Articles tagged with Cardiovascular Disease
Research found social vulnerabilities such as poverty and minority status linked to increased cardiometabolic risk during pregnancy. The study analyzed nearly 19 million pregnancies in US counties from 2016-2020 and found that four leading cardiometabolic risk factors were associated with some social vulnerability.
Researchers analyzed 30 years of cardiovascular mortality data from the US and UK, finding that lead exposure contributes more to CVD death risks in the US. The study also revealed a steady decline in cardiovascular deaths associated with all environmental factors in both countries.
A study of 9,303 US adults found that people with cardiovascular disease were less likely to use wearable devices, highlighting disparities in access and use. The research emphasizes the need to ensure equitable access to wearables to benefit high-risk populations.
Survival rates for in-hospital pediatric cardiac arrest events have increased significantly between 2000 and 2021. Children with a history of cardiovascular disease showed slower improvement in survival rates compared to those without a history of CVD.
Researchers found that vaping and smoking e-cigarettes led to greater constriction of the brachial artery and worse heart rate variability, indicating activation of the sympathetic nervous system. Vaping was also associated with poorer performance on exercise stress testing compared to non-nicotine users.
A new study from the University of Missouri School of Medicine found that short-term exposure to reduced physical activity and increased sugar consumption disrupts insulin response in blood vessels, with men more prone to vascular insulin resistance. In contrast, young women are protected against this condition.
A new study using wearable devices found that moderate-to-vigorous physical activity significantly reduces cardiovascular disease risk, even when total physical activity volume is increased. Increasing the proportion of intense physical activity within overall activity levels has an additional substantial benefit.
Dr. Ivor Benjamin is recognized for his decades-long commitment to cardiovascular science, with a focus on proteostatic networks, stem cell biology, and redox homeostasis. He has led numerous initiatives to expand biomedical research and patient care, aiming to reduce health disparities and improve healthcare equity.
Two studies found that cigarette smoke and e-cigarette vapor have similar cardiovascular effects due to airway irritation. This irritation can lead to vascular damage and impaired blood vessel function. The research suggests that dual product use may be worse than single product use, highlighting the need for stricter regulations.
Dr. Paul Muntner receives the 2022 Joseph A. Vita Award for his work on identifying cardiovascular disease risk factors and improving hypertension prevention and treatment. He is recognized for his studies on environmental factors, blood pressure measurements, and African American adults.
A new study by Syracuse University researchers found that more conservative state policies were associated with higher mortality rates among US workers. The study suggests that liberalizing policies on gun safety, labor, and tobacco taxes could lower mortality rates.
Dr. Bibbins-Domingo's research focuses on racial disparities in cardiovascular disease prevention, incidence, and outcomes. She explores long-term effects of early and poorly treated high blood pressure and develops strategies to prevent and manage CVD.
Two NIH-funded studies show long-term e-cigarette use can impair blood vessel function, increasing the risk for cardiovascular disease. The findings also suggest combining e-cigs with tobacco may increase health risks compared to using them individually.
Dr. Eldrin F. Lewis, a clinician scientist at Stanford University School of Medicine, has been awarded the 2022 Clinical Research Prize by the American Heart Association. His work focuses on improving quality of life and care delivery models for patients with heart failure through point-of-care initiatives.
The American Heart Association honored Drs. Harriette Van Spall and Erica Gunderson with the 2022 Dr. Nanette K. Wenger Research Goes Red Award for their groundbreaking study on sex-specific clinical outcomes of heart failure patients. The research found that women experienced improved outcomes after receiving transitional care service...
The University of Missouri has earned an $8 million grant from the National Institutes of Health to expand its National Swine Resource and Research Center. The center will support research using genetically modified pigs to study human diseases, with a focus on therapies that can be translated from pig models to humans.
A new study found that living in a community with easy access to grocery stores and affordable, healthy food is associated with lower heart failure death rates. The research analyzed data from nearly 3,000 counties in the US and found that food insecurity is linked to increased rates of death from heart failure.
A large UK Biobank study found that COVID-19 infection is associated with a heightened risk of poor cardiovascular health and death, particularly among those who require hospital admission. The risk remains elevated for some time after the initial infection.
A new protein called TANGO2 helps mobilize heme from sites of synthesis and storage for use in cells. Understanding its role may lead to therapeutic strategies for diseases associated with heme dysregulation.
The study reveals that a genetic mutation can accelerate the body's internal clock, leading to improved adjustment to shift work schedules. The findings have implications for understanding the health consequences of circadian misalignment and developing medical treatments.
A recent study published in Journal of Science and Medicine in Sport reveals that high aerobic fitness does not protect children from metabolic syndrome. In contrast, a lower risk was observed when considering body size and composition.
A new study using the American Heart Association framework provides evidence that sleep is integral to preserving heart health. Sleep metrics add independent predictive value for CVD events over and above the original 7 CVH metrics.
A study of over two million individuals in Denmark found that mothers with hypertensive disorder of pregnancy have a higher mortality risk in their offspring. The study shows an association between maternal HDP and various cause-specific deaths, including cardiovascular disease and cancer.
A new study analyzing data from 17 studies reveals no correlation between high intake of refined grain foods and the risk of cardiovascular disease. The meta-analysis found that consuming more refined grains was actually associated with a lower risk of heart disease.
A global study found that cardiovascular disease risk factors are largely the same for men and women, except for high LDL levels which affect men more. Women have a lower risk of heart attack and stroke due to their estrogen's effect on vessel walls and liver function.
A new study found that soluble urokinase plasminogen activator receptor (suPAR) levels are significantly higher in patients with heart failure, predicting both heart failure and death. When combined with traditional measures like BNP, suPAR's predictive ability increases.
A study published in Hypertension Research suggests that weight gain from childhood with an optimal muscle-to-fat mass ratio may indicate excellent vascular health. The researchers found that increasing muscle mass was associated with optimal vascular function, especially in males.
A team of scientists at Scripps Research and Calibr discovered a naturally occurring metabolite called myristoylglycine that can convert white fat cells into brown fat cells, potentially treating obesity and related diseases. The breakthrough uses a novel drug discovery method to identify endogenous metabolites with therapeutic potential.
A national study found that patients with cardiovascular disease had a higher mortality rate than those without, but this association was largely due to shared risk factors. Myocardial injury was common among critically ill COVID-19 patients and associated with poor outcomes.
Research highlights growing evidence connecting hot flashes to an elevated risk of cardiovascular disease in women, including poorer health profiles and increased risk of heart disease events. Women experiencing more frequent or severe hot flashes may benefit from targeted cardiovascular reduction efforts as they age.
Researchers found that metformin targeted 30 genes associated with atrial fibrillation, showing direct effects on gene expression for eight. The study suggests metformin may be a promising candidate for treating atrial fibrillation due to its potential to reduce the risk of complications such as stroke and heart failure.
Children with homozygous familial hypercholesterolemia are diagnosed earlier and have higher untreated LDL-C levels than adults, while those not identified early miss out on decades of life-saving treatment. This study emphasizes the need for universal screening to identify children with HoFH or heterozygous familial hypercholesterolemia.
A study in C. elegans suggests that disrupting meiosis in reproductive cells accelerates aging and triggers a decline in healthspan, similar to humans. The research highlights the importance of reproductive fitness for overall health, with potential applications for early detection and treatment of age-related diseases.
Researchers at CNIC have identified metoprolol as a neuroprotective agent after a stroke, greatly reducing cerebral inflammation and neuronal death. The study's findings suggest that metoprolol may also offer benefits in treating severe Covid-19.
Particle radioactivity from radon in air pollution increases toxicity and risk of death from cardiovascular disease, especially from heart attack and stroke. Researchers used spatiotemporal predictions to estimate exposure and found that higher gross beta-activity levels increased the risk of death from these conditions.
A randomized clinical trial found that time-restricted eating (TRE) is safe and feasible for 24-hour shift workers, improving glucose levels and blood pressure in those with cardiometabolic risk factors. Participants who followed a TRE pattern experienced improved quality of life and reduced bad cholesterol.
A clinical trial conducted by Salk Institute and UC San Diego Health found that time-restricted eating improved measures of health and wellbeing in firefighters. The study showed that a 10-hour eating window reduced VLDL cholesterol, improved mental health, and decreased alcohol intake.
Scientists have identified long interspersed nuclear element-1 (L1) RNA as a promising new target for treating progeroid syndromes. Increased L1 RNA expression in cells from patients with these disorders led to deactivation of an enzyme, causing cell aging.
A randomized controlled trial found that combining time-restricted eating (TRE) and high-intensity interval training (HIIT) improved long-term glycemic control and reduced fat mass in women with overweight/obesity. The study also showed increased cardiorespiratory fitness.
Researchers developed an AI algorithm to assess retinal vasculature, predicting cardiovascular disease and death. The model captured half to two-thirds of circulatory disease deaths in those most at risk, outperforming traditional risk frameworks.
A cross-sectional study of over 70,000 Asian Americans found significant variation in obesity prevalence among subgroups, with Filipino Americans having the highest rate at 28.7% and Chinese Americans the lowest at 13.2%. The study highlights the need for tailored strategies to address obesity disparities among Asian American populations.
Research finds significant variation in obesity prevalence among Asian American subgroups, with health risks starting at lower BMIs. The study suggests using specific criteria for Asian populations to accurately assess obesity-related health risks.
Women with severe preeclampsia treated with extended-release nifedipine during labor and delivery had lower rates of dangerously high blood pressure, reducing the need for IV treatment. This study contributes to optimal management of hypertension during pregnancy and delivery.
A recent study found that 38% of people with cardiovascular disease were food insecure in 2017-2018, more than doubling from two decades earlier. Food insecurity exacerbates existing racial and ethnic health disparities and can lead to increased risk for cardiometabolic risk factors.
The Leducq Foundation has awarded $7.5 million to UVA researchers, led by Mete Civelek, to investigate sex differences in atherosclerosis and $8 million to Coleen McNamara to advance immunotherapy for cardiovascular disease. These projects aim to improve understanding of heart disease and develop new treatments.
A mixed methods study found that high-performing facilitators in a large-scale quality improvement initiative showed significant impact on clinical outcomes, with 75% or more of their assigned practices demonstrating improvements. The research analyzed data from 162 facilitators supporting 1,630 primary care practices across 12 states.
A large observational study found that moderate coffee consumption, including decaffeinated and ground coffee, was associated with reduced risk of cardiovascular disease and death. The study suggests that mild to moderate intake of coffee can be part of a healthy lifestyle.
Researchers at UVA Health have developed a new magnetic-resonance imaging (MRI) technique to track peripheral artery disease, which affects over 200 million people worldwide. The CEST approach produces comparable results to the current gold standard without requiring specialized equipment.
A scientific review found that cold water swimming can reduce 'bad' body fat and improve insulin sensitivity. However, the health benefits are uncertain due to limited study quality and variability in participant profiles.
Researchers have discovered how a common blood stem cell mutation, DNMT3A R882, alters gene activity and produces abnormal blood cells that increase cancer risk. The study found that the mutant cells produce more red blood cells and platelets, leading to higher cardiovascular disease risks.
A large study of former smokers found that those adhering to evidence-based recommendations for body weight, diet, physical activity, and alcohol intake had a significantly lower risk of death. The study included nearly 160,000 older U.S. adults and showed that better lifestyle habits can reduce mortality risk from various causes.
Women with a history of gestational diabetes are at substantially higher risk of cardiovascular and cerebrovascular diseases, including coronary artery disease, heart attack, and stroke. Continuous monitoring is crucial to mitigate these risks.
A new study finds that consistently losing an hour and a half of sleep per night can negatively impact immune stem cells, leading to increased inflammation and cardiovascular disease. Even after catching up on sleep, the effects of disrupted sleep remain long-lasting.
Research found that people with HIV who also have untreated hepatitis C virus have a higher risk of heart attack as they age. The study analyzed health data from 23,361 people with HIV and found that those co-infected with hepatitis C had a significantly increased risk of heart attack compared to those with HIV alone.
A study by researchers from UTHealth Houston and the University of Miami found that adolescents with severe obesity who underwent bariatric surgery before age 22 lost significant weight and experienced complete remission of comorbidities such as diabetes, asthma, and elevated lipids. The study's results show that these young patients c...
A recent study by the American Heart Association highlights that poorly controlled high blood pressure is a leading cause of cardiovascular emergencies in the US. The study analyzed over 20 million emergency department visits and found that 13% were for essential hypertension, which led to hospital admission less than 3% of the time.
Researchers from the University of Copenhagen have identified a new mechanism in ARVC that could lead to a potential treatment strategy. They found that activating sirtuin-3 can slow down disease progression, and honokiol, a natural product extracted from the tulip tree, has been shown to work similarly.
Researchers analyzed over 6,700 patients treated for blood clots and irregular heart rhythms. Stopping aspirin significantly reduced bleeding complications by 32.3% and prevented one major bleeding event per every 1,000 patients who stopped taking aspirin.
A Brazilian study analyzed risk factors for heart attacks and found that high blood sugar had the most significant impact on mortality. Reducing smoking prevented most deaths from cardiovascular disease, while lowering diabetes incidence could have saved up to 5,000 lives over a decade.
A new study of over half a million people with type 2 diabetes found that smoking and low physical activity significantly increase the risk of premature death. Individuals with type 2 diabetes who develop cancer are more likely to die in seven years if they are smokers or physically inactive.