Research on the structure and workings of the human brain. Covers prenatal brain development, structural changes in disease, gray and white matter, and brain stimulation.
Researchers have successfully controlled a dexterous robotic hand using noninvasive EEG-based Brain-Computer Interfaces (BCIs) for individual finger movements. The study demonstrates real-time brain decoding and motor imagery control, paving the way for potential applications beyond basic communication to intricate motor control.
The study identifies the brain circuit controlling associations between stimuli and allows for indirect associations. The amygdala plays a crucial role in linking olfactory and taste stimuli.
Researchers used advanced neuroimaging and the Julich-Brain Atlas to identify specific brain networks linked to psychopathy, finding reduced volumes in multiple regions including basal ganglia, thalamus, and cortex. This study advances research on neuropsychobiological correlates of aggression.
Researchers have discovered that multimodal pain integration in the brain significantly enhances overall pain perception when participants are instructed on how to perceive the pain. The precuneus region of the brain plays a vital role in integrating pain information into a cohesive and intensified pain experience.
Researchers discovered that a lack of sleep affects how people with migraines process pain signals in the brain. This can lead to increased sensitivity and severity of migraine symptoms, highlighting the importance of adequate sleep for migraine management.
Researchers at Uppsala University have created a model of human nerve tissue using 3D printing, enabling the testing of new drug treatments in a lab environment. This innovation allows for more precise medicine and could potentially lead to improved treatment options for ALS patients.
Researchers at UC Davis developed a brain-computer interface that translates neural activity into speech in real time. The technology allows individuals with ALS to communicate more naturally and inclusively, with 60% of synthesized words intelligible to listeners.
Researchers have identified a specific group of neurons in the brain responsible for suppressing binge drinking behavior. The discovery may lead to new therapeutic targets for treating alcohol dependency and related health challenges.
Researchers found that transcranial magnetic stimulation (TMS) can alleviate some autistic behaviors and improve mental flexibility by reducing neural rigidity. The study's results provide a biological explanation for the coexistence of diverse behavioral traits in ASD.
The study reveals that white matter microstructure in infants' brains between 3-9 months predicts their emotional development. Infants with certain brain patterns are more likely to exhibit negative emotions or improved self-soothing abilities.
Researchers at Aarhus University and University of Oxford used a novel neuroimaging method to show that the brain dynamically reconfigures its organization in response to auditory stimulation. This discovery opens new possibilities for studying brain responses to music, consciousness, and other phenomena.
A new brain training game has shown promise in treating nerve pain, with participants experiencing significant reductions in pain and comparable relief to opioids. The PainWaive technology uses EEG headsets to track brain activity and respond in real time, providing a potential non-invasive alternative for chronic pain management.
MIT researchers developed a new hypothesis for how astrocytes contribute to memory storage, proposing that they encode memories through gradual changes in calcium flow patterns. This information is conveyed to neurons via gliotransmitters released at synapses connected to astrocyte processes.
Ion channels can 'remember' previous signals, leading to changes in the receiving neuron that last for hours or days. This collective memory can accumulate over time, reducing communication between neurons and contributing to lifelong learning.
A comprehensive analysis reveals how brains generalize learning from previous experiences to new scenarios, mapping neural pathways from hippocampus to cortex. The study's findings highlight the critical role of the hippocampus and prefrontal cortex in cognitive generalization.
A new technique using focused sound waves and microbubbles has shown great promise in treating debilitating brain lesions called cerebral cavernous malformations. The approach has halted the growth of lesions almost entirely, offering a potential paradigm shift in treatment.
Preliminary research suggests that long working hours can induce neuroadaptive changes in the brain, particularly in areas associated with emotional regulation and executive function. The study found increased brain volumes in regions such as the middle frontal gyrus, which is involved in attention and problem-solving.
A study published in Alzheimer's & Dementia found that learning one's Alzheimer's risk can decrease negative emotions like depression and anxiety, but also leads to decreased motivation for maintaining healthy lifestyle changes. Researchers emphasize the importance of personalized disclosure processes to sustain healthy behaviors.
Researchers at Korea University found a link between internal bodily awareness and making decisions aligned with group consensus. This connection was mediated by brain activity states associated with self-referential processing and internal attention.
Scientists develop brain-computer interface that allows users to design distinct tactile experiences for different objects, enabling them to guess the object by sensation alone. The study represents an important step towards creating a neuroprosthetic that feels pleasant and intuitive to use.
A team of researchers used machine learning to analyze changes in astrocyte cells' structure, shedding light on heroin addiction and relapse. The study, published in Science Advances, found that specific subpopulations of astroglia exhibit more pronounced morphological changes during drug use.
The MyoStep project represents a significant advancement in pediatric mobility aids for children with cerebral palsy, addressing motor impairments that restrict participation in physical activities. The soft power suit provides a lightweight, discreet solution tailored to fit seamlessly into the lives of children and their families.
A harmful form of tau protein directly damages blood vessels in the brain, leading to inflammation and weakening the brain's protective shield. The discovery highlights the importance of focusing on early neurovascular changes mediated by tau to prevent or slow down damage to the blood-brain barrier.
Dr. Seymour Reichlin's remarkable career spanned five decades, marked by scientific excellence, mentorship, and generosity. His influence on neuroendocrinology has been profound, with ongoing contributions at age 100 revealing new insights into Alzheimer's disease and ecstatic mysticism.
Research from the University of Oklahoma suggests that women with adequate iron levels in their blood perform better on cognitive tasks during menopause. Having enough iron does not necessarily mean accumulating more iron in the brain, which is a risk factor for neurodegenerative diseases like Alzheimer's.
New research reveals that bird species with hard-to-get tree cavities have evolved heightened aggression in females. The study found a set of genes consistently altered in the brains of these birds, mirroring molecular similarity across lineages.
Researchers developed a brain decoder to restore communication between the brain and spinal cord, allowing for rehabilitation and potentially restoring movement. The decoder used electroencephalography to predict movement intention, outperforming previous methods.
A new study found that staying active through moderate-to-vigorous physical activity is associated with significantly better processing speed, working memory, and executive function in older adults. Even small changes to daily activities can have big impacts on brain health.
A recent study used AI to discover that phosphoglycerate dehydrogenase (PHGDH) is a causal gene for spontaneous Alzheimer's disease. The researchers found that altering PHGDH expression levels can significantly impact the progression of the disease, suggesting a novel therapeutic target.
The World Sleep Society releases recommendations on wearable sleep trackers, providing clear guidelines for consumers, clinicians, researchers, and manufacturers. Key takeaways include choosing a device suitable for individual use cases and focusing on fundamental sleep measures rather than specific stages of sleep.
Mind blanking is a common experience characterized by lapses in attention, memory issues, and cessation of inner speech. Studies have shown that it's associated with specific neural signatures and changes in arousal levels, leading to malfunctions in key cognitive mechanisms like memory and language.
The Simons Collaboration on Ecological Neuroscience (SCENE) is a 10-year program that will support projects aiming to uncover how the world shapes representations in the mind and brain. By integrating sensory and motor information, researchers hope to discover fundamental principles of cognition applicable across species.
A study published in Neurology found that metabolic syndrome is associated with a higher risk of young-onset dementia. Researchers identified nearly two million people between the ages of 40 and 60 who had a health check-up, and found that those with metabolic syndrome were more likely to develop dementia, including Alzheimer's disease...
A new study reveals promising progress toward predicting how patients with major depressive disorder will respond to antidepressant medications. Brain connectivity patterns were found to significantly improve predictions of treatment response across two large, independent clinical trials.
Researchers at Trinity College Dublin have found that the brain forms memories of cold experiences and uses them to control metabolism. The discovery may lead to new treatments for conditions such as obesity and cancer, which are influenced by thermoregulation and metabolism.
A study published in PLOS Biology found that individuals who receive dynamic facial-expression feedback from an avatar's face tend to gamble more than those receiving real human feedback. The amygdala plays a key role in this facilitation, with increased valuation of uncertainty contributing to increased risk-taking behavior.
Common prescription medications can disrupt sterol biosynthesis, potentially causing developmental disorders. The editorial highlights the need for mandatory sterol biosynthesis screening in clinical practice.
Research found that adolescents who slept longer performed better at cognitive tests, with those sleeping 7-25 minutes more performing better. The study also found differences in brain volume and structure between the groups.
A team of researchers developed Lp-Convolution, a novel method that uses multivariate p-generalized normal distribution to reshape CNN filters dynamically. This breakthrough improves the accuracy and efficiency of image recognition systems while reducing computational burden.
Two brain proteins, Imp and Sdc, play a crucial role in preventing seizures by regulating neuronal growth and brain circuit development. Reducing either protein can lead to seizure-prone behavior in flies, highlighting their importance in seizure regulation.
Researchers found that the brain prioritizes more important items, representing them with higher precision and lower resolution for less important ones. The frontal cortex communicates with the visual cortex to decide which item receives more working memory resources.
A clinical trial found that using EEG to monitor consciousness safely reduced anesthetic use in children, resulting in quicker recovery, reduced delirium, and lower healthcare costs. The study also showed a significant reduction in pediatric anesthesia emergence delirium.
Researchers investigated how brains process language during real-life conversations, employing AI to analyze neural activity and linguistic features. They found that speaking and listening engage widespread networks of brain areas in the frontal and temporal lobes, with highly specific patterns changing depending on words and context.
A team of researchers, led by Jean-Paul Noel, has discovered that the brain's motor area largely coincides with the onset of intention. The study used a brain-machine interface to separate intentions from actions in a paralyzed participant, revealing a compressed temporal binding between intention and action.
Dr. Rhonda Winegar investigates the effectiveness of music therapy in supporting neurological care, including its ability to reduce anxiety and depression in Alzheimer's patients. Her research also highlights its potential to regulate heart rate and blood pressure, as well as improve motor function in individuals with Parkinson's disease.
A new study has found that older age is linked to higher levels of three dementia biomarkers in the blood. Researchers also discovered sex differences in biomarker levels, with female participants having higher levels of glial acidic proteins.
Researchers at UCL developed a new scoring system, CAR, to identify patients with narrowed carotid arteries who can be effectively treated with optimised medical therapy. The study found low rates of recurrent strokes and heart attacks among patients treated with medication alone.
A novel cannula delivery system allows repeated, nondisruptive delivery of imaging agents to the mouse brain during long-term multiphoton microscopy. This innovation enhances longitudinal studies on brain function, disease progression, and potential treatments.
The human brain can learn to suppress early visual processing of distracting stimuli, such as roadside billboards, after repeated exposure. This learned suppression enhances attention to relevant stimuli and improves performance in tasks that involve frequent distractions.
The Feihe Pediatric Brain Development Research Initiative at Boston Children's Hospital aims to improve brain development through genetic, nutritional, and environmental factors. The initiative has awarded funding to seven researchers working on projects related to prenatal and postnatal brain development.
A new brain imaging study found that age and brain shape significantly impact the strength of connections between olfactory brain regions in dogs. Younger dogs and those with elongated brains had stronger functional connectivities, while older dogs and rounder-headed individuals performed worse in smell tests.
A team of researchers at UCL has identified key brain regions essential for logical thinking and problem-solving. They used lesion-deficit mapping to study patients with brain lesions caused by stroke or tumors and found that damage to the right frontal lobe impaired reasoning skills.
A new global study found common genetic factors contributing to drug resistance in focal epilepsy, affecting 20 million individuals. Researchers identified specific genetic variants in CNIH3 and WDR26 genes associated with a higher risk of drug-resistant epilepsy.
Researchers found that SIRT2, a previously unknown enzyme, plays a key role in excessive GABA production associated with Alzheimer's disease. This process leads to brain inflammation and memory impairment. By targeting SIRT2, scientists can selectively block its harmful effects on memory without affecting other brain functions.
The research aims to bridge the translational gap between animal and human studies, exploring how obesity impacts decision-making around food. The team will measure brain chemical activity while participants consume sugary drinks and complete emotion-related tasks.
A new study by Martin-Luther-University Halle-Wittenberg found that brain stimulation can influence decisions, making choices faster with anodal stimulation and slower with cathodal stimulation. The research used transcranial direct current stimulation to activate or inhibit specific brain regions.
Researchers evaluated different types of Glasgow Outcome Scale Extended (GOSE) scores among US trauma center patients. They found that GOSE-All scores capture the combined effect of brain and extracranial injuries, while GOSE-TBI scores exclude extracranial injury effects.
Natalia S. Rost, a Boston-based stroke neurologist, has been elected as the new president of the American Academy of Neurology. With over 25 years of involvement in the AAN, Rost is renowned for her expertise in vascular neurology and big-data science applications to personalized clinical outcome prediction in stroke.
A novel brain study uncovers the critical role of the HDAC5 enzyme in regulating gene expression and neuronal activity, which can trigger relapse in individuals with substance use disorders. The study highlights a new molecular target for developing novel treatments to reduce relapse risk.
Researchers at The University of Texas at San Antonio are working on a new AI tool to improve lives after brain injury. They plan to analyze data from 3,000 veterans and develop an interactive dashboard for clinicians to use, providing insights that could revolutionize treatment.