Articles tagged with Laboratories
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at UCI have discovered that sound waves can disrupt the safe operation of negative pressure rooms, a space designed to protect against deadly pathogens. They found that manipulating airflow using a specific frequency can cause malfunction and leakage of microbes.
A new study analyzed tumor biopsies from patients with newly-diagnosed germinal center B cell lymphoma and found that CREBBP mutations were associated with lower disease-free survival rates. The researchers identified CLMA as a practical tool to translate experimental findings into clinical applications.
Researchers evaluated modified CEUS using perfluorobutane for diagnosing hepatocellular carcinoma in high-risk patients. The study found no significant difference in sensitivity, specificity, or accuracy between modified CEUS and CT/MRI LI-RADS v2018.
The discovery pushes back the timeline of pre-Neanderthal hominins in Europe by 200,000 years, with the site yielding over 300 well-preserved footprints. The findings have significant implications for our understanding of human evolution and dispersal in the Middle Pleistocene.
A handheld diagnostic lab developed by UCLA researchers can fully automate pooled testing and detect multiple diseases, reducing costs and usage of scarce supplies. The technology can be easily manufactured, deployed, and performed at a doctor's office or mass testing sites, helping authorities prepare for future pandemics.
A study by Children's Hospital of Philadelphia researchers found that COVID-19 vaccination results in higher antibody concentrations compared to natural infection, providing robust protection for mothers during pregnancy. The study also suggests optimal vaccine timing can maximize the transfer of antibodies to babies.
The West Texas Pharmacology Core laboratory at TTUHSC will focus on two primary areas: drug development and pediatric cancer. The core aims to address obstacles in drug development, including limited pharmacology expertise for small biotech companies and low profitability for pediatric cancer drugs.
Researchers have identified a new gene, NUCL-1, in the transparent roundworm C. elegans, which is linked to human neurodegenerative diseases such as ALS and Alzheimer's. The discovery challenges recent theories on the role of nuclear structures in these disorders.
A higher urine-to-plasma urea ratio is associated with faster decline in eGFR and development of kidney failure in patients with common forms of CKD. This biomarker may improve risk prediction, particularly in low-cost, easily measurable assays.
Researchers at Jacobs University have found that a compound in coffee, 5-caffeoylquinic acid, can inhibit the interaction between the SARS-CoV-2 spike protein and the ACE-2 receptor, potentially providing protection against COVID-19. The study's findings suggest that regular coffee drinkers may be less likely to contract the virus.
The SwRI experiment helped predict the effects of NASA's DART impact on asteroid Dimorphos. The study assessed ejecta momentum enhancement created by the space probe's collision, measuring a 3.4-fold increase in momentum transfer.
Research found a hospital code response team arrives at least one minute quicker and leads to better patient outcomes with smartphone emergency code notification systems. The study used a secure texting system that connected with electronic medical records, reducing conventional methods' average delay of 78 seconds.
A Tel Aviv University study reveals that the Israeli shoreline is contaminated with more than two million tons of microplastics, with Tel Aviv and Hadera beaches being the most polluted. The researchers warn that exposure to microplastic waste is unavoidable and poses a risk to human health.
A Tel Aviv University study shows that pressure chamber therapy can improve social skills and reduce neuroinflammation in the autistic brain. The treatment, which involves high-pressure chambers with oxygen enrichment, was found to increase blood and oxygen supply to the brain, leading to improved brain function and social behavior.
McCullough's research advances the field of cardiovascular science, with a primary focus on sex differences in stroke. Her work has led to significant discoveries about cell death pathways during ischemic insults.
Researchers found that centenarians have a lower epigenetic age than expected, suggesting slowed biological aging. The study used four epigenetic clocks based on small CpG sites to reveal these differences.
A new experimental device has been developed to generate temperature gradients on a microtiter plate, allowing for the simultaneous testing of different temperatures. This innovation solves a common challenge in biological studies of living cells, unlocking new possibilities for studying cellular growth and development.
A recent poll reveals that 48% of people aged 50-80 have purchased at least one home health test, including COVID-19 and DNA tests. Notably, 82% of older adults express interest in future medical tests at home, while 90% agree to share results with their healthcare provider.
Researchers discovered that plasmids can linger in the nose of lab workers for weeks, interfering with clinical diagnostic tests. The study highlights the importance of considering occupational exposure in diagnosis and treatment.
The USC COMPASS program aims to recruit and support students from historically underrepresented backgrounds to pursue careers in regenerative medicine. Scholars will receive a minor in Stem Cell Biology and Regenerative Medicine, as well as paid summer internships and mentorship opportunities.
A Cornell research team synthesized 16 types of rock surfaces that may form on exoplanets, providing a tool to decipher their composition. The study's findings offer clues to early planetary evolution and the chemical makeup of distant planets.
Researchers developed an electronic laboratory notebook that uses knowledge graphs to describe material properties and experimental processes. The platform enables automated analysis, lossless sharing, and discovery of new materials with potential applications in energy-related devices.
A new study finds that lab adaptation involves mutations to highly conserved proteins, but natural adaptation exhibits more complex patterns, including non-conservation within functional domains. Lab conditions differ significantly from natural environments with variable and changing selective pressures.
Researchers from Johns Hopkins Medicine and Dana Farber Cancer Institute found that irisin reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice. Irisin also speeds up the transport and degradation of alpha synuclein via fluid-filled sacs called lysosomes in brain cells.
Researchers have identified two effective antibodies that neutralize all known strains of COVID-19, including Delta and Omicron variants. These breakthrough antibodies could eliminate the need for repeated booster vaccinations and strengthen immune systems, especially in at-risk populations.
Coronavirus levels in wastewater accurately predicted hospitalization peaks and healthcare pressure, enabling timely forecasting. The study's results demonstrate the value of virus surveillance in monitoring ongoing outbreaks.
A Tel Aviv University study challenges the widely-held assumption that COVID-19 originated from bats, instead highlighting their highly effective immune system. The researchers found that many reported findings on bat-borne viruses are based on antibody presence or PCR tests rather than actual virus isolation.
The Association for Molecular Pathology has published consensus recommendations for clinical TPMT and NUDT15 genotyping assays, promoting standardization across laboratories. The report identifies a minimum set of alleles to include in clinical tests, enabling healthcare professionals to provide high-quality patient care.
Research in rats found that an enriched environment leads to better maternal behavior and higher-quality breastmilk. Mothers in enriching environments had more efficient parenting, resulting in larger offspring with increased body weights and improved social behavior.
Researchers have created and observed novel vortices in an ultracold gas, exhibiting unexpected properties due to hidden discrete symmetries. The discovery may lead to breakthroughs in quantum computing and information processing.
A study published in the American Journal of Roentgenology found that combining deep-learning reconstruction with a subtraction technique yielded optimal diagnostic performance for detecting in-stent restenosis by coronary CT angiography. This approach reduced radiation exposure while maintaining high image quality.
Researchers developed a small molecule that effectively controls tumor growth by inhibiting PD-1/PD-L1 binding, overcoming accessibility and cost issues of existing antibody treatments. The new molecule has advantages in terms of affordability and oral administration, making immunotherapy more accessible to all cancer patients.
CoVaRR-Net is investing $6.9 million in 15 research projects focused on understanding Omicron subvariants and finding solutions to curb their spread. The studies will explore various aspects of variants, including viral transmission between animals and people, new variant mutations, and the impact of social factors on Indigenous Peoples.
A recent study from University of East Anglia compared 13 face shield styles in laboratory settings and surveyed over 600 people in Nigeria and Brazil about their views on face shields as PPE. The results showed that all face shields provided some protection, but none gave high levels against external droplets.
A study by Goethe University Frankfurt found that antibodies against Omicron variants BA.1 and BA.2 decline rapidly, even after a second vaccination or booster shot, offering limited protection against infection.
A Tel Aviv University study reveals that corals' fluorescence serves as a lure for plankton, which are then consumed by predators like corals. The researchers found that green-fluorescent corals were 25% more preyed upon than yellow-fluorescent ones.
Researchers at UBC Okanagan have created wearable human motion devices that can track a multitude of activities, including breathing and muscle contractions. The devices use a two-dimensional inorganic nanomaterial called MXene alongside a conductive polymer for electromagnetic interference shielding.
A new processing technique could make potatoes healthier by slowing starch digestion and reducing blood sugar spikes. The approach blocks certain digestive enzymes from reaching potato starch as quickly, leading to a more controlled release of dietary glucose.
Researchers from the University of Illinois at Urbana-Champaign created a remote laboratory activity to teach undergraduate students about enzyme kinetics. The at-home kit included basic equipment and protocols that allowed students to conduct experiments and collect data, providing an alternative to traditional lab techniques.
A new platform mimics live cellular environment to guide stem cell differentiation outside the body. Researchers from Chung-Ang University developed a novel platform based on metal-organic frameworks, which offers advantages over conventional methods for in vitro stem cell differentiation.
CHOP researchers developed CancerVar, an artificial intelligence-empowered platform for interpreting somatic cancer mutations. The tool provides standardized procedures for assessing the clinical impacts of over 13 million somatic cancer mutations.
The new COBRE grant will help WVU recruit researchers and clinician-scientists to develop innovative solutions for preventing and treating incurable vision problems. The project aims to reduce visual disparities in West Virginia by understanding the complex combination of factors that contribute to these problems.
Researchers have designed simpler magnets for twisty stellarator facilities, which could aid the development of a stellarator power plant. The new magnets have straighter sections than before while preserving their strength and accuracy.
The Lustgarten Foundation has awarded a $5 million grant to Break Through Cancer to target KRAS in pancreatic cancer. The Conquering KRAS in Pancreatic Cancer Team will integrate clinical and laboratory approaches to understand why patients respond to new therapies.
Tel Aviv University researchers develop innovative model that explains wave formation, tested in complex experiments. The model takes into account all unstable harmonics and limitations of previous models, providing high reliability for describing physical situation.
A new strain of algae has been identified that can produce green hydrogen gas via photosynthesis on an industrial scale. This breakthrough could accelerate the transition to environmentally friendly green hydrogen and reduce pollution. The researchers also plan to develop methods to increase production rates and reduce costs.
Three Brookhaven scientists, Simerjeet Gill, James Dunlop, and Sanjaya Senanayake, were selected as Oppenheimer Science and Energy Leadership Program fellows. They engage in virtual visits to other national labs, distilling their experiences into think-pieces on organizational, policy, and scientific challenges.
A new study introduces a commercially available test that enables laboratories with real-time PCR capabilities to detect known SARS-CoV-2 variants. The assay is faster and more cost-effective than traditional sequencing methods, allowing for more widespread tracking of circulating variants.
A new study identifies the age-dependent formation of TMEM106B amyloid filaments in human brains, which may not be linked to neurodegenerative diseases. Researchers found these protein structures in older but not younger individuals, suggesting a potential role in aging and other pathologies.
The ACMG Foundation presented four Next Generation Fellowship Awards to outstanding individuals in medical genetics and genomics. Ibrahim Elsharkawi and Jessica Priestley received the awards for their dedication to biochemical genetics, with support from Bionano Genomics, Spark Therapeutics, Takeda, Sanofi-Genzyme, and Pfizer.
Researchers have developed miniaturized reflectors that enlarge the uses of remote infrared spectroscopy, allowing for field-ready devices with minimal size, weight, and power requirements. The devices utilize Ge-BaF2 thin films for surface micromachined mid-wave and long-wave infrared reflectors.
Scientists developed a powerful new tool called Giraffe to improve genomic research by leveraging global genetic diversity. The tool allows for the use of a diverse pangenome reference point, enabling faster and more sensitive comparisons of short-read human genome sequences.
Researchers at Politecnico di Milano have discovered a new type of phase transition in a quasi-crystal made of laser light, allowing for the simultaneous control and modification of its properties. This breakthrough could lead to the development of novel materials with unprecedented flexibility and controllability.
Researchers at the University of Copenhagen have made a groundbreaking discovery that could phase out medications derived from pig intestines. The team has successfully created a synthetic alternative to heparin in a laboratory setting, using cell factories, similar to insulin production.
Researchers developed a novel electroanalytical technique that co-detects dopamine and uric acid in urine samples, overcoming interference from ascorbic acid. The technique uses a gold-containing ternary nanocomposite electrode, enabling simultaneous detection of low-level DA and UA under physiological conditions.
A cloud-based repository called CellRepo has been launched to track and organize digital data from engineered microorganisms. The database uses cell barcodes to monitor and track organisms, enabling faster tracing of lab origins and design details.
A new research paper by the Women In Supramolecular Chemistry (WISC) network reveals the lived experiences of supramolecular chemists during Covid-19, focusing on the impact of caring responsibilities and emotional load. The study found that mental health was significantly negatively affected among those with caring responsibilities.
Researchers discovered increased activity in the hippocampus during anesthesia and sleep, preceding Alzheimer's symptoms by years. This abnormality may enable early diagnosis and treatment of the disease.
Researchers found that smart windows with dynamic tinting can completely disinfect surfaces within 24 hours, reducing bacterial growth rates and viability. In contrast, traditional windows with blinds blocked almost all daylight, promoting contamination on glass, plastic, and fabric surfaces.
A team of scientists at the University of Missouri used small wearable sensors to gather data on how people with a traumatic hand amputation use a prosthesis versus a transplanted hand. The study found that hand transplant recipients exhibit a more balanced pattern of limb use, while prosthesis users rely heavily on their prosthetic hand.