Articles tagged with Cardiovascular Disease
Researchers found smokers have significantly lower A1AT levels, which may reduce cardiac tissue protection during a heart attack. No difference was detected in hypertensive and non-hypertensive individuals.
Researchers at the University of Eastern Finland have developed a novel nuclear microRNA, miR-466c, that regulates vascular endothelial growth factor A (VEGFA) expression in response to hypoxia. The drug has commercial relevance for treating ischemic cardiovascular disease by increasing VEGFA levels.
A study by Alisa Auer and Petra Wirtz found that men with essential hypertension are more likely to recognize angry expressions when looking at others' faces. This 'anger recognition bias' contributes to increased blood pressure over time if someone experiences high levels of anger.
The University of Minnesota Medical School has been awarded two $3.25 million and $3.25 million NIH grants to study cardiovascular health among a diverse population of school-aged children. The research, led by Jerica Berge, will address social and structural determinants of health in primary care settings.
A new analysis reveals that salt substitutes are not only effective in reducing stroke risk but also cost-saving, with costs outweighing the cost of the intervention. The study found a 14% reduction in stroke risk and 13% reduction in strokes and heart attacks combined.
A large prospective study found a positive association between higher avocado consumption and lower cardiovascular events. Avocados contain healthy fats and other favorable components that support good cardiovascular health.
A study identifies new biomarkers that predict the presence of subclinical atherosclerosis, providing a non-invasive way to detect cardiovascular disease. The research team analyzed blood plasma samples and validated three proteins as biomarkers, improving the prediction of cardiovascular risk.
Researchers at UConn Health found that deleting TRPM2 from macrophages in mice reduced atherosclerosis by inhibiting the TRPM2–CD36 inflammatory axis. This approach prevented foamy macrophages and alleviated inflammation in arteries.
A randomized controlled study found that lack of sufficient sleep increased calorie intake and visceral fat area by 9% and 11%, respectively. The study suggests that inadequate sleep is a previously unrecognized trigger for visceral fat deposition, potentially contributing to obesity and metabolic diseases.
A large study published in JAMA Network Open found no evidence that light alcohol consumption provides heart-related health benefits, instead suggesting lifestyle factors common among moderate drinkers contribute to the observed benefit. The study linked high-risk cardiovascular disease across all levels of alcohol intake.
A new study by the American College of Cardiology reveals that exercise nearly doubles the cardiovascular benefit for individuals with depression or anxiety. Regular physical activity can reduce the risk of major adverse cardiovascular events by up to 22% in those with anxiety and depression, compared to 10% for those without these con...
A study finds that extreme heat is associated with a significant increase in cardiovascular mortality, particularly among men and non-Hispanic Black adults. The researchers analyzed data from over 3,100 counties in the US and found that each additional day of extreme heat was linked to an average of 600-700 additional deaths per year.
A recent study found that approximately 1 in 3 heart attack survivors experience significant mental decline in the days and months following their heart attack. Cognitive deficits can impact quality of life and treatment adherence, emphasizing the need for cardiologists to monitor patients regularly.
A study found that living near high levels of transportation noise increases the risk of heart attack by 72%, with 5% of hospitalizations attributable to elevated noise levels. Noise exposure can cause chronic stress, sleep disturbances, and emotional distress, leading to cardiovascular health issues.
A clinical trial found that daily cranberry consumption improved flow-mediated dilation, a biomarker of cardiovascular disease risk, in healthy men. Cranberries' unique proanthocyanidins may play an important role in preventing cardiovascular disease.
A comprehensive literature review found that consuming plant-based alpha-linolenic acid (ALA) rich in walnuts and flaxseeds can lower cardiovascular disease risk by 10% and fatal coronary heart disease risk by 20%. ALA may also benefit heart health when combined with other omega-3s.
Researchers at CNIC discover that bone marrow activation is an early event in the development of atherosclerosis, leading to inflammation and plaque formation. The study identifies metabolic syndrome as a key trigger for this process.
Researchers identified three NAFLD subtypes with unique lipidomic profiles and varying cardiovascular disease risk. Subtype A shows a lower CVD risk profile, differing from other subtypes, which may explain variation in hepatic versus cardiovascular outcomes.
A randomized, placebo-controlled trial found that a cocoa flavanol supplement reduced cardiovascular death by 27% and total cardiovascular events by 10%. The study also showed no significant effect on cancer risk. Further investigation is warranted to understand the effects of cocoa flavanols on cardiovascular health.
Researchers found that post-COVID patients displayed altered autonomic nervous system functioning, with increased sympathetic activity and decreased parasympathetic activity. Obesity and physical inactivity were key factors contributing to these changes.
New research suggests that routine mammograms can provide key insights into a woman's risk of cardiovascular disease. The study found that detection of breast arterial calcifications on mammograms was associated with a higher risk of heart disease and stroke in postmenopausal women.
A new retrospective cohort study analyzed data from over 4.5 million adult cancer patients, revealing a significantly higher risk of cardiovascular mortality and events following a new cancer diagnosis. The study highlights the need for a collaborative approach to healthcare for cancer patients and survivors.
Researchers at the University of Ottawa developed a spray-on technology using customized nanogold and peptides that can restore heart function and electrical conductivity in damaged hearts. The therapy showed promising results in lab mice, with no off-target organ infiltration by tiny gold particles.
A study of insurance claims data found that state laws governing opioid prescribing had a negligible effect on opioid prescribing trends. The authors suggest that shifting clinical guidelines, professional norms, or other factors may be driving the decline in opioid prescribing. In contrast, a post-hoc analysis of an ASPREE trial found...
A new study published in JAMA Internal Medicine found that the link between high cholesterol and heart disease may not be as strong as previously thought. The research suggests that statins may have a modest benefit for some individuals, but this benefit varies depending on personal risk factors.
Researchers found that impaired kidney function is preferentially associated with cardioembolic stroke in a large cohort of patients. Low filtration rates and high urine protein levels predicted increased risk of cardioembolic stroke, disability, and mortality.
The International Lipid Expert Panel recommends a step-by-step approach to diagnosing and managing muscle symptoms caused by statins. The 'nocebo/drucebo' effect, where patients experience side effects due to expectation, affects up to 70% of diagnosed statin intolerance cases.
A new study found that consuming a balanced diet with proteins from various different sources may help prevent the development of high blood pressure. The analysis involved nearly 12,200 adults in China and found an association between protein variety score and reduced risk of new-onset hypertension.
Researchers found that elevated blood levels of two cardiovascular markers are associated with higher risks of cardiovascular problems in psoriatic disease patients. The study suggests a potential clinical tool for assessing heart health, but ordering tests is not recommended for asymptomatic patients.
A landmark study published in JAMA reveals that hurricanes and tropical cyclones in the US are associated with increased deaths from various causes, including injuries, infectious diseases, and cardiovascular conditions. The study analyzed 33.6 million death records and found a significant increase in mortality rates after tropical cyc...
A new analysis by University of Copenhagen researchers found that a Nordic diet has positive health benefits regardless of weight loss. The diet's unique fat composition, high in omega-3 and omega-6 unsaturated fats, plays a significant role in lowering blood sugar and cholesterol levels.
A clinical decision support system was found to lower cardiovascular risk for patients with severe mental illness by providing individualized informational handouts and treatment recommendations. The study suggests that such systems may result in positive impacts on long-term cardiovascular health.
A recent study published in Applied In Vitro Toxicology found that tobacco-free nicotine pouches exhibit reduced levels of toxicants and biological activity compared to combustible cigarette smoke. The products, manufactured by Imperial Brands, showed substantially reduced genotoxicity and cytotoxicity in three toxicological assays.
Researchers at the Salk Institute successfully reversed aging signs in middle-aged and elderly mice using a cellular rejuvenation approach. The treatment, which involves reprogramming cells with four specific molecules, restored youthful epigenetic patterns and improved tissue function without increasing cancer risk.
Researchers have identified a crucial nuclear transport mechanism essential for organ growth and development, involving the protein YAP. The study shows that YAP interacts with importin-7 to control its nuclear entry, regulating cell and tissue growth, and potentially targeting diseases such as atherosclerosis and cancer.
A new study reveals that simultaneous measurement of dozens of types of fats in the blood can predict the risk of developing type 2 diabetes and cardiovascular disease years in advance. The researchers found that individuals with a certain lipid profile are at increased risk, while those with a different profile have lower risk. This d...
A pooled data analysis found that between 30 and 60 minutes of muscle strengthening activity per week is associated with a 10-17% lower risk of death from any cause. The J-shaped curve showed no conclusive evidence that more than an hour of this activity reduces the risk further.
A new collection of scientific articles reviews the past decade of research on women's cardiovascular health, identifying key differences between men and women. The studies highlight critical gaps in current knowledge and emphasize the need for a more tailored approach to diagnosing and treating heart disease and stroke risk in women.
A large study found a significant link between salt-containing paracetamol and an increased risk of heart attacks, stroke, and death. Patients with high blood pressure who took sodium-containing paracetamol had a higher risk of cardiovascular disease and death compared to those taking non-sodium-containing paracetamol.
Research found that women who experienced sexual violence were more likely to develop high blood pressure over a seven-year period. Women who experienced both sexual assault and workplace harassment had the highest risk of developing high blood pressure.
Researchers discovered specific ceramides in the blood are associated with unfavorable levels of diabetes-related compounds, linking unhealthy diets to increased risk. Ceramide profiling may enable more precise dietary approaches for preventing cardiometabolic diseases.
Researchers at University of Missouri found a long-term association between adolescent psychological well-being and adult cardiovascular disease risk. People who are more optimistic in their youth can lower their chances for heart disease as adults.
A study reveals that changes in gut microbiota and metabolome are associated with cardiovascular disease development, particularly coronary heart disease. The research found that alterations in the gut microbiome occur long before the onset of heart disease, suggesting a potential role for the microbiome in its early pathogenesis.
A new study from the University of Helsinki found that providing individuals with their personal genetic risk for cardiovascular disease motivates them to take better care of their health. The interactive web-tool KardioKompassi helped participants understand their risk and make lifestyle changes.
A large-scale study of 400,000 adults in the UK Biobank found no evidence that eating vegetables reduces the risk of cardiovascular disease. The researchers controlled for various confounding factors and found that any apparent effect was largely due to residual confounding.
Researchers have made a significant breakthrough in predicting heart attacks and strokes by developing a non-invasive method using super-resolution ultrasound imaging. The technology aims to detect high-risk atherosclerotic plaques that are prone to rupture, allowing doctors to prescribe life-saving interventions.
A new 10-year analysis shows that only half of individuals with high blood pressure, high cholesterol, or obesity receive lifestyle support from their GPs. Lifestyle interventions can significantly reduce the risk of cardiovascular disease.
A Swedish registry study found no increase in endocarditis cases among high-risk individuals since the removal of prophylactic antibiotics in dentistry. The study monitored over 76,000 high-risk individuals and 396,000 low-risk individuals from 2008 to 2018.
Only 1.9% of Chinese children and adolescents exhibit ideal cardiovascular health status, with socioeconomic factors impacting behavior. Researchers recommend strategies like household smoking control and physical activity promotion to improve cardiovascular health in young generations.
A new study found that statin intolerance is over-estimated, affecting only 6-10% of patients worldwide. Researchers identified risk factors for statin intolerance, including age, sex, ethnicity, and medical conditions.
A study of 3099 older Italians found that increasing physical activity levels between 65-75 years old can lower cardiovascular disease risks in late old age. Maintaining an active lifestyle over time was associated with a 52% lower risk of cardiovascular disease among men.
A study by Washington State University found that social support can mitigate the risk of heart disease and death in older American Indians. Higher rates of depression symptoms, poor quality of life, and social isolation were linked to increased mortality, but instrumental social support reversed this effect.
Researchers at Universidad Carlos III de Madrid developed a computer vision system to analyze cells in microscopy videos, allowing for automatic characterization of cell behavior. The system enables faster analysis of thousands of cells compared to traditional methods, which typically involve manual segmentation and tracking.
The American Roentgen Ray Society has awarded two 2022 ARRS Scholarships to Sean Woolen and Bradley Allen, providing a total of $180,000 in funding for their radiological research projects. The scholarships aim to advance emerging scholars and prepare them for leadership positions.
A new study finds that women with a history of gestational diabetes are at greater risk for a range of cardiovascular conditions, including coronary artery disease and heart failure. The research, which analyzed data from 219,330 women, suggests that preventative measures during pregnancy may help prevent cardiovascular disease later i...
The University of South Florida has received a five-year, $1.35 million NIH institutional grant to train scientists in vascular inflammation and injury research. The grant will support the comprehensive training of pre- and postdoctoral scientists focused on this emerging area of research.
Researchers found that young adults with cannabis use disorder are more likely to experience recurrent strokes compared to those without the condition. The study suggests that chronic marijuana use may impair blood vessel function and increase the risk of future strokes.
A study examining national data of adults aged 60 and older found that smoking is strongly linked to poor brain health, independent of other medical conditions. Smoking was associated with lower cognitive test scores in this population.
New research reveals that one in three US stroke survivors experience food insecurity, which can exacerbate cardiovascular disease and stroke risk. Healthcare professionals can play a crucial role in addressing food insecurity by engaging with patients and providing support or resources.
A new scoring system using data from the American Heart Association's COVID-19 Registry predicted the risk of stroke among adults hospitalized with COVID-19. The study found that six clinical factors, including age, medical conditions, and vital signs, helped identify patients at increased risk of stroke.