Articles tagged with Myocardial Infarction
A new study identified a mechanism behind cardiovascular inflammation after a heart attack and developed a potential strategy to suppress it. The therapy targets molecules that attract immune cells to atherosclerotic plaques, reducing the risk of another heart attack and improving heart function.
A large UK study found that married people are 14% less likely to die after a heart attack and spend two fewer days in hospital. The study suggests that physical and emotional support from a spouse can improve survival rates.
Researchers from Emory University School of Medicine have discovered that chymase inhibitors could extend cell survival after a heart attack. The study found that suppressing chymase activity can prevent late death of heart muscle cells, which occurs several days after blood flow is restored.
A digital health intervention using email and text messages aimed at improving diet and physical activity had no effect on reducing heart attack risk among a South Asian population. The study found that knowledge of genetic risk was not a motivator for behavior change.
Researchers discovered the Oct4 gene plays a critical protective role in preventing heart attacks and strokes by stabilizing atherosclerotic plaques. Manipulating its expression may help block age-related decline in the body's ability to carry out repairs and heal wounds.
According to new research, nearly half of all heart attacks are 'silent', with symptoms appearing so mild that they are barely noticed. Silent heart attacks increase the risk of dying from heart disease and other causes, and can be as deadly as those with classic symptoms.
Untreated obstructive sleep apnea (OSA) is associated with a significant increase in major adverse cardiac and cerebrovascular events, including cardiovascular death, heart attack, stroke, and unplanned revascularization. Patients with OSA have a 1.57 times higher risk of these events compared to those without OSA.
A new analysis suggests that the moderate effect of calcium and vitamin D on fracture prevention is not large enough to outweigh the potential increased risk of cardiovascular disease. For 65-year-old women at low risk of bone fracture, the risks may outweigh the benefits.
Researchers at the University of Copenhagen have identified a new gene linked to familial hypercholesterolemia, a genetic disorder causing very high blood cholesterol. High levels of lipoprotein(a) in the blood increase heart attack risk by five times.
A new study published in the New England Journal of Medicine found that ticagrelor, a commonly used antiplatelet medication, did not significantly reduce stroke risk in patients with transient ischemic attacks or minor strokes. The study suggests that combination therapies may be needed to better prevent strokes in this vulnerable pati...
A study by Ken Suzuki and team found that M2 macrophages play a crucial role in repairing damaged myocardial tissue after a heart attack. Supplementing with these cells or using the cytokine IL-4 can restore repair capabilities and potentially reduce the risk of cardiac rupture.
A Mediterranean diet high in fruit, vegetables, and unrefined foods is associated with a lower risk of heart attack and stroke in people with existing heart disease. The study found that eating more healthy foods was more important than avoiding unhealthy foods.
A recent study by Dr. Barbro Kjellström found that heart attack patients are more likely to be depressed, with 14% experiencing symptoms compared to 7% of control group members. However, antidepressants were prescribed less frequently among heart attack patients with depression, at just 16%, compared to 42% of control group members.
Researchers analyzed previously unpublished data from a large controlled trial and found that using vegetable oils high in linoleic acid may not decrease the risk of heart disease. In contrast, using butter did lower cholesterol levels without affecting heart attacks or deaths.
A 7-year study of half a million Chinese adults found that eating fresh fruit daily was associated with reduced cardiovascular mortality, with strong associations seen in both men and women. The findings suggest that widespread consumption of fresh fruit could prevent hundreds of thousands of cardiovascular deaths annually.
The largest losmapimod study failed to show improvements in cardiovascular death and events, but suggests potential benefits for patients with ST-segment elevation myocardial infarction. The drug's developer plans further studies to validate these findings.
Losmapimod, a p38 MAPK inhibitor, failed to show cardiovascular benefits in patients hospitalized with acute MI. The trial found no reduction in recurrent major adverse cardiovascular events or all-cause mortality among patients treated with losmapimod compared to placebo.
A new study from Intermountain Medical Center Heart Institute shows that testosterone supplementation reduced major adverse cardiovascular events in elderly men with low testosterone levels and pre-existing coronary artery disease. The study found that patients receiving testosterone therapy had a lower risk of heart attacks, strokes, ...
Researchers found that intravenous beta blockers before angioplasty in STEMI patients did not reduce heart attack severity or improve blood flow, according to the EARLY-BAMI trial. The study showed a slight decrease in ventricular arrhythmias but no significant differences in other endpoints.
A large clinical trial found that ischemic postconditioning did not reduce death from any cause or hospitalization for heart failure in STEMI patients, but improved left ventricular ejection fraction in a specific subgroup.
Patients who received a physician discussion using Chest Pain Choice increased their knowledge about their risk and options, answering 53% of questions correctly. The study also found that patients who used the tool were more likely to recommend discussing their care with their physicians, 68.9% compared to 61.2%.
The DANAMI-3-DEFER trial found that delayed stent implantation in STEMI patients did not reduce death from any cause, hospitalization for heart failure, or subsequent heart attacks. The study's findings contradict previous promising preliminary studies and may be due to the trial's limited sample size and patient selection.
A study of 3,900 patients reveals a decline in age and an increase in obesity rates among those suffering from severe heart attacks. The findings highlight the need for greater emphasis on preventive lifestyle changes to address rising risk factors such as smoking, high blood pressure, and diabetes.
Patients with coronary artery disease diagnosed with depression are more likely to suffer a heart attack or die compared to those without depression. Depression was also associated with more severe chest pain and co-existing medical conditions.
A new study published in The BMJ found no evidence that selective serotonin reuptake inhibitors (SSRIs) increase the risk of cardiovascular conditions like heart attacks and strokes in people under 65. In fact, SSRIs may reduce the risk of heart attacks, particularly with fluoxetine use.
A new risk model and risk score have been developed to identify patients at high risk of sudden cardiac death (SCD) after non-ST-segment elevation acute coronary syndrome (NSTE ACS). The cumulative incidence of SCD was found to occur continuously over time, with a rate of approximately 1 percent per year.
A new study reveals genetically inherited high levels of cholesterol are more prevalent than previously believed, affecting an estimated 834,500 U.S. adults. Researchers found that familial hypercholesterolemia (FH) affects both men and women equally, with varying prevalence rates across racial groups.
Research reveals gut microbes produce compound TMAO, which encourages over-reactive platelet function, increasing thrombosis risk. Higher TMAO levels linked to heart attacks and strokes in humans.
A study found that men who received healthy lifestyle advice for five years had a sustained 29% reduced risk of death from first heart attack, even after 40 years. Participants were advised to reduce saturated fats and increase fish and vegetable consumption.
Researchers discovered a mutated ANGPTL4 gene that lowers triglyceride values in the blood, reducing the risk of coronary disease. This breakthrough may lead to new medications that simulate the effect of this mutation, providing a concrete goal for future research.
A study published in the European Heart Journal found that improved lifestyles led to a significant decrease in cholesterol levels, resulting in reduced cardiovascular disease and cardiac death. The study shows that changes in diet and lifestyle had a more pronounced effect on older individuals and those with high risk of cardiovascula...
Research suggests that moderate drinking poses an immediate higher cardiovascular risk, but this risk lessens and can become protective after 24 hours. Heavy drinking, on the other hand, heightens short- and long-term risks of heart attack and stroke.
Researchers found that reducing fruit and vegetable prices could decrease cardiovascular deaths by 1.2% in five years, while increasing sugary drink prices could lead to a 0.25% decrease in heart attacks. Implementing such policies nationwide could potentially prevent 515,000 deaths from cardiovascular disease.
A University of Louisville cardiologist is conducting a study to determine if certain lipids in blood can be used to identify women at risk for a heart attack. The presence of oxidized phospholipids may allow doctors to pinpoint women with increased risk before permanent damage occurs.
Researchers have discovered that a new medication, pioglitazone, can reduce the risk of stroke and heart attack by nearly a quarter in patients who have previously suffered a stroke or mini-stroke. This breakthrough finding presents a promising new strategy for preventing cardiovascular disease.
Women who become pregnant at age 40 or older face a greater risk of stroke and heart attack later in life compared to younger women. Established cardiovascular risk factors explained most of the higher risk, but not the link between advanced age pregnancy and hemorrhagic stroke.
A global study suggests that pioglitazone, a diabetes drug, can prevent recurrent stroke and heart attacks in people with insulin resistance but without diabetes. The Insulin Resistance Intervention after Stroke (IRIS) trial found a 24% relative decrease in stroke or heart attack risk among patients taking pioglitazone.
A study found that heart attack patients who experience cardiogenic shock have a higher risk of death or rehospitalization in the first 60 days post-discharge. However, by the end of the first year, the gap between the two groups narrows.
Researchers found that metformin enhances new blood vessel formation and reverses oxygen delay during a heart attack. The study suggests that the medication can aid in heart attack recovery by promoting the growth of new blood vessels.
Men who experienced a family member's incarceration during childhood are approximately twice as likely to have a heart attack in later adulthood compared to those without such exposure. The study also found no association between childhood family member incarceration and heart attacks in women.
Researchers found that individuals with higher MET scores (indicating higher physical fitness) had a 40% lower mortality rate after a first heart attack. The study, published in Mayo Clinic Proceedings, suggests that doctors should recommend exercise programs to patients at risk of cardiovascular disease.
A study of nearly 70,000 patients found that those with higher aerobic fitness before a heart attack are more likely to survive their first heart attack. Fitness levels were associated with improved short-term survival rates after the event.
A new scientific statement highlights differences in heart attacks between women and men, including different underlying causes, symptoms, and risk factors. Women are more likely to have atypical symptoms and undertreated with guideline-recommended medications, leading to worse outcomes.
A new scientific statement from the American Heart Association underscores the need to understand and treat heart disease in women. Women's hearts are different from men's, with unique symptoms such as palpitations, back pain, or jaw pain, which can be misdiagnosed due to lack of awareness.
Researchers review studies on PrEP and aspirin, finding similar low rates of serious side effects. PrEP works well to prevent HIV when taken daily, supporting efforts to make it available over-the-counter.
The NHS Health Check programme effectively identifies people at risk of cardiovascular incidents and helps diagnose conditions like type 2 diabetes, high blood pressure, and chronic kidney disease. The study found that the programme prevented 2,500 cases from treatment following the check over its first five years.
A new study by Cedars-Sinai Medical Center found that more than half of patients who experience sudden cardiac arrest ignore key symptoms prior to the event. These symptoms often include chest pain, shortness of breath, and palpitations, occurring up to a month before the fatal heart rhythm malfunction.
Researchers found that transradial rescue PCI was used in only 15% of cases, and those who were most prone to bleeding were more likely to be treated with transfemoral access. The study highlights the 'risk-treatment paradox,' where patients at high risk for a condition are less likely to receive aggressive treatment.
A recent study published in Annals of Internal Medicine found that patients with sudden cardiac arrest who received medical attention shortly after exhibiting warning signs had a significantly higher chance of survival compared to those who ignored their symptoms. Researchers collected data from survivors, family members, and medical r...
A study led by Dr Gerry McCann found that treating multiple narrowed arteries during a heart attack does not increase the amount of heart muscle damage. The research suggests it is safe for cardiologists to insert stents in all discovered narrowings while treating a heart attack.
Researchers found a strong association between negative news stories about statins and early discontinuation, increasing the risk of heart attacks and cardiovascular mortality. The study suggests that exposure to negative news can play a role in patients' decisions to stop taking their medication.
A study published in International Journal of Cardiology found that mildly elevated levels of bilirubin, a bile pigment, can reduce damage and improve heart function during recovery from a heart attack. Higher levels of bilirubin have also been shown to protect the circulation from oxidative damage.
A study found that young women who survived heart attacks or strokes had higher mortality rates from cardiovascular events, with an increased risk of cardiac and cerebral events. The researchers followed up with 226 women who had a heart attack, 160 women who had ischemic stroke, and 782 comparison patients for nearly 19 years.
A study of 1,400 patients compared IVUS-guided and angiography-guided drug-eluting stent implantation methods. The findings suggest better outcomes with IVUS-guiding, particularly for diffuse long lesions, with a significant reduction in ischemia-driven target lesion revascularization.
Disclosing genetic risk information for coronary heart disease results in lower low-density lipoprotein (bad) cholesterol levels. Participants who received genetic risk information showed nearly 10 milligrams per deciliter of blood lower LDL levels six months after risk disclosure.
A recent study has shown that when cells are deprived of oxygen and nutrients, their DNA becomes compacted into tight clusters. This dramatic change reduces gene activity and leads to cell shutdown. The discovery may help researchers develop new treatments for diseases such as heart attacks, strokes, and cancer.
A new study of 1,472 healthy men found that testosterone supplementation did not increase the risk of heart attack, stroke, or death. Testosterone therapy was shown to reduce these risks compared to non-supplemented individuals.
A study of over 14,000 adults found those born with congenital heart disease have a 3.5 times higher risk of heart attack before age 50 and twice the risk after. Mortality rates are also significantly higher, with some cases showing a mortality rate four times that of the general population.
A study published in JAMA Network found that nearly 8% of the population has myocardial scars, indicating a 'silent' heart attack. The majority (78%) of these scars were undetected by electrocardiography or clinical evaluation, highlighting the need for improved detection methods.
A major new study found that people with heart disease face an increased risk of a serious heart attack during poor air quality days. Researchers at the Intermountain Medical Center Heart Institute identified a strong association between bad air quality days and a higher risk of STEMI, the most dangerous type of heart attack.