Researchers found a significant increase in opioid-use disorder hospitalizations among patients with common rheumatic conditions like gout, osteoarthritis, and fibromyalgia. The study suggests that these patients are at risk of developing an opioid use disorder due to chronic musculoskeletal diseases.
Researchers have gained insights into how nanoparticles can be used to identify invasive microbes and deliver targeted treatments, potentially preventing deadly diseases contracted on medical equipment. The study, conducted by Monash University researchers, found that nanoparticles bound to fungal cells but were non-toxic to them.
A new study found that biologics improve clinical disease activity in both elderly-onset and young-onset rheumatoid arthritis patients similarly at 48 weeks. The researchers also discovered similar drug maintenance and adverse event discontinuation rates between the two age groups.
Researchers have successfully demonstrated how machine-learning tools can improve the stability of light beams' size for experiments by adjusting parameters that largely cancel out fluctuations. The technique has been shown to reduce beam width errors from a few percent down to 0.4 percent, with submicron precision.
Researchers have created EphaGen software to provide a straight answer to whether a patient has a mutation. The new method uses a novel evaluation approach to assess the reliability of 'no mutation' results, enabling doctors to make informed decisions.
A new study used data from over 5 million people to develop equations predicting the five-year risk of reduced estimated glomerular filtration rate (eGFR), a key indicator of chronic kidney disease. The findings can help identify individuals at increased risk and potentially prevent or manage the condition.
A diagnostic study found a protein involved in managing bacteria to be a reliable biomarker for the noninvasive detection of NEC. Elevated levels of intestinal alkaline phosphatase (iAP) protein linked to NEC were shed in stool samples, with accuracy rates of 97% and 76% for severe and suspected NEC, respectively.
Researchers develop a new technique to detect activated complement pathway in patients with thrombotic microangiopathies (TMA), allowing clinicians to determine potential use of existing treatment for other diseases. The technique could lead to improved diagnosis and treatment of secondary TMAs, such as pre-eclampsia and HELLP syndrome.
Researchers at the University of Copenhagen have discovered that stress hormones, such as corticosterone, play a crucial role in controlling the circadian rhythm of brain cells. By using test rats and a new method involving medical micropumps, they were able to restore the rhythmic activity of clock genes in the cerebellum even after t...
Researchers develop a method to create bio-inspired horns from horse tail hairs and silk, mimicking the structure and properties of real rhino horn. The goal is to undermine demand for endangered rhino horns and provide a cheaper alternative.
Scientists at UVA have developed a new method to determine the genetic causes of diseases by analyzing the effects of genes on proteins. The technique, using plant extracts, enables researchers to sort immediate from complex reactions, revolutionizing gene function study.
A high-caloric diet alters the time-of-day dependent metabolic cycle in mice, suggesting lean and obese patients may respond differently to steroid therapy. The study also highlights the biological function of daily hormone secretion cycles and their impact on sugar and fat storage or release by the liver.
Matmo strengthened from a tropical storm to a storm with hurricane-force in the overnight hours of Nov. 7, according to NASA-NOAA's Suomi NPP satellite imagery. The Joint Typhoon Warning Center predicts Matmo to make landfall near the border of India and Bangladesh on Saturday, Nov. 9.
The discovery of Peregocetus pacificus, an amphibious whale from middle Eocene deposits in Peru, provides evidence of the earliest known quadrupedal whales crossing the South Atlantic from Africa to South America. The fossil specimen reveals webbed feet and terrestrial locomotion abilities, dating back over 40 million years.
A new study has estimated the growth rates of deep-sea coral communities in Hawaii, revealing a pattern of ecological succession over centuries to millennia. The research found that Coralliidae, pink coral, were the first to colonize, followed by Isididae, bamboo coral, and Antipatharia, black coral.
Researchers tested an Automated Wearable Artificial Kidney (AWAK) device for effective toxin removal in patients with kidney failure. The study found no serious adverse events, improving portability and flexibility of treatment.
A recent study published in Neurology reveals that individuals with multiple sclerosis (MS) who also suffer from depression are more likely to experience debilitating symptoms earlier than those without depression. The research highlights the need for early recognition and treatment of depressive symptoms in patients with MS.
Several high-impact clinical trials have yielded promising results, including the ATHENA trial showing azathioprine to be as effective as mycophenolate mofetil in preventing chronic kidney rejection, and the NOBILITY trial demonstrating that obinutuzumab improves kidney health in patients with lupus nephritis. Additionally, a phase 3 s...
A small study published in Pain Reports found that immersive VR scenes of Arctic exploration can reduce perceived ongoing pain and sensitivity to painful stimuli. The researchers believe that VR may trigger the body's own pain-fighting systems, leading to a decrease in chronic pain symptoms.
Two new studies found that vaginal delivery and exclusive breastfeeding may reduce the risk of developing allergic conditions in children. Meanwhile, a mother's diet during pregnancy and history of allergies can also influence eczema and food allergy development in offspring.
A NASA-funded study reveals that winter carbon dioxide loss from the Arctic permafrost region could increase by 41% over the next century if greenhouse gas emissions continue at their current pace. This would mark a stark reversal for the Arctic, which has captured and stored carbon for tens of thousands of years.
Researchers Karen Culcasi and Cynthia Gorman examine how international laws formed after WWI contributed to today's hostile climate for refugees. They found that the creation of new countries, nationalism, and the establishment of international governance entities like the League of Nations shaped refugee law.
Researchers at EPFL developed a simple and inexpensive AI-based system to predict where and when lightning will strike, using standard meteorological data. The method has been proven correct almost 80% of the time and offers a new way to predict complex phenomena like lightning strikes.
Researchers propose a new theory on how massive, spinning black holes form near supermassive black holes at the centers of active galactic nuclei. This 'Pac-Man-like' behavior offers a natural explanation for high-mass binary black hole mergers and could help understand galaxy growth.
Researchers found that allergy shots significantly improved PFAS symptoms in 11 out of 20 surveyed children, with no reported worsening. The treatment showed promise for kids receiving allergy shots and suffering from PFAS.
Researchers from Leibniz Institute for Tropospheric Research found that vertical air motions increase ice formation in mixed-phase clouds. This correlation has important implications for understanding the water cycle and predicting precipitation.
Allergists warn that social media misinformation can lead to incorrect medical decisions for people with food allergies. Dr. David Stukus notes that online 'cures' and at-home testing are often unproven and misleading, while reputable sources should be consulted instead.
A new sphenisciform fossil from New Zealand further resolves the bauplan of extinct giant penguins, characterized by elongated beaks and longer hindlimbs. The fossil, found in the North Island, provides key insights into the diversity of ancient penguin species.
Researchers found budesonide reduced serious side effects like new onset diabetes and bone loss in liver transplant patients, while maintaining comparable organ rejection rates to prednisone. The study involved 20 patients and showed lower infection rates and improved blood sugar control.
The study demonstrates simultaneous control over transport and spin properties of cold atoms, enabling the exploration of spintronics and solid-state physics. The efficiency of the atomic spin filter matches that of equivalent electronic systems, opening up new perspectives for studying quantum transport dynamics.
A three-year clinical study found that reducing uric acid levels with the generic drug allopurinol did not slow diabetic kidney disease progression in type 1 diabetes patients. The study's conclusions provided a clear answer to an important scientific question, while suggesting further research may be needed.
A new study found that copper hospital beds in ICUs harbor 95% fewer bacteria than traditional beds, maintaining low-risk levels throughout patient stays. This could lead to improved patient outcomes, lives saved, and healthcare cost savings.
A pilot study by Kessler Foundation researchers found that children with moderate-to-severe traumatic brain injury have impaired social communication skills, leading to poorer social functioning. The study suggests the Social Communication Disorders Checklist (SCDC) has potential for screening children with TBI.
Researchers at Trinity College Dublin have made a breakthrough in finding catalysts for renewable energy production. They discovered new molecules that can increase the efficiency of water splitting, reducing the
A compound developed by Johns Hopkins researchers has been shown to slow tumor growth, alter the tumor microenvironment, and promote durable and highly active anti-tumor T cells. The drug, a prodrug version of glutamine antagonist DON, was designed to target cancer cells' high demand for glutamine.
A new study from Cincinnati Children's Hospital Medical Center reveals that many teenagers who undergo bariatric surgery experience low iron and B12 levels years later. Regular nutrition check-ups and supplementation can minimize these risks, emphasizing the importance of annual assessments.
A new genetic mapping system for polyploid species has been developed in Brazil, allowing researchers to analyze the genes of complex organisms like sugarcane, kiwi, and blueberry. The open-source software package, MAPpoly, can be downloaded free of charge and has already been adopted by researchers at seven institutions worldwide.
Tropical Storm Halong weakened and transitioned into an extra-tropical cyclone as tracked by NASA-NOAA's Suomi NPP satellite on November 8. The storm had maximum sustained winds of 60 knots and was moving east-northeast at 24 knots.
Oral health risks for older adults include increased incidence of tooth decay, gum disease, and complete loss of teeth. Practicing good oral hygiene, using fluoride treatments, and getting regular dental care can help prevent these complications.
Typhoon Nakri intensified into a stronger typhoon after satellite imagery showed better organization and increased winds, moving westward towards Vietnam. The Joint Typhoon Warning Center expects landfall on Nov. 10 or 11, near Danang.
A new study published in the journal Nutrients found that glutamates such as monosodium glutamate (MSG) can be used to reduce sodium in the food supply. The substitution of glutamates for salt can reduce sodium intake by up to 7-8 percent, according to the study. This finding is consistent with previous research and dietary guidelines ...
Researchers investigated the effect of vitamin D and omega-3 supplements on chronic kidney disease (CKD) development or progression in adults with type 2 diabetes. The study found no significant difference in CKD progression between supplementation groups.
A new study found that most primary care doctors discuss the importance of exercise with African American female patients but fail to address hair care's role. Dr. Sophia Tolliver suggests incorporating hairstyling assessments into office visits to help overcome barriers to exercise.
Scientists at The Wistar Institute have developed a synthetic DNA-based platform to drive in vivo production of broadly neutralizing anti-HIV antibodies. These results show that the platform can produce potent antibodies with strong neutralization ability, comparable to recombinant antibodies. Additionally, combining multiple antibodie...
A new study found that eroding permafrost coastlines in the Arctic can release significant quantities of carbon dioxide, potentially exacerbating climate change. The research simulated erosion effects in a lab experiment and found CO2 was released as rapidly from thawing permafrost in seawater as it is from thawing permafrost on land.
Researchers have developed a new method to test the rheology of complex liquids, such as gelled desserts, using ultrasonic spinning rheometry. This updated method can capture time-dependent properties and has applications in chemical engineering, civil engineering, and cosmetics.
A record number of bushfires are raging on Australia's east coast, spanning across New South Wales and Queensland. The fires, fueled by hot and dry weather, have burned over 365,000 hectares, with temperatures expected to remain high for the next week.
Scientists designed a novel approach to create stable and predictable antibody drug conjugates (ADCs) using computational docking molecular simulations. The new therapy, called MAGNET-ADC, can deliver cancer drugs specifically to tumor tissue with reduced toxicity.
A new analysis found that 21% of adolescents and 32% of young adults used prescription opioids in the past year. Misuse rates were higher among young adults, with 57% obtaining them from friends or relatives. The study highlights the importance of screening for opioid use in this vulnerable population.
A multi-institutional study found that adolescents with Type 2 diabetes experienced improved hyperfiltration and reduced elevated urine albumin-to-creatinine ratio after gastric bypass surgery compared to adults. In contrast, adults with pre-existing diabetes did not show significant improvements until five years post-surgery.
A massive collaborative research incubator will develop trials for Alzheimer's disease interventions, funded by the National Institute on Aging. Regenstrief researchers will lead a two-year junior career development program to train researchers in embedded pragmatic clinical trials.
Researchers at Universitat Autonoma de Barcelona developed an optimal procedure to identify clusters of identically prepared quantum systems, solving the challenge of sorting quantum data. The new protocol outperforms classical strategies, particularly for large dimensional data.
A recent study by the American College of Allergy and Asthma found that most pediatric allergy patients are satisfied with telemedicine visits for allergies and asthma. Among surveyed parents, 37% were more satisfied, while 63% reported equal satisfaction, indicating a positive experience with telemedicine appointments.
A new diagnostic/treatment algorithm complements early guidance from the CDC for managing vaping product use associated lung injury (EVALI). The tool was developed by pulmonary and toxicology experts at the University of Rochester Medical Center and the New York State Department of Health.
A study published in the journal Science of Learning found that children's brains function similarly regardless of their gender when it comes to math skills. The research team, led by Jessica Cantlon, used functional MRI to compare brain activity in young girls and boys while watching educational videos on early math topics.
A study published in the Journal of the American Geriatrics Society found that interferon-free direct-acting antivirals are effective in treating hepatitis C in older adults, with high cure rates reported despite comorbid conditions. The treatment offers similar effectiveness as it does in younger patients.
Researchers at the University of Illinois are developing a smartphone-based diagnostic system that can detect pathogens in less than 30 minutes using a single drop of blood. The system, which will be handheld and cost less than $10, has the potential to provide fast and affordable results for patients in developing countries.
Researchers at Shenyang Institute of Automation develop contact aerial manipulator system for safe and efficient high-rise building inspection. The robot can avoid obstacles, jump over grooves, and conduct interactive operations while in flight.
A new study published in International Journal of Epidemiology found a strong association between air pollution and carotid intima-media thickness (CIMT) in peri-urban South India. People exposed to higher levels of fine particles had a higher CIMT index, indicating a higher risk of cardiovascular diseases.
A new risk calculator tool predicts accurate five-year risk of chronic kidney disease based on variables like age, hypertension, and diabetes status. The tool enables healthcare providers to identify patients at high risk and benefit from preventive interventions.