Research that follows groups of people over time. Covers cancer-linked stroke, light exposure and health, neurodegeneration in athletes, and fertility-treatment risk.
A recent study by Children's Hospital Los Angeles showed that reprioritizing organ allocation led to better outcomes for children with PALF. The changes resulted in substantially decreased deaths on the pediatric waitlist, increased rates of liver transplant, and improved post-transplant outcomes.
Researchers at Karolinska Institutet have identified a new potential risk marker for cardiovascular disease in older women. Low levels of an anti-inflammatory antibody are associated with a higher risk of heart attack and coronary heart disease, independent of other known risk factors.
A new study reveals a significant association between COVID-19 and acute kidney disorders, including acute kidney injury, peaking during the second week after infection. Healthcare providers should closely monitor kidney function in COVID-19 patients with moderate to severe cases, particularly during the first few weeks after infection.
A recent study published in The American Journal of Clinical Nutrition found that over 80% of women are iron deficient by the third trimester of pregnancy. Despite being considered a high-resource setting, the study revealed alarming rates of iron deficiency among healthy pregnant women. This finding emphasizes the importance of routin...
A multinational study found that people with unmedicated mental illness are less likely to be vaccinated against COVID-19, with a 9% lower vaccination rate compared to the general population. Individuals with substance use disorder were also 16% less likely to receive the vaccine.
A study analyzing health data from 780 infants found that early signs of asthma can be predicted by observing dynamic symptom development during the first year. Genetic predisposition, air pollution, and infections were key risk factors contributing to the child's respiratory system adaptation.
Treatment-emergent nirmatrelvir resistance mutations were commonly detected in immunosuppressed individuals, but at low frequencies and transient nature. The study suggests a low risk for the spread of nirmatrelvir resistance in the community with current variants and drug usage patterns.
Children with medical complexity from rural areas are more likely to receive care at non-pediatric hospitals. The study emphasizes the importance of ensuring all hospitals can provide adequate care for these patients.
A cohort study found a significant association between maternal influenza infection during pregnancy and an increased risk of childhood seizures. The study suggests that maternal influenza may affect childhood neurological development, particularly for febrile seizures, but not epilepsy.
A recent cohort study found that prenatal exposure to COVID-19 during pregnancy did not increase the risk of autism screening in toddlers. The research suggests that maternal SARS-CoV-2 infection and pandemic-related exposure had no significant impact on autism positivity rates.
A new study found that genetic differences account for 60% of variation in food fussiness at 16 months and 74% by age 13. Environmental factors become more influential in later years.
The seasonal influenza vaccine was found to be safe in women with successive pregnancies, regardless of the interpregnancy interval and type of vaccine used. The study's findings support recommendations for vaccinating pregnant individuals or those who may become pregnant during the influenza season.
A cohort study of 1.5 million patients found that at-risk groups are disproportionately affected by denied claims for preventive services, perpetuating unequal access to high-value healthcare.
The study found that home discharge rates increased more for Hispanic compared to non-Hispanic white patients, highlighting the importance of considering differential outcomes in Medicare payment policies. These findings suggest the need for tailored approaches to address racial and ethnic disparities in joint replacement care.
Researchers found that cancer survivors with overweight or obesity are more likely to develop a second cancer, especially obesity-related ones. This study highlights the importance of promoting weight management and increasing awareness of second cancers among physicians and cancer patients.
Researchers identified known genetic variants for Alzheimer’s disease as risk factors for all-cause dementia and vascular dementia. The study also found a substantial genetic overlap with vascular dementia and cerebral small-vessel disease.
Exposure to negative news media about LGBTQ+ topics increases suicidal ideation intensity in the hours following, according to a longitudinal study. The findings have implications for research and intervention in sociopolitical and geographic contexts.
A new NIH-funded study found that children who experienced food insecurity during early childhood or whose mothers experienced it during pregnancy had a higher BMI and increased chance of developing obesity. Researchers explored how neighborhood food access affected child body mass index and obesity over time.
A retrospective cohort study of 3,389 patients with obesity found that semaglutide and liraglutide were associated with significant weight reduction at 1 year. The study suggests that persistent medication coverage, dosage, treatment indication, and patient sex are important factors in determining weight loss outcomes.
A single-center cohort study identified substantial overall survival disparity among racial and ethnic groups, with socioeconomic status contributing less than a third of the disparity. Tumor molecular features also played a significant role in the disparities found in colorectal cancer survival.
Researchers found an association between consuming foods with lower nutritional quality and a higher risk of cardiovascular diseases, particularly myocardial infarction and stroke. The study used the latest version of the Nutri-Score algorithm and included over 345,000 participants from seven European countries.
A Danish study reveals that only children and those with half- or step-siblings enter puberty significantly earlier than children with biological siblings. The study found a two-month difference in girls' pubertal timing and a smaller but still significant gap for boys.
A study published in Kidney International Reports identified mutations in the IFT140 gene as a potential cause of polycystic kidney disease in patients without a family history. The findings suggest that these patients may be underdiagnosed due to mild symptoms and atypical kidney characteristics.
A recent study in Sweden found a significant decline in both melanoma incidence and mortality among individuals aged 30-49. The causes of this downward trend are unclear but may be attributed to increased UV protection, public health campaigns, demographic changes, or advancements in melanoma treatment.
Researchers at the University of Copenhagen have identified a protein called OSER1 that influences longevity in various animals and humans. The discovery opens up possibilities for understanding age-related diseases and developing new drug targets.
A cohort study found no association between GLP-1 receptor agonist use and increased risk of suicide death or related disorders in patients with type 2 diabetes. The study included mostly patients with type 2 diabetes.
A new study funded by the National Institutes of Health found that consuming fish during pregnancy was associated with a lower likelihood of autism spectrum disorder (ASD) diagnosis, particularly in females. The study also found no significant association between omega-3 supplements and autism diagnosis.
A cohort study found that early childhood education is associated with social determinants of health in adulthood. The findings suggest that educational attainment is a key mechanism for promoting healthier communities and addressing health disparities.
This study found modestly increased risks of inflammatory bowel disease and bullous skin disorders in hospitalized patients infected with the Omicron variant. Booster vaccination mitigated long-term autoimmune sequelae risk.
A five-year study led by Tulane University is investigating a new medication to treat trichomoniasis. The research compares secnidazole with metronidazole, finding that one-dose treatment could offer better options for the infection, which affects 156 million people annually.
A new NIH-funded study found minor changes in youth mental health overall, but significant variations depending on age, race, gender, and pre-existing mental health. Children with clinically significant problems before the pandemic improved, while others experienced declines or no change.
A cross-sectional study of 170 former football players found a strong association between repeated head impacts and increased perivascular space volume, as well as worse cognitive test performance. The findings suggest that PVS volume may contribute to the link between RHI exposure and neurodegeneration.
A longitudinal cohort study found differential susceptibility and resilience for mental health problems during the pandemic associated with prepandemic mental health and sociodemographic characteristics. The study's findings have implications for recovery and may provide novel insights into causes of youth mental health problems.
A new study published in the American Journal of Clinical Nutrition found that pesco-vegetarian diets are associated with a lower risk of mortality and certain neurological conditions in elderly individuals. The study analyzed data from over 88,000 subjects and found that pesco-vegetarians had an 18% lower risk of death compared to non...
A cohort study found elevated depression and anxiety levels in unvaccinated people with COVID-19 diagnosis compared to before or without the virus. Vaccination was associated with lower incidence of mental illnesses after hospitalization for COVID-19.
A cohort study found that expanded child tax credit (ECTC) enacted substantially lowers food insecurity, whereas ECTC expiration significantly raises it. The monthly payment structure and lack of earnings requirements may play a crucial role in preventing food insecurity.
A study of 1,300 emerging adolescents found that higher parental technoference levels were associated with increased anxiety symptoms, inattention, and hyperactivity. The findings highlight the need for parents and emerging adolescents to discuss digital technology use and mental health as part of routine care.
A 1-year study found that continuous outdoor exposure with high sunlight intensity was associated with less myopic shift in children. Effective outdoor exposure patterns should be prioritized to prevent myopia in children.
A cohort study found that PTSD is a modifiable risk factor for a modest reduction in microvascular complications in veterans with comorbid PTSD and type 2 diabetes. The study suggests further research is needed to confirm findings in non-Veterans Health Administration settings.
A UK cohort study reveals that even low-risk alcohol consumption is linked to increased mortality among older adults with health-related or socioeconomic risk factors. The findings suggest that healthier lifestyles may play a role in the observed attenuation of mortality for wine drinkers and those who drink only during meals.
A cohort study found an association between cannabis-related disorder and the development of head and neck cancer. The study highlights the need for further research on the mechanism of this association and dose response to support evidence of cannabis use as a risk factor.
A cohort study found that childhood and adolescent depression symptoms were associated with impaired adult psychosocial functioning. The study highlights the importance of screening and monitoring children and adolescents for depression to inform policymaking regarding young adult mental health and psychosocial outcomes.
Researchers found that osteoporosis is independently associated with rapid leukocyte telomere length shortening over a 2-year period. A total of 233 subjects were enrolled in the study, and multivariable linear regression analysis indicated that only osteoporosis was significantly linked to LTL shortening.
A cohort study found that aspirin use was associated with a greater absolute reduction in risk of colorectal cancer among individuals with less healthy lifestyles. Lifestyle risk factors may help identify those with a more favorable risk-benefit profile for cancer prevention with aspirin.
A study found that city-level sugar-sweetened beverage taxes are associated with lower body mass index percentile among youth. Policymakers may consider implementing such taxes to prevent or reduce youth overweight and obesity, ultimately reducing chronic disease risk, particularly among children under 12.
Research at the University of Gothenburg shows that daily activities are insufficient to prevent strokes. Exercise in free time and active transportation significantly reduce stroke risk. The study suggests promoting public health policies encouraging physical activity to improve outcomes.
α-Synuclein pathology in asymptomatic stages is linked to NBM atrophy, leading to attention/executive impairment. MRI signatures can detect this pathology in memory clinic populations.
Researchers found that combining plasma p-tau217 and Aβ42/40 levels could predict early brain Aβ accumulation in people with subthreshold Aβ accumulation. These biomarkers may help screen participants for primary prevention trials.
Women with bilateral mastectomy have a greatly diminished risk of contralateral breast cancer, yet experience similar mortality rates as patients treated with lumpectomy or unilateral mastectomy. The study highlights the importance of considering long-term risks and benefits in breast cancer treatment decisions.
Community disadvantage status affects hospital stroke care services, with disadvantaged hospitals having lower certification rates. Hospitals in most advantaged communities show higher likelihood of becoming stroke certified.
A cohort study found that prenatal cannabis use was associated with several negative maternal health outcomes during pregnancy. The study emphasizes the need for further research on how different aspects of prenatal cannabis use may impact these associations.
A study published in BMC Medical Research Methodology reveals an increase in ectopic pregnancy prevalence and incidence during the period of electronic health record maturation. The research highlights the importance of using open cohort data to understand trends and reduce inequalities in health.
A cohort study found that a healthy prenatal dietary pattern was linked to reduced risk of autism diagnosis and social communication difficulties in offspring. Adherence to this dietary pattern was not significantly associated with reduced restrictive and repetitive behaviors.
A new study reveals that about two percent of the population develop autoantibodies against type 1 interferons, making them more susceptible to severe viral infections. The autoantibodies remain detectable in the blood for life and are associated with a compromised type 1 interferon system.
A meta-analysis of 35,000 children from eight European countries has found a robust link between exposure to green spaces and better lung function. Children living in greener neighborhoods had higher forced vital capacity (FVC) and forced expiratory volume in one second (FEV1), indicating improved airway function.
A retrospective cohort study found hormone-modulating therapy protected against Alzheimer's disease and related dementias in postmenopausal women with breast cancer. The protective effect varied by age and race, with greater benefit for Black women under 75.
A recent study published in Nature Medicine confirms the health benefits of a diet high in unsaturated plant fats, such as the Mediterranean diet. The research used lipidomics to measure diet-related fat changes in the blood and link them to disease risk.
A longitudinal cohort study found that telehealth availability has declined since the COVID-19 public health emergency ended, affecting mental health treatment facilities. The decline suggests a need for targeted policies to sustain telehealth access and ensure continued support for mental health care.
A cohort study found increased patient coinsurance in Medicare Part D's coverage gap and catastrophic coverage phases at age 65, associated with higher spending on T2D medications. This may lead to reduced diabetes medication utilization, increasing the risk of nonadherence and complications.
A large cohort study in Canada found an association between prenatal ambient PM2.5 exposure and increased cerebral palsy risk in offspring. Further research is needed to understand this association and potential biological pathways.