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Science News Archive April 2016 - Page 30


Page 30 of 39

Improving models of chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) researchers have improved their models of the disease by understanding how cancer cells differentiate into antibody-secreting plasma cells in mice. Patient-derived T cells play a crucial role in this process, and therapies promoting differentiation may offer new treatment options for CLL.

SourceJCI Journals·JournalJCI Insight·DateApr 7, 2016

Kidneys have an innate clock that affects many metabolic processes in the body

A study found that kidneys possess an innate circadian clock regulating various functions, including urine formation and excretion, which adapt to daily light-dark cycles. This internal clock also influences the levels of amino acids and lipids in the blood and affects drug elimination in individuals taking medications.

SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateApr 7, 2016

Protein SIRT5 linked to healthy heart function

A new study by Cornell University researchers identifies protein SIRT5 as a key player in maintaining healthy heart function. The study found that SIRT5 can remove harmful protein modifications, allowing the heart to burn fatty acids more efficiently. This discovery could lead to new therapies for cardiomyopathy and improved lifespan.

SourceCornell University·JournalProceedings of the National Academy of Sciences·DateApr 7, 2016

Heavy drinking endangers the health of liver transplants

New research reveals that heavy drinking after liver transplantation can cause significant damage to newly transplanted livers, leading to severe health issues. Early alcohol assessments and multidisciplinary interventions are crucial to prevent relapse and ensure patient success.

SourceWiley·JournalLiver Transplantation·DateApr 7, 2016

Review examines functioning, disability, and health in autistic patients

The review provides clarity on assessing functional abilities and disabilities in autistic patients, shedding light on the complexities of autism spectrum disorder. Key findings highlight the importance of understanding ability and disability in individuals of all ages, allowing for more effective diagnosis and treatment.

SourceWiley·JournalAutism Research·DateApr 7, 2016

Penn study brings new understanding to how fundamental DNA sequences govern gene activity

Researchers from Penn School of Medicine shed light on how DNA sequences called enhancers govern gene activity, influencing which genes are 'on' or 'off' in each type of cell. They found that pioneer factors help expose DNA to regulatory proteins, allowing enhancers to activate genes and promote normal cell functions.

HPV vaccine effective in youth with kidney disease, but less so in those with a kidney transplant

A recent study found that HPV vaccination stimulates robust immune responses in girls and young women with chronic kidney disease and dialysis, but less optimal responses among those with a kidney transplant. This highlights the need for additional research to protect kidney transplant recipients from HPV infections.

SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateApr 7, 2016