Researchers find a long-overlooked molecular machine in the cell nucleus, the spliceosome, that produces mutant gene/protein fueling cancerous cells. Targeting this protein with existing and developing drugs may offer new treatment options for aggressive leukemia.
A new study reveals a strong connection between global warming and rising economic disparities worldwide. The research, led by Noah S. Diffenbaugh and Marshall Burke, suggests that long-term climate change has decreased economic growth in poor countries while increasing it in wealthy nations.
Researchers at Mass Eye and Ear have identified microglia as gatekeepers that orchestrate inflammatory responses in the retina during autoimmune uveitis. By depleting microglia, disease was completely blocked, suggesting a novel therapeutic target for this devastating eye disease.
Researchers created hydrogels that mimic muscle properties through mechanical training, producing strong, soft, and fatigue-resistant materials for medical implants and engineering applications. The trained hydrogels demonstrate improved tensile strength, soft flexibility, and high water content.
A new Iowa State University study found that rurality, education, and race significantly predicted the change from Democrat to Republican in Iowa. White, rural voters without a college education were more likely to switch to Republican. The research counters the narrative that economic anxiety was the reason for this shift.
Researchers at Tokyo Institute of Technology have discovered a way to make submicron-sized cylinders disappear using optical frequency illumination. This breakthrough could lead to new kinds of detectors and sensors for the medical and aerospace industries, without the need for expensive metamaterial coatings.
This study found that drinking water is associated with reduced calorie intake from sugary beverages. Not drinking water was linked to consuming an average of 93 extra calories and 4.5% more sugar among participants aged 2-19, with variations by age and racial/ethnic groups.
A new study published in the Journal of the American College of Cardiology found that a preschool health program significantly increased healthy habit awareness among children from an underserved community. The program resulted in a 2.2-fold higher score on overall knowledge, attitudes and habits towards a healthy lifestyle.
Researchers have identified three medicinal plants from Mauritius with effective inhibitors of esophageal cancer cells, stopping their growth and contributing to their death. The extracts contain natural chemical compounds that restrain the G2/M stages transition in malignant tumor cells by activating AMPK signaling pathway.
In a study published in Physical Review Letters, researchers reveal that repulsive interactions between Cooper pairs themselves hold them in check in insulating materials. This finding could lead to new manipulation methods for superconducting devices and the design of novel electronic components.
Researchers developed precision-guided anticancer nanoparticles that effectively target peritoneal cancer cells, reducing side effects. The use of guiding molecules improves drug solubility, selectivity, and release in tumor cells.
Researchers developed a new snake-inspired soft robot using programmable kirigami metamaterials, enabling responsive surfaces and smart skins. The robot can now change its shape in response to programmed sequences of pop-ups, improving speed and accuracy.
The survey found that nearly half of American workplaces, including small employers, now offer some level of health promotion or wellness programs. Comprehensive workplace health promotion programs are more common in larger employers with a budget, experience, and assigned responsibility.
A study by MIT neuroscientists found that a genetic mutation linked to Williams Syndrome leads to thinning of the fatty layer that insulates neurons. Reversing this effect with drugs improved symptoms, suggesting a new direction for treatment.
Researchers reconstructed Greenland Ice Sheet mass changes from 1972 to 2018 using data on ice velocity, thickness, and surface elevation. The study found a significant increase in ice loss, with an average of 290 Gt per year during 2010-2018, contributing to a 13.7 mm rise in global sea level.
Researchers found that slime molds can store knowledge of salty environments through absorption, allowing for up to a month of retention. The study suggests that the substance itself supports the slime mold's memory, rather than just the environment.
Researchers found that treating patients with personalized, combination therapies improved response rates and overall survival in patients with therapy-resistant cancers. Highly matched patients showed a 50% response rate compared to unmatched or less well-matched patients.
A study found that increasing physical activity can eliminate the association between sedentary behavior and increased mortality risk. Replacing sitting with standing or vigorous physical activity was more consistently associated with risk reduction in high sitters.
A study by Johns Hopkins Medicine researcher Junaid Razzak found a 6% increase in deaths due to emergency conditions between 1990 and 2015. The mortality burden was highest in low-income countries, with injuries, heart attacks, lung infections, and strokes being the top causes.
A new study by Harvard Medical School researchers found that nearly half of older adults who start dialysis die within a year, with death rates being almost twice as high as previously reported statistics. The study's results can help inform patient decisions and physician choice of treatment for end-stage kidney disease.
Researchers developed FitRec, a deep learning tool that analyzes past performance to predict speed and heart rate. The tool identifies important features affecting workout performance and recommends alternate routes for runners to achieve specific target heart rates.
Ten ASU engineering faculty members have received NSF CAREER Awards to fund their research projects, totaling $5 million over five years. The awards support various specialties, including nanoscale assembly and solar energy conversion.
A recent study found that 40.3% of people with cancer used marijuana in the past year, compared to 38.0% without cancer. Meanwhile, prescription opioid use was higher among those with cancer (13.9%) than without (6.4%).
A multinational study led by Vanderbilt University researchers has found that diabetes has reached epidemic proportions in Asia, dramatically increasing the risk of premature death, especially among women and middle-aged people. The study highlights the urgent need for tailored diabetes management programs for Asian populations.
Columbia engineers develop a nano-coating of boron nitride to stabilize solid electrolytes in lithium metal batteries, increasing battery life while ensuring safety. The new method achieves record-thin protection layers without lowering energy density.
Researchers from FEFU and international partners discover potential targets for glioblastoma multiforme treatment by studying proteins in the WNT signaling pathway. The findings could lead to improved antitumor therapy outcome through suppression of cancer stem cells, accelerating tumor growth rate.
A study published in Plastic and Reconstructive Surgery found that obese patients do not have a higher risk of complications after abdominoplasty, also known as tummy tuck surgery. The study included 82 patients who underwent the procedure over a seven-year period, with similar complication rates between obese and non-obese patients.
A new study found that plant-based diets can lower the risk of heart failure in adults without known heart disease, while Southern diets are linked to higher risk. The study examined five dietary patterns and their association with incident heart failure hospitalizations.
Researchers at Columbia University have discovered a new family of gravitational instabilities in granular particles, where lighter grains rise through heavier grains like 'fingers' and 'bubbles'. This phenomenon sheds light on geological processes and has potential applications in pharmaceutical production and carbon capture.
Researchers from the University of Surrey argue that a switch to permanent daylight saving time would undermine the sleep benefits of delaying school start times. This could lead to inadequate levels of sleep among teenagers, despite efforts to improve their health and graduation rates.
A recent study by Duan et al. has shown that human influence on climate change can be traced back to the late 19th century based on summer-winter temperature difference. The amplitude of seasonal temperature fluctuations has been decreasing widely, and this trend can be traced back to the 1860s.
A study found that exercise-induced cognitive improvements can be inherited by offspring via sperm. Exercise has been shown to increase the growth of immature neurons and improve mitochondrial function in the brain, leading to enhanced memory performance.
Researchers have identified two microRNA family members that can provide both immediate and long-term protection against heart damage. The therapy targets the miR-19a/b microRNAs, which regulate proliferation of cardiomyocytes and reduce inflammation, leading to improved heart function.
A deep-learning model developed using serial image scans of tumors from patients with non-small cell lung cancer (NSCLC) predicted treatment response and survival outcomes better than standard clinical parameters. The model's performance improved with the addition of each follow-up scan, predicting two-year survival with an accuracy of...
A study by Ohio State University found that customers left more negative remarks on comment cards on rainy days than dry days. The researchers linked this to bad moods, which were related to less positive views about the restaurants visited.
Researchers from Moscow Institute of Physics and Technology have found superinjection to be possible in homostructures, composed of a single material. This enables the creation of mass market devices, such as ultraviolet LEDs thousands of times brighter than previously thought possible.
Marine Skin, a polymer-based material with integrated electronics, revolutionizes sea life monitoring by tracking movement and diving behavior, as well as environmental health. The system can operate at unprecedented depths, with enhanced sensitivity, and plans include additional sensing capabilities.
A recent study found that mixing different cultivars of St. Augustinegrass reduced fall armyworm infestations in lawns. The researchers discovered that the caterpillars preferred single-variety plantings, but when multiple cultivars were planted together, it created a more pest-resistant lawn.
Researchers found curcumin has potential to prevent or treat stomach cancer by inhibiting histone modifications. Compounds like cholecalciferol, resveratrol and quercetin also show promise in modulating histone activity.
A Mount Sinai study shows that preschool intervention can improve healthy lifestyle habits in young children, with 12% increase in knowledge and attitudes towards a healthy lifestyle. The intervention group also showed improved behaviors in physical activity, diet, and emotional management.
A large Australian study has identified key factors contributing to poor mental health among bisexual individuals, including relationships with straight partners and negative self-perceptions. The research highlights a significant need for support and education to improve the mental well-being of bisexual Australians.
New research by Albert Kao and Iain Couzin found that information loss due to modular groups can actually enhance accuracy, especially in complex environments. This challenges previous assumptions about the benefits of free-flowing communication among group members.
A La Trobe University study has found that wildlife restores itself after bushfires, but the surrounding habitat determines which species survive. The research highlights the importance of considering landscape context when planning strategic burns to protect native wildlife.
Researchers at NTU have developed a sustainable method to increase seed oil yield in crops such as canola, soybean and sunflower. The new genetic modification involves modifying the key protein Wrinkled1, resulting in larger oil reserves in seeds, which could lead to higher economic gain and increased production of biofuel.
Researchers successfully produce bulk quantities of well-isolated single nanowires of TMM, which are only 3 atoms wide in diameter and 50 times longer than previous attempts. The team finds that isolated nanowires exhibit unique mechanical properties, including twisting when perturbed.
Jasper Heinsbroek, a recent MUSC graduate, receives the DP5 award to pursue independent addiction research and develop new therapeutics. The grant will enable him to establish himself as an independent researcher and follow up on his doctoral research.
A new study by Bocconi University's Alexander Kentikelenis and colleagues finds that IMF loans' structural reforms weaken states' ability to regulate the economy. The research highlights how privatization, price deregulation, and public sector job cuts compromise state capacity, hindering sustainable growth.
The study examined the privacy practices of popular apps for depression and smoking cessation, assessing both policy disclosures and actual data sharing. Researchers found that 36 apps shared user data with commercial third parties despite inadequate privacy policies.
A team of scientists has identified a novel lignin gene, Zm4CL1, that controls the maize bm5 mutant with reduced lignin content. The study reveals increased forage digestibility and cell wall saccharification efficiency in the bm5 mutant.
Research from the University of Illinois Chicago shows that pharmacies closing leads to decreased adherence to heart medications like statins and beta-blockers. People living in low-access neighborhoods or using independent pharmacies are most affected.
Researchers identified UNC45A as a key player in cancer cell proliferation and tumor growth. Inhibiting UNC45A was found to decrease cancer cell proliferation and cause mitotic catastrophe, leading to cell death.
A study by Florida State University found Airbnb's exponential growth is devoureding hotel revenues and driving down room prices and occupancy rates. The company's listings have grown over 100% a year, significantly affecting hotels' room prices and revenues.
A KAIST research team created a microfluidic-based drug screening chip that identifies synergistic interactions between two antibiotics in just eight hours. This technology can aid in exploring critical pharmacological patterns of antibiotic interactions and guide clinical therapies.
A new workflow combines genome annotation with undergraduate education, providing efficient training for both researchers and students. The framework uses a set of logical steps to begin an undergraduate annotation program, resulting in high-quality genome annotations and valuable skills for future careers.
The study reveals that restoration of marsh vegetation is crucial for overall recovery after the Deepwater Horizon oil spill. The research found that planting foundation species like Spartina alterniflora can facilitate colonization by burrowing invertebrates and fuel the food web, leading to a faster recovery.
The organic cathode offers more reliable contact with the electrolyte, extending cycle life and allowing for higher energy density. The flexibility of the organic cathode maintains intimate contact at the interface even as the cathode expands and contracts during cycling.
A team at Vanderbilt University is developing 'safe harbor' standards of care based on scientific evidence to reduce defensive medicine and its consequences. The project aims to lower healthcare costs, improve quality of care, and decrease patient exposure to radiation.
Researchers from HSE University and London Business School analyzed Russian companies' stock prices and found profitable arbitrage deals with minimal risk. The 'buy-and-hold' strategy tends to generate higher returns than conversion strategies, despite being riskier.
Researchers found that light-intensity physical activity is associated with larger brain volume and healthy brain aging. The study suggests that achieving even moderate levels of physical activity may be beneficial for preventing dementia.
A University of Kansas researcher is developing technology to monitor and prevent overheating in lithium-ion batteries using machine-learning approaches. The goal is to improve the thermal safety of these batteries, which are increasingly used in various industries and applications.