Articles tagged with Memory Disorders
A randomized controlled trial shows that a behavioral treatment, Behavioral Activation, can reduce the risk of future memory loss by increasing social, cognitive, and/or physical activity. The study found an 88% reduction in cognitive decline compared to the control group.
A novel mechanism links epigenetic changes to translational control in the brain, controlling downstream regulation of translation during fear memory reconsolidation. This finding may help attenuate maladaptive memories in psychiatric disorders.
Researchers found that ACE inhibitors can block the activation of brain cells called microglia, which contribute to memory loss and cognitive impairments in SLE patients. The study suggests that these drugs may be used to preserve the memory of lupus patients.
A new study published in Scientific Reports suggests that severe trauma from war, torture, and natural disasters may not necessarily lead to posttraumatic stress disorder (PTSD) in refugees. However, those who struggle to control their memories are more likely to exhibit symptoms of PTSD.
A study from the University of Arizona found that individuals with the APOE e4 gene variant who carry it described memories with less vivid detail than those without it. The researchers hope to develop a clinical test sensitive enough to detect preclinical brain changes of Alzheimer's disease.
A Northwestern University study found that noninvasive brain stimulation improved the brain's ability to form new memories, with increased excitability lasting at least 24 hours. The research has implications for treating memory problems due to aging or brain damage.
A Baylor University study finds that children with certain types of brain tumors who undergo radiation treatment are more likely to forget recent memories than pre-treatment ones. The study suggests that radiation impacts the development of new cells in the hippocampus, leading to deficits in forming new memories.
A recent study published in the Journal of Neurochemistry reveals that long-term use of cannabis or cannabis-based drugs impairs memory in mice, with significant effects on brain function and communication between learning and memory regions. The research highlights the potential negative side effects of long-term cannabinoid exposure.
Researchers found that 'acting out' scenarios can improve prospective memory, a skill that reminds people to take action in the future. The study suggests that this technique may support individuals with mild cognitive impairment, leading to safer, more independent living.
Researchers at the University of Toronto have identified a mechanism that recreates vivid sensory experiences from memory using smell. The findings shed light on how sensory-rich memories are created and stored in our brains, and could explain why loss of smell is recognized as an early symptom of Alzheimer's disease.
Researchers at Lancaster and Lisbon Universities found that long-term exposure to cannabis impairs learning and memory in animals. Brain imaging studies showed the drug affects key brain regions involved in learning and memory.
Researchers found that physical activity increases hippocampal capacity by promoting neurogenesis, which clears out old memories. This process helps maintain memory capacity throughout life, particularly for those with Alzheimer's disease.
Researchers have discovered a specific brain neuron with a central role in learning and improving memory formation. The study found that activating this brain cell improved memory function, while overactivating it led to impaired learning and memory.
Researchers identified a new mechanism involved in age-related memory loss, where specific changes in brain circuit signaling lead to abnormal neuron responses. The study found that an adenosine receptor, A2A, is concentrated in neurons and its overactivation leads to increased glutamate release.
Researchers found that overproduction of ephrin-B1 in astrocytes weakens memory retention in mice. In contrast, decreased ephrin-B1 levels lead to more synapses and better learning. The study suggests that glial cells play a crucial role in regulating learning and memory.
A study by psychologists at the University of Illinois found that focusing on contextual details of emotional memories can improve cognitive performance and reduce negative effects. By shifting focus away from emotion and toward context, individuals can redirect brain resources to tasks and process memories more deeply.
A computational model suggests that older memories are affected in depression, with longer episodes causing more extensive memory deficits. The study's findings imply that major depressive disorder could have far-reaching consequences, including the loss of remote memories that do not recover even after the depression subsides.
A study by Joslin Diabetes Center researchers has found a correlation between long-term type 1 diabetes and mild cognitive decline, particularly in memory. The decline is also associated with an increased risk of cardiovascular disease.
Researchers discovered that a gene associated with human intellectual ability is necessary for normal memory formation in mice. Mice with the gene deletion replay shorter fragments of their previous experiences during periods of rest, impairing their ability to consolidate memories.
Researchers at Ohio State University found that mice housed in groups had better memories and healthier brains than those living in pairs. The study suggests that social connections can positively influence the aging brain and may be a key to preserving cognitive health.
Researchers identified a genetic link between SuperAgers and better memory retention, suggesting that therapies targeting the MAP2K3 gene could reduce age-related memory decline and Alzheimer's disease risk.
Researchers found that sleep spindles, brief bursts of brain activity, are linked to memory reactivation and improve retention. The rhythmic pattern of spindles may help segregate memories, preventing interference between them.
A recent study published in Springer's Archives of Sexual Behavior suggests that older adults who engage in regular intimate activities and emotional closeness do not experience a slower rate of cognitive decline compared to those who are less active. However, this relationship is only observed on short-term memory tests, not over time.
Researchers at Indiana University found that rats can replay past events from memory using episodic memory replay. The study confirms the ability of animals to recall specific events and their order, which is essential for making sense of scenarios. This breakthrough could lead to more effective treatments for Alzheimer's disease.
Researchers found that trace amounts of beta-amyloid predicted future levels of tau and both preceded memory decline. Early intervention is crucial in slowing Alzheimer's disease progression by targeting anti-amyloid therapies before symptoms appear.
Researchers found that as working memory load increases, brain wave synchrony among three key regions breaks down, leading to a loss of communication and sustaining working memory. This study sheds light on the intrinsic limit of conscious thought and cognitive performance, potentially explaining psychiatric disorders.
Caffeine found to exacerbate neuropsychiatric symptoms in Alzheimer's disease, impacting anxiety and cognitive flexibility. Long-term consumption worsened BPSD-like symptoms in mouse models.
Researchers successfully implemented a prosthetic system that utilizes individual brain cell patterns to enhance memory encoding and recall. In a pilot study, participants showed significant improvements in episodic memory performance, with the most notable gain observed when stimulated with correct-answer codes.
A study published by the American Academy of Neurology found that estradiol therapy via skin patches maintained brain volume and reduced amyloid plaque deposits in women. Meanwhile, estrogen pills caused greater structural changes in the brain, which stopped once treatment was stopped.
A study by Massachusetts General Hospital researchers identified a neural circuit mechanism involved in preserving memory specificity and a genetic 'switch' that can slow down memory generalization. Targeting levels of abLIM3 protein could improve memory in aging and reduce symptoms of PTSD.
Researchers used high-resolution functional brain imaging to study memory performance in younger and older adults. The study found that object memory is more vulnerable to age-related decline than spatial memory, with a specific region of the brain linked to this deficit.
A study by University of California, Irvine researchers found that high-resolution brain imaging can identify the underlying causes of differences in memory proficiency between older and younger adults. The study revealed that object memory is more vulnerable to age-related decline than spatial memory.
Researchers discovered that older adults naturally tap into this strategy to bolster memory when remembering becomes difficult. They unknowingly move their eyes in the same pattern over and over again, even when looking at a blank screen.
A preliminary study has found an association between central hearing loss and mild cognitive impairment in some people. Researchers discovered that individuals with central hearing loss were twice as likely to have mild cognitive impairment compared to those without hearing loss.
A study of 312 participants who had surgery and 652 participants who did not found that surgery was associated with a decline in immediate memory by one point out of 30 possible test scores. Additionally, reduced working memory decline was linked to longer cumulative operations.
Researchers used fMRI to study brain activity while watching Memento, finding repeating patterns in the brain that correspond to key scenes. These 'neural fingerprints' help viewers piece together the storyline, revealing insights into how the brain processes narratives and memory.
Researchers at George Washington University are exploring a possible link between post-traumatic stress disorder (PTSD) and cardiovascular disease. A recent grant of over $1.5 million will investigate the brain renin-angiotensin system's role in this connection.
Researchers have discovered that removing a molecular brake pad called histone deacetylase 3 (HDAC3) restores flexibility and allows the brain to form long-term memories normally. This breakthrough could potentially lead to new treatments for improving memory formation in older individuals.
A study led by Duke Health found that a short course of the Alzheimer's drug donepezil can reverse structural and genetic brain changes caused by alcohol exposure in rats. This reverses dendritic spine density, affecting learning and memory. The research identifies a specific gene target for potential repair.
A new study published in Neurology suggests that individuals who do not recognize their own memory problems are nearly threefold more likely to develop dementia within two years. This lack of awareness is associated with impaired brain metabolic function and higher rates of amyloid deposition, a protein linked to Alzheimer's disease.
A team of University of Pennsylvania neuroscientists developed a system to monitor brain activity and trigger stimulation responsively, improving learning and memory performance. The study found that precisely timed electrical stimulation can reliably enhance memory function in patients with memory loss.
Researchers at Ohio State University Wexner Medical Center conducted a study on a brain pacemaker to slow the decline of problem-solving and decision-making skills in patients with Alzheimer's disease. The deep brain stimulation (DBS) implant improved cognitive, behavioral, and functional abilities in patients.
Researchers at Mayo Clinic discovered that electrical stimulation of the lateral temporal cortex enhances word recall, making it easier for patients to remember previously viewed words. The study suggests potential new treatment devices for memory and cognitive deficits.
Researchers found that early personality changes can lead to noticeable behavior problems, including depression and anxiety. The study suggests that diagnosing these early changes could help develop earlier treatments for Alzheimer's disease.
A new study by UCLA researchers found that daily consumption of curcumin improved memory and mood in people with mild, age-related memory loss. The study, which involved 40 adults aged 50-90, showed significant improvements in cognitive power and reduced amyloid and tau signals in the brain.
Research by neuroscientists at New York University uncovers neural circuits that may be intact but improperly tuned, leading to inflexibility in learning new information. The study sheds light on the cognitive deficit characteristic of Fragile X syndrome, which impairs memory use in multiple ways.
Adolescents with OCD experience widespread learning and memory problems, affecting daily functioning and school performance. Researchers found impaired cognitive flexibility and goal-directed control, highlighting the need for structured environments to support their development.
Scientists at UC San Diego report that distinct, sparse sets of hippocampal neurons encode episodic memories, recollections of past events. The findings provide significant insights into the mechanisms of memory and have implications for health-related reasons, including Alzheimer's disease.
Dr. Chiaravalloti will test the modified Story Memory Technique's impact on new learning and memory abilities in older adults with mild cognitive impairment. The study aims to improve daily functioning and quality of life for this population.
A new guideline from Mayo Clinic suggests that exercise can help people with mild cognitive impairment, which is an intermediate stage between normal aging and dementia. Twice-weekly workouts of 30 minutes or less may slow down the progression of symptoms.
Researchers found that overexpressing FKBP1b restored gene expression in hippocampal neurons, improving water maze performance and reversing age-related memory impairments in rats. The study suggests addressing FKBP1b deficiency may be a new avenue for countering age-related memory loss.
Researchers found that direct electrical stimulation of the human amygdala can enhance next-day recognition of images, with a significant boost in memory performance. The study used low-level current and showed an improvement in memory recall for patients with epilepsy and average memory performance.
A study by Temple University researchers found that mice fed canola oil daily suffered impaired working memory and increased amyloid plaques, indicative of neuronal damage. The findings suggest that long-term consumption of canola oil may be detrimental to brain health.
Researchers found that six weeks of intense exercise improved high-interference memory, a type of memory that allows us to distinguish between similar objects. Participants who experienced greater fitness gains also showed increased brain-derived neurotrophic factor (BDNF), supporting the growth and function of brain cells.
Researchers found that a specific G protein linked to dopamine receptors plays a role in both forming and erasing memories. The study suggests that the brain has an 'optimization process' that whittles away unnecessary memories, allowing for better function.
A study by McMaster University neuroscientists found that even mild trauma from contact sports can disrupt the production of new neurons in the hippocampus, a region critical to memory. Temporary memory losses were observed in concussed athletes, while scores improved after a reprieve from their sport.
A study published in Nature Communications reveals that membralin plays a crucial role in regulating the cell's machinery for producing beta-amyloid, the protein responsible for neuronal death in Alzheimer's disease. The researchers found that membranes with lower levels of this protein are associated with increased neurodegeneration a...
The GuidAge study suggests that memory complaints reported by elderly individuals can predict a decline in cognitive performance. Five specific items on the McNair and Kahn Scale were found to be statistically significant, including difficulty remembering phone numbers, appointments, and instructions.
A selective PDE4D inhibitor, BPN14770, has shown promise in treating Fragile X syndrome by reducing hyperarousal and improving social interactions. The treatment also exhibited long-term benefits, with no tolerance observed.
A neuroprotective compound has been shown to protect against nerve cell death, depression, and memory problems in a rat model of Alzheimer's disease. The treatment also prevented the development of depression-like behavior and delayed cognitive decline.