Articles tagged with Behavior Genetics
Researchers at the University of Tsukuba developed a novel technique to generate BM chimeric mice without irradiation, promoting cost-effectiveness and animal safety. This approach enables scientists to study the immune system in both healthy and diseased states using culture-based enrichment of hematopoietic stem and progenitor cells.
A large-scale study found that high caffeine intake may increase the risk of glaucoma by three-fold in individuals with a strong family history. Caffeine consumption above 480mg daily was associated with higher intraocular pressure and increased glaucoma prevalence.
A new study by NUI Galway confirms that Noble False Widow spider bites can cause severe envenomations, ranging from mild pain to debilitating symptoms and even hospitalization. The research team established a DNA database to identify the species, revealing that most bites occur in homes and around sleep sites.
A new study from Clemson University identifies specific cell clusters in the brain of fruit flies affected by acute cocaine exposure. The findings show widespread changes in gene expression and distinct differences between males and females, potentially leading to therapeutic development.
Researchers found genetic differences between city and rural great tits, with changes linked to cognition, aggression, and circadian rhythms. These adaptations enabled the birds to cope with urban stressors like noise pollution, lights at night, and air pollution.
A new study successfully treated flies displaying behavioral problems linked to schizophrenia-associated genes using common anti-psychotics. The research identified two key genes, Rim and CACNA1A/CACNA1B, which are involved in neurotransmitter release and electrical signaling in neurons.
A recent study led by NSU researcher sequenced the leopard genome, showing distinct genetic patterns between African and Asian populations. The analysis suggests that all African leopards should be considered a single subspecies due to abundant gene flow across Africa.
Researchers discovered that a growth factor, BMP11, drives the development of male water strider's long legs and fighting behavior. Knocking out this gene in males reduced leg size and aggression, highlighting its role in hyperallometry.
A University of Helsinki study of 9,000 dogs found that fearfulness is a key factor in aggressive behavior, with fearful dogs more likely to behave aggressively. The study also identified breed differences, with certain breeds exhibiting higher levels of aggression.
Researchers found that accumulation of unfavourable environmental factors increases the risk of polytoxicomania, a form of multiple drug use. The study identified use of cannabis before 18, physical and sexual abuse, migration, and growing up in a big city as major risk factors.
Researchers found that Eastern and Western house mice developed identical genetic changes to cope with cold temperatures, building bigger nests and growing heftier. This study demonstrates the predictability of evolution in mammals, with implications for understanding human evolution.
Researchers analyzed Lake Victoria cichlid genomes to identify genes contributing to adaptive radiation and species-specific adaptations. The study found evidence of selective sweep events and preexisting genetic variation underlying these processes.
Researchers at the University of California, Irvine have developed a new genetically engineered mouse model that mimics the most common form of late-onset Alzheimer's disease. The model, which embodies the remaining 95% of cases, holds promise for understanding causes of the disease and developing new treatments.
A study published in PNAS found that zebra finches have a low-density lipoprotein receptor gene with key domains missing, allowing them to carry high levels of good cholesterol while avoiding high cholesterol-related diseases. This genetic adaptation may hold clues for improving cardiovascular disease treatment.
Researchers have identified a genetic risk gene relevant to childhood OCD, which could help improve treatment options and diagnose youth earlier. The study used saliva samples from over 5,000 children and youth, comparing them to participant responses on obsessive-compulsive traits.
An international team found a strong genetic link between the shape of our face and brain, with 76 overlapping locations. However, this connection does not predict behavioral traits or risk of conditions like Alzheimer's disease.
A University of Colorado Boulder-led research team found the Iberá Seedeater, an endangered songbird, used genetic shuffling instead of new mutations for speciation. The bird's unique behavior keeps it apart from closely related species.
A new study finds that female choice regarding mate traits drives the emergence of new species in Iberá Seedeater songbirds. The study reveals pre-mating isolation as a powerful force in maintaining reproductive barriers between co-occurring species, leading to rapid speciation.
A recent study by McGill University researchers has mapped gene signatures to functional processes across the human brain, revealing key insights into cognitive and affective processes. The findings suggest that specific genetic signals are linked to attention and memory, while others are associated with emotions and fear.
A mouse study suggests that intense behavioral training before symptoms develop can delay the onset of Rett syndrome, a devastating neurological disorder. The training improved memory loss and motor control decline in mice with the genetic disorder.
A recent study suggests that inherited behaviors and traits appearing during adolescence, such as depression and neuroticism, can increase the risk of adult cannabis use. The research analyzed data from over 20,000 adolescents and found a small portion of the risk was attributed to genetic effects on these traits.
Researchers at Greenwood Genetic Center have identified cholesterol accumulation as a key contributor to the symptoms of genetic movement disorders, including seizures and balance issues. The study provides new hope for treatments targeting cholesterol accumulation, such as the drug 2-hydroxypropyl-beta-cyclodextrin, which showed signi...
Researchers at Stanford University developed a new technique to compare genetic differences between humans and chimpanzees, revealing significant disparities in the expression of genes SSTR2 and EVC2. This study provides insight into human evolution and potential causes of neuropsychiatric diseases.
Researchers have found genetic variants increasing ADHD risk and aggressive behavior in children, shared with the general population. These variants affect aggression in both children with and without ADHD, highlighting a complex interplay between genetics and environment.
Researchers at Mount Sinai Hospital have identified a new molecular driver of frontal circuit maturation that is essential for cognitive function. By selectively suppressing communication via nicotinic receptors in the frontal circuit, attention deficits caused by Fragile X syndrome can be prevented in animal models.
Researchers found that people with ADHD combined with disruptive behavior disorders share 80% of genetic variants associated with aggressive behaviors. The study identified a genomic segment in chromosome 11 that increases the risk of having both ADHD and DBD.
A new study published in eLife found that combining healthy lifestyle interventions with cholesterol-lowering medications yields the greatest benefits to heart health. Healthy lifestyles, including exercise and a balanced diet, can lower LDL cholesterol and increase HDL cholesterol, reducing the risk of heart disease.
Researchers identified three mechanisms that promote napping and found many genes also regulate sleep. The study linked napping to cardiometabolic health concerns, suggesting personalized recommendations may be needed.
A massive study of brain scan and genetic data from over 12,000 people reveals how a genetic disposition toward risky behavior is embodied in the brain. The research found associations between risk-taking and lower levels of gray matter in many brain regions, including the amygdala, hippocampus, and cerebellum.
A rare genetic syndrome caused by mutations in the gene SATB1 has been identified, characterized by neurodevelopmental delay, intellectual disability, and muscle tone abnormalities. Variations in the gene lead to different levels of protein activity, resulting in varying symptoms and severity.
A new mouse model created by researchers at the University of Bonn reveals that GPI anchor deficiencies, a group of rare diseases, are caused by impaired transmission of stimuli at brain synapses. The mice exhibited cognitive deficits, altered social behavior, and increased susceptibility to epilepsy, mirroring human symptoms.
Noncognitive skills, distinct from cognitive abilities, significantly impact educational attainment and life outcomes. The study identified 157 genetic locations related to these skills, which contribute equally to the heritability of educational attainment as cognitive ability.
A study from Cardiff University found that more than half of individuals with certain genetic conditions had significant autistic symptoms, despite not meeting formal diagnostic criteria. The research emphasizes the need for an individualized approach to assessing the needs of people with genetic conditions.
A new study decodes the molecular diversity of neurons in the zebrafish retina, identifying at least 32 different types of retinal ganglion cells. These cell types are linked to specific functions and behaviors, shedding light on how the brain processes visual stimuli.
Researchers analyzed gene expression in the brains of thousands of individual honey bees to find consistent differences between foragers and egg-layers. The study identified 15 transcription factors that explained behavioral differences, suggesting changes in these genes can lead to strikingly different behavior.
A new study assesses the implications of genetic testing for marketing strategy and research, highlighting potential uses and misuses of genetic data. The authors raise concerns about unique features of genetic data, including individual identification and predictive power, that may threaten consumer autonomy and privacy.
A recent study by researchers at UC Riverside suggests that olfaction may play an important role in motivating mammals to engage in voluntary exercise. The study found genetic differences in the olfactory system between high-runner mice and control lines, which made them perceive smells differently.
A study by German Primate Center found that coppery titi monkeys in Peru exhibit genetic monogamy, with none of the 18 offspring examined not sired by their social father. This suggests that mate choice is successful enough to outweigh potential genetic costs of infidelity.
Scientists have identified two paralogous androgen receptor genes that control social status in African cichlid fish, shedding light on the molecular basis of social hierarchy. These findings suggest independent mechanisms for regulating coloration and behavior, providing a framework for studying human social dominance.
A recent study at the University of Helsinki found that brainstem neurons play a crucial role in controlling both normal behaviour and misbehaviour in mice. The researchers discovered that faulty gene regulation can lead to behavioural abnormalities such as hyperactivity and attention deficit. The study provides new insights into the d...
Researchers found connections between autism types and abnormalities in parvocellular oxytocin neurons, which regulate platonic love and sociability. The study could fuel the development of autism therapies targeting disease symptoms spurred on by these brain cells.
A recent study has identified genetic variants associated with reproductive success, which may provide insights into the biology of fertility and infertility. The research found that diverse biological mechanisms contribute to reproductive success, implicating both neuroendocrine and behavioral influences.
Researchers create genetic sensors that can detect gene activity, not just presence, using CRISPR-Cas13 system. This innovation has potential for biotech applications, including therapeutics and diagnostics.
A study by Megan Carey and Catarina Albergaria found that altered cannabinoid signalling impairs learning in mice. However, this was not due to direct effects on neural plasticity, but rather the reduced activity levels of the mutant mice. Restoring behavioral state through exercise fully restored learning abilities.
Researchers from the University of Minnesota and Wildlife Institute of India found that large male lion coalitions consist mainly of brothers and cousins, while pairs of unrelated males also team up for better territory and mate acquisition. This study provides new insights into male cooperation among lions.
Researchers discovered a distinctive supergene in fire ant colonies determining young queen behavior, leading to new pest control methods. The study also found aggressive behavior towards queens without the supergene.
A DNA study reveals that scimitar-toothed cats were highly skilled hunters with good daytime vision and complex social behaviors. They had genetic adaptations for strong bones, cardiovascular systems, and endurance running, suggesting a pack-based hunting style.
Researchers have identified STAT3 as an important factor in emotional reactivity, establishing a link between the immune system, serotonergic transmission, and affective disorders. STAT3 deficiency reduces emotional reactivity in mice, suggesting its role as a molecular mediator in regulating emotional behavior.
Researchers found that adult wolves form individualized social bonds with their human handlers and display attachment-like behaviors when separated. These findings suggest that the evolution of dog-human attachment may be linked to the common ancestor's social system.
A University of Cincinnati researcher is conducting a study on pharmacogenomics and opioid addiction. The goal is to identify genetic markers associated with OUD and compare them between patients who have and don't have the condition.
Researchers have made a groundbreaking genetic discovery that sheds light on the cause of rare nerve disorders, including Rett syndrome. The study found two new mutations in the KIF1A gene to be responsible for these conditions.
Researchers have identified five genes associated with the different visual mating preferences of two tropical butterfly species. These genes are linked to the processing of visual information during courtship, without affecting perceptions of other aspects of the environment. This study provides insights into the evolutionary changes ...
A NIH-funded study identified neuronal abnormalities in cortical cells from individuals with 22q11.2 deletion syndrome, a genetic disorder associated with mental illnesses and developmental delays. The study suggests that overexpression of the DGCR8 gene and exposure to certain antipsychotic drugs can restore normal cellular functioning.
Researchers found that people with a genetic deletion syndrome are more excitable and experience abnormalities in calcium signaling, leading to an increased risk of developing schizophrenia. The study identified a single gene, DGCR8, as the main player in these cellular defects.
Scientists have deciphered two axes of brain organization, mainly determined by genetic factors, which reflect functional hierarchies from basic capabilities to complex skills. These findings provide insight into the evolution of brain structure and its relationship with genetic and environmental factors.
Researchers at Princeton University have discovered a small molecule named Streptosactin, which exhibits fratricidal activity in the human microbiome. This is the first time a small molecule has been found to kill its own kind.
Researchers found that individuals with a genetic risk for Alzheimer's disease exhibit impaired path integration, a cognitive ability essential for spatial navigation. The study suggests that grid cell activity in the entorhinal cortex plays a crucial role in this process, and may serve as a potential biomarker for early diagnosis.
Researchers found that a mutation in a tRNA gene can disrupt brain function and behavior, leading to imbalances in excitatory and inhibitory neurotransmission. This imbalance has been implicated in numerous neurological diseases, including epilepsies and autism spectrum disorders.
Research using fruit flies found that certain stationary patterns trigger the perception of illusory motion. The brain's motion-detecting neurons play a key role in this phenomenon, driven by imbalanced responses to stationary edges.
A study found that a specific genetic variation associated with communal behavior in non-human animals also affects human romantic relationship dynamics. Individuals with this variation reported higher levels of affection, fewer negative feelings, and improved relationship adjustment.