Articles tagged with Skin Cancer
A recent study estimates that indoor tanning-related skin cancers in the US cause over 263,600 cases and cost $343.1 million in medical costs each year. The diseases also result in a total economic loss of $127 billion over the lifetime of those affected.
UNC-Chapel Hill researchers have made a breakthrough in treating glioblastoma by using human stem cells to hunt down and kill brain cancer. The new approach shows promise for clinical trials within the next one to two years.
A study from Queen Mary University of London discovered that thick skin on the palms and soles is linked to oesophageal cancer, a prevalent disease in the UK. Researchers found an inherited form of cancer called Tylosis, which causes severe skin thickening, also increases the risk of developing oesophageal cancer.
A new study reveals that changes in translation play a crucial role in the development of skin cancer. The researchers found that eIF2A, a protein involved in translating genetic instructions, is overexpressed in certain types of cancer and can serve as a potential therapeutic target for treating the disease.
A new study published in JAMA Dermatology found that non-heterosexual black male teens engage in indoor tanning at levels equal to those of heterosexual white females. This discovery highlights a surprising new group at risk for skin cancer, which may be linked to psychological distress and discrimination.
Researchers developed a dual strategy combining biomimetic beads and anti-PD1 therapy to boost killer T cell immunity against skin cancer. The combination technique increased T cell activation by 35% compared to artificial beads alone and 72% compared to anti-PD1 alone.
Researchers at Massachusetts General Hospital discovered a combination of calcipotriol and fluorouracil can rapidly clear actinic keratosis lesions by activating the immune system, achieving an 88% reduction in facial lesions. The treatment's effectiveness was compared to standard treatments, which elicit unpleasant side effects.
A new study published in Journal of Investigative Dermatology reports initial success with imiquimod, a topical skin cream for low-risk basal cell carcinoma lesions. The 5-year follow-up results show sustained efficacy and low recurrence rates for patients treated with imiquimod.
A new study shows that a combination of two topical drugs triggers a robust immune response against precancerous skin lesions, reducing their number by up to 88%. The therapy activates T cells to attack abnormal skin cells, offering a more effective and better-tolerated treatment alternative.
A new study found that around 17% of women diagnosed with breast cancer visit their doctor with a symptom other than a lump. Non-lump symptoms, such as nipple abnormalities and breast pain, were more likely to delay diagnosis compared to those with a breast lump alone.
A new study from Drexel University College of Medicine found that all organ transplant recipients, regardless of race, should receive routine total-body screenings for skin cancer. Nonwhite transplant recipients were more likely to have aggressive and deadly skin cancers due to anti-rejection medications.
A color-changing smart material sensor, developed by USC researchers, notifies users of their total UV exposure, allowing them to strike a balance between Vitamin D production and skin cancer prevention. The flexible patch, made from FDA-approved non-toxic polymers, works without a power source and can be stored for up to five weeks.
A study by London researchers found that standard radiation margins may not be large enough for all patients with non-melanotic skin cancer. Using protoporphyrin fluorescence, the team was able to determine more precise treatment volumes, resulting in improved patient outcomes and reduced recurrence rates.
Researchers at Mayo Clinic found bacterial DNA in breast tissue, even when sterile conditions are maintained. The team discovered significant differences in the breast tissue microbiome of women with and without cancer, suggesting a distinct role for the microbiome in breast cancer development.
Researchers at FAU aim to detect micrometastases and tumour markers using extracellular vesicles, improving cancer reoccurrence risk assessment for individual patients.
Dr. Jayne Weiss, an LSU Health New Orleans ophthalmologist, recommends using UV protection not just outdoors but also inside cars to prevent cataracts and skin cancer. She cites studies showing a 93% reduction in cell death when UV exposure is filtered through UV-absorbing auto glass.
A recent study found that human skin microbial communities remain highly stable over time, retaining unique signatures and resisting external perturbations. However, stability varied across individuals and sites, with oily areas showing more consistent bacterial and fungal communities.
A study found that primary care practices offering teledermatology services had a 64% increase in patients visiting a dermatologist compared to non-participating practices. This expansion of care improved access to dermatologists for Medicaid enrollees, particularly newly enrolled patients.
New research found that women with active sun exposure habits had a lower risk of heart disease and noncancer deaths. Smokers in the highest sun exposure group were at a similar risk as non-smokers avoiding sun exposure. The study's findings suggest that guidelines regarding sun exposure may be too restrictive, potentially harming health.
Geneticists at UNIGE sequenced DNA of skin tumors to determine genes responsible for cancerogenesis in basal cell carcinoma. New cancer genes MYCN, PTPN14 and LATS1 were identified, which can complicate treatment.
A study found that patients with inflammatory bowel disease and a history of cancer did not experience a significant increase in cancer risk when treated with anti-TNF therapy. In fact, 96% of patients were still alive and cancer-free after one year.
Researchers at The Hebrew University of Jerusalem have developed a nanotechnology-based delivery system that activates the body's natural defense against free radicals. This system could control various skin pathologies and disorders by inducing antioxidant enzymes and maintaining skin cell redox balance.
Researchers at the University of Arizona College of Pharmacy have discovered a compound found in annatto, a natural food additive, that prevents the formation of cancer cells and skin damage from UV radiation. The compound, bixin, may be valuable in the prevention and treatment of human skin cancers.
Recent research reveals that all dividing human skin cells have the potential to switch between two modes of cell division, one for maintenance and another for wound repair. This finding explains how skin grafts work and may lead to new treatments for wound healing and cancer.
Breast cancer incidence rates have increased among African American women, converging with those of white women. The rise is attributed to ER positive breast cancers and may reflect rising obesity rates. Black women are more likely to be diagnosed at later stages and have poorer survival rates due to lack of access to timely treatment.
Researchers have developed a radiotherapeutic bandage that has shown promise as an alternative therapy for squamous cell carcinoma (SCC) in an animal model. The bandages, which are made with nanoparticles containing inactivated radioactive material, can be individually tailored and manufactured on a large scale.
Nicotinamide significantly lowered the risk of common non-melanoma skin cancer in high-risk patients, reducing incidence by 23% compared to placebo controls. The treatment also cut the incidence of pre-cancerous sun spots by around 15%.
A recent meta-analysis found increased bladder cancer risk in certain occupations, with workers exposed to aromatic amines and polycystic aromatic hydrocarbons facing the highest risks. The study's findings suggest that efforts to reduce the impact of occupational bladder cancer should be targeted towards these high-risk occupations.
A UCSF study found that online ads about indoor tanning and skin cancer were effective in reaching a large audience, with one ad viewed by almost 200,000 users and generating a click-through rate of 1.04%. The researchers believe this approach could be used for other major public health issues.
A study using Google AdWords disseminated targeted messages about indoor tanning and skin cancer, with 235,913 ad views and 2,000 clicks. The campaign's effectiveness on changing behavior remains unknown, highlighting the need for further research.
A study published in JAMA Dermatology found that gay and bisexual men have a higher risk of skin cancer from indoor tanning compared to heterosexuals. The study also revealed significant disparities in skin cancer prevalence and indoor tanning behaviors among sexual minority women.
The new center aims to develop and translate new cancer care applications based on nanotechnology, focusing on melanoma and malignant brain cancers. Researchers will use Cornell dots, silica-organic hybrid nanoparticles, to improve cancer diagnostics, surgery, and targeted drug delivery.
A study found voriconazole significantly increases risk for skin cancer and death in lung transplant recipients, with a 73% greater risk for skin cancer. Physicians are advised to counsel patients on skin cancer risk and consider patient-specific factors when prescribing the drug.
Researchers developed a terahertz imaging system using COC substrates, enabling the detection of objects hidden under clothing or skin, and improving image resolution. The system has potential applications in airport security, medical diagnostics and food industry inspection.
Scientists have identified key genetic mutations leading to skin cancer progression, similar to those found in human cancers. By analyzing genetic abnormalities in premalignant and fully malignant tumors, researchers found that larger chromosomal copy number alterations were responsible for tumor formation, rather than point mutations.
A recent study published in Nature Genetics found that keratin 17 promotes tumor growth by driving a specific type of sustained inflammation that helps cancer develop aggressively. The protein is detected in various cancers and other skin diseases, but its role in tumor development was previously unknown.
A study surveyed patients about their knowledge of new sunscreen labels and found that most understood protection against sunburns but struggled with broad-spectrum protection. Fewer than half correctly identified terminology indicating skin cancer protection, leading to calls for improved labeling clarity.
A Northwestern Medicine study found that many people are confused by sunscreen terminology, with only 43% understanding SPF values and 7% knowing how to protect against early skin aging. This confusion can lead to inadequate protection against sunburns and premature skin aging.
MoleScope is an innovative hand-held tool that uses a smartphone to monitor skin for signs of cancer. The device has received approval from Health Canada and the FDA, and is expected to provide healthcare benefits in communities without access to medical specialists.
New study reveals that many known cancer-promoting genes are already present in normal, sun-exposed skin cells, even before they become cancerous. The researchers found that over 25% of normal skin cells carry at least one driver mutation, suggesting a higher frequency of cancer-causing mutations in normal skin than previously thought.
A study reveals that cancer-associated mutations exist in a significant percentage of normal skin cells, potentially offering insights into the origins of cancer. Researchers found that skin cells carry thousands of mutations caused by sun exposure, with around 25% carrying at least one cancer-associated mutation.
Researchers found that people are more likely to accept criticism and make changes if they take a broad, high-level construal view. This involves considering the big picture and believing change is possible. The study's findings have practical implications for delivering negative feedback in the workplace and health education campaigns.
Researchers say there is enough evidence to declare indoor UV radiation tanning causes skin cancer. The authors urge the US Surgeon General to make a stronger statement regarding UV tanning devices, citing eight out of nine Bradford Hill criteria as satisfied.
Researchers analyzed cytotoxicity and non-specific cellular uptake of upconversion nanoparticles (UCNPs) in human skin cells. UCNPs convert near-infrared radiation to visible light, allowing for detection and monitoring of cancerous cells.
A 10-year follow-up study of over 7,400 children found no significant association between topical pimecrolimus use and increased cancer risk. The study provides reassurance for the use of pimecrolimus in treating eczema in children.
The OHSU Knight Cancer Institute awarded $462,656 to 17 projects statewide to address community-identified needs and decrease the impact of cancer on Oregonians. The funded projects focus on preventing tobacco use among youth, increasing colorectal cancer screening, and developing skin cancer prevention programs.
A team of investigators at the University of Calgary has identified potential drug targets for neurocutaneous melanocytosis (NCM), a rare childhood cancer. The study used molecular analysis of patient tumor cells grown in animal models, revealing new insights into the disease's biology and suggesting possible treatments.
Researchers at King's College London identified a mechanism by which bacteria trigger tumour formation in skin damaged wounds. The study highlights the role of bacterial protein flagellin and immune receptor TLR-5 in this process.
A new study reveals SIRT6 can promote the development of skin cancers by increasing inflammation and cell proliferation. Inhibition of SIRT6 expression decreased COX-2 levels and tumor growth in mice.
A QUT study found that more than 50% of outdoor workers rated UV radiation exposure as a major concern. The study developed personalized sun protection action plans, which led to significant increases in workers' behaviors and attitudes towards sun protection.
Researchers discovered that chronic inflammation caused by metal allergy can promote the development of rare and aggressive skin cancers like Marjolin's ulcer. The study suggests that patients with metal implants near the skin may need to be monitored for this type of inflammation.
A genetic mutation caused by ultraviolet light is linked to millions of human skin cancers, according to Stanford researchers. The mutation occurs in the KNSTRN gene and can cause genomic catastrophe, leading to cutaneous squamous cell carcinomas.
Researchers at Loyola University Chicago Stritch School of Medicine discovered that dasatinib causes cancer cells to clump together, preventing metastasis. The drug targets a protein called BCR-ABL found in various malignancies, including breast and skin cancers.
Three plant-derived compounds, caffeic acid, rosmarinic acid, and trans-cinnamic acid, have been found to protect human skin cells from gamma radiation-induced damage during cancer radiotherapy. The compounds reduced reactive oxygen species and DNA damage by up to 40% and 15%, respectively.
A recent study published in JAMA Dermatology found that nearly 36.9% of skin cancer lesions are accompanied by itching, while 28.2% involve pain. Non-melanoma skin cancers are more likely to be associated with itch or pain.
Researchers at the University of Colorado Anschutz Medical Campus found that YouTube is a promising platform for disseminating research in dermatology. The study analyzed 100 videos with over 47 million views, driving 6,325 subscriptions to distinct user pages.
Researchers found that women with breast cancers involving the skin have widely varied survival rates, differing by tumor size and nodal involvement. They recommend adding a new staging category for tumors with skin involvement to accurately reflect a woman's chances of surviving her cancer.
A study published in the Journal of Behavioral Medicine found that fear and worry about skin cancer drive people's use of sunscreen, rather than information about the disease. The researchers suggest that addressing emotions may be crucial for designing effective public health interventions.
Chronic UV radiation stimulates endorphin production, causing physical dependence and addiction-like behavior in mice. This finding could explain why people have an instinctive desire for sunlight despite its health risks. Researchers suggest that a conscious effort to limit sun exposure is needed to mitigate skin cancer risk.
A new analysis found certain cancers are more concentrated in areas with high poverty, while others arise in wealthy regions. Areas with higher poverty have lower cancer incidence and higher mortality than those with lower poverty.