Researchers have confirmed a link between Trichomonas vaginalis and an increased risk of prostate cancer. The study found that men infected with T. vaginalis were more likely to develop extraprostatic prostate cancer and cancer that is likely to progress to bony metastases or prostate cancer-specific death.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateSep 9, 2009
Researchers identified Hexokinase 2 as a key player in glucose metabolism and cell survival for breast cancer patients with brain metastases. Patients with high levels of Hexokinase 2 expression in their brain metastasis had significantly lower median survival rates compared to those with lower expression.
SourceAmerican Association for Cancer Research·JournalMolecular Cancer Research·DateSep 1, 2009
Researchers found that Six1 protein is central to tumor development in breast cancer, linked to EMT, stem/progenitor cells, and poor prognosis. Overexpression of Six1 also enhanced ability to metastasize, indicating its role as a key player in aggressive breast cancer.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateAug 24, 2009
Researchers at Albert Einstein College of Medicine have identified a distinct population of macrophages that may promote metastatic cancer growth. The study suggests that targeting these cells could inhibit tumor growth and potentially reduce cancer mortality.
SourceAlbert Einstein College of Medicine·JournalPLOS ONE·DateAug 10, 2009
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
New commentary published in JNCI Journal of the National Cancer Institute discusses treatment options for metastatic breast cancer. The European School of Oncology Metastatic Breast Cancer Task Force recommends sequential chemotherapy with a single agent for patients without rapid progression or life-threatening metastasis.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateAug 5, 2009
A study by Hoag Memorial Hospital Presbyterian found that patient-specific cancer vaccines derived from patients' own cells resulted in impressive long-term survival rates. The vaccine was well-tolerated, and eight patients experienced remarkable progression-free survival despite having widely metastatic disease.
SourceHoag Memorial Hospital Presbyterian·JournalCancer Biotherapy and Radiopharmaceuticals·DateJul 28, 2009
A team of researchers at the University of Chicago has designed a computer program that uses artificial intelligence to analyze ultrasound images and predict whether a woman's breast cancer has metastasized. The pilot study, which analyzed 50 women with suspected breast cancer, found that the AI tool accurately identified 20 cases of m...
Research found that smoking increases the likelihood of pancreatic ductal adenocarcinoma becoming metastatic, with osteopontin isoform OPNc playing a key role. High levels of OPNc were detected in 87% of invasive PDA lesions from smokers, correlating with nicotine exposure.
SourceThomas Jefferson University·JournalSurgery·DateJul 27, 2009
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Two matrix metalloproteinase (MMP) proteins contribute to bone metastasis in advanced breast cancer by degrading extracellular matrix and stimulating osteoclast activity. This discovery supports therapeutic targeting of MMP1 and ADAMTS1, potentially mitigating bone complications in advanced metastatic breast cancers.
SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateJul 16, 2009
A study found sunitinib to be safe and well-tolerated in patients with brain metastases, poor performance status, and elderly age groups. Median progression-free and overall survival were 10.9 and 18.4 months respectively.
SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateJul 15, 2009
A new study led by Memorial Sloan-Kettering Cancer Center researchers identifies the genetic function that enables breast cancer cells to survive and spread in the bone marrow. The findings support the development of therapies targeting this survival capacity, which could prevent metastasis and improve patient outcomes.
SourceMemorial Sloan Kettering Cancer Center·JournalCancer Cell·DateJul 6, 2009
Researchers have identified key signals supporting long-term survival of breast cancer cells after they spread to the bone marrow. The study found that activity of a cancer-related enzyme called Src is associated with late-onset bone metastasis and promotes cell survival.
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Lung cancer's rapid spread is linked to a hyperactive WNT cell-signaling pathway, enabling aggressive tumor growth and poor clinical outcomes. The study identifies two genes activated by WNT that enhance invasion and reinitiation of tumor growth in other organs.
SourceMemorial Sloan Kettering Cancer Center·JournalCell·DateJul 2, 2009
A new three-way measurement method has been developed to predict disease metastasis in prostate cancer, combining PSA doubling time, Gleason score, and interval between surgery and detectable PSA levels. This improved prediction method may help determine which patients benefit from additional therapy after surgery.
Researchers at Max Delbrück Center for Molecular Medicine have identified 115 genes associated with metastatic potential in colorectal cancer. The study found that BAMBI gene is more active in metastatic tumors, promoting metastasis formation through key signaling pathways.
SourceHelmholtz Association·JournalGASTROENTEROLOGY·DateJul 1, 2009
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A €12 million European Union-funded study led by the University of Manchester aims to tackle tumour hypoxia, a critical factor hindering effective cancer treatment. Researchers will investigate how hypoxia affects cell behavior and develop targeted therapies to improve patient outcomes.
Researchers at Whitehead Institute for Biomedical Research discovered a microRNA, miR-31, that inversely correlates with metastasis in breast cancer. Increasing miR-31 levels can help predict patient prognoses and potentially aid in the development of targeted therapies.
SourceWhitehead Institute for Biomedical Research·JournalCell·DateJun 15, 2009
The presence of multiple portal vein invasion (PVI) is a significantly poor prognostic factor for hepatocellular carcinoma. Anatomical resection is recommended for patients with HCC and PVI-M, while non-anatomical resection may lead to poorer disease-free survival.
SourceWorld Journal of Gastroenterology·JournalWorld Journal of Gastroenterology·DateJun 12, 2009
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A study published in World Journal of Gastroenterology found that patients with extrahepatic disease, high carcinoembriogenic antigen levels, or multiple nodules have poorer survival rates. Despite this, advances in surgical technique and complementary treatments are increasing the number of patients benefiting from curative treatment.
SourceWorld Journal of Gastroenterology·JournalWorld Journal of Gastroenterology·DateJun 12, 2009
A team of scientists at The University of Texas M. D. Anderson Cancer Center has identified four new targets for breast cancer treatment, including three lysophosphatidic acid receptors and the enzyme autotaxin. These targets are found to be abnormally expressed in many types of cancer and have been shown to cause cancer.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalCancer Cell·DateJun 10, 2009
A new study has found that autoantibodies are not strongly associated with improved outcomes in melanoma patients treated with interferon. The CAPRA score was accurate in predicting bone metastasis, prostate cancer-specific mortality, and all-cause mortality at diagnosis of localized prostate cancer.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateJun 9, 2009
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers uncover molecular mechanism that enables tumor cells to attract new blood vessels continuously in the brain, even when oxygen is still abundant. The discovery could provide a basis for therapies targeting activated integrin alpha-vbeta3 to inhibit metastatic brain disease.
SourceScripps Research Institute·JournalProceedings of the National Academy of Sciences·DateJun 8, 2009
A national RTOG study found that prophylactic cranial irradiation (PCI) significantly decreased the incidence of brain metastases during the first year post-treatment. Patients who received PCI were two and one-half times less likely to develop brain metastasis than those who did not.
Researchers at M.D. Anderson Cancer Center found a significant increase in median overall survival from 8 to 30 months for patients with advanced disease, and a projected five-year survival rate of over 30 percent. The study attributes the improvements to better surgical interventions and new chemotherapeutic agents.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalJournal of Clinical Oncology·DateMay 26, 2009
LSUHSC researchers discovered that excessive IQGAP1 production weakens cell-to-cell contacts, promoting cell migration and invasion. The study provides insights into the prolonged activated state of Cdc42, a key protein involved in cancer spread.
SourceLouisiana State University Health Sciences Center·JournalJournal of Biological Chemistry·DateMay 21, 2009
Researchers at the Mayo Clinic have found a triple drug combination to be an effective and tolerable option for treating metastatic HER2+ breast cancer. The regimen, which combines capecitabine, vinorelbine, and trastuzumab, has shown promising results in reducing tumor size and improving survival rates compared to traditional treatments.
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers found that the gene ZBP1 is silenced in metastasizing breast cancer cells due to a methyl group attachment, leading to increased cell migration and proliferation. The study suggests potential drug targets for preventing metastasis and may help predict breast tumor outcomes by identifying signs of ZBP1 silencing.
SourceAlbert Einstein College of Medicine·JournalJournal of Cell Science·DateMay 12, 2009
Researchers have identified a new prognostic factor in breast cancer patients, predicting early disease recurrence, metastasis, and patient survival. The absence of caveolin-1 in the stroma is strongly associated with more aggressive disease and reduced progression-free survival.
SourceThomas Jefferson University·JournalAmerican Journal Of Pathology·DateMay 6, 2009
Research at Memorial Sloan Kettering Cancer Center identifies three genes mediating breast cancer's spread to the brain. COX2 and HB-EGF prime cells for entrance, while ST6GALNAC5 enables passage through the blood-brain barrier.
SourceMemorial Sloan Kettering Cancer Center·JournalNature·DateMay 6, 2009
Researchers are developing a strategic approach to studying metastasis, targeting the molecular and cellular players that mediate changes at future sites of metastasis. This could lead to new cancer treatments that target each step along the metastatic pathway.
SourceNewYork-Presbyterian·JournalNature Reviews Cancer·DateMay 1, 2009
Notch1 contributes to lung fibrosis by increasing myofibroblasts, while SOCS-1 inhibits prostate cancer growth. TIP30 prevents lung cancer metastasis, and SPARC accelerates kidney disease progression. These findings highlight potential new therapeutic targets.
SourceAmerican Journal of Pathology·JournalAmerican Journal Of Pathology·DateApr 24, 2009
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Innate Therapeutics' novel microparticle-based immune response modifier MIS416 significantly inhibited tumor growth and metastasis in lung and breast cancers. Administered as an adjunct to localized tumor irradiation, MIS416 demonstrated synergistic activity against recurrent lung tumors.
Researchers found that brain metastases subvert astrocytes, tricking them into protecting tumors and resisting chemotherapy. Surgery is effective when tumor removal is done intact, reducing the risk of cancer spreading to the spinal fluid.
SourceUniversity of Texas M. D. Anderson Cancer Center·DateApr 19, 2009
Researchers at Johns Hopkins Medicine tracked how prostate cancer began in 33 men, finding a set of genetic defects in a single cell that differ for each person's cancer. The study suggests that common genetic patterns across metastatic sites indicate a single cell source.
SourceJohns Hopkins Medicine·JournalNature Medicine·DateApr 17, 2009
Scientists at Heidelberg University Hospital have identified a previously unknown protein called SCAI that inhibits the movement and spread of tumor cells. The study suggests that SCAI could be an interesting starting point for research into new mechanisms for fighting cancer.
SourceHeidelberg University Hospital·JournalNature Cell Biology·DateApr 8, 2009
Researchers at Mayo Clinic have discovered the molecular interplay that enables invasive tumor cells to move and invade other parts of the body. By manipulating this process, they hope to develop treatments to stop cancer from spreading.
SourceMayo Clinic·JournalNature Cell Biology·DateMar 29, 2009
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers identify TMEM density as key to predicting distant organ metastasis in breast cancer. The new marker could enable custom-tailored therapies and prevent over- or under-treatment.
SourceNewYork-Presbyterian·JournalClinical Cancer Research·DateMar 27, 2009
The University of Texas M. D. Anderson Cancer Center has launched a new graduate program focusing on understanding and attacking cancer metastasis. The program, supported by a highly competitive grant from the University of Texas System, aims to improve basic understanding of cancer spread mechanisms.
SourceUniversity of Texas M. D. Anderson Cancer Center·DateMar 26, 2009
Researchers at UVA Health System found that SRC gene promotes growth suppression in bladder cancer, contradicting its role in most cancers. The study suggests caution when using targeted therapeutic agents that inhibit SRC in bladder cancer treatment.
SourceUniversity of Virginia Health System·JournalProceedings of the National Academy of Sciences·DateMar 25, 2009
A new test for metastasis could help doctors precisely identify which patients should receive aggressive therapy, sparing those at low risk from unnecessary treatment. The test detects the presence of a tumor microenvironment that predicts breast cancer spread.
SourceAlbert Einstein College of Medicine·JournalClinical Cancer Research·DateMar 24, 2009
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers propose a new model explaining how cancer cells grow and spread, attributing inefficiency to pressure differences between tumor cells and host tissues. Understanding this process is crucial for developing effective treatments for metastatic cancer.
Researchers have identified a master protein that maintains epithelial cell normality and prevents cancer cells from metastasizing. The Epithelial Splicing Regulatory Protein (ESRP) plays a crucial role in regulating gene splicing, and its dysregulation can lead to cancer cell migration and tissue fibrosis.
SourceUniversity of Pennsylvania School of Medicine·JournalMolecular Cell·DateMar 16, 2009
Researchers created a mouse model of melanoma that replicates the earliest stages of skin cancer in humans. Testing two drug therapies caused a statistically significant regression in cancer cell development, offering hope for new treatment approaches.
SourceUniversity of California - San Francisco·JournalNature Genetics·DateMar 12, 2009
Osteoplasty provides immediate and substantial pain relief for metastatic bone disease patients, often referred to as the 'Lazarus effect'. The procedure involves injecting bone cement into weakened bones, improving quality of life and allowing patients to resume daily activities.
SourceSociety of Interventional Radiology·JournalJournal of Vascular and Interventional Radiology·DateMar 9, 2009
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
A new study found that angiogenesis inhibitors, which starve tumors of their blood supply, can sometimes promote more invasive cancer growth and increase the incidence of metastases. Researchers call for further studies to determine if the drugs affect tumors in patients as they do in mouse models.
SourceUniversity of California - San Francisco·JournalCancer Cell·DateMar 2, 2009
Researchers have precisely measured the impact of fat on cancer spread, finding that excessive dietary fat causes a significant increase in metastasizing tumor cells. The study used imaging and cell-counting tools to document changes in cancer cell membranes and count lipid-rich tumor cells in mice fed high-fat diets.
Researchers found that oxaliplatin combined with capecitabine provided a safe, well-tolerated, and effective treatment for patients with metastatic esophageal squamous cell cancer. The combination showed significant clinical benefits, including partial responses in 43.8% of patients and a median overall survival of 10.0 months.
SourceWorld Journal of Gastroenterology·JournalWorld Journal of Gastroenterology·DateFeb 21, 2009
The study investigates the anti-apoptotic effects of Astragalus saponin extract on human peritoneal mesothelial cells during peritoneal gastric cancer metastasis. The results show that gastric cancer cell supernatant induces apoptosis in mesothelial cells, while Astragalus injection can partly suppress this effect and regulate the expr...
SourceWorld Journal of Gastroenterology·JournalWorld Journal of Gastroenterology·DateFeb 17, 2009
Researchers at Thomas Jefferson University found a biomarker, guanylyl cyclase 2C (GUCY2C), that predicts disease recurrence in colorectal cancer. The study revealed that 87.5% of patients had positive GUCY2C expression and 20.9% developed recurrent disease.
SourceThomas Jefferson University·JournalJAMA·DateFeb 17, 2009
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers identified guanylyl cyclase C as a molecular marker for metastatic colorectal cancer that can detect occult metastases in lymph nodes, improving risk stratification. About 13% of patients with pN0 colorectal cancer were found to be free of tumor cells, while 87% had results suggesting occult metastases.
Researchers at UC San Diego are developing new diagnostic tools to detect early-stage cancers using advanced imaging technologies. They aim to characterize tumor aggressiveness and monitor chemotherapy effectiveness, enabling more effective treatment decisions.
Researchers found that microRNA 182 is over-expressed in metastatic melanoma cell lines and tissues, leading to increased invasive capacity and metastatic potential. Inhibiting miRNA 182 may be an effective therapeutic strategy for metastatic melanoma.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalProceedings of the National Academy of Sciences·DateFeb 9, 2009
A new study identifies Capn4 as a key molecule associated with liver cancer recurrence and metastasis after liver transplantation. The findings suggest that Capn4 expression is correlated with clinical outcomes and could be used as a prognostic marker for diagnosis.
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers at Tel Aviv University have refined breast cancer identification using a combination of MRI and ultrasound, allowing for earlier detection and personalized treatment. The new approach measures metabolism rates of cancer cells, helping determine which tumors will metastasize and how they should be treated.
SourceAmerican Friends of Tel Aviv University·JournalCancer Research·DateJan 26, 2009
Researchers investigate thalidomide for biochemical recurrence and adjuvant radiotherapy for improved survival, reducing metastases risk by 29%. Both treatment options show promise for patients with biochemically recurrent prostate cancer after surgery.
SourceElsevier Health Sciences·JournalThe Journal of Urology·DateJan 22, 2009
A team of scientists at Princeton University has identified a long-sought gene, Metadherin, that is responsible for the aggressive behavior of poor-prognosis tumors and makes them resistant to chemotherapy. The discovery paves the way for new drugs to inhibit the gene's diabolical actions and may have significant health implications.
SourcePrinceton University·JournalCancer Cell·DateJan 5, 2009
Researchers discovered abnormally high copy numbers of chromosomal region 8q22 in more than 30% of breast cancers, associated with shorter survival times. The metadherin gene (MTDH) was found to play a dual role in cancer metastasis and resistance to chemotherapy.
Researchers at Stanford University School of Medicine have discovered that metastatic cancer cells use a protein called lysyl oxidase (LOX) to target specific organs. By blocking LOX expression, the cells' migration and invasion can be prevented, offering a potential new approach to treating human disease.
SourceStanford Medicine·JournalCancer Cell·DateJan 5, 2009
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A research team at UC San Diego has identified a protein called versican that enhances metastasis by stimulating inflammatory cells. Versican is found in low amounts in normal lung epithelial cells but is upregulated in aggressive lung tumors, supporting the growth and spread of cancer.
SourceUniversity of California - San Diego·JournalNature·DateDec 31, 2008
Researchers at Tel Aviv University discovered that transfusions of 'young' blood –– blood stored for less than 9 days –– increased the odds of survival in animals with leukemia and breast cancer. Fresh blood may be a game-changer in cancer treatment, potentially improving survival rates.
SourceAmerican Friends of Tel Aviv University·JournalAnesthesiology·DateDec 30, 2008