A new study identifies the age-dependent formation of TMEM106B amyloid filaments in human brains, which may not be linked to neurodegenerative diseases. Researchers found these protein structures in older but not younger individuals, suggesting a potential role in aging and other pathologies.
The ACMG Foundation presented four Next Generation Fellowship Awards to outstanding individuals in medical genetics and genomics. Ibrahim Elsharkawi and Jessica Priestley received the awards for their dedication to biochemical genetics, with support from Bionano Genomics, Spark Therapeutics, Takeda, Sanofi-Genzyme, and Pfizer.
Researchers have developed miniaturized reflectors that enlarge the uses of remote infrared spectroscopy, allowing for field-ready devices with minimal size, weight, and power requirements. The devices utilize Ge-BaF2 thin films for surface micromachined mid-wave and long-wave infrared reflectors.
Scientists developed a powerful new tool called Giraffe to improve genomic research by leveraging global genetic diversity. The tool allows for the use of a diverse pangenome reference point, enabling faster and more sensitive comparisons of short-read human genome sequences.
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers at Politecnico di Milano have discovered a new type of phase transition in a quasi-crystal made of laser light, allowing for the simultaneous control and modification of its properties. This breakthrough could lead to the development of novel materials with unprecedented flexibility and controllability.
Researchers at the University of Copenhagen have made a groundbreaking discovery that could phase out medications derived from pig intestines. The team has successfully created a synthetic alternative to heparin in a laboratory setting, using cell factories, similar to insulin production.
Researchers developed a novel electroanalytical technique that co-detects dopamine and uric acid in urine samples, overcoming interference from ascorbic acid. The technique uses a gold-containing ternary nanocomposite electrode, enabling simultaneous detection of low-level DA and UA under physiological conditions.
A cloud-based repository called CellRepo has been launched to track and organize digital data from engineered microorganisms. The database uses cell barcodes to monitor and track organisms, enabling faster tracing of lab origins and design details.
A new research paper by the Women In Supramolecular Chemistry (WISC) network reveals the lived experiences of supramolecular chemists during Covid-19, focusing on the impact of caring responsibilities and emotional load. The study found that mental health was significantly negatively affected among those with caring responsibilities.
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers discovered increased activity in the hippocampus during anesthesia and sleep, preceding Alzheimer's symptoms by years. This abnormality may enable early diagnosis and treatment of the disease.
Researchers found that smart windows with dynamic tinting can completely disinfect surfaces within 24 hours, reducing bacterial growth rates and viability. In contrast, traditional windows with blinds blocked almost all daylight, promoting contamination on glass, plastic, and fabric surfaces.
A team of scientists at the University of Missouri used small wearable sensors to gather data on how people with a traumatic hand amputation use a prosthesis versus a transplanted hand. The study found that hand transplant recipients exhibit a more balanced pattern of limb use, while prosthesis users rely heavily on their prosthetic hand.
A booster dose of mRNA COVID-19 vaccine is required to provide immunity against the Omicron variant of SARS-CoV-2, according to a study. The traditional dosing regimens of COVID-19 vaccines available in the US do not produce antibodies capable of recognizing and neutralizing the Omicron variant.
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers developed an injectable, adhesive surgical gel that prevents postoperative adhesions and improves wound healing. The gel, dubbed HAD, was tested in rats and rabbits with promising results, showing a significant reduction in inflammation and mortality rates.
Paderborn University to establish a three-node quantum network in real urban environment, utilizing standardized equipment and protocols. The initiative aims to enhance efficiency and stability of quantum communication systems.
Researchers at Tel Aviv University successfully treated autism in animal models with medical cannabis oil, improving behavioral and biochemical parameters. The treatment showed significant improvement in compulsive and anxious behaviors, and a decrease in the concentration of the arousing neurotransmitter glutamate.
The CDC found flaws in the assay design and contamination of one component, leading to false positive reactivity in negative controls. A redesign and improved quality control measures have since been implemented.
Temperature fluctuations in labs affect over 90% of individual tests and 51 assays, including kidney function and lipid panels. Laboratories can statistically adjust for ambient temperature to reduce weather-related variability.
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Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Researchers developed an AI program that accurately identified patients at risk of serious illness due to blood infections, with an accuracy rate of 82%. The technology has the potential to serve as an early warning system for doctors, enabling them to rank patients based on their risk level.
A new study reveals that mother bats teach their pups to navigate by carrying and dropping them off at specific trees, allowing the pup to learn through repetition. The study found that pups gradually expand their navigation circles, learning to fly independently and finding food sources on their own.
Researchers have discovered that ulvan extracted from marine algae can prevent the infection of cells with the Corona virus. The study suggests that this cheap and accessible natural material may help solve the global spread of the pandemic in developing countries without access to vaccines.
A new study by the University of Houston researcher found that gender stereotypes in computer science and engineering begin at age six, leading to a lack of representation of girls and women in these fields. The study suggests that introducing high-quality STEM activities in elementary school can help close the gender gap.
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A new protocol has been developed to identify potential false-positive COVID-19 results, particularly in asymptomatic non-exposed individuals. The method involved retesting all positive results from such patients, revealing 20 out of 288 initial positives to be false positives.
Researchers developed a technology that accurately detects lies by analyzing facial muscle contractions, achieving a success rate of 73%. The study identified two distinct groups of 'liars' based on cheek muscle and eyebrow activation, with potential implications for real-life deception detection.
Scientists at the University of Southampton have created nanoparticles that can target and kill deadly bacteria hiding in human cells. The breakthrough could lead to a new treatment method using injectable or inhalation-based antibiotic-laden capsules, potentially saving thousands of lives annually.
Researchers at Tel Aviv University conducted a cross-adoption experiment with fruit bat pups to determine whether boldness is genetic or learned. The findings indicate that the pups behave like their adoptive mothers, not biological mothers, suggesting that boldness is an acquired trait passed on through mother's milk.
Scientists have discovered that hypervelocity dust impacts on a spacecraft can produce plasma explosions and create debris clouds, disturbing its operations. These events can also generate clouds of debris that expand away from the spacecraft.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers have made significant breakthroughs in understanding Parkinson's disease, revealing that affected neurons don't die but lose properties. This knowledge opens the door to new therapeutic treatments targeting the cell body, rather than just axons.
Researchers developed a tool to investigate cause of death when skeletonised remains are recovered, providing a breakthrough in forensic lightning pathology. The study identified unique markers of lightning damage deep within the human skeleton, allowing for recognition of lightning strikes even when only dry bone survives.
Researchers created a laboratory to simulate comets in space-like conditions, measuring their properties and evolution. The CoPhyLab chamber allows scientists to compare samples and track gas evaporation and particle loss, providing insights into comet formation and solar system history.
A team of UBCO researchers developed a recipe for a clean-burning, power-boosting aircraft fuel by adding graphene oxide nanomaterials to ethanol. This mixture improves the burn rate by about eight per cent, reducing carbon footprint and increasing engine power.
The Association for Molecular Pathology (AMP) has published new guidelines to improve the US' ability to respond to emerging infectious disease outbreaks. The recommendations focus on better collaboration between public health, clinical laboratories, and government agencies.
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
The cost of establishing laboratories to track antimicrobial resistance in Southeast Asian hospitals is substantial, making it challenging for many countries to implement such programs. Financial support is crucial to overcome these costs and provide effective antimicrobial resistance monitoring.
A new study has identified unique genetic codes in the placenta that could detect pregnancy complications earlier than current tests. The researchers found specific biomarkers in maternal blood that indicate placental health and fetal well-being, allowing for real-time assessment throughout pregnancy.
Researchers designed novel molecules that bound tightly to SARS-CoV-2's molecular scissors, inhibiting the virus's replication. The breakthrough could lead to new treatments for COVID-19.
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Researchers found that validating accuracy of in vitro diagnostic tests carried costs and had higher true limits of detection than reported. The study suggests mechanisms for expanded regulatory oversight by the FDA, including technology certification to assess performance of complex diagnostic tests.
The European facility will study samples from asteroids and the Moon at a macroscopic level, unlocking exciting science on the formation and evolution of planetary bodies. The first instruments will be delivered in summer 2022, with the laboratory expected to fully operational by 2023.
Researchers have identified the potential of 7HP349 as an oral medication to strengthen the effectiveness of vaccines, particularly for populations that struggle with immunosuppression. The study suggests adding 7HP349 to standard vaccination can improve vaccine efficacy without reformulating the vaccine.
Researchers at West Virginia University are monitoring wastewater statewide for COVID-19 using an egg-shaped robot that collects samples every 20 minutes. The project aims to develop a testing network throughout the state, providing early indicators of changes in community-level spread of COVID-19.
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
The Daylight Award 2022 is now open for nominations, honoring groundbreaking research on the effects of daylight on human health and well-being. The award also recognizes innovative architectural projects showcasing unique uses of daylight, aiming to improve living conditions and environmental impact.
Referral guidelines for nephrology care are shifting towards identifying patients at higher risk of kidney failure. A study using Veterans Health Administration data found that referring patients with a two-year risk of kidney failure above 1% would identify those at highest median risk.
A University of Missouri researcher is using a grant from the National Science Foundation to explore how time can factor in a building collapse. She's conducting thousands of hours of laboratory tests to determine the breaking points of reinforced concrete building materials.
A team from Beth Israel Deaconess Medical Center created all-new swabs for COVID-19 testing in just three weeks by leveraging open-source collaboration and 3D printing. The swab crisis highlighted the importance of cooperation, openness, and scalability in solving complex problems.
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers from the University of Birmingham have confirmed a novel COVID-19 testing method called RTF-EXPAR that is highly sensitive and fast, giving results in under 10 minutes even at low viral levels. The test was shown to be equivalent to PCR and LAMP tests but faster.
A recent study found SARS-CoV-2 infection among maternal-infant pairs to be extremely rare in early infancy. The findings suggest that while transmission is uncommon, continued monitoring and vaccination efforts are necessary to protect newborns from COVID-19 and its variants.
A team of Beckman researchers developed software to boost infrared imaging-based cancer diagnosis, enhancing image resolution and accelerating recording speeds. The software integrates data analysis and reduces limitations associated with IR imaging, making it faster and more accurate.
A study from the University of South Carolina's Environmental Health & Disease Laboratory found that andrographolide successfully restored bacteriomes and viromes, increasing beneficial bacteria and decreasing harmful bacteria. The treatment also decreased gut inflammation and neuroinflammation in veterans with Gulf War Illness.
A synthetic hinge concept developed by Indiana University School of Medicine Professor Michael A. Weiss and his team could lead to a breakthrough in 'smart' insulin therapy. The invention exploits a natural mechanism that allows the insulin to adjust its activity based on blood glucose levels, which could transform diabetes care.
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
The American College of Medical Genetics and Genomics (ACMG) has partnered with Elsevier to publish its official journal, Genetics in Medicine. The partnership aims to increase the journal's visibility and influence in medical genetics and genomics research.
The project aims to identify potential environmental costs of deep-sea activities to inform responsible use. It will connect diverse science and policy experts in industry, academia, and private institutes to guide sustainable practices.
Scientists investigate e-cigarette formation of formaldehyde, a human carcinogen, under various use patterns and devices. The study aims to identify key parameters underlying harmful substance production, informing public health and policy.
The Virginia Tech Molecular Diagnostics Laboratory developed a novel test for COVID-19, targeting three regions of the gene for increased accuracy. The lab has processed over 130,000 tests since April 2020, expanding public health lab testing capacity in Southwest Virginia.
Researchers at the U.S. Army's Institute for Soldier Nanotechnologies identified a new material that absorbs impact more efficiently than steel, Kevlar, aluminum and other materials of comparable weight. The nanoarchitected material features impressive properties like exceptional lightness and resilience.
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers use ultrafast electron diffraction to observe an electronic device as it operates, discovering a new intermediate state that enables fast and energy-efficient switching. The study paves the way for next-generation electronic devices that can meet the world's growing needs for data-intensive computing.
Researchers developed an optimized schedule for automated biology lab robots, maximizing experiments within time and resource constraints. The S-LAB framework accounts for time constraints and resource conflicts, improving efficiencies in life science experiments.
Researchers have discovered that rat whiskers act like antennae to amplify tiny stick-slip motions caused by friction, enabling the brain to perceive surface textures. This breakthrough has far-reaching benefits for design of textured surfaces for visually impaired and robotic safety in low light environments.
A laboratory study reveals that haze particles produced under different conditions have varying properties, determining the clarity of an exoplanet's atmosphere. Haze removal depends on surface energy, with particles having high surface energy being easily removed and resulting in clear skies.
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Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
Researchers at Radboud University have identified new biomarkers for pyridoxine-dependent epilepsy, enabling better and earlier treatment of the disease. The discovery could lead to optimized treatment and improved chances of preventing cognitive disability.
A new international study found that laboratory-developed protein spikes consistent with COVID-19 virus are highly similar, providing reassurance for vaccine design and antibody testing. The study used glycan coatings to mimic the infectious virus and showed consistent results across five laboratories worldwide.
The UOC's RLAB-UOC enables students to conduct practical experiments with real electronic and communications equipment remotely. The study found that students rate the laboratory and working with real tools positively, improving their learning experience and acquiring practical skills.