The study found that a specific spinal circuit is involved in both ejaculation and arousal, and integrates sensory inputs to adjust its output based on the animal's internal state. The researchers also discovered that Gal⁺ neurons receive sensory input from the penis and can trigger ejaculation, but their effects are suppressed by brai...
A study found that lactate IV infusion increases brain-rejuvenating hormone BDNF levels in the bloodstream, similar to those after high-intensity exercise. The hormone promotes nerve cell growth and survival. Researchers suggest moderate exercise may be necessary for optimal benefits.
A 2023 MSU graduate's undergraduate research project uncovered a new, 95-million-year-old crocodyliform named Thikarisuchus xenodentes. This tiny creature lived on land, feasting on plants and insects, with unique teeth that shed light on ancient ecosystems and evolutionary patterns.
A recent study by the University of Waterloo found that routine blood samples can provide early warnings for spinal cord injury patient outcomes. The research team used machine learning to analyze hospital data from over 2,600 patients and discovered patterns in common blood measurements that could forecast recovery and injury severity.
Researchers from USTC deciphered the temperature-governed processes of lithium-mars gas batteries, finding that temperature regulates a balance between two-electron and four-electron processes. Low temperatures cause interface passivation, while high temperatures stimulate decomposition efficiency through the generation of highly activ...
A collaboration among HKU and Nanjing University detected millisecond pulsations hidden within a gamma-ray burst, revealing the birth of a millisecond magnetar. The findings provide the clearest evidence yet that magnetars can power some of the most luminous explosions in the universe.
Researchers introduce a new theoretical framework that accounts for higher-order spatial harmonics in gradient metasurfaces, enabling precise control over inter-unit coupling. This allows for unprecedented harmonic-selective control in devices, with applications in ultra-dense beamforming and reconfigurable multichannel sensing.
Macrophage lysosomes regulate reactive oxygen and nitrogen species production, with pH influencing the balance between killing microbes and avoiding self-harm. The study provides insights into immune regulation using nanoelectrochemical sensors.
Researchers from USTC synthesize monolayer WS2 lateral homojunctions with tailored defect architectures, enabling controllable direct chemical vapor deposition growth. The structures exhibit distinct field-effect characteristics and demonstrate rail-to-rail operation in logic inverters.
Researchers uncover pierced shells and pigments from Châtelperronian period, indicating a genuine workshop for jewellery manufacture. The findings suggest long-distance trade networks or significant human mobility, shedding new light on cultural variability of the time.
The new serum amyloid A (SAA) assay demonstrated high reproducibility and broad linear measurement range, suitable for low-grade to high-level inflammatory states. Its strong agreement with established methods supports its adoption in routine diagnostics.
Researchers explore natural enzymatic alternatives to chemical oxidants in wheat-based foods, revealing the catalytic roles of sulfhydryl oxidase, protein disulfide isomerase, and other enzymes. These endogenous enzymes improve gluten cross-linking, elasticity, and sensory qualities.
Researchers develop one-molecule, self-regulated 'bilateral anchoring' for high-performance rigid and flexible PSCs, achieving record efficiencies while extending device lifetime under real-world stress. The innovative design enables commercial viability of squaric acid as a single-component modifier for stable PSCs on any substrate.
Researchers applied epibrassinolide to accelerate berry coloration, increase anthocyanin content, enhance sugar accumulation, and promote softening. The study reveals that plant steroid hormones orchestrate grape ripening through coordinated regulation of secondary metabolism, hormone cross-talk, and cell-wall dynamics.
Researchers have created a new class of lipid nanoparticles (LNPs) with complex internal arrangements, expanding their potential for carrying small-molecule drugs, proteins, metal ions, and mRNA. The breakthrough offers flexibility in designing delivery systems for different therapeutic molecules.
A review explores how blood-based metabolomics can provide objective biomarkers for depressive states, suicidal ideation, and treatment responsiveness in depression. Metabolites such as 3-hydroxybutyrate and citrate have shown reproducible associations with depressive severity across multiple clinical cohorts.
A study comparing immunoblot assays and ELISA for detecting anti-F-actin antibodies in autoimmune hepatitis type 1 reveals comparable accuracy, with immunoblotting providing higher specificity. The findings suggest that immunoblot assays could be a reliable alternative to ELISA for diagnostic purposes, but larger studies are needed.
Researchers have uncovered how immune cell metabolism shifts to drive fibrotic processes through TGF-β/SMAD3 and AMPK-PPARγ pathways. Metabolic reprogramming also plays a role in drug resistance, highlighting the need for early diagnosis and personalized treatment.
Researchers discovered that ultrafast magnetization switching proceeds with a speed of about 2000 meters per second, not uniformly throughout the material. A moving boundary propagates through the film, sweeping through the entire layer in roughly 4.5 ps.
A new study published in JAMA Surgery found that parathyroidectomy significantly reduces the risk of developing diabetes by 30% in patients with primary hyperparathyroidism. The study analyzed over 3,100 adult patients and tracked their development of diabetes for nearly three years.
New antibody treatments for Alzheimer's disease show promise in slowing progression, but high costs, complex testing, and suboptimal care hinder their potential. Experts call for coordinated global action to reform healthcare systems, public policy, and societal attitudes.
A University of Otago study found that most young people don't follow current sleep guidelines, with only a quarter exercising before bed. The research suggests that these recommendations may not be practical or effective in improving sleep.
A survey of 1091 US music fans found that 6 in 10 have experienced inappropriate sexual behavior at a live gig, with women more than twice as likely to be affected. The most common barriers to reporting incidents were feeling the incident wouldn't be taken seriously or knowing who to report it to.
A new review study reveals that PFAS are entering farmland soils through waste recycling and wastewater reuse, raising concerns for food safety. The study found that biosolids are the primary source of PFAS in agricultural soils, with soybeans showing particularly high burdens.
Researchers have developed a low-cost material that can clean antibiotics out of water, using steel sludge as a valuable resource. The biochar breaks down tetracycline through chemical reactions, removing over 85% in just two hours.
Researchers develop multifunctional aerogels combining thermal insulation, flame retardancy, and mechanical robustness using bio-based nanocellulose. The resulting aerogels exhibit low thermal conductivity, high flame resistance, and impressive strength and flexibility.
The study analyzed 10 federal health surveys and found that most included sexual orientation questions, but only one survey asked about differences of sex development. Standardized measures would help identify disparities and track progress in primary care research and practice.
EPB Quantum℠ adds hybrid computing to its platform, enabling the analysis of trillions of operational data points from EPB's electric system. The new project aims to minimize electrical losses and voltage drops in power grids, enhancing reliability and capacity.
A UC Irvine-led study reveals that indoor surfaces act as massive chemical sponges, absorbing volatile organic compounds for extended periods. Regular ventilation alone may not be sufficient to remove these contaminants, highlighting the importance of physical cleaning activities.
Pharmacy technicians alleviate clinicians' and nurses' workload by handling medication tasks, reducing pain points in medication access work. The study found that technicians improved perceptions of quality of care and patient access, with significant reductions in burden and task time.
A new PET tracer, 64Cu-NOTA-EV-F(ab′2), has been developed for same-day imaging of triple-negative breast and urothelial bladder cancers. The tracer exhibits rapid tumor accumulation and high specificity in nectin-4 positive tumors, enabling accurate non-invasive visualization of this protein.
Interdisciplinary primary care teams in Oregon's Project Nurture and Nurture Oregon model deliver comprehensive substance use disorder care to pregnant individuals. These teams perform medical, behavioral health, and coordination functions, providing social support, advocacy, and quality improvement activities.
Researchers discovered a cobalt-catalyzed anti-Markovnikov hydrosilylation reaction of terminal alkynes with tertiary silanes using a dinuclear cobalt carbonyl complex coordinated by the bidentate phosphine ligand Xantphos. The catalyst achieves excellent β/α selectivity and exhibits good compatibility with functional groups.
A Penn State Health project reframes quality metrics to present patient-oriented outcomes in plain language, improving provider engagement. The initiative resulted in clear and relevant reports, increased motivation among providers, and a stronger sense of impact.
Dr. Brandon M. McElroy, MD, joins Ochsner Novant Health's 65 Plus program in Bellview, bringing nearly a decade of experience in primary care to the community. The program offers customized healthcare, social support, and wellness resources tailored to the unique needs of older adults.
A Cornell University study reveals that warming climate is the primary driver of rangeland degradation, surpassing the impact of herd size. Climate change has a significant effect on rangeland productivity, with even year-to-year variations in weather having a much bigger impact than herd size.
A new study published in Cell found that relying on stand-in reference DNA from similar but different species can significantly distort research findings for vulnerable species. Using the wrong genome can miss up to a third of genetic variations and lead to misleading conservation decisions.
A recent study suggests that a near-collision between two protoplanets of similar masses could have formed Mercury, contradicting the widely accepted theory. The researchers used smoothed particle hydrodynamics to simulate this event and found that it can reproduce Mercury's composition with high precision.
A yeast commonly found in the gut, Candida albicans, can make salmonella infections worse by binding to bacteria and triggering a chain reaction that allows it to invade cells. Removing Candida's ability to create arginine, an amino acid involved in protein synthesis, also reduces salmonella's ability to infect.
The study introduced an Epic electronic health record workflow to auto-order preventive and chronic disease tests for complex older adults. This approach has improved patient engagement, reduced post-visit results communication, and minimized cancellations.
Researchers increased Medicare wellness visit completion from 8.4% to 50.8% in nine months by scheduling combined visits with patients' regular clinicians, leading to lower no-show rates and increased screenings for various health issues.
This study found that combining Medicare wellness visits with problem-based visits increased the completion of annual wellness visits by 50.8% and reduced no-show rates by 11.9%. The combined visits also led to an increase in screenings, tests, and vaccines ordered, including for depression, falls, pain, and cancer screening.
The Chatbot Assessment Reporting Tool (CHART) statement outlines 12 key reporting items for chatbot health advice studies, providing a checklist and methodological diagram. This guideline supports stakeholders in reporting, understanding, and interpreting the findings of such studies.
Private equity hospitals reduce staffing, leading to increased patient transfers, shortened ICU stays, and higher ED mortality. This results in decreased capacity to deliver care, with reduced salary expenditures per bed day for emergency departments and ICUs.
Researchers at Hebrew SeniorLife discovered a U-shaped relationship between home ambient temperature and self-reported attention difficulty in older adults. Attention was optimal between 20°C and 24°C, with worsening difficulties outside this range.
A USC study found that most unsheltered Angelenos face significant gaps in accessing basic needs such as food, water, and hygiene. The research revealed that less than a quarter of participants had access to a toilet, and over half ate fewer than one meal per day.
A new study by George Mason University found that maintaining dental care habits is associated with better overall health, including more frequent eye and physical exams, healthier habits, and higher ratings of overall well-being. The research also explored the complex relationship between anxiety and dental care-seeking behavior.
A study analyzed antibiotic prescribing patterns in Arkansas Medicaid's patient-centered medical home (PCMH) program. The results showed a decrease in pediatric and adult age group claims, with clinics that prescribed the least antibiotics having lower rates in 2021 compared to previous years.
A Georgia State University researcher has received a $25,000 grant to develop mechanisms for treating obesity and related metabolic dysfunctions. The goal is to identify therapeutic candidates with strong clinical translation capabilities.
A study found that ultrasound-guided IUD insertion is faster than conventional methods, reducing procedure time by an average of seconds. Despite this, pain levels were not significantly different between the two groups.
A study of 4,905 US early-career family physicians found that those with higher educational debt tended to work more hours per week and were more likely to report burnout symptoms. Physicians working over 60 hours a week were nearly three times more likely to experience burnout.
A University of Delaware-led research team has developed a new type of catalyst that enhances conversion of plastic waste into liquid fuels more quickly and with fewer undesired byproducts. The catalyst achieves reaction rates nearly two times faster than those previously reported, producing targeted production of liquid fuels while mi...
A 16-year study found increasing patient complexity and fewer patients seen by family physicians in Alberta, Canada, with notable changes including higher proportions of older adults and those with multiple chronic conditions. This trend has significant implications for primary care access and workforce planning.
A nationwide study found patient death rates increased in emergency departments of U.S. hospitals acquired by private equity firms, with staffing cuts and salary reductions proposed as likely explanations. The researchers also found transfers of patients to other hospitals and shortened stays in intensive care units.
A 'light-touch' EHR referral strategy successfully connected patients with prediabetes to community-based DPPs, with 122 out of 577 referred patients enrolling. The strategy was used by 30% of targeted clinicians and accounted for over half of all referrals.
After ACA, usual source of care increased from 67% to 68%, with gains in low-income rural and urban areas. Insurance barriers decreased, while accessibility and individual preferences improved for low- and middle-income adults.
The Rice WaTER Institute hosted the Water Nexus Conference 2025, bringing together industry, policy, and research experts to discuss integrated approaches for safe and reliable water systems. Key findings include the need for innovative technologies, capital structuring, and operational efficiency to close the growing funding gap in wa...
A pre-visit questionnaire with EHR integration significantly improved family history documentation, with 16.1% of patients having new entries within 30 days. This approach also supported personalized prevention and referrals, including screening recommendations and lifestyle advice.
Researchers at UT Dallas discovered a connection between chronic sickle cell disease pain and the bacteria present in the gastrointestinal tract. By transplanting beneficial bacteria into mice with sickle cell disease, they alleviated chronic pain, highlighting the role of gut microbiomes in driving chronic pain.
A new study published in JAMA Network Open shows that regular phone support after losing weight is crucial for maintaining weight loss. Participants who received monthly phone calls maintained an average of 8% weight loss from their starting weight, with about 60% keeping off at least 5% of their initial weight.