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Biomembrane research findings could advance understanding of computing and human memory

Scientists discovered that an artificial cell membrane can exhibit long-term potentiation, a hallmark of biological learning and memory, persisting for many hours. This finding has the potential to revolutionize next-generation computing materials and architectures by merging functions of processing and memory in neuromorphic computers.

SourceDOE/Oak Ridge National Laboratory·JournalProceedings of the National Academy of Sciences·DateDec 7, 2022

During sleep, one brain region teaches another, converting novel data into enduring memories

Researchers used a neural network model to study how brain regions interact during sleep. They found that the hippocampus and neocortex work together to convert fleeting information into long-term memory. The findings suggest that alternating between REM and slow-wave sleep stages is crucial for strong memory formation.

SourceUniversity of Pennsylvania·JournalProceedings of the National Academy of Sciences·DateOct 24, 2022

Deep learning with light

Researchers at MIT have developed a new method that uses optics to accelerate machine-learning computations on low-power devices. By encoding model components onto light waves, data can be transmitted rapidly and computations performed quickly, leading to over a hundredfold improvement in energy efficiency.

How the smell of food can enable “time travel”

Researchers at Lancaster University found that 3D printed flavor-based cues can stimulate rich sensory accounts and strong emotional connections in older adults, recalling memories from their youth. This technology has potential applications for dementia care, allowing individuals to relive cherished moments through the power of smell.

SourceLancaster University·JournalHuman-Computer Interaction·TypeExperimental study·DateOct 5, 2022

Learning on the edge

Researchers developed a new technique that enables on-device training using less than a quarter of a megabyte of memory, reducing the need for powerful computers and central servers. This approach preserves privacy by keeping data on the device, making deep learning more accessible for low-power edge devices.

SuperAger brains contain ‘super neurons’

Researchers found significantly larger neurons in the brain's memory region of SuperAgers compared to cognitively average peers, individuals with early-stage Alzheimer's disease, and younger individuals. These larger neurons were spared from tau tangles, a hallmark of Alzheimer's disease, suggesting they may maintain structural integrity.

SourceNorthwestern University·JournalJNeurosci·TypeObservational study·DateSep 30, 2022

Talk with your hands? You might think with them too!

A study by Osaka Metropolitan University's Professor Shogo Makioka and colleagues investigates embodied cognition mechanisms in the brain. The researchers found that when participants' hands were restrained, brain activity related to semantic processing of words decreased, and verbal responses became slower. These findings support the ...

SourceOsaka Metropolitan University·JournalScientific Reports·TypeExperimental study·DateSep 15, 2022

Making a memory positive or negative

Salk researchers identify neurotensin as a key molecule in the brain's valence assignment process, which associates good or bad feelings with memories. The discovery could lead to a better understanding of why some people retain more negative emotions than positive ones, and may pave the way for new therapeutic targets.

SourceSalk Institute·JournalNature·DateJul 20, 2022

Research probes how people control unwanted thoughts

A new study published in PLOS Computational Biology suggests that proactively avoiding associations can help prevent the repetitive looping of unwanted thoughts. Researchers found that most people use reactive control, which can strengthen unwanted thoughts, but also discovered that preemptive control can partially mitigate this effect.

SourcePLOS·JournalPLOS Computational Biology·TypeExperimental study·DateJul 14, 2022

Physical consequences improve motor learning

Research published in eNeuro found that physical consequences, such as slipping, can improve motor learning by refining movement responses to mistakes. Participants who experienced a slip improved their ability to adjust steps to new situations, demonstrating better generalization of learned skills.

SourceSociety for Neuroscience·JournaleNeuro·TypeExperimental study·DateMay 23, 2022

Protein linked to intellectual disability has complex role

The study found that the fragile X protein regulates the opening and closing of the GABA-A receptor in neurons from the brain's memory center, influencing how such neurons process information. This nuanced understanding may hold the key to developing effective therapies for fragile X syndrome.

SourceWashU Medicine·JournalCell Reports·TypeExperimental study·DateMay 17, 2022

Study shows that intranasal Rx halts memory decay in experimental Alzheimer’s model

Researchers at LSU Health New Orleans and Karolinska Institutet found that intranasal application of pro-resolving lipid mediators arrested memory loss and brain degeneration in an experimental Alzheimer's model. This discovery opens up new possibilities for therapeutic interventions for Alzheimer's disease.

SourceLouisiana State University Health Sciences Center·JournalCommunications Biology·TypeExperimental study·DateMar 21, 2022

Unexpected element in aging process discovered

A new discovery by VUB professor Ann Massie's research group reveals a strategy that prolongs life expectancy and preserves hippocampal function in the aging brain. The absence of system xc- has positive effects on mouse longevity and cognitive function, challenging current understanding of the aging process.

SourceVrije Universiteit Brussel·JournalMolecular Psychiatry·DateFeb 18, 2022

Study shows high prevalence of depression, anxiety and post-traumatic stress disorder after COVID-19

A study tracking 425 patients post-COVID-19 found high prevalence of cognitive deficits, psychiatric impairments, and significant memory decline. Researchers observed no correlation between the severity of the disease or socio-economic factors with psychiatric alterations, suggesting a possible link to delayed inflammatory processes.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalGeneral Hospital Psychiatry·DateFeb 15, 2022

Stargazing in the brain: “Star-like” cells display unique activity patterns

Researchers at OIST used advanced imaging to record signaling within single astrocytes, revealing ultra-fast signals on par with neurons and patterns of activity corresponding to different behaviors. The findings suggest that astrocytes may store memories as 'fingerprints' in specific areas, called hotspot maps.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalScience Advances·TypeExperimental study·DateFeb 9, 2022

UCI study reveals neurobiological processes occurring during puberty that trigger sex differences in learning and memory

Research finds prepubescent female rodents outperform males in hippocampal long-term potentiation and spatial learning, reversing after puberty. The study proposes optimal teaching strategies should adapt to brain differences between sexes during this critical life stage.

SourceUniversity of California - Irvine·JournalNature Neuroscience·TypeExperimental study·DateFeb 9, 2022

Researchers report cognitive effects of aerobic exercise on persons with significant memory loss caused by traumatic brain injury

Researchers found that moderate aerobic cycling improved auditory verbal learning and processing speed, as well as increased volumes of the hippocampus and cerebellar cortex. The study suggests exercise interventions may be an attractive option for improving cognitive function in individuals with traumatic brain injury.

SourceKessler Foundation·JournalNeurocase·TypeRandomized controlled/clinical trial·DateJan 24, 2022

Mass production of revolutionary computer memory moves closer with ULTRARAM™ on silicon wafers for the first time

Researchers have successfully demonstrated ULTRARAM¼trade mark computer memory on silicon wafers for the first time, combining non-volatility with speed and energy-efficiency. The technology outperforms previous incarnations, offering data storage times of at least 1000 years and fast switching speeds.

SourceLancaster University·JournalAdvanced Electronic Materials·TypeExperimental study·DateJan 6, 2022

Scientists pick up the 'slack' on describing the brain networks behind motor function

A new study by Ritsumeikan University reveals that whole-body dynamic balance training increases brain connectivity and improves motor learning. The research found significant changes in brain activity associated with offline learning, opening up new avenues for studying neural networks during natural tasks.

SourceRitsumeikan University·JournalMedicine & Science in Sports & Exercise·TypeExperimental study·DateNov 22, 2021

Balancing fear

The insular cortex processes both positive and negative emotions and receives information from the body, including heart rate and breathing. In mice, the brain uses bodily signals to regulate fear, keeping it within a healthy range.

SourceMax-Planck-Gesellschaft·JournalScience·TypeExperimental study·DateNov 18, 2021

Blood plasma protein fibrinogen interacts directly with nerve cells to cause brain inflammation

A USF Health study reveals that fibrinogen can directly interact with neurons, leading to inflammation and neurodegeneration in Alzheimer's disease and traumatic brain injury. The researchers found that blocking the binding of fibrinogen to its receptors may alleviate short-term memory problems associated with these diseases.

SourceUniversity of South Florida (USF Health)·JournalBiomolecules·TypeExperimental study·DateNov 8, 2021

Infrared light therapy might aid dementia patients

A pilot study found improvements in memory, motor function, and processing skills in healthy individuals after receiving transcranial photobiomodulation therapy. The therapy, involving infrared light, has the potential to alleviate nerve cell damage and reduce symptoms of dementia.

SourceDurham University·JournalPhotobiomodulation Photomedicine and Laser Surgery·TypeRandomized controlled/clinical trial·DateOct 18, 2021

How our past shapes the present

A study published in Nature Communications demonstrates how the brain constructs the present moment through recent past experiences. The researchers discovered that brief stimuli leave a trace in the brain for almost a minute, accumulating biases in perception that allow subjects to fine-tune their sensory channels over time.

SourceScuola Internazionale Superiore di Studi Avanzati·JournalNature Communications·TypeExperimental study·DateOct 15, 2021

Research reveals drug targets for memory enhancement

A Bristol-led research team has identified specific receptors for the neurotransmitter acetylcholine that re-route information flowing through memory circuits in the hippocampus. The discovery holds promise for developing new, safer treatments for conditions like Alzheimer's disease and schizophrenia.

SourceUniversity of Bristol·JournalNature Communications·TypeObservational study·DateSep 16, 2021

Scientists invent a new information storage and processing device

Researchers at New York University created a new type of memory that stores and processes information similar to synapses and neurons in the brain. The device combines the unique properties of quantum materials with spintronic magnetic devices, offering promising advancements in artificial intelligence and neuromorphic computing.

SourceNew York University·JournalScientific Reports·TypeExperimental study·DateJul 29, 2021

A more robust memory device for AI systems

Researchers developed a new magnetic memory device using antiferromagnetic materials, offering improved scalability, write speed, and security. The device's unique structure allows for simultaneous writing and reading of data, addressing key challenges in high-performance AI applications.

SourceNorthwestern University·JournalNature Communications·DateJun 22, 2021