Articles tagged with Allergies
A genetic signature has been identified for eosinophilic esophagitis (EoE), a disease causing painful food allergies, inflammation, and swallowing difficulties. The microRNA signature is reversible with steroid treatment, offering an opportunity for non-invasive diagnosis and precise analysis.
A consortium of federal agencies and organizations has published a report proposing common measures and data-collection methods for asthma clinical research. The proposed standardization aims to compare results more efficiently, leading to improvements in asthma management and treatment.
Researchers identify RORalpha as critical for nuocyte development and allergic-like inflammation, offering new therapeutic strategy targets. The discovery has the potential to treat asthma and other allergic diseases, addressing growing global prevalence.
A new study found that children living in areas with lower levels of sunlight are at greater risk of developing food allergies and eczema. The research team analyzed data from Australian children and found a link between latitude and allergies to peanut and egg, as well as a higher prevalence of eczema in the south compared to the north.
Scientists from NIAID outline key advances in understanding and combatting infectious diseases, including the development of vaccines to prevent many infections. They also note the ongoing challenge of emerging pathogens, such as HIV, which can have devastating effects on societies.
Researchers at Mass Eye and Ear aim to understand the origins of eye allergies, a major health problem in the US. They hope to uncover more effective targets for treatment, potentially offering new hope for those suffering from ocular surface allergy.
A study by Lidia Morawska and colleagues found that older vacuum cleaners, even those with HEPA filters, release higher levels of fine dust and bacteria into the air. Newer models were generally less polluting, suggesting age and cost can impact emission rates.
Researchers found that hay fever symptoms peak in the first half of the grass pollen season, regardless of medication use. Symptoms decrease later on, but may be attributed to desensitization or less allergenic pollen.
Researchers recommend 10 key areas for research, including large cohort studies, interdisciplinary approaches, and the development of new tools and models. Effective public-private partnerships are also essential for advancing understanding of chronic inflammatory diseases.
Researchers at University of Copenhagen found that children born vaginally with diverse gut bacteria have lower risk of allergies. The study suggests that early exposure to a variety of bacteria is crucial for a healthy immune system, contradicting the long-held notion that bacteria are a threat to public health.
Research published in The Journal of Physiology identifies a link between maternal diet and child allergies, finding that polyunsaturated fatty acids improve gut immune cell response. This may reduce allergy risk by accelerating the development of a healthy immune system.
The American Thoracic Society (ATS) criticizes the White House's decision not to issue a final standard on ozone pollution, which poses significant health risks. Scientific studies have linked high ozone levels to severe respiratory issues and even premature death.
Researchers identify key protein ABCCC1 in clearing Alzheimer's beta-amyloid from the brain. A mutation in PSMB8 gene causes Japanese autoinflammatory syndrome with lipodystrophy. Signaling via TACI is crucial for long-lived antibody-secreting cells in a mouse model of flu infection.
A new study found that a nasal spray containing capsaicin from chili peppers reduces symptoms of non-allergic rhinitis. The study showed participants experienced faster relief after using the spray, on average within one minute.
A University of Melbourne study found that wheezy toddlers who react to house dust mites are more likely to develop asthma by age 12. The study identified a strong correlation between sensitivity and severe wheeze and asthma.
Using powder-free latex gloves significantly reduced the rate of latex sensitization among healthcare workers. A study found a 16-fold reduction in latex sensitization after institutions switched to powder-free gloves, preventing allergic sensitization and allowing some sensitized workers to lose sensitivity.
A study by Henry Ford Hospital found that prenatal pet exposure is associated with lower IgE levels in infants, reducing the risk of allergies and asthma by age 2. The findings also suggest that delivery mode and race can influence allergy development.
A recent study published in the Journal of Allergy and Clinical Immunology found that using hypoallergenic baby formula does not decrease the risk of allergies in high-risk infants. The trial involved 620 infants and assessed whether hypoallergenic formula could prevent childhood eczema, asthma, or hay fever up to seven years of age.
Researchers analyzed dust samples from 173 homes with a dog to evaluate hypoallergenic breeds. They found no significant differences in allergen levels between hypoallergenic and non-hypoallergenic dogs.
A new vaccine has been developed by McMaster University researchers, effective in treating people with cat allergies. The peptide immunotherapy vaccine is given through skin injections and may require fewer doses than traditional allergy shots, reducing side effects.
A study of over 3,000 children found a correlation between low vitamin D levels and an increased likelihood of developing allergies, including food and environmental allergens. Children with vitamin D deficiency were 2.4 times more likely to have a peanut allergy.
A USDA study found that ragweed pollen season in North America has increased by almost a month, correlating with seasonal warming shifts and climate change. The study supports the impact of climate change on public health and agriculture.
A new Cochrane Systematic Review finds sublingual immunotherapy significantly reduces symptoms of allergic rhinitis and medication requirements. The treatment has very few serious adverse effects and is effective in children, offering a convenient alternative to injection immunotherapy.
A University of Michigan School of Public Health study found that people exposed to higher levels of triclosan were more likely to report allergies and hay fever. Additionally, BPA exposure was associated with impaired immune function in adults, but only for those over 18 years old.
A Stanford University School of Medicine study suggests an alternative to standard nasal sprays that use preservatives, which can cause side effects. The new method maintains sterility in the applicator bottle without chemical preservatives.
Presenteeism, a measure of productivity loss due to health issues, may be overreported. The University of Michigan's School of Kinesiology suggests a three-year moratorium on studies due to inaccurate calculations and limited data collection methods.
Researchers found that pregnant women who consumed peanuts during pregnancy had infants with strong sensitivity to peanuts. The study suggests a potential risk factor for peanut allergy in infants, highlighting the need for further research.
A child's chances of developing allergies or wheezing are related to their growth in the womb, according to new research. Fetuses that grow quickly early on but falter later may be more likely to develop allergies and asthma as children.
Children with dog allergies who own a dog before age 1 are less likely to develop eczema by age 4, while cat ownership increases the risk among those allergic to cats. The study suggests parents consider pet choice when caring for at-risk children.
The NIH has renewed a research program to develop medical countermeasures for radiation exposure after a radiological or nuclear attack. The program will support research at seven institutions nationwide and provide an estimated $105 million in funding.
Researchers at Mount Sinai School of Medicine are expanding their studies on immunotherapies for peanut and egg allergy through a renewed $29.9 million grant from the NIH. The team is also investigating new treatments, including a peanut protein patch applied to the skin to treat peanut allergy.
A new study from Tel Aviv University suggests that mothers who feed their babies cow's milk in the first 15 days of life may be protecting them from developing an allergy to cow's milk protein later in life. The study found that babies who were fed cow milk protein early, in the form of infant formula, were almost completely protected ...
A study demonstrates that Pycnogenol, a natural plant extract from pine bark, substantially improves symptoms of hay fever. By reducing pollen-specific antibodies and inflammation, Pycnogenol effectively relieves eye and nasal symptoms in patients with allergic rhinitis.
A new blood test can predict whether newborn babies are at high risk of developing allergies as they grow older, thanks to research involving the University of Adelaide.
A new study links brain tumor growth to reduced expression of over 600 immune system genes, revealing the complexity of the immune response to cancer. The research found that immune function genes were suppressed in almost 70% of genes examined, contradicting previous assumptions.
Chronic mouth breathing can lead to abnormal facial and dental development, poor sleeping habits and academic performance. Treatment options are available, including surgical removal of tonsils and adenoids, and orthodontic intervention.
Scientists have identified a region of chromosome 5 associated with eosinophilic esophagitis (EoE), a rare allergic disease. The study suggests that the thymic stromal lymphopoietin (TSLP) gene may play a role in EoE, and future research may lead to a genetic test and treatments.
Researchers have identified a potential new set of targets to improve the efficiency of pancreatic islet transplantation. The study found that treatment with an antibody targeting HMGB1 prevented early pancreatic islet loss and inhibited IFN-gamma production by NKT cells and Gr-1+CD11b+ cells.
Researchers found that nasal allergies may be involved in some cases of chronic sinus disease, suggesting a potential link between the two conditions. The study suggests using imaging tests to diagnose and treat patients with nasal allergies who also have chronic sinus disease.
Researchers found that exposure to environmental bacteria triggers a mild inflammatory response in pregnant mice, rendering their offspring resistant to allergies. This protective mechanism could potentially prevent allergies in people by conditioning the developing immune system to tolerate microbes and allergens.
New research suggests that daycare attendance in early childhood doubles respiratory problems, but does not prevent later asthma and allergies. Children who started daycare early were more likely to experience wheezing in the first year of life, but this effect reversed by age eight.
A study found that traditional measurements and markers of inflammation were not effective in predicting future asthma symptoms and exacerbations in well-treated patients with persistent asthma. Researchers hope to identify better clinical predictors for this complex disease.
Dr. Tobias M. Hohl receives the 2009 ICAAC Young Investigator Award for his groundbreaking work on Aspergillus fumigatus and its interaction with the pulmonary innate immune system. His research has improved understanding of echinocandid mechanisms of action.
Researchers at the La Jolla Institute have identified a previously unknown role of an enzyme in suppressing tumor growth, which may lead to new treatments for myeloproliferative diseases and certain types of leukemia. The discovery could also provide insights into the mechanisms underlying blood cancers.
A controlled diet study with human volunteers found that a 2:1 w6/w3 ratio mimics early human diets can reduce inflammatory signaling genes. This study provides the first evidence of large changes in gene expression as a mechanism for omega fatty acids' clinical effects
A UCSF study found that personalized self-management programs for asthma patients significantly improved medication adherence and disease control. The program, which included a 30-minute session with a healthcare professional, resulted in better health outcomes and reduced emergency department visits.
Researchers have identified a gene variant on chromosome 11 that is linked to an increased risk of atopic dermatitis, a chronic inflammatory skin disease. The study found that this variant is also associated with Crohn's disease and affects approximately 36% of the European population.
A study at the University of Gothenburg reveals that over 5% of individuals tested are allergic to linalool, a fragrance ingredient in many hygiene products. The risk increases with exposure, and EU legislation requires labeling of products containing linalool.
A new screening tool developed by Tel Aviv University researchers may help doctors advise young asthmatic adults on safer employment options and prevent asthma attacks triggered by physical exertion. The study found an indisputable connection between exercise and asthma, which could save lives.
REGiMMUNE receives significant funding from Japan's JST and NIBIO to advance its immunosuppressant ToleroVax for GvHD and allergy treatment reVax. The grants will support preclinical and clinical programs for these promising therapies.
A new study identifies specific characteristics of immune cells called CD8+ T cells that successfully destroy HIV-infected cells. These cells are able to load granules with proteins necessary for delivering a death-inducing molecule called granzyme B to infected cells.
Researchers found that allergy symptoms may protect against cancer by removing foreign particles and substances from organs that come into contact with them. However, the relationship between asthma and lung cancer is a special case where asthma actually increases lung cancer rates.
Sequella has received a $2.3 million NIH grant to develop SQ641, a promising new TB drug that demonstrates superior in vitro activity against Mycobacterium tuberculosis. The Phase 2 SBIR grant will fund critical path studies for delivery optimization and IND-related activities.
Researchers found that children with allergic rhinitis are more likely to experience headaches, facial pain, and ear aches. The study suggests that these symptoms may be under-appreciated sources of discomfort for many children, leading to reduced diagnoses and effective treatment.
Research led by the University of New South Wales found that individuals with atopic diseases such as asthma and hay fever are up to 40% less likely to develop NHL if they have multiple conditions. Chronic atopy is associated with a reduced risk, particularly in B-cell NHL cases.
The prevalence of allergies has increased, with patients facing inadequate specialist care and resources. Community pharmacists are suggested as a solution to bridge the treatment gap, according to a recent editorial in The Lancet.
A study published in the American Journal of Respiratory and Critical Care Medicine found that traffic-related pollution increases the risk of asthma, hay fever, and eczema in children by more than 50%. Children living closer to roads are at a higher risk due to increased exposure to pollutants and aerosols.
Dr. Anthony S. Fauci, director of NIAID, will be honored with the Presidential Medal of Freedom for his decades-long work on HIV/AIDS research and treatment. The award recognizes his efforts to advance human knowledge and bring hope and healing to millions worldwide.
Recent studies suggest that specific immunotherapy can be an effective treatment for allergies, reducing symptoms and adverse reactions. The Institute also found that certain measures, such as quitting smoking and taking probiotics during pregnancy, may help prevent allergies in children.
A new study finds that air pollution from sulfur dioxide, fine particles, and nitrogen dioxide can cause decreased lung function and increase asthma symptoms in inner-city children. The study suggests that current air quality standards may not be sufficient to protect these vulnerable populations.