Articles tagged with Respiratory Disorders
A USF study found that patients with pulmonary fibrosis who contracted severe COVID-19 experienced lung improvement. Researchers are exploring factors associated with this finding to develop new treatments, including applying knowledge gained from COVID-19 patients to idiopathic pulmonary fibrosis patients. The study suggests a possibl...
The American Thoracic Society is opening media registration for ATS 2025, taking place May 18-21 in San Francisco. Registered journalists will have access to emerging scientists and clinicians discussing medical breakthroughs and clinical innovation.
Exposure to air pollution during the three months before pregnancy is associated with higher childhood obesity risk up to two years after birth. The study found that women with higher levels of PM2.5 and PM10 had children with a higher BMI and related obesity risk factors.
Preschool wheeze affects 30-40% of children under six, causing significant morbidity and healthcare costs. The UK has the second-highest prevalence in Europe, with inconsistent terminologies used by doctors contributing to diagnostic challenges.
A new study found that while lung cancer deaths decreased globally from 1990 to 2019, mortality linked to tobacco use and air pollution increased. Tobacco remains the leading cause of death, accounting for 66% of TBL cancer deaths in 2019, while particulate matter pollution is a growing concern.
Stephania Cormier and colleagues lead a Frontiers in Immunology research collaboration to explain RSV's complex interplay with host immune responses. The team identifies gaps in knowledge, hindering therapeutics and vaccines development.
Researchers document five cases of parvovirus B19-induced myocarditis in preschoolers from northern Greece, highlighting the virus's unique impact on endothelial cells. The study emphasizes the importance of quick diagnosis and treatment to reduce mortality and morbidity in children.
A study published in ERJ Open Research found that women are less likely to receive a lung transplant and wait an average of six weeks longer for one. Despite this, women who undergo transplantation have higher survival rates five years post-transplant.
A recent case series suggests that an extended course of Paxlovid may help some patients with long Covid experience sustained improvements in their symptoms. The study, published in Communications Medicine, found that five out of 13 patients experienced significant symptom relief after taking the antiviral drug for 15 days.
Researchers at the University of Pittsburgh developed a non-invasive nasal swab test that diagnoses specific asthma subtype, or endotype, in children. The test, published in JAMA, shows promise for improving asthma treatment outcomes and paving the way for better treatments for lesser-studied asthma types.
John Howington, MD, MBA, FCCP, is the new President of CHEST, succeeding Neil S. Freedman, who will be President-Elect in 2026. Dr. Howington has extensive leadership experience and has published over 49 research publications.
A USTC research team developed a non-invasive RF-based system for monitoring heart rate variability with clinical-grade accuracy over extended periods. The system successfully overcomes interference from respiratory motion and performs well in automatic classification of heartbeat abnormalities.
A University of Toronto study discovered a new communication pathway between the gut and lung, highlighting the role of a little-known protozoan in shaping immune responses. The study found that this microbe can worsen airway inflammation in allergic asthma but provide protection against respiratory infections.
Cases of whooping cough are increasing in the US, with over 28,000 cases reported this year. A nationally representative survey found that many people lack knowledge about the disease's symptoms and vaccine effectiveness.
A six-year study examining 38 clinical isolates of Cryptococcus found genes and gene alleles associated with disease severity. The research aims to develop new treatments targeting these genetic variations, predicting disease outcomes and improving patient care.
Longidaza significantly reduced exertional desaturation and dyspnea, as well as improved distance walked during the six-minute walk test. The drug's effects on exercise tolerance were sustained for over 100 days after treatment.
Researchers found that children with primary ciliary dyskinesia (PCD) are 22 times more likely to have asthma compared to those without PCD characteristics. The study suggests that some children diagnosed with asthma may have undiagnosed PCD, particularly if they exhibit unique respiratory symptoms.
Five Texas researchers have been honored with the 2025 Edith and Peter O'Donnell Awards for their innovative breakthroughs in small cell lung cancer, lithium-ion battery technology, and galaxy discovery. Lauren Averett Byers is being recognized for her work on novel therapeutic strategies for SCLC, while Caitlin M. Casey is exploring p...
The study analyzed the high burden of RSV-associated acute respiratory illness among young children in the U.S. and found nirsevimab to be effective against severe cases, highlighting the potential for substantial public health impact through increased prevention coverage.
The PoweRD 2 Cure ALK+ Lung Cancer TeamLab aims to identify and exploit vulnerabilities of leftover cancer cells to prevent recurrence. By combining new strategies, structures, and thinking from across disciplines, researchers hope to develop treatment strategies that leave no cancer cells alive.
Research reveals that people who use both vapes and cigarettes are less likely to quit smoking compared to those who only smoke or vape. Dual users tend to revert to only smoking cigarettes over time. The study suggests that taking up vaping while continuing to smoke will not help people stop smoking.
A major European survey found that seven out of ten homes are smoke-free, with countries like England and Ireland scoring high. In contrast, Greece and Romania have more than half of their homes allowing smoking. The researchers highlight the need for stronger tobacco control measures to protect children and adults from second-hand smoke.
Researchers found lower pulmonary gas exchange may be associated with impaired cognitive function in patients with long COVID. The study also showed a potential treatment strategy using methods that target improved gas exchange, suggesting a causative relationship between cognitive dysfunction and lung dysfunction.
The surgical team led by Stephanie H. Chang performed the groundbreaking procedure using da Vinci Xi robotic system at NYU Langone Transplant Institute. The successful transplant marks a significant milestone in lung transplantation surgery, offering hope to patients with chronic obstructive pulmonary disease (COPD) like Cheryl Mehrkar.
A new study from the University of Copenhagen found that nicotinamide riboside can reduce lung inflammation in COPD patients, leading to a significant drop in inflammation markers and improved lung function. The treatment also showed signs of delaying cellular aging.
Researchers use AI to predict COPD flare-ups based on daily urine tests, potentially allowing for proactive treatment and prevention. The study identifies biomarkers in urine that can forecast a flare-up seven days prior to symptoms.
Researchers identified a protein that inhibits human defense mechanisms and allows fungal growth. The study suggests that the lack of this enzyme makes the fungus more prone to elimination by the immune system.
A new AI program, PanEcho, has been developed to interpret echocardiography videos independently, reducing wait times and improving timely medical care. The program demonstrated accuracy in estimating continuous echocardiographic parameters and quantifying left ventricle dimensions and function.
A study by the University of Bonn and Universidade Federal de Minas Gerais shows that forest protection measures significantly reduce particulate matter in the air, leading to a decrease in hospital stays and deaths due to respiratory diseases. Protective measures are estimated to save around 680 human lives per year.
Scientists use machine learning-based classifiers to differentiate lung cancer and noncancer based on urinary miRNA ensembles. The study reveals high specificity and sensitivity in detecting early-stage lung cancer, offering new hope for improved patient outcomes.
Researchers are using genetic data from Le Bonheur and UT Health Science Center to better diagnose patients with childhood interstitial and diffuse lung diseases. The goal is to identify genetic causes and provide earlier diagnosis and treatment for this rare disease.
The partnership aims to co-develop innovative technologies for enhanced health and economic outcomes. Key findings include the need for collaborative research to counter emerging challenges presented by tropical ID, and inform pandemic preparedness strategies.
Upgrading home insulation can lower medical bills and extend healthy lives by reducing blood pressure and CVD risk. Simulations showed that upgrading or retrofitting insulation is cost-effective for many homeowners, with significant health benefits justifying the costs.
Research from Karolinska Institutet finds that abnormal BMI in children can lead to impaired lung function, but normalizing BMI before adulthood may offset this. The study, which followed over 4,000 children, also found a correlation between low BMI and reduced lung growth.
A study from Queen Mary University of London reveals that nearly half of African pupils with asthma symptoms have undiagnosed cases, highlighting the need for better access to diagnosis and treatment. The research found that only a small percentage of diagnosed pupils were using medication effectively.
A multi-state study published in The Lancet found the RSV vaccine to be highly effective in protecting older adults against severe disease, hospitalization, and death. The vaccine provided approximately 80% protection against these outcomes, including severe disease and ICU admission.
Researchers are creating microphysiological systems to simulate infection and treatment in vitro, linking human lung and brain tissue models. This project aims to explore the relationship between respiratory diseases and neurological symptoms, potentially leading to new treatments.
Research finds that increases in air pollution levels correspond with a higher number of patients visiting the hospital emergency department, particularly for cases of trauma, breathing difficulties, and skin conditions. The study suggests that heavy traffic is directly responsible for increased trauma cases and indirectly contributes ...
Researchers will showcase results of a randomized clinical trial demonstrating Biovanta's efficacy in reducing common cold symptoms by strengthening the respiratory barrier and controlling inflammation. The presentation will also include preclinical data on antiviral formulas targeting rhinovirus and influenza.
The American College of Chest Physicians has released a new clinical guideline on endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) specimen processing and handling to standardize the process. The guidelines aim to improve diagnostic yield and specimen preservation for downstream ancillary testing.
Researchers at La Jolla Institute for Immunology have developed six lines of humanized mice to study human cases of COVID-19, shedding light on SARS-CoV-2's movement through the body and varying symptoms. The models help understand how different genetic backgrounds influence disease progression.
Researchers at Texas A&M University have developed a method to recharge cellular mitochondria using nanotechnology, potentially extending healthy lifespans and improving outcomes for patients with age-related diseases. The molybdenum disulfide nanoparticles stimulate mitochondrial regeneration, helping cells generate more energy.
Researchers compared epigenetic changes across the genome in young adults who vaped, smoked or did not use nicotine products, finding a tumor-suppressor gene among the key findings. The study found substantial overlap in DNA methylation patterns between people who vaped versus those who smoked.
Patients using transparent capsules delivered more medication due to visual feedback on their inhalation technique, leading to better management of chronic airway diseases. The study found a significant 30.1% reduction in capsule weight after inhalation.
Researchers analyzed over 150,000 COVID-19 cases in Japan and found CAPA occurred in 0.4% to 2.7% of severe or critical patients, with higher risk seen in men, older adults, and those with respiratory diseases. Early detection and treatment with antifungal drugs are crucial for improved outcomes.
A large study found that women with asthma are more likely to miscarry and require fertility treatment, but most can still have babies. The study analyzed reproductive outcomes for over 700,000 Danish women, finding higher rates of foetal loss and fertility treatment among those with asthma.
A clinical trial found that sulthiame, a drug used for epilepsy, reduces pauses in breathing and improves oxygen levels in patients with obstructive sleep apnea. The treatment also alleviates daytime fatigue, suggesting it could be an effective alternative to existing mechanical treatments.
Researchers developed an AI model to detect lung disease in premature babies by analyzing their breathing patterns while sleeping. The Long Short-Term Memory (LSTM) model achieved 96% accuracy in classifying flow values as belonging to a patient with BPD or not, enabling early diagnosis and treatment.
A Cornell University-led collaboration has developed a machine learning model that uses cell-free molecular RNA dregs to diagnose pediatric inflammatory conditions, including Kawasaki disease and Multisystem Inflammatory Syndrome in Children. The diagnostic tool accurately determines the patient's condition while monitoring organ health.
A new study found that RSV vaccination programs targeting older adults with underlying health conditions are more likely to be cost-effective than general age-based strategies. Vaccinating people aged 70 years and older with chronic medical conditions is likely to be cost-effective based on commonly used cost-effectiveness thresholds.
A study found that medical clowns can reduce hospital stays by an average of 43.5 hours and decrease IV antibiotic use for children with pneumonia. The clowns' visits also led to lower respiratory rates, heart rates, and inflammatory markers.
A study found that ChatGPT performed better than trainee doctors in assessing complex cases of respiratory disease in areas such as cystic fibrosis and asthma. The chatbot's responses were also scored higher for being human-like, while Google's Bard and Microsoft's Bing performed similarly to or worse than trainees.
A recent study presented at the European Respiratory Society Congress found that young vapers performed worse in exercise tests compared to non-vapers and smokers. The research showed that vaping was associated with lower peak exercise capacity, reduced oxygen consumption, and signs of blood vessel dysfunction.
Two studies found that long-term exposure to air pollution increases the risk of hospitalization for respiratory conditions, including asthma and COPD. Green spaces may actually increase emergency room visits for respiratory issues when combined with hay fever.
Researchers discovered faulty immune processes responsible for lingering lung issues after COVID-19, which can be disrupted by existing drugs. The study also identified molecules responsible for the issue and potential therapeutic options for patients with ongoing lung damage.
A study published by the European Respiratory Society found that hypertonic saline nasal drops reduced the length of the common cold in children by an average of two days. The treatment also reduced the need for medicines during illness and decreased family members catching a cold.
A study found that RSV vaccination significantly reduced hospitalization risk among adults 60+ in the US, offering protection against severe RSV disease. The vaccine demonstrated effectiveness in high-risk populations, including those over 75 and with immunocompromising conditions.
Non-Communicable Diseases (NCDs) are a major global health issue, characterized by their chronic nature and long-term impact on quality of life. In China, understanding the extent and distribution of NCDs is essential for developing effective public health strategies.
A subset of CD4 T cells create an anti-inflammatory environment within the lung tissue, protecting against TB reinfection by limiting bacterial growth and disease severity. The discovery complements previous research on protective immune T cells in controlling TB infection, suggesting a potential key to improving existing vaccines.
A team of researchers, led by Jason Shoemaker, are studying the effects of hormones on the immune system's response to the flu. Their goal is to develop targeted therapies based on a person's sex or hormone levels. The study aims to identify the molecules or pathways that affect the cells and begin to develop personalized treatments.