Articles tagged with Respiratory Disorders
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers identified a protein that inhibits human defense mechanisms and allows fungal growth. The study suggests that the lack of this enzyme makes the fungus more prone to elimination by the immune system.
Researchers use AI to predict COPD flare-ups based on daily urine tests, potentially allowing for proactive treatment and prevention. The study identifies biomarkers in urine that can forecast a flare-up seven days prior to symptoms.
A new AI program, PanEcho, has been developed to interpret echocardiography videos independently, reducing wait times and improving timely medical care. The program demonstrated accuracy in estimating continuous echocardiographic parameters and quantifying left ventricle dimensions and function.
A study by the University of Bonn and Universidade Federal de Minas Gerais shows that forest protection measures significantly reduce particulate matter in the air, leading to a decrease in hospital stays and deaths due to respiratory diseases. Protective measures are estimated to save around 680 human lives per year.
Scientists use machine learning-based classifiers to differentiate lung cancer and noncancer based on urinary miRNA ensembles. The study reveals high specificity and sensitivity in detecting early-stage lung cancer, offering new hope for improved patient outcomes.
Researchers are using genetic data from Le Bonheur and UT Health Science Center to better diagnose patients with childhood interstitial and diffuse lung diseases. The goal is to identify genetic causes and provide earlier diagnosis and treatment for this rare disease.
The partnership aims to co-develop innovative technologies for enhanced health and economic outcomes. Key findings include the need for collaborative research to counter emerging challenges presented by tropical ID, and inform pandemic preparedness strategies.
Upgrading home insulation can lower medical bills and extend healthy lives by reducing blood pressure and CVD risk. Simulations showed that upgrading or retrofitting insulation is cost-effective for many homeowners, with significant health benefits justifying the costs.
Research from Karolinska Institutet finds that abnormal BMI in children can lead to impaired lung function, but normalizing BMI before adulthood may offset this. The study, which followed over 4,000 children, also found a correlation between low BMI and reduced lung growth.
A study from Queen Mary University of London reveals that nearly half of African pupils with asthma symptoms have undiagnosed cases, highlighting the need for better access to diagnosis and treatment. The research found that only a small percentage of diagnosed pupils were using medication effectively.
A multi-state study published in The Lancet found the RSV vaccine to be highly effective in protecting older adults against severe disease, hospitalization, and death. The vaccine provided approximately 80% protection against these outcomes, including severe disease and ICU admission.
Researchers are creating microphysiological systems to simulate infection and treatment in vitro, linking human lung and brain tissue models. This project aims to explore the relationship between respiratory diseases and neurological symptoms, potentially leading to new treatments.
Research finds that increases in air pollution levels correspond with a higher number of patients visiting the hospital emergency department, particularly for cases of trauma, breathing difficulties, and skin conditions. The study suggests that heavy traffic is directly responsible for increased trauma cases and indirectly contributes ...
Researchers will showcase results of a randomized clinical trial demonstrating Biovanta's efficacy in reducing common cold symptoms by strengthening the respiratory barrier and controlling inflammation. The presentation will also include preclinical data on antiviral formulas targeting rhinovirus and influenza.
Researchers at La Jolla Institute for Immunology have developed six lines of humanized mice to study human cases of COVID-19, shedding light on SARS-CoV-2's movement through the body and varying symptoms. The models help understand how different genetic backgrounds influence disease progression.
The American College of Chest Physicians has released a new clinical guideline on endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) specimen processing and handling to standardize the process. The guidelines aim to improve diagnostic yield and specimen preservation for downstream ancillary testing.
Researchers compared epigenetic changes across the genome in young adults who vaped, smoked or did not use nicotine products, finding a tumor-suppressor gene among the key findings. The study found substantial overlap in DNA methylation patterns between people who vaped versus those who smoked.
Researchers at Texas A&M University have developed a method to recharge cellular mitochondria using nanotechnology, potentially extending healthy lifespans and improving outcomes for patients with age-related diseases. The molybdenum disulfide nanoparticles stimulate mitochondrial regeneration, helping cells generate more energy.
Patients using transparent capsules delivered more medication due to visual feedback on their inhalation technique, leading to better management of chronic airway diseases. The study found a significant 30.1% reduction in capsule weight after inhalation.
Researchers analyzed over 150,000 COVID-19 cases in Japan and found CAPA occurred in 0.4% to 2.7% of severe or critical patients, with higher risk seen in men, older adults, and those with respiratory diseases. Early detection and treatment with antifungal drugs are crucial for improved outcomes.
A clinical trial found that sulthiame, a drug used for epilepsy, reduces pauses in breathing and improves oxygen levels in patients with obstructive sleep apnea. The treatment also alleviates daytime fatigue, suggesting it could be an effective alternative to existing mechanical treatments.
A large study found that women with asthma are more likely to miscarry and require fertility treatment, but most can still have babies. The study analyzed reproductive outcomes for over 700,000 Danish women, finding higher rates of foetal loss and fertility treatment among those with asthma.
A new study found that RSV vaccination programs targeting older adults with underlying health conditions are more likely to be cost-effective than general age-based strategies. Vaccinating people aged 70 years and older with chronic medical conditions is likely to be cost-effective based on commonly used cost-effectiveness thresholds.
Researchers developed an AI model to detect lung disease in premature babies by analyzing their breathing patterns while sleeping. The Long Short-Term Memory (LSTM) model achieved 96% accuracy in classifying flow values as belonging to a patient with BPD or not, enabling early diagnosis and treatment.
A Cornell University-led collaboration has developed a machine learning model that uses cell-free molecular RNA dregs to diagnose pediatric inflammatory conditions, including Kawasaki disease and Multisystem Inflammatory Syndrome in Children. The diagnostic tool accurately determines the patient's condition while monitoring organ health.
A recent study presented at the European Respiratory Society Congress found that young vapers performed worse in exercise tests compared to non-vapers and smokers. The research showed that vaping was associated with lower peak exercise capacity, reduced oxygen consumption, and signs of blood vessel dysfunction.
A study found that medical clowns can reduce hospital stays by an average of 43.5 hours and decrease IV antibiotic use for children with pneumonia. The clowns' visits also led to lower respiratory rates, heart rates, and inflammatory markers.
A study found that ChatGPT performed better than trainee doctors in assessing complex cases of respiratory disease in areas such as cystic fibrosis and asthma. The chatbot's responses were also scored higher for being human-like, while Google's Bard and Microsoft's Bing performed similarly to or worse than trainees.
Two studies found that long-term exposure to air pollution increases the risk of hospitalization for respiratory conditions, including asthma and COPD. Green spaces may actually increase emergency room visits for respiratory issues when combined with hay fever.
A study published by the European Respiratory Society found that hypertonic saline nasal drops reduced the length of the common cold in children by an average of two days. The treatment also reduced the need for medicines during illness and decreased family members catching a cold.
Researchers discovered faulty immune processes responsible for lingering lung issues after COVID-19, which can be disrupted by existing drugs. The study also identified molecules responsible for the issue and potential therapeutic options for patients with ongoing lung damage.
Non-Communicable Diseases (NCDs) are a major global health issue, characterized by their chronic nature and long-term impact on quality of life. In China, understanding the extent and distribution of NCDs is essential for developing effective public health strategies.
A study found that RSV vaccination significantly reduced hospitalization risk among adults 60+ in the US, offering protection against severe RSV disease. The vaccine demonstrated effectiveness in high-risk populations, including those over 75 and with immunocompromising conditions.
A subset of CD4 T cells create an anti-inflammatory environment within the lung tissue, protecting against TB reinfection by limiting bacterial growth and disease severity. The discovery complements previous research on protective immune T cells in controlling TB infection, suggesting a potential key to improving existing vaccines.
A team of researchers, led by Jason Shoemaker, are studying the effects of hormones on the immune system's response to the flu. Their goal is to develop targeted therapies based on a person's sex or hormone levels. The study aims to identify the molecules or pathways that affect the cells and begin to develop personalized treatments.
Researchers have developed a suite of parameters that can be used to quantitatively measure different physical characteristics of the lung. The parameters were found to be highly sensitive and specific for diagnosing fibrosis and edema in an animal model, using only five necessary parameters.
A new study found that routine laboratory tests are not reliable for diagnosing Long COVID, with no biomarker among 25 clinical laboratory values providing a clinically useful diagnosis. The researchers suggest treating symptoms rather than relying on lab results to diagnose the condition.
Researchers found high expression of OLAH linked to fatal disease outcomes, while low levels were associated with recovery. The enzyme drives severe disease through inflammatory responses and fatty acid production.
Researchers from POSTECH and KRICT created a 3D artificial lung using bioprinting technology, closely mimicking the human respiratory tract. This model allows for accurate testing of COVID-19 drugs and development of therapeutic treatments, potentially shortening the drug development process to under 5 years.
A new study from the University of Surrey found that higher faecal bacterial diversity at one month old is positively associated with the athletic performance of Thoroughbred foals. Lower bacterial diversity in early life also increases the risk of respiratory disease and soft-tissue issues.
Researchers found that children's immune systems attacked their own tissues after latching onto a coronavirus protein resembling one found in multiple organs. Early intervention was crucial to prevent death in these cases, and the study has implications for understanding other autoimmune diseases.
A new study from Murdoch Children's Research Institute has identified changes in certain blood proteins that can predict bronchopulmonary dysplasia (BPD) in preterm babies. By combining these protein changes with gestational age, birth weight, and sex, clinicians can make more accurate predictions of BPD risk within 72 hours of life.
Researchers at the University of Houston have developed two nasal sprays, NanoSTING and NanoSTING-SN, to prevent respiratory virus transmission. NanoSTING is an immune activator that can protect against multiple viruses, while NanoSTING-SN is a pan-coronavirus vaccine that can prevent transmission to unvaccinated individuals.
The review paper examines the scope of people affected by long COVID, ranging from fatigue to cognitive impairment, and current treatment options. Researchers emphasize the need for biomarkers and targeted therapies to address root causes of the disease.
A new model developed by Penn State researchers more accurately predicts the causal relationship between genetic and environmental factors in disease development. The study found that lifestyle and environmental factors play a larger role than previously believed, offering new opportunities to mitigate disease risk.
Researchers at UC San Francisco found a link between healthy diets and a younger biological age. Even when people eat healthy diets, each gram of added sugar is associated with an increase in epigenetic age. The Mediterranean diet had the strongest association with lower epigenetic age.
The American College of Chest Physicians has released a new clinical guideline for managing central airway obstruction, providing evidence-based recommendations to guide its management. The guideline emphasizes the importance of shared decision-making and a multidisciplinary approach in optimizing care and improving outcomes.
Researchers created a new cell model to study the effects of senescence on lung fibroblasts. Senescent alveolar epithelial cells triggered fibrotic activation in lung fibroblasts, which was attenuated by senolytic therapy.
The study compared FDG-PET/CT and CT for evaluating treatment response in unresectable malignant pleural mesothelioma patients. The results showed that both imaging modalities provided accurate findings for tumor response evaluation, with high concordance between the two methods.
The Tulane University-led COBRE will investigate biological sex and gender differences to improve medical outcomes, focusing on differences in autoimmune diseases, pneumonia infections, and treatment responses. The center aims to develop sex-specific miniaturized models of human tissues and organs to study disease progression.
A new study reveals that micro- and nanoplastics may boost the risk of non-communicable diseases such as cancer, diabetes, and cardiovascular disease. The tiny particles are absorbed into the human body through food, air, and other sources, potentially leading to increased inflammation and severity of these conditions.
Researchers used single-cell sequencing technology to study immune responses in healthy adult volunteers exposed to SARS-CoV-2. They discovered unique immune responses associated with resisting sustained viral infection and disease, including activation of specialized mucosal immune cells and a reduction in inflammatory white blood cells.
A Pusan National University study finds that heatwaves significantly impact public health among individuals with disabilities, increasing the risk of hospitalizations by 1.07 times. This results in a substantial economic burden, highlighting the need for well-informed public health policies to address these vulnerable groups.
Research finds that Huntington’s disease damages microscopic blood vessels in the brain, affecting coordination between neuronal activity and oxygenation. The study uses non-invasive measurement techniques to monitor disease progression and evaluate potential treatments.
A new study has found that FAPI PET/CT is more effective than FDG in predicting progressive pulmonary fibrosis in ILD patients. The study's results suggest that FAPI PET/CT can identify high-risk patients who require closer monitoring or preventive treatment.
Scientists discover Epstein-Barr virus alters gene regulation in nasopharyngeal cancer cells, leading to rapid tumour growth. The study offers new insights into the link between EBV and NPC, shedding light on intricate processes underlying disease progression.
By 2050, at least 61% of US adults (184 million people) are projected to have some type of cardiovascular disease, with total costs tripling to $1.8 trillion. Population shifts, high blood pressure, and obesity will drive this increase.
Early admission of COVID-19-positive patients to skilled nursing facilities was associated with preventable cases and mortality among residents. Facilities with staff and PPE shortages were disproportionately affected, underscoring the importance of adhering to infection-control protocols.
The American College of Chest Physicians' CHEST Critical Care and CHEST Pulmonary journals have been indexed with the Directory of Open Access Journals (DOAJ), enhancing their open access content's accessibility and usage. The indexation is attributed to strong editorial boards led by Hayley Gershengorn and Matthew Miles.
Weo electrolyzed water (WEW) has been shown to attenuate cellular senescence in both normal fibroblasts and breast cancer cells. The study found that WEW modulated markers of cellular senescence, inflammation, and stress response genes in a cell type-dependent manner.