The proton therapy cohort of NRG-BN001 demonstrated improved overall survival (OS) for patients with newly diagnosed glioblastoma, with a 6.8% absolute survival advantage at 2 years. The results support the development of a phase III randomized trial to confirm these findings.
ECMWF is poised to unveil a new phase in its data sharing strategy, providing the complete ECMWF Real-time Catalogue under a Creative Commons licence. The organization will make its forecast data free and open at a 25 km resolution in real time with no latency, starting from October 1st.
A new study analyzing over 460,000 children and adolescents found a more than double risk of developing long COVID after a second COVID-19 infection. The study highlights the importance of vaccination and preventive measures to reduce this risk.
A study of 27,500 people found that poor sleep leads to brains appearing older than their actual age. Low-grade inflammation is estimated to explain around 10% of the link between poor sleep and older brain age.
A patient-reported outcomes analysis suggests that twice-daily radiation is associated with better quality of life and longer survival compared to once-daily radiation in patients with limited-stage small cell lung cancer. The study found less clinically meaningful decline in quality of life among those receiving twice-daily radiation.
Researchers found a significant increase in AMPA receptors across Long COVID patients' brains, correlating with cognitive impairment severity. This discovery provides a direct biological explanation for brain fog symptoms and may lead to novel treatments.
The new emulator Effort.jl allows researchers to analyze complex data sets faster and more efficiently than ever before. It uses state-of-the-art numerical methods and clever preprocessing strategies to achieve exceptional computational performance, making it possible to explore cosmic scenarios without waiting hours for each simulation.
Researchers at Sylvester Comprehensive Cancer Center are pioneering innovative approaches to treating complex movement disorders with advanced imaging and radiosurgery techniques. The new era of functional radiosurgery enables precise treatment without invasive procedures.
A comprehensive study by UC Riverside's School of Public Policy found that agricultural conservation programs saved water at a low cost per acre-foot, while new supply efforts were more expensive. The analysis showed that 80% of the Colorado River's water is consumed by agriculture, and incentive programs can deliver meaningful savings.
Researchers found that feeling in control over everyday stressors can lead to a 62% increase in resolving the issue. The relationship strengthens with age, suggesting that controlling one's sense of control can be a resource for managing daily life and impact health outcomes.
Researchers at the University of Illinois Grainger College of Engineering have developed a single-step battery cathode recycling process that simultaneously extracts metals from old cathodes and creates new ones. The method outperforms existing techniques in terms of economic efficiency, environmental impact, resource usage, and human ...
Researchers discovered seals can detect size differences of just 17.6mm between vortex rings, helping them identify fish escape directions. This ability may allow seals to outmaneuver fleeing fish.
The new Python-based framework simplifies climate dynamics, allowing students and researchers to explore cutting-edge experiments. It features adjustable atmospheric settings and can simulate real-world influences, making it suitable for classroom exercises and advanced research.
A new platform developed by researchers from the University of Illinois demonstrates the utility of a ytterbium-171 atom array in quantum networking. The work represents a key step toward long distance quantum communication and has promising implications for modular quantum computation.
A study of 676 patients who experienced out-of-hospital cardiac arrest found that neurological outcomes were similar regardless of socioeconomic background. However, lower-income areas had lower bystander CPR rates, suggesting disparities in pre-hospital care.
A Virginia Tech oncologist is championing a precise approach to treating acute myeloid leukemia by tracking subtle molecular changes in patients. His work aims to identify signs of potential relapse and tailor treatment for each individual with this rare blood cancer.
Glypican-3 is a key driver of hepatocellular carcinoma progression, facilitating metastasis and tumor microenvironment remodeling. Immunotherapy targeting GPC3 has shown preliminary safety and antitumor activity in clinical trials, with ongoing research focusing on optimized patient selection and disease monitoring.
Risk factors for portal vein thrombosis (PVT) in liver cirrhosis include hemodynamic disturbances, vascular endothelial injury with hypercoagulable states, severity of cirrhosis, and thrombophilic genetic factors. Early identification and timely intervention are crucial to improve prognosis.
Researchers at The Hebrew University of Jerusalem have developed a binder-free method for 3D printing silica glass using light to trigger a chemical reaction. This breakthrough enables custom, high-performance glass components that were previously impossible to manufacture.
Researchers used ATR-FTIR spectroscopy to analyze tissue samples from patients with metaplastic breast carcinoma, ductal carcinoma in situ, and invasive ductal carcinoma. The study found that specific spectral features were significantly elevated in carcinomatous tissues and could effectively differentiate between normal tissue and can...
A new study found that children who prefer pickled, smoked, and fried foods are more likely to have asthma. In contrast, seafood preference appears to reduce asthma risk among normal-weight children. The findings highlight the importance of early-life dietary habits in shaping respiratory health.
The new API helps compliance teams quickly identify potential areas of concern and streamline reviews, strengthening oversight and safeguarding funding and reputations. It enables the review of researchers and collaborators with structured data that supports efficient workflows.
Children's belief that family and friends will support their pursuit of political leadership predicts their expressed motivation to become leaders. Girls show stronger relationship between anticipated social support and interest in becoming leaders compared to boys. The study suggests communicating social support for girls' political a...
A decade-long study found that children with early-developed empathy were more likely to experience anxiety and depression during the Israel-Hamas war, highlighting the dual role of empathy in mental health. The research suggests that empathy can be both a strength and a vulnerability in the face of mass trauma.
A new AI tool called Waldo can scan social media data to discover personal reports of harmful side effects of popular health products. The tool achieved an accuracy of 99.7% in detecting adverse events, outperforming general-purpose chatbots.
The study reveals that balance is key in engineering cells to produce more chemicals without antibiotics or complex methods. The team designed genetic circuits using negative feedback systems to optimize cell factories, increasing function by threefold and cumulative chemical production over time.
A new study examines the radiology department's experience during a mass casualty terror attack in southern Israel. Researchers found that rapid staff mobilization, versatile imaging resources management, and AI-enabled safety checks were crucial in guiding clinical decisions.
A panel of experts recommends considering hormone replacement therapy for breast cancer survivors with severe menopausal symptoms, citing the need for more patient-centered care. The study suggests that HRT may be safe and beneficial for many women, particularly those with low-risk disease, while minimizing the risk of relapse.
The Brain & Behavior Research Foundation has awarded 165 Young Investigator Grants worth $11.4 million to support early-career scientists in mental health research. The grants will focus on depression, schizophrenia, anxiety, PTSD, addiction, and other brain and behavior disorders.
The US Naval Research Laboratory has installed a state-of-the-art cluster system for growing and analyzing quantum materials at the atomic level. This allows researchers to study materials one layer at a time, eliminating the need for sample transfer and reducing contamination risk.
Researchers identified specific ways to address religion and spirituality during radiation therapy, highlighting their importance in patient coping mechanisms. The study found that nearly all patients considered spiritual history questions helpful, especially those related to coping with stress.
The CityUHK team is developing two core therapeutic medicines using state-of-the-art DNA surgery technology to treat liver and cardiovascular genetic diseases. Their approach offers a durable and long-lasting solution, eliminating the need for repeated medications.
The IPBES report highlights five strategies to achieve transformative change: incorporating culture and ecology into conservation efforts, integrating biodiversity concerns into economic sectors, reforming governments, shifting societal values, and promoting incremental changes. The authors emphasize the urgent need for concerted effor...
The study highlights how wind farms have transformed rural landscapes, disrupting local agricultural markets and eroding rural identities. The research calls for a more participatory and place-based energy transition that respects local heritage and democratic governance.
Researchers have developed a novel coating with controllable crack structure that enables efficient evaporation, pollutant degradation, and mechanical stability. The coating achieves high evaporation rates and effective purification of seawater, with a removal rate of over 99% for pollutants.
A recent study published in Social Development found that firstborn behavioral problems can predict the quality of their sibling relationship over time. Maternal reflective functioning plays a crucial role in mitigating negative outcomes, particularly for children exhibiting internalizing behavioral problems. The researchers suggest th...
A study surveyed gamers about video game effects, finding that 78% of respondents experienced altered lives through meaningful gaming experiences. These experiences often involved rich storytelling, which inspired self-reflection and identity building. The study's findings highlight the importance of designing games that promote positi...
Researchers at Shinshu University developed a novel copper-cobalt oxide composite that excels in energy storage, environmental remediation and water splitting. The material boasts high specific capacitance, exceptional stability and numerous active catalytic sites, making it a promising low-cost alternative to conventional catalysts.
Researchers found that tolcapone increases behavioral control in individuals with AUD by activating the prefrontal cortex, which is consistent with the drug's effects on dopamine levels. The study suggests a new mechanism for treating AUD beyond current medications that target the brain's reward system.
The TORF Research Unit studies medieval North Frisia's tidal flats, revealing archaeological remains and understanding human-environment interactions. Researchers aim to reconstruct the region's complex history and raise public awareness of coastline risks.
A new clinical model integrating CT signatures predicts HCC risk more accurately than existing models, stratifying patients into high-risk and low-risk groups. The study enhances individualized surveillance and improves patient outcomes for cirrhosis patients.
Researchers create nanoscale slots to tune phonon vibrations, enabling ultrastrong coupling and hybrid quantum states in lead halide perovskite. This breakthrough could improve energy flow and performance in optoelectronics.
Researchers developed an advanced survey system combining AR glasses with a camera and AI to objectively assess leafminer damage in the field. The DeepLab-Leafminer model achieved superior segmentation performance, resulting in high diagnosis accuracy rates.
This qualitative study of home-delivered nutrition services for older adults found meaningful benefits beyond their stated purpose, supporting funding for the Older Americans Act Nutrition Program. The program achieved its intended outcomes and yielded positive results for participants.
A KAIST research team has developed a Frequency Switching Neuristor that autonomously adjusts its response characteristics, like the brain's intrinsic plasticity. The device achieves 27.7% less energy consumption than conventional neural networks and can compensate for partial circuit failures to resume normal operation.
The Red Sea experienced a massive disruption 6.2 million years ago, completely changing its marine life and transforming into a barren salt desert. The catastrophic flood from the Indian Ocean rapidly refilled the basin, restoring normal marine conditions within less than 100,000 years.
A new photodiode design using germanium-ion-implanted silicon overcomes trade-offs in existing power monitors for on-chip light monitoring, enabling faster processing speeds and higher energy efficiency. The device demonstrates high responsivity and low dark current, making it suitable for integration into photonic circuits.
Researchers at Fox Chase Cancer Center demonstrate that pulsed low dose rate (PLDR) chemoradiation therapy can significantly reduce severe side effects, such as painful swallowing problems, while maintaining treatment effectiveness for patients with esophageal and non-small cell lung cancer. The study's key findings show that PLDR brea...
The American Counseling Association has launched the Counseling Compact, enabling thousands of professional counselors to practice across state lines. This mutual recognition model allows counselors to work in person or via telehealth, providing access to mental health services for millions of Americans.
Researchers at Washington State University have discovered that altering brain function in the cerebellum region can ease physical and emotional symptoms of alcohol withdrawal. The study used genetic tools and a synthetic compound to achieve this, offering a promising new approach to treating alcohol use disorder.
The startup has assessed over 3,400 miles of Indiana roads using advanced computer vision algorithms to quickly and objectively assess pavement conditions. This platform provides actionable insights without requiring in-house data analysis expertise or costly hardware.
A study by Israeli researchers found that people apply mechanisms of forgiveness towards technology, similar to human relationships. Participants described their experiences with technological malfunctions in emotional terms, describing paths to forgiveness such as cost-benefit calculation, placing responsibility on humans, and accepti...
The study reveals that MRAP2 fundamentally alters the localisation and behaviour of brain receptor MC4R within cells, facilitating appetite-suppressing signals. This new understanding holds the potential to develop effective treatments for obesity and related metabolic disorders.
A new Concordia-led study links algal blooms in Canadian lakes to both nutrient pollution from agricultural runoff and climate change. The research, using DNA sequencing of lakebed microbes, found that these two drivers amplify each other in ways that profoundly affect lake ecosystems.
Serum HBV RNA and HBcrAg have emerged as promising biomarkers for chronic hepatitis B, enabling better monitoring of disease progression, treatment response, and risk stratification. These markers provide a window into intrahepatic viral activity, correlating with clinical outcomes such as HCC development and liver fibrosis severity.
A recent survey of 919 UK adults who received botulinum toxin injections found alarming differences in the quality of care and advice given. Despite existing requirements for qualified prescribers, many participants reported not receiving written consent forms or being informed of potential complications.
A phase 1B clinical trial found that combining avelumab with whole brain radiotherapy provides a safe and effective treatment option for patients with leptomeningeal disease, with 67% of patients alive three months after treatment. The study also showed an adaptive immune response to treatment, reducing levels of regulatory T cells.
Research presented at the European Emergency Medicine Congress finds that doctors and nurses are more accurate than AI in triaging patients in emergency departments. While AI showed some promise in flagging critical cases, its overall accuracy was lower than clinicians' across most metrics.
Colin Hill joins C-Path's Board of Directors with experience in AI, drug development, and translational acceleration. He aims to bring precision medicine focus to advance treatments worldwide.
Researchers at UMass Amherst have created an artificial neuron with electrical functions that mirror those of biological neurons. The low-powered protein nanowire, made from bacteria, enables efficient communication between living cells and could lead to the development of new bio-inspired computers.