Articles tagged with Dementia
Research published in British Journal of Ophthalmology found that normal-tension glaucoma is associated with an increased risk of cognitive impairment and possibly dementia. The study suggests that the disease pathways for normal-tension glaucoma may be similar to those for dementia.
Researchers at Flinders University in Australia have found a link between normal-tension glaucoma and cognitive impairment, with patients having this type of glaucoma being more than twice as likely to develop dementia. The study suggests that normal-tension glaucoma may share similar neurodegenerative pathways with dementia.
Researchers have discovered 12 genetic regions linked to lacunar strokes, which can lead to long-term disability and dementia. The study provides new hope for preventing and treating this devastating type of stroke.
Persistent midlife loneliness is linked to a higher risk of developing dementia and Alzheimer's disease, while transient loneliness may actually reduce the risk. Researchers found that recovering from loneliness after 18 years may also lead to lower risk of dementia onset.
Research suggests non-drug therapies like exercise and social interactions may reduce symptoms of depression in people with dementia. These interventions are found to be as or more effective than drugs in treating depression, suggesting a shift towards 'social' prescribing.
Researchers evaluated the association between a recent dementia diagnosis and suicide attempt among older adults. The study found that individuals with dementia were at a higher risk of attempting suicide compared to those without the condition.
A large proportion of dementia deaths in England and Wales may be due to socioeconomic deprivation, according to new research. The team found that socioeconomic deprivation was associated with younger age at death and poorer access to accurate diagnosis.
A study of 500,000 participants found that eating 25g of processed meat daily was associated with a 44% increased risk of developing dementia. In contrast, consuming 50g of unprocessed red meat daily was linked to a 19% lower risk of the disease.
Primary care professionals can identify and monitor risk factors early to prevent cognitive decline. The American Heart Association recommends addressing 13 key factors to optimize brain health, including Life's Simple 7 lifestyle targets.
Researchers at Case Western Reserve University have determined the structure of protein fibrils linked to Lou Gehrig's disease and other neurodegenerative disorders. The findings provide clues on how toxic proteins clump and spread between nerve cells in the brain, potentially leading to the development of new treatments.
Researchers found a strong association between ischemic stroke occurrence and severity with an increased risk of dementia. The study's findings emphasize the importance of preventing stroke to maintain high levels of physical and cognitive function and quality of life.
Research suggests that people with severe retinopathy are more likely to have a diseased-looking brain on MRI. The study found an association between retinopathy and increased risk of stroke, dementia, and mortality in adults.
A recent study published in Annals of Clinical and Translational Neurology found that head injuries in people under 50 can lead to lower cognitive scores at age 70. The researchers discovered a small but significant impact on brain health and thinking skills, potentially accelerating the normal aging process.
A new study found that 1 in 7 people with dementia are taking at least three brain and nervous system medications, which can accelerate memory loss and increase the risk of falls, overdoses, and death. Regular prescription drug reviews could help spot risky combinations.
A new Penn Medicine research reveals that a single head injury can lead to dementia later in life, with the risk further increasing with more head injuries. Women and white participants are at higher risk of dementia after head injury compared to men and black participants.
Researchers found a significant association between estrogen receptor α PvuII polymorphisms and dementia in a Brazilian cohort. The study suggests that this polymorphism may contribute to the development of dementia, particularly in elderly populations.
Researchers from Kanazawa University developed a new computerized cognitive test that can accurately screen for mild cognitive impairment (MCI) and dementia in under 5 minutes. The test, called the C-ABC, has been shown to be effective in distinguishing normal cognition from MCI and dementia using scores from just two questions.
A recent analysis found a lack of consensus regarding palliative care referral in dementia patients, highlighting the need for standardized criteria. Specialist palliative care can optimize quality of life and provide relief from symptoms, but its application varies widely.
Researchers at UTA will match students with dementia patients for a two-year project using reminiscence therapy and digital memoirs to improve social and emotional well-being. The team hopes this intergenerational approach will promote better outcomes for older adults with Alzheimer's disease.
The report reviews recent changes in EU research policy, identifies key barriers and enablers for data sharing, and maps the Horizon 2020 dementia research portfolio. Key findings include a need to overcome technical, financial and motivational obstacles to data sharing, as well as involving people with dementia in research design.
Researchers discovered white matter hyperintensities are more common and severe in people with frontotemporal dementia compared to Alzheimer's disease and healthy controls. The study suggests these changes contribute to cognitive problems rather than vascular factors.
A genetic study of Lewy body dementia suggests that the disease is caused by a spectrum of problems seen in both Alzheimer's and Parkinson's diseases. Five genes have been identified as critical to the development of Lewy body dementia, with variations in these genes also linked to increased risk of Alzheimer's and Parkinson's diseases.
A study published in Journal of the American College of Cardiology found that mid-life cardiovascular disease prevention can protect against later dementia. The research suggests that controlling cardiovascular risk factors early on can reduce brain vulnerability to cognitive dysfunction.
A recent study published in Aging found that very short sleep duration, poor-quality sleep, and snoring were associated with a higher risk of incident dementia. The study also revealed an increased risk of all-cause mortality among participants who reported less than five hours of sleep per night.
A study found patients with dementia twice as likely to contract COVID-19 and experience worse outcomes. African Americans with dementia faced a near-threefold higher risk of infection. The researchers emphasized the need for strategies balancing safety from COVID-19 with protection from social isolation and health-related harms.
A recent 18-year study by Imperial College London reveals that cancer is now the leading cause of death among people with diabetes in England. Death rates from heart disease and stroke declined significantly during this period, but improvements were more modest for cancer-related deaths.
A research team from the University of Kansas is developing autonomous driving technology for people with cognitive impairments, aiming to increase mobility and independence. The team will refine highly automated driving systems designed for individuals with mild cognitive impairment and dementia.
Researchers at INRS have discovered two early plasma markers that can detect Alzheimer's disease five years before its onset, enabling earlier intervention. The study found that these markers are present in plasma extracellular vesicles and can be analyzed through a blood test, opening up new possibilities for studying the disease.
A new study suggests that people with enlarged fluid-filled spaces in the brain around small blood vessels are more likely to develop cognitive problems and dementia over time. Researchers found that those with severe cases were nearly three times more likely to develop dementia than those with fewer or no enlarged spaces.
Research suggests that regular afternoon napping may be associated with better mental agility, including improved locational awareness, verbal fluency, and working memory. The study found significant differences in cognitive performance scores among nap-takers compared to non-nappers.
Researchers found that people with Parkinson's disease who have visual problems are more likely to develop dementia, with underlying changes in brain wiring explaining the connection. Vision tests may provide a window of opportunity to predict Parkinson's dementia before it begins.
Researchers found that approximately half of AD cases are mild, while one-fifth are severe. Early intervention in the mild stage is crucial to slow decline and prevent progression.
A new study found that people in rural areas are less likely to receive specialty care from neurologists, with those living in urban areas more likely to see a specialist for common conditions like dementia and stroke. However, telemedicine can help extend neurological services to underserved areas.
Researchers at Trinity College Dublin identify genetic mutations linked to ultra-rare condition ALSP, revealing that dysfunctional white blood cells drive brain damage and BBB breakdown. The study's findings may pave the way for targeted therapies for other forms of dementia.
A UCSF clinical psychologist has taken aim at the NFL for using race norms to deny payouts to Black players diagnosed with dementia. She advocates for a more nuanced approach that accounts for social determinants of brain health, such as language and occupation, to provide fair compensation.
The number of people with dementia from minority ethnic groups is increasing in Europe, but uptake of services remains low. Alzheimer Europe has launched a guide to support health and social care workers in providing intercultural dementia care.
A Finnish study of 1,449 participants found that those with better midlife heart health scores had a lower risk of dementia later in life. Maintaining lifelong cardiovascular health behaviors may reduce dementia risk, according to the findings.
Researchers found that apathy can signal cognitive decline in people with frontotemporal dementia, even decades before other symptoms appear. The study used brain scans and memory tests to track changes in apathy over time and found that it predicted cognitive problems in individuals with a genetic mutation.
Researchers from KAIST and Florida State University developed a model describing PER molecule motion in cells, showing how aging and diseases disrupt circadian rhythms by hindering condensation around the cell nucleus. This leads to irregular sleep-wake cycles and unstable rhythms.
Alzheimer Europe's new report highlights the need to prioritize dementia research and policy in the EU. The organization recommends allocating fair resources to existing programs, prioritizing dementia within chronic diseases policies, and recognizing it as a disability.
Researchers found that higher baseline NT1 levels in blood samples predicted the risk of cognitive decline and Alzheimer's disease dementia. The study used a cohort of cognitively normal older adults and showed that NT1 levels could be measured before enrollment in AD prevention trials.
A $2.5 million project aims to develop a virtual assistant tool for dementia carers in Australia, New Zealand, Indonesia, and Vietnam. The tool will provide video instructions and translate into different languages, improving mental health and wellbeing for over two million carers.
Researchers have discovered a genetic connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), with the same huntingtin mutation associated with Huntington's disease. The study opens up possibilities for gene therapy targeting this mutation, which could lead to personalized medicine.
Researchers have discovered a potential window to the brain in Sanfilippo syndrome, a rare and untreatable form of childhood-onset dementia. The study uses retinal imaging techniques to monitor disease progression and therapeutic efficacy, providing new hope for patients.
The Alzheimer's Association, Global Brain Health Institute, and Alzheimer's Society have partnered to fund 23 small-scale pilot projects addressing global challenges in dementia. These projects focus on innovative approaches to awareness, diagnosis, treatment, and care for individuals with Alzheimer's disease and other dementias.
A nationwide analysis of dementia incidence from 2000 to 2016 reveals significant racial disparities in the US, with Black and Hispanic populations more likely to develop dementia than White Americans. The study suggests that targeted interventions are needed to address these disparities.
A new study by Johns Hopkins Bloomberg School of Public Health and Federal Reserve Board of Governors found that individuals with dementia miss payments on bills as early as six years before diagnosis. Financial symptoms like missed payments and subprime credit scores are unique to dementia and can be used as early predictors.
A new study found that air pollution in neighborhoods is associated with an increased likelihood of amyloid plaques, a hallmark of Alzheimer's disease. The study suggests that exposure to microscopic airborne particles may be implicated in tens of thousands of cases of the disease.
Researchers analyzed Medicare data to characterize financial presentation of Alzheimer's and related dementias before diagnosis. They found a significant association between the two, suggesting financial errors may be an early indicator of dementia.
A study published at the University of Exeter Medical School has discovered specialized nerve cells called speed-sensitive cells in the brain's entorhinal cortex that malfunction in Alzheimer's disease. This malfunction disrupts the brain's map, leading to spatial navigation difficulties.
A study led by The Jackson Laboratory and University of Maine found that the expression of Dlgap2 is associated with memory loss in mice and risk for Alzheimer's dementia in humans. Dlgap2 influences the formation of dendritic spines on neurons, which can affect cognitive function.
A new study reveals that Z-drugs are associated with adverse effects similar to benzodiazepines, particularly for people with dementia taking higher doses. The research recommends avoiding higher dose Z-drugs and instead considering non-pharmacological alternatives.
A new study found that only a quarter of Medicare beneficiaries receive structured cognitive assessments during annual wellness visits. The researchers suggest that variations in wellness visits and cognitive assessments between Medicare coverage types are not well understood, and more research is needed to validate the differences.
A recent study found that individualized brain stimulation therapy improves language performance in stroke survivors with aphasia, targeting abnormal activity outside the damaged tissue. The therapy also shows promise for individuals with dementia, highlighting a personalized approach to treating this debilitating disorder.
A new study found that patients with rheumatoid arthritis taking biologic DMARDs have a 17% lower risk of developing dementia compared to those on conventional synthetic DMARDs. The treatment reduces inflammation, which may explain the decreased risk.
A new study analyzing cognitive decline in diverse Latinx populations found that the APOE-ε4 gene variant is associated with increased risk of cognitive decline. Interestingly, a higher proportion of genetic Amerindian ancestry was found to protect against this risk.
A three-year study published in 'Alzheimer's & Dementia' shows that a multinutrient formulation can significantly slow the deterioration of cognitive performance and brain atrophy in early Alzheimer's patients. Patients who received the nutrient drink suffered between 40-70% less cognitive impairment than those in the control group.
A new study from University of East Anglia found that people with dementia are at higher risk of going missing in areas with dense and disordered road networks. The research identified environmental risk factors that contribute to the issue, including complex intersections and disorganized layout.
The inaugural awards promote translational opportunities and therapeutics development at Harvard and affiliated hospitals. Five research projects targeting diverse conditions, including type 1 diabetes and severe asthma, will each receive $1 million over two years to advance their efforts.
Researchers develop a new PET-based imaging technique to detect abnormal tau protein deposits in the brain, which can diagnose Alzheimer's disease and frontotemporal lobar degeneration disorders with high accuracy. The method has shown promising results in detecting tau aggregates in patients with various forms of dementia.