A liquid formulation called LATTE has been shown to kill liver cancer cells and potentiate chemotherapy treatments in mice, rabbits, pigs, and human tumor samples. The treatment could provide a safer alternative to traditional methods like thermal ablation, which can be resource-intensive and damage surrounding tissues.
New research reveals large groups tend to think alike, adopting popular categories even when presented with contradictory information. The study also explores how bots can manipulate public opinion, leading to the spread of erroneous ideas.
Researchers have developed a three-step method to reverse significant reforestation side effects, including rapid soil water loss due to fast-growing species. The approach involves reconstructing slopes and planting slow-growing tree species alongside fast-growing species to increase soil water content.
Researchers have developed a pen-like sensor that changes color in response to harmful gases, offering a potential solution for detecting toxic vapors. The device can identify nerve agents and volatile amine vapors, with applications in food safety, environmental monitoring, and public safety.
A large-scale survey of over 80,000 adolescents reveals that non-school friendships are more strongly associated with deviant behaviors and alcohol use compared to in-school friendships. Participants with non-school friends also tended to be engaged with their schools and play central roles in their peer groups.
Inherited genetic variation plays a role in who responds best to checkpoint inhibitors, which release the immune system's brakes. The study identified 22 regions or genes with significant effects on the immune system's response to cancer.
A study published in Food and Chemical Toxicology found that some energy drinks have adverse effects on the muscle cells of the heart. Cardiomyocytes exposed to these beverages showed an increased beat rate and other factors affecting cardiac function.
Researchers found that higher lung ultrasound scores correlated with increased risk of ICU admission, intubation, and death in severe COVID-19 patients. The study used a scoring protocol covering 12 lung regions to predict patient outcomes.
Researchers have used cosmological observations to constrain a quantum gravity model, disproving the linear version. The quadratic model is placed under tighter scrutiny, with stricter bounds compared to quantum experiments.
Immunologists at the University of Freiburg have solved a mystery about how Rituximab, an anti-cancer drug, targets B tumor cells. The researchers found that CD20 organizes nanostructures on the B cell membrane, and its absence or binding to Rituximab activates resting B cells.
A study found that Brazil's average air conditioning equipment days of use would increase by over 100% in a 4°C warming scenario, significantly impacting space cooling needs. The country's energy consumption and CO2 emissions are projected to rise substantially even in more optimistic future warming scenarios.
Researchers at the University of Southern Denmark have developed a new effective antibiotic to combat resistant bacteria, which are becoming increasingly difficult to treat. The substance, from the pleuromutilin class, fights multiple types of resistant bacteria via a unique mechanism of action.
Researchers at the University of Colorado Boulder have designed liquid crystals with complex symmetry structures, similar to those found in minerals and gems. The breakthrough could lead to new types of smart windows and displays with enhanced energy efficiency.
A team of veterinarians from RUDN University tested a complex preparation called gentaminoseleferon to treat respiratory infection in calves. The study showed that the treatment reduced inflammatory processes and promoted active recovery of metabolism, indicating its therapeutic efficiency.
A new tool called CORAL guides clinicians through diagnostic evaluations of patients with COVID-19 symptoms, allowing for safe discontinuation of isolation. The tool was developed to minimize the chance of false-negative test results and reduce hospitalization time.
Researchers found that vegetables in U.S. Department of Agriculture's 'dark green' category were often included in product names, but their average order in the ingredient list was close to fourth. Fruits, particularly juice and juice concentrates, were less likely to appear in product names despite being more prominent in the ingredie...
Scientists at RIKEN Center for Biosystems Dynamics Research have identified a population of hair follicle stem cells and developed a recipe for normal cyclical regeneration. In the study, 81% of bioengineered hair follicles generated in NFFSE medium went through at least three hair cycles and produced normal hair.
Scientists observed disulphide bridge formation in ribosomal exit tunnel during protein synthesis, challenging previous assumptions. The discovery sheds new light on the causes of lens opacities and cataracts, a leading cause of vision loss worldwide.
A new study by researchers from Linköping University suggests that long-term stress is a risk factor for heart attacks. Cortisol levels in hair samples were found to be statistically significantly higher in individuals who suffered a heart attack, even after adjusting for other cardiovascular risk factors.
A single strain of Bacteroides fragilis significantly reduced graft-versus-host disease by protecting gut integrity, according to a proof-of-concept study. The bacteria increased overall gut microbial diversity and reduced donor T cell proliferation, which triggers GVHD.
A new study published in Diabetes Care found that children with Type 1 Diabetes have lower brain volumes and IQ scores compared to non-diabetic children. The research suggests that hyperglycemia may adversely affect brain development, starting from childhood.
A recent study found that drinking one or more cups of caffeinated coffee per day is associated with a decreased long-term heart failure risk. The analysis revealed a significant decrease in heart failure risk over time, ranging from 5-12% per cup per day of coffee consumption.
Researchers found a 15% reduction in total nitrogen losses, 14% reduction in total phosphorus losses, and 39% reduction in sediment losses through crop reallocation simulations. This approach could be a potential path to restoring the Chesapeake Bay.
A new study reveals that wolves have evolved specific ambushing tactics to catch and kill beavers by exploiting their poor eyesight and well-developed sense of smell. Researchers found that 89-94% of ambushing sites were downwind, allowing wolves to remain undetected.
A University of Miami-led team is expanding its pilot program to detect SARS-CoV-2 in wastewater, allowing for early warning systems and potential prevention of transmission. The two-year grant will also enable the team to collect and standardize data from institutions across the US, creating models to predict COVID-19 outbreaks.
Physicists at the University of Bath have developed a way to use resonance to store light energy more effectively in microresonators. This leads to the creation of rainbow-like structures called frequency combs, which can be used for precise measurements and applications such as pollution monitoring and radar technology
A study found patients with dementia twice as likely to contract COVID-19 and experience worse outcomes. African Americans with dementia faced a near-threefold higher risk of infection. The researchers emphasized the need for strategies balancing safety from COVID-19 with protection from social isolation and health-related harms.
The Drosophila headcase gene regulates adult progenitor cell development, including metamorphosis, by controlling growth, proliferation, survival and resistance to stress. It maintains an equilibrium between hormone-stimulated growth control and the stress response.
Researchers are studying ways to reduce waste in the seafood industry by using market incentives, with a focus on Mexico's SmartFish program. The study found that while the model improved sustainability, it also introduced new points of waste, including plastic packaging.
Researchers successfully localized a non-repeating fast radio burst (FRB) using a novel processing system and supercomputer. The breakthrough identified the source location as a galaxy about 3.6 billion light-years away, providing valuable insights into FRBs and their possible causes.
Researchers have mapped the orbit of a rare Nitrogen-rich Wolf-Rayet star in the WR 133 binary system, marking the first-ever visually observed orbit of this type. The team determined the dynamical mass of both stars, with the WN star having 9.3 times more mass than our Sun.
Researchers at NYU Tandon and NYSF have developed a system to sculpt bone tissue with features smaller than a single protein, opening doors for disease modeling, cell research, and targeted therapies. The technology could revolutionize drug discovery and develop better orthopedic implants.
A study by University of Barcelona researchers reveals a new molecular mechanism controlling anaphylactic reaction severity, identifying the KARS gene mutation as a key player. This discovery holds promise for identifying patients at risk and developing prophylactic measures.
Researchers found porous surfaces accelerate evaporation, reducing virus survival time to three hours on paper and two days on cloth. This suggests that covering impermeable surfaces with porous materials can help prevent infection transmission.
A new study from the University of Minnesota Medical School found that Pap test samples can detect proteins also present in ovarian cancer tumor tissues. This discovery suggests potential biomarker candidates for early detection of ovarian cancer, which currently has no early warning system.
Scientists reveal that the African Coelacanth gained 62 new genes through encounters with other species, which arose from transposons. The genes likely play a role in gene regulation and are tissue-specific, with evidence suggesting they were introduced multiple times throughout evolutionary history.
Researchers at UCLA Jonsson Comprehensive Cancer Center identified a new approach combining an anti-psychotic drug, a statin and radiation to improve overall survival in mice with glioblastoma. The triple combination extended median survival 4-fold compared to radiation alone, providing hope for improved treatment options.
Researchers found that grid-tied solar photovoltaic (PV) owners are undercompensated in most of the U.S., as the value of solar eclipses net metering and two-tiered rates. This study provides a generalized model to evaluate the economics of grid-tied PV systems, showing substantial future regulatory reform is needed.
A new study found that 70% of variability in deal proneness is associated with genetic factors, highlighting the existence of a heritable component. The research compared identical and fraternal twins, revealing stronger similarities in deal-proneness among identical twins.
Research reveals that regions of the human genome with unusual DNA folding tend to have higher mutation rates than others. The study found that non-B DNA sequences, which can fold into different conformations, play a major role in determining regional variation in mutation rates across the genome.
A recent study examined SARS-CoV-2 infection rates among migrant workers in Singapore. The findings suggest that the virus is widespread among this population, highlighting concerns about workforce health and safety.
Metal-containing diagnostic agents can detect early AD markers and synchrotron-independent, long-lived. They may improve access to AD imaging for risk groups, offering a solution to the current limitations of PET, MRI, and SPECT imaging.
A new study by Oregon State University suggests that marching band members in leadership roles experience more neck and upper back discomfort, while less experienced bandmates are more prone to left-hand pain and cognitive strain. The findings also show that gender has no impact on discomfort levels or perception of workload.
Researchers found that smartphone PPG technology can accurately measure blood-oxygen levels and heart rate, comparable to FDA-approved hospital instruments. This technology could enhance remote monitoring of patients with chronic cardiopulmonary disease and initial treatment for respiratory viral pandemics.
A new study found that elderly patients with locally advanced esophageal and esophagogastric junction cancer can achieve similar outcomes as younger patients when receiving recommended multimodal therapy. The therapy regimen includes initial chemoradiotherapy followed by surgical resection.
The University of Texas at El Paso received a $1 million National Nuclear Security Administration grant to train underrepresented students in the energy industry. Through this program, UTEP students will gain skills and training to compete for jobs in nuclear energy, with opportunities for internships and research projects.
Researchers discovered ancient Amazonian farmers built wooden palisades and earthworks to enclose valuable soils in Bolivia. This fortification demonstrates the importance of protecting investments in fertile land during social unrest.
A longitudinal study by Florida Atlantic University found that children with mean friends experience increased relationship negativity, while those with nice friends report declining negativity. Prosocial behaviors can mitigate hurt feelings and promote conflict resolution.
Scientists have developed a light-activated protein that can study single synapses in neurons, revolutionizing the understanding of long-term potentiation. The discovery reveals the physical changes in dendritic spines during long-term potentiation, providing valuable insights into learning and memory.
New Yorkers' acceptance of the Covid-19 vaccine has significantly increased under the Biden Administration, with 64% reporting they would take it in January, up from 55% in September. Disparities persist across racial and ethnic groups, but the largest increase was seen among Black respondents. The survey also found that employed indiv...
Research finds cheap herbal cigarettes and bidis are widely available online, often with unverified health claims, and may act as a gateway to conventional tobacco products. The study calls for urgent regulation of their sale and marketing.
Two scientists urge health agencies to invest in vaccine development based on broadly neutralizing antibodies against multiple virus variants and strains. This approach could provide immunity against emerging pandemics and serve as a pan-virus solution for prevention and treatment.
COVID-19 technology responses face challenges of personal safety, privacy, and control. Experts like Katina Michael emphasize the importance of sociotechnical systems that engage users in their design. Implementing these systems correctly requires coordination, listening, and public involvement.
A new study by archaeologists at the Florida Museum of Natural History found that a handheld color-matching gadget often misread colors readily distinguished by the human eye. The device, known as the X-Rite Capsure, failed to produce correct color scores in 37.5% of cases when tested against a book of color chips.
Researchers developed an intervention based on illeism, referring to oneself in the third person, to improve wisdom-centric approach to conflict resolution. The 'distanced-self-reflection' diary method showed effectiveness in changing people's wise reasoning about personally challenging interactions.
A study by Princeton University researchers found that relaxed control measures during the summer months are the biggest factor driving wintertime COVID-19 outbreaks. Climate and population immunity play smaller roles in the current pandemic phase.
A study led by Anglia Ruskin University found that farmers in the Brazilian Amazon can develop strong connections with nature, regardless of their knowledge of local bird species. The research involved 227 farmers and showed a complex relationship between ecological knowledge and nature connection.
Researchers at Umeå University have quantified carbon emissions from rivers and lakes in Western Siberia, finding that emission rates are high and exceed carbon export to the Arctic Ocean. The study highlights the importance of inland waters in the global carbon cycle and climate system.
A new study found that nanomaterials can bind strongly to microorganisms, entering the food chain and accumulating in organs like the brain. The use of nanomaterials is challenging to regulate because of their small size, making it difficult to assess their possible risk.
A new drug, ProAgio, has been shown to be effective in treating pancreatic cancer and prolonging survival in mice. It works by inducing apoptosis in cancer-associated fibroblasts, reducing the dense stroma that protects tumors from immune systems and conventional drugs.