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The cold virus ‘hides’ and multiplies in the tonsils and adenoids, even in people without symptoms

A study reveals that the rhinovirus, causing the common cold, can infect immune cells in the tonsils and adenoids, remaining dormant for extended periods without symptoms. This persistence allows for unexpected transmission and triggers new outbreaks, particularly among children, who are a primary mode of transmission to grandparents.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalJournal of Medical Virology·DateApr 16, 2026

Comprehensive analysis of imaging and pathological features in 20 cases of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma: a retrospective study

A retrospective study of 20 cases of pulmonary MALT lymphoma found characteristic HRCT features such as air bronchogram and bronchiectasis, predominantly in the left upper lobe. Pathologically, tumors exhibited monocytoid and centrocyte-like cells with minimal atypia and B-cell markers CD20 and CD3.

SourceNational Center for Respiratory Medicine·JournalJournal of Thoracic Disease·TypeObservational study·DateApr 9, 2025
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Wyss Institute’s iNodes team receives ARPA-H Sprint for Women’s Health award to advance the first implantable immune organs to treat ovarian cancer

The Wyss Institute's iNodes team has been awarded an ARPA-H Sprint for Women's Health to develop implantable immune organs for treating ovarian cancer. The iNodes concept is based on the formation of lymphoid organs in tumors, which can be reprogrammed to attack cancer cells and retain a long-term immune memory.

SourceWyss Institute for Biologically Inspired Engineering at Harvard·DateNov 12, 2024

Wearable, inexpensive robotic sleeve for lymphedema treatment

Researchers developed a soft robotic sleeve controlled with a microfluidic chip that reduces treatment cost, weight, and power consumption for lymphedema treatment. The device promotes fluid flow in the lymphatic system by sequentially inflating balloons and pushing fluid upwards.

SourceAmerican Institute of Physics·JournalBiomicrofluidics·DateMay 5, 2022

New oncogenic mechanisms in lymphoma via extracellular vesicles discovered

Researchers have identified a new mechanism of action for extracellular vesicles in the development and progression of lymphomas. sPLA2 secreted by tumor-associated macrophages degrades EV-derived phospholipids, enhancing EV function and inducing vital phenomena. This discovery may lead to new drug targets for cancer treatment.

SourceJapan Science and Technology Agency·JournalCell Metabolism·TypeExperimental study·DateMar 28, 2022
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Scientists gain unexpected insight of lymphatic vessels in the heart

Researchers at UNC School of Medicine discovered that VE-cadherin is a key player in the maintenance and function of lymphatic vessels in the heart. However, they found that loss of these vessels was not associated with decreased heart function, contradicting previous assumptions.

SourceUniversity of North Carolina Health Care·JournalCirculation Research·TypeExperimental study·DateJan 13, 2022

Hobit turns immune cells into killers

Researchers at the University of Würzburg have found that innate lymphoid cells can specialize into killer cells that recognize and kill tumour cells. The study reveals a new transcription factor, Hobit, drives this specialization process.

SourceUniversity of Würzburg·JournalNature Immunology·TypeExperimental study·DateAug 30, 2021

Shortcut for dendritic cells

Researchers at ETH Zurich have discovered that dendritic cells can migrate more quickly to lymph nodes via a newly found pathway during inflammation. This route allows them to bypass the slow and energy-intensive process of entering capillary vessels, enabling faster immune activation and response.

SourceETH Zurich·JournalJournal of Experimental Medicine·DateMay 17, 2021
GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Immune cells discovered in the lungs improve virus defense

Researchers at the University of Basel have identified immune cells resident in the lungs that persist long after a bout of flu, improving the immune response to reinfection by different strains. The discovery could lead to longer-lasting vaccinations against quickly-mutating viruses.

SourceUniversity of Basel·JournalScience Immunology·DateJan 8, 2021

New prognostic markers for colon cancer identified

Researchers have identified isolated lymphoid structures (ILSs) as novel prognostic markers for metastatic colorectal cancer. ILSs, which are integral to the immune system, orchestrate multifaceted immune responses and can predict improved clinical outcomes in patients.

SourceMedical University of Vienna·JournalCancers·DateNov 11, 2020

Innate lymphoid cells regenerate within lung

Researchers have generated a single-cell atlas of mouse innate lymphoid cells in the lung, discovering a pool of local progenitors that can generate mature ILC2s. The study reveals the complexity of ILC2 functions and their developmental relationships, shedding light on how they contribute to immune defense and inflammatory diseases.

SourceMax Planck Institute of Immunobiology and Epigenetics·JournalImmunity·DateSep 30, 2020

Immunology: Tonsils as a testbed

A team of scientists at Ludwig-Maximilians-Universität München has isolated immune cells from human tonsils obtained following routine surgery, allowing them to analyze the immune response and test anti-inflammatory agents. The new culture system enables researchers to study human lymphoid tissue under physiologically relevant conditions.

SourceLudwig-Maximilians-Universität München·JournalEBioMedicine·DateFeb 28, 2020

Study finds cellular processes controlling the formation of lymphatic valves

Researchers at the University of South Florida have identified key signaling pathways involved in lymphatic valve development and maintenance. The study suggests targeting these pathways may one day be a viable therapy for patients with lymphedema, a debilitating disease characterized by chronic swelling and fluid buildup.

SourceUniversity of South Florida (USF Health)·JournalCell Reports·DateAug 27, 2019
Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Study reveals how immune cells target different tissues

A study published in Immunity reveals that T regulatory cells have tissue-specific receptors and adaptations to localize themselves in specific tissues. This discovery could lead to the development of targeted therapies for autoimmune diseases by manipulating therapeutic T cells to specific locations in the body.

SourceWellcome Trust Sanger Institute·JournalImmunity·DateFeb 5, 2019

New way to regenerate hearts after a heart attack

Researchers have identified how a new treatment in mice can regenerate the heart after a heart attack by promoting growth of lymphatic vessels and clearing immune cells. This approach showed significant reduction in damaged heart muscle and improved recovery of pumping function.

SourceBritish Heart Foundation·JournalJournal of Clinical Investigation·DateJul 9, 2018
Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

COPD-associated inflammation halted in model experiment

Researchers at Helmholtz Zentrum München discovered a previously unknown pathogenic mechanism underlying COPD. By targeting the oxysterol pathway, they were able to prevent iBALT formation and immune cell migration, halting inflammation in an experimental model.

SourceHelmholtz Munich (Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH))·JournalEMBO Molecular Medicine·DateMay 3, 2018

Timing is everything, to our genes

A Salk Institute study has discovered that nearly 80 percent of genes exhibit daily fluctuations, with the most rhythmic genes peaking in early morning and late afternoon. This finding has significant implications for understanding circadian disruption's impact on diseases such as depression and heart disease.

SourceSalk Institute·JournalScience·DateFeb 8, 2018
Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Ongoing HIV replication replenishes viral reservoirs during therapy

A new study funded by NIH suggests that ongoing HIV replication in lymphoid tissues maintains stores of the virus, a prerequisite for achieving a cure. Current ART regimens cannot eliminate persistent viral reservoirs, but sequencing data shows continued evolution over time without accumulating drug-resistant mutations.

SourceNIH/National Institute of Allergy and Infectious Diseases·JournalNature·DateJan 27, 2016
Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Blood T cells are resistant to HIV's primary death pathway

Blood T cells are resistant to HIV's primary death pathway, but not lymphoid tissue T cells. The researchers suggest that studying lymphoid tissue T cells could lead to a better understanding of the virus and potentially new treatments.

SourceGladstone Institutes·JournalCell Host & Microbe·DateOct 14, 2015

Restoring natural immunity against cancers

Researchers at Institut Pasteur successfully inhibit enzyme DPP4 to increase T lymphocyte infiltration into tumors, leading to efficient cancer cell destruction. This innovative treatment combines with existing immunotherapies to eradicate tumors in mice.

SourceInstitut Pasteur·JournalNature Immunology·DateJun 17, 2015

New function for a well-known immune messenger molecule

Researchers at ETH Zurich discovered that IL-7 enhances lymphatic vessel drainage, a crucial function that could improve lymphedema treatment outcomes. This finding may help prevent or alleviate fluid accumulation and tissue swelling in patients with compromised lymphatic systems.

SourceETH Zurich·JournalBlood·DateAug 26, 2013

Study evaluates procedures for diagnosing sarcoidosis

A new study has compared the effectiveness of two diagnostic procedures for sarcoidosis: endosonography and bronchoscopy. The researchers found that endosonography resulted in a significantly higher diagnostic yield, detecting granulomas more often than bronchoscopy.

SourceJAMA Network·JournalJAMA·DateJun 18, 2013
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Sniffing immune cells

Researchers at IST Austria found that immune cells follow gradients of guidance cues, which are bound to the tissue, to navigate through the skin. The cells use a mixed strategy, combining sensing of soluble and insoluble cues, to find their way back to lymphatic vessels.

SourceInstitute of Science and Technology Austria·JournalScience·DateJan 17, 2013

Tips from the American Journal of Pathology

Intestinal ischemia/reperfusion damages the intestine's lining, allowing bacteria to enter the bloodstream. Caveolin-1 modulates endothelial nitric oxide synthase activity to regulate innate immunity. Development of intestinal lymphoid follicles relies on dendritic cell recruitment.

SourceAmerican Journal of Pathology·JournalAmerican Journal Of Pathology·DateMay 7, 2010
Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Building the lymphatic drainage system

Researchers Norrmén et al identified Foxc2 and NFATc1 as key transcription factors in lymph vessel development. These factors work together to build lymph vessel valves, a critical aspect of the lymphatic drainage system.

SourceRockefeller University Press·JournalJournal of Cell Biology·DateApr 27, 2009

Can EUS elastography help distinguish benign from malignant tissue?

A multicenter study found EUS elastography to be highly sensitive and specific in distinguishing benign from malignant tissue, with a sensitivity of 92.3% for pancreatic lesions and 91.8% for lymph nodes. The technique may help characterize pancreatic masses after negative EUS-FNA and increase the yield of EUS-FNA for lymph nodes.

SourceWorld Journal of Gastroenterology·JournalWorld Journal of Gastroenterology·DateApr 15, 2009

New origin found for a critical immune response

Duke researchers found that a blood-derived lymph node dendritic cell type plays a key role in developing acute T-cell responses. This discovery challenges traditional views on dendritic cell function and has implications for vaccine science and autoimmune disease therapy development.

SourceDuke University Medical Center·JournalNature Immunology·DateMar 1, 2009

Heterotopic gastric tissue simulating acute appendicitis

A unique surgical case presented a patient with heterotopic gastric tissue simulating acute appendicitis. The inflammation from the gastric tissue caused localized pain and elevated white blood cell count. Removal of the inflamed lymph node containing the gastric tissue resolved the symptoms.

SourceWorld Journal of Gastroenterology·JournalWorld Journal of Gastroenterology·DateMay 20, 2008
Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Hormone may be new drug target for preventing lymphedema, tumor spread

Researchers identified a critical role for the hormone adrenomedullin in forming the lymphatic system, which could lead to new treatments for lymphedema. Targeting this hormone may also prevent cancer cells from spreading through lymphatic vessels.

SourceUniversity of North Carolina at Chapel Hill·JournalJournal of Clinical Investigation·DateDec 20, 2007

Front-line immune cells mature in four stages, study shows

Researchers at Ohio State University Comprehensive Cancer Center identified the four stages of natural killer cell maturation in secondary lymphoid tissue, such as tonsils and lymph glands. This discovery could lead to new therapies for cancer, infection, and immune deficiencies, advancing our understanding of the human immune system.

SourceOhio State University·JournalJournal of Experimental Medicine·DateApr 19, 2006

Discovery of T-cell 'traffic control' boosts new drug promise

Research discovers T-cell 'traffic control' system that prevents autoimmune disease and rejection of transplanted organs, promising new treatment for multiple sclerosis and transplant rejection. The system is controlled by a fat-like compound called S1P, which can be blocked with experimental drugs to prevent excessive T cell activity.

SourceUniversity of California - San Francisco·JournalNature Reviews Immunology·DateJul 14, 2005
Sky-Watcher EQ6-R Pro Equatorial Mount

Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.

JCI Table of Contents, November 14, 2003

Two independent studies successfully selected and expanded gene-corrected human stem cells using a novel drug-resistance gene. This breakthrough may be useful in human clinical trials of gene therapy for bone marrow transplantation settings. Additionally, upregulation of Irs2 promotes beta cell growth, survival, and insulin secretion, ...

SourceJCI Journals·JournalJournal of Clinical Investigation·DateNov 14, 2003

MCG researcher develops animal model for studying autoimmune disease

Dr. Pandelakis Koni has developed an animal model to study autoimmune diseases, including multiple sclerosis and type 1 diabetes, by selectively stopping the immune response. The mouse model allows researchers to understand how dendritic cells trigger the immune system and develop strategies to prevent autoimmunity.

SourceMedical College of Georgia at Augusta University·DateFeb 13, 2002
Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

UK researchers raise hopes of preserving fertility for women with cancer

UK researchers have made significant progress in preserving fertility for women with cancer by grafting ovarian tissue from cancer patients into mice, demonstrating safety and feasibility. The study has raised hopes for women who require immediate treatment or lack a partner, offering an alternative to embryo freezing.

SourceEuropean Society of Human Reproduction and Embryology·JournalHuman Reproduction·DateSep 26, 2001

New sensitive assessment method for the detection of vCJD

Researchers developed a highly sensitive immunoblot method to detect PrPSc in vCJD tissues, revealing its presence in lymphoid tissues and high concentrations in tonsil. The findings suggest new models for risk-management and highlight the need for further investigation into peripheral tissue transmission.

SourceThe Lancet_DELETED·JournalThe Lancet·DateJul 19, 2001

Change In HIV May Precipitate AIDS

Researchers have created a laboratory model of AIDS by infecting tonsil tissue with HIV. The model reveals that changes in the virus's properties lead to immune system deterioration and supports the idea that environmental factors contribute to AIDS development.

SourceNIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development·JournalNature Medicine·DateMar 12, 1998
Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.