Researchers at the University of Minnesota Medical School conducted a large clinical trial comparing two commonly prescribed generic drugs, chlorthalidone and hydrochlorothiazide. The study found that both medications were equally effective in preventing cardiovascular disease and non-cancer death, contradicting current clinical guidel...
A new study suggests that reformulating packaged foods in Australia to contain less sodium could save up to 1,700 lives per year. Implementing the World Health Organization's sodium targets may also reduce rates of cardiovascular disease and stomach cancer.
A Harvard T.H. Chan School of Public Health study found that participants following at least one of four healthy eating patterns had a lower risk of premature death and reduced mortality from cardiovascular disease, cancer, and respiratory disease. The study's findings are consistent with the current Dietary Guidelines for America.
A new study from York University sheds light on biological underpinnings of sex differences in obesity-related disease. Female mice grow more new blood vessels to supply fat tissue with oxygen and nutrients, whereas males have a high level of inflammation-associated processes.
Researchers at Goethe University Frankfurt have found that jet engine lubrication oils are a significant source of ultrafine particles. These tiny particles can penetrate deep into the lungs and trigger inflammatory reactions, potentially contributing to cardiovascular diseases.
Researchers at the University of Cincinnati found a link between latent tuberculosis infection and increased inflammation in monocytes, a type of white blood cell. This connection may contribute to a higher risk of cardiovascular disease in individuals with LTBI.
A team of researchers has identified a protein called hemopexin that may help protect the heart from damage caused by anthracycline chemotherapy. Levels of hemopexin in the blood were associated with increased cardiac toxicity, but administering hemopexin prevented the development of cardiac dysfunction in mice.
A Mediterranean diet has been associated with a reduced risk of adverse pregnancy outcomes. The study found a dose-response relationship between the intake of Mediterranean diet and lower risk of such outcomes.
A study of 5,308 participants aged 50-64 found significant correlations between sedentary behavior and low fitness levels. Highly uneven fitness distribution was observed among groups at higher risk, including older adults, foreign-born individuals, and those with poor health and lifestyle habits.
Vascular diseases such as atherosclerosis are associated with the reorganization of blood vessel structure through transdifferentiation. The researchers discovered that endothelial cells can transdifferentiate into smooth muscle cells, driven by HIF1α, and that this process contributes to neointima formation.
A new study found that drinking two or more cups of coffee daily may increase the risk of cardiovascular disease mortality among people with severe hypertension. In contrast, moderate green tea consumption did not show a significant association with increased risk, suggesting potential benefits of polyphenols in reducing mortality.
A study published in Circulation found that walking between 6,000 and 9,000 steps per day significantly lowers the risk of a cardiovascular event in older adults. For those who are least active, even small increases in daily step count can have a substantial impact on heart health.
Researchers found genetic mutations to OAS and RNase L proteins increase inflammatory response in immune cells, leading to MIS-C. This understanding may provide clues to chronic inflammation diseases like Kawasaki disease.
A new study from University of Limerick has found that loneliness and social isolation increase the risk of premature death for individuals with cardiovascular disease. The research, which examined data from around the world, highlights the importance of addressing these factors in the treatment of cardiovascular disease.
Researchers at Memorial Sloan Kettering Cancer Center discovered that common cancer treatments cause long-term damage to heart tissue by activating a key inflammatory signaling pathway. Inhibiting this pathway may reduce the risk of cancer survivors developing heart disease later in life.
Regular follow-up clinic visits with a nephrologist after hospital discharge significantly reduce mortality risk in patients with acute kidney injury (AKI). This study found that such visits, focusing on cardiovascular disease and kidney complications management, lead to lower mortality rates by 29% compared to standard care.
A recent study discovered a link between soluble urokinase plasminogen activator receptor (suPAR) and the development of atherosclerosis, a hardening of arteries that affects over a billion people worldwide. SuPAR was found to cause inflammation in blood vessels, leading to cardiovascular events and increasing risk of heart disease.
The study shows that RXR ensures hematopoietic stem cells remain youthful and fit, reducing the risk of developing myeloproliferative syndromes. The regulatory action of RXR on these cells is essential for maintaining a balanced production of blood cell types throughout life.
A new study found that a machine learning-based blood test can accurately predict an individual's entire diet over 19 food groups, outperforming traditional methods. The test, which uses molecular profiling, also identifies who is more likely to develop diabetes and cardiovascular disease based on each food group.
A large VA clinical trial found that chlorthalidone (CTD) was not superior to hydrochlorothiazide (HCTZ) for preventing cardiovascular disease or non-cancer death. The study enrolled over 13,500 Veterans with high blood pressure and showed no difference between the two drugs in terms of effectiveness.
A new study finds that inadequate pollination leads to a 3-5% loss of fruit, vegetable, and nut production, resulting in 427,000 excess deaths annually from lost healthy food consumption. The health burden is greater in middle- and higher-income countries with high rates of non-communicable diseases.
A new study published in Hypertension suggests that lipoprotein(a) cholesterol may affect the relationship between hypertension and cardiovascular disease risk. The study found that people with high levels of lipoprotein(a) and hypertension had a 24% higher risk of cardiovascular disease compared to those without hypertension.
The latest report tracks global trends in cardiovascular health, revealing high blood pressure, high cholesterol, and air pollution as leading causes of cardiovascular disease worldwide. The study estimates that over 80% of cardiovascular disease is preventable.
A new study published in JAMA Network Open found that patients with depression are less likely to adhere to essential medical therapies following percutaneous coronary intervention (PCI). The study examined over 124,000 patients who underwent PCI and were diagnosed with depression, revealing a significant proportion of individuals with...
A new study found that extreme temperatures are linked to a higher risk of cardiovascular death, particularly heart failure, which was the leading cause of death globally. The research analyzed data from 32 million cardiovascular deaths in 567 cities across 27 countries between 1979 and 2019.
Researchers from Florida Atlantic University have developed a prototype of a novel wearable device that can continuously monitor physiological parameters associated with heart failure in real-time. The device uses sensors embedded in a lightweight belt to track thoracic impedance, electrocardiogram, heart rate, and motion activity, pro...
A global analysis of over 32 million cardiovascular deaths found that extreme temperatures increase the risk of heart failure deaths. People with heart failure are most likely to be negatively impacted by very cold and very hot days.
A new study identifies anti-Müllerian hormone (AMH) as a key factor in regulating cholesterol levels during the menopause transition. High AMH levels are associated with lower HDL-C, or good cholesterol, which may indicate cardiovascular risk despite its traditionally protective effects.
A new American Heart Association scientific statement highlights the potential benefits and risks of complementary and alternative therapies for heart failure. The statement advises healthcare professionals to discuss CAM use with patients, monitor medication interactions, and consider pharmacists' consultations.
A Cedars-Sinai study found that even subtle forms of liver disease directly impact heart health, with elevated FIB-4 scores associated with abnormalities in heart function and vascular dimension. Cardiac MRI scans revealed that nearly 86% of patients had at least one heart abnormality.
Researchers at USC developed a 'heart attack on a chip' device to study heart attacks and test new personalized medicines. The device replicates the effects of an oxygen gradient on cardiac tissue function, shedding light on the mysteries of heart cell communication and change after a heart attack.
A study suggests that visceral fat cells, rather than subcutaneous fat cells, are more susceptible to infection by the COVID-19 virus. This increased susceptibility leads to a higher viral load and production of pro-inflammatory cytokines, which can exacerbate severe disease.
A randomized clinical trial found that two anti-inflammatory strategies reduced disease activity and arterial inflammation in patients with moderate to high rheumatoid arthritis. The treatments had no differences in cardiovascular risk reduction, highlighting the importance of specific clinical trials for this population.
Research highlights importance of long-term screening and healthy lifestyle behaviors in reducing cardiovascular disease risk among young cancer survivors. Factors such as sociodemographic status, income, education, smoking status, and physical activity levels are associated with increased or decreased CVD risk.
A meta-analysis of over 884 studies found that certain micronutrients can benefit cardiovascular health, including omega-3 fatty acids, folic acid, and CoQ10. These supplements have been shown to reduce the risk of cardiovascular disease, stroke, and mortality.
Researchers found that using portable home air purifiers improved markers of cardiovascular health in people with COPD. The study tracked participants' lung and heart health over six months, revealing a 25% increase in heart rate variability among those using active HEPA and carbon filters.
Researchers at University of South Australia have developed a non-contact system to accurately measure systolic and diastolic blood pressure using AI algorithms and a camera. The system achieved 90% accuracy in readings, outperforming existing methods.
A recent study led by the University of Nevada, Reno and the Pan American Health Organization suggests that the adoption of front-of-pack nutrition labeling can help reduce poor-nutrition related non-communicable diseases in the region. Improved FOPNL systems have been associated with improved diet quality and reduced risk of NCDs.
A recent study published in Geriatrics found that age, education, social network, pain, and depression are significant predictors of physical activity in older adults. The findings suggest that modifying these factors through targeted interventions can increase physical activity levels.
A new study found that 1 in 10 women without pre-existing hypertension may develop it up to a year after childbirth, highlighting the need for extended blood pressure monitoring. Mothers at highest risk include those over 35, current or former smokers, and C-section deliveries.
A new PET imaging method is more effective than angiograms in determining the need for coronary stents or bypass surgery, according to UTHealth Houston researchers. The study confirms that PET threshold of severity at which stents and bypass surgery improve survival compared to medical treatment alone.
Researchers developed a deep learning model that uses a single chest X-ray to predict the 10-year risk of death from cardiovascular disease. The model performed similarly to established clinical standards and provided incremental value in predicting major adverse cardiac events.
A new study published in the American Journal of Cardiology found that a healthy diet can reduce the risk of cardiovascular disease by up to 10%. The Dietary Approaches to Stop Hypertension (DASH) diet, which emphasizes whole grains, lean proteins, and fruits and vegetables, showed additional benefits for women and black adults compare...
A lower frequency of adding salt to foods is associated with a reduced risk of heart disease, regardless of lifestyle factors and pre-existing disease. Combining a DASH-style diet with low salt usage further improves heart health.
A new study using artificial intelligence has found that a simple eye test can accurately predict the risk of heart disease. The researchers developed an algorithm that can analyze retinal images to assess cardiovascular health, providing a non-invasive alternative to traditional risk scores.
Researchers found that individuals with persistent asthma have higher levels of inflammation and artery plaque, which may increase heart attack or stroke risk. The study also highlights the importance of addressing risk factors for cardiovascular disease in people with persistent asthma.
A Michigan Medicine study found that Black patients who undergo minimally invasive procedures for clogged arteries are more likely to die or be readmitted to the hospital months after the procedure. Social determinants of health, including community economic well-being and preexisting health conditions, played a significant role in the...
Research findings suggest that skewed X chromosome inactivation may indicate increased risk of developing chronic diseases, including cardiovascular disease and cancer. XCI-skew is a measure of how many cells in a tissue inactivate the same parental X chromosome.
A new survey by the European Federation of Dietitians supports moderate coffee consumption as having clear health benefits, including improved alertness and sports performance. The study involved 585 dietitians from across 26 European countries.
A study found that lower levels of HDL cholesterol increased the risk of heart attacks in white but not Black adults. Higher levels of HDL cholesterol did not provide protective benefits for either group. The research tested long-held assumptions about the role of HDL in cardiovascular health.
Researchers at the University of Houston have developed a protocol to reprogram human heart cells into specialized cells that conduct electricity, enabling rhythmic heartbeat and repair diseased hearts. The discovery could lead to improved cardiac function and new pharmacological therapies for heart diseases.
The American College of Physicians recommends policies to improve healthcare access and quality for incarcerated patients, including adequate funding and timely access to necessary services. The organization also supports treating substance use disorders as an alternative to incarceration.
A new study from the University of South Australia found that eating 30-50 grams of almonds can help people cut back on kilojoules consumed each day. This leads to a reduced energy intake by 300 kilojoules, mostly coming from junk food.
A UCF researcher is studying the potential long-term effects of COVID-19 on people with diabetes, including how it can advance their risk for heart disease and other complications. Dr. Singla believes that COVID-19 can alter a person's genetic makeup, leading to enhanced proliferation of disease.
Inducing a hibernation-like state in mice using Q neuron activation has been shown to protect kidneys from oxygen deprivation and avoid harmful side effects. This technique could lead to new methods of performing heart surgery with reduced organ damage.
A new study from Mount Sinai Hospital finds a strong association between age-related macular degeneration and severe forms of heart disease, including heart failure, heart attacks, and stroke. The study highlights the importance of increased screening for eye disorders to diagnose undetected heart disease.
A study analyzing data from eight European countries found that younger and older mothers, as well as those born abroad or from minority ethnic backgrounds, are at particular risk. The maternal mortality rate is significantly higher in Slovakia and the UK compared to Norway and Denmark, with a fourfold difference.
The USPSTF recommends against routine screening for obstructive sleep apnea (OSA) in asymptomatic adults and those with unrecognized symptoms. OSA is linked to various adverse health outcomes, including cardiovascular disease and cognitive impairment.
A study of 2,400 women found nearly a quarter developed high blood pressure more than six weeks after delivery. The research suggests monitoring during this period could mitigate severe cardiovascular complications.
A study of 11,945 people found that those with type 2 diabetes are more likely to be diagnosed with advanced cancer if the condition is not screened for routinely. Researchers identified a 26% increased risk of metastasis in patients with pre-existing type 2 diabetes.