Add BrightSurf on Google Email

Adversity in childhood is linked to increased risk of heart and blood vessel diseases in early adulthood

A large study found that children who experienced adversity, including serious family illness or death, poverty, neglect, or dysfunctional relationships, are at increased risk of developing cardiovascular disease in early adulthood. The study, published in the European Heart Journal, followed nearly 1.3 million children and found a 60%...

SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·TypeObservational study·DateNov 14, 2022

Bariatric surgery decreases risk of heart disease

A Rutgers study of 86,964 adults with obesity and NAFLD found that bariatric surgery reduced the risk of major cardiovascular events by 49% compared to nonsurgical care. This is significant because heart disease is a leading cause of death in the US, and NAFLD can lead to liver damage and inflammation.

SourceRutgers University·JournalJAMA Network Open·TypeData/statistical analysis·DateNov 14, 2022

Healthy plant-based diets better for the environment than less healthy plant-based diets

A new study found that healthier plant-based dietary patterns had lower cardiovascular disease risk and lower greenhouse gas emissions compared to less healthy plant-based diets. Diets high in refined grains, sugary drinks, and processed meat required more cropland, fertilizer, and irrigation water.

SourceHarvard T.H. Chan School of Public Health·JournalThe Lancet Planetary Health·TypeObservational study·DateNov 10, 2022

Screening for stroke risk can save lives and money

Research conducted at Linköping University found that screening for atrial fibrillation in older people could increase the chance of preventing stroke while saving money for healthcare systems. The study, based on data from the STROKESTOP clinical trial, suggests that screening can be a cost-effective intervention.

SourceLinköping University·JournalEuropean Heart Journal·DateNov 9, 2022

Psychological distress an important, easy-to-measure indicator of cardiovascular risk

A meta-analysis of over 600,000 patients found that psychological distress assessed with brief questionnaires was associated with nearly a 30% greater risk of cardiovascular disease. The screening process can be easy and efficient for healthcare providers without significant psychology training.

SourceBrown University·JournalJournal of Cardiopulmonary Rehabilitation and Prevention·TypeMeta-analysis·DateNov 7, 2022

Specific modifier genes determine the effect of mutations that cause non-compaction cardiomyopathy

Researchers found that the presence of one Mindbomb1 mutation does not always lead to non-compaction cardiomyopathy, but depends on genetic context provided by other gene mutations. The study identified modifier genes contributing to disease severity and diversity in affected individuals.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalCirculation·TypeExperimental study·DateNov 7, 2022

Clinical trial finds novel therapy markedly reduced lipoprotein(a) levels in people with cardiovascular disease

Researchers at Brigham and Women's Hospital found that olpasiran, a small interfering RNA drug, significantly reduces lipoprotein(a) levels in patients with established cardiovascular disease. The treatment was associated with minimal serious side effects apart from injection site reactions.

SourceBrigham and Women's Hospital·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateNov 6, 2022

Getting to the heart of COVID-19 vaccination and its cardiovascular risks

A comprehensive review and meta-analysis found that young adults under 40 have a slightly elevated risk for myocarditis or pericarditis after mRNA COVID-19 vaccination. The analysis analyzed data from over 58 million participants and explored the relationship between COVID-19 vaccine and these rare but dangerous adverse reactions.

SourceElsevier·JournalAmerican Journal of Preventive Medicine·TypeSystematic review·DateNov 1, 2022

Wearable device study in 88,000 people shows the heart health benefits of more intense physical activity

A new study using wearable devices found that moderate-to-vigorous physical activity significantly reduces cardiovascular disease risk, even when total physical activity volume is increased. Increasing the proportion of intense physical activity within overall activity levels has an additional substantial benefit.

SourceUniversity Hospitals of Leicester NHS Trust·JournalEuropean Heart Journal·TypeObservational study·DateOct 27, 2022

Smoking and vaping had overlapping adverse health effects, dual product use may be worse

Two studies found that cigarette smoke and e-cigarette vapor have similar cardiovascular effects due to airway irritation. This irritation can lead to vascular damage and impaired blood vessel function. The research suggests that dual product use may be worse than single product use, highlighting the need for stricter regulations.

SourceAmerican Heart Association·JournalArteriosclerosis Thrombosis and Vascular Biology·DateOct 26, 2022

Drs. Harriette Van Spall and Erica Gunderson to be honored with the Dr. Nanette K. Wenger Research Goes Red® Award

The American Heart Association honored Drs. Harriette Van Spall and Erica Gunderson with the 2022 Dr. Nanette K. Wenger Research Goes Red Award for their groundbreaking study on sex-specific clinical outcomes of heart failure patients. The research found that women experienced improved outcomes after receiving transitional care service...

New genetic research by UMass Amherst advances understanding of internal mechanisms of biological clocks

The study reveals that a genetic mutation can accelerate the body's internal clock, leading to improved adjustment to shift work schedules. The findings have implications for understanding the health consequences of circadian misalignment and developing medical treatments.

SourceUniversity of Massachusetts Amherst·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateOct 20, 2022

Drug discovery method identifies naturally occurring metabolite that converts ‘bad’ fat to ‘good’ fat

A team of scientists at Scripps Research and Calibr discovered a naturally occurring metabolite called myristoylglycine that can convert white fat cells into brown fat cells, potentially treating obesity and related diseases. The breakthrough uses a novel drug discovery method to identify endogenous metabolites with therapeutic potential.

SourceScripps Research Institute·JournalMetabolites·DateOct 13, 2022

Smoking, diabetes and obesity – not preexisting heart disease – bigger risk of COVID-19 death, study finds

A national study found that patients with cardiovascular disease had a higher mortality rate than those without, but this association was largely due to shared risk factors. Myocardial injury was common among critically ill COVID-19 patients and associated with poor outcomes.

SourceMichigan Medicine - University of Michigan·JournalCirculation Cardiovascular Quality and Outcomes·TypeData/statistical analysis·DateOct 12, 2022

Cleveland Clinic researchers identify diabetes drug metformin as potential atrial fibrillation treatment in collaborative research

Researchers found that metformin targeted 30 genes associated with atrial fibrillation, showing direct effects on gene expression for eight. The study suggests metformin may be a promising candidate for treating atrial fibrillation due to its potential to reduce the risk of complications such as stroke and heart failure.

SourceCleveland Clinic·JournalCell Reports Medicine·DateOct 11, 2022