black and Hispanic adults.
The VALOR-QI program will provide a blueprint for quality care improvement, focusing on high-risk patients and addressing health equity gaps. It will offer education, staff training, monitoring, and other steps to achieve better compliance with cholesterol management.
Researchers at Houston Methodist discovered a way to reverse infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein. The study showed that this protein, called serum opacity factor, lowered HDL cholesterol levels by over 40% in three hours and restored fertility in the mice.
SourceHouston Methodist·JournalJournal of Lipid Research·TypeExperimental study·DateMar 14, 2023
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
A new study found that walking an additional 500 steps per day was associated with a 14% lower risk of heart disease, stroke or heart failure. This benefit is significant for older adults, as most studies have focused on early-to-midlife adults.
A study found that over 80% of American adults with type 2 diabetes meet the criteria to use GLP-1 RAs or SGLT2is, but only a small percentage are using them. The medications have a substantially higher cost than current first-line treatments, making it difficult for patients to access them.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateFeb 27, 2023
A recent study published in the Journal of the American Heart Association found that irregular sleeping habits may increase the risk of developing atherosclerosis among adults older than 45. Maintaining regular sleep schedules can help reduce cardiovascular risk for aging adults and improve overall health.
SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateFeb 15, 2023