The SCAI Door to Lactate Clearance Cardiogenic Shock Initiative aims to improve outcomes in cardiogenic shock by using lactate clearance as a practical solution. Measuring lactate at diagnosis and every 2-3 hours can guide early management decisions.
Two new species of black bass, Bartram’s and Altamaha bass, have been documented by UGA ecologists. These fish have distinctive physical characteristics, such as patterned dark brown blotches on their sides and carmine-red eyes with a black pupil ringed by a thin gold margin.
Researchers at the University of Würzburg have discovered that boron can form π complexes with olefins, similar to transition metals, opening up new possibilities for industrial catalytic processes. The finding aims to replace toxic and costly heavy metals with main group elements.
The University of Arizona and University of New Mexico received a $43.6 million NIH grant to support translational science and training for early-career researchers. The partnership aims to translate research discoveries into improved patient care, with a focus on substance use disorders and rural health initiatives.
An international research team used 300-million-year-old fossilised droppings to better understand molecular fossilisation, revealing how tiny grains of iron carbonate preserved delicate molecular traces. The findings add a new dimension to understanding molecular preservation and its implications for reconstructing ancient ecosystems.
Researchers found that glioblastoma cells in clusters are less deadly than those that disperse from these clusters. The dispersed cells are more plastic and resistant to therapy, making them a major contributor to treatment resistance and poor patient outcomes.
The STIM tool assesses online adverts for risks of human trafficking, helping law enforcement and charities identify potential victims. The tool has already led to multiple arrests and safeguarded dozens of vulnerable people.
Researchers at the University of Liverpool have discovered a groundbreaking new class of antibiotics called Novltex, which targets lipid II in bacterial cell walls. This innovative approach offers potent and durable protection against multidrug-resistant bacteria, addressing one of the biggest challenges in modern medicine.
Research confirms bidirectional relationship between long COVID and menstrual disorders, with symptoms intensifying during perimenstrual phases. The study suggests an inflammatory reaction as the underlying cause, paving the way for new therapeutic prospects tailored to women.
Researchers from UMD found that cats can survive bird flu if treated promptly with oseltamivir, a common influenza treatment. Early intervention significantly increases the chances of survival and strong protection against reinfection for several months.
Researchers at UNSW have made a significant advance in quantum computing by creating 'quantum entangled states' using the spins of two atomic nuclei. This breakthrough enables the potential to build large-scale quantum computers using existing technology and manufacturing processes.
Researchers developed a novel genome editing approach called 'append editing' by mimicking the natural bacterial defense system against viruses. This method enables precise genetic modifications in bacteria, plants, and human cells with high accuracy and minimal disruption.
The WMO report reveals that 2024 was marked by severe drought in the Amazon basin and Southern Africa, while Central Europe experienced excessive rainfall, leading to devastating floods. Glaciers globally lost 450 billion metric tons of ice, accelerating climate change impacts.
A team of animal behavior experts found that Gifted Word Learner dogs can distinguish between toys used for tugging versus fetching, even when the toys don't share any obvious physical similarities. The dogs were able to remember those categorizations for long periods without prior training.
Research from Texas McCombs reveals that trust-based messages delivered by credible sources increase the likelihood of women seeking life-saving exams. Peer-empowering messages led to the largest increase in adoption, challenging traditional strategies of relying on infographics or factual information.
New research finds that 86% of parents in New Zealand disclose their child's donor conception to them by age 18, with most sharing the information before age 10. Heterosexual couples are less likely to share this info, but same-sex couples and single women have higher disclosure rates.
The latest gravitational wave observation reveals two black holes with masses 30 times that of the Sun, shattering previous expectations. This discovery confirms a longstanding theory by Stephen Hawking and opens new possibilities for testing our understanding of gravity.
A new trial has shown that a lower dose of the immunomodulatory drug ATG is safe and effective in preventing the progression of type 1 diabetes in young people. The study found that the drug was able to arrest or delay the progression of T1D at a dose as low as 0.5mg/kg, with a good safety profile.
Researchers developed four stabilization strategies to improve zinc anode stability in AZIBs, including artificial SEI layers, electrolyte modification, bioinspired designs, and structural optimization. These approaches enhance cycle life, Coulombic efficiency, and overall performance of AZIBs.
A long-term study in Northeast China's fertile black soils found that biochar improves soil health, stabilizes microbial communities, and increases crop yields when applied at the right rate. The optimal application rate enhances microbial stability and organic matter content, leading to better yields.
A new study finds that El Niño increases the likelihood of extreme daily downpours in India's wetter regions, potentially leading to hazardous conditions. The research suggests changes in atmospheric buoyancy and low-pressure system tracks drive this intensification, which has remained steady over time despite regional shifts.
A study published in PLOS Biology found that women from lower-income countries with non-English first languages publish 70% fewer papers than men, while non-native English speakers at early career stages outperform native English speakers. The authors call for an effort to consider these factors when assessing scientists' performance.
Researchers found a significant link between severe pregnancy sickness (hyperemesis gravidarum) and an increased risk of mental health conditions. Women with HG experience anxiety, depression, and postpartum depression, highlighting the need for integrated care across physical and mental health.
The Naval Research Laboratory's Robotic Servicing of Geosynchronous Satellites (RSGS) payload has completed critical space-readiness testing, confirming its ability to withstand thermal vacuum conditions. The system, designed for on-orbit servicing and upgrades, has the potential to transform satellite operations in geosynchronous orbit.
Researchers identified 27 species of bacteria and fungi that collectively increase the risk of pancreatic cancer by 3.5 times. The study analyzed saliva samples from 122,000 healthy individuals and found that boosting the mouth's microbiome may protect against cancer.
A joint research team developed a multi-label classification algorithm to solve the spectral function of one-dimensional Bose gases at arbitrary interaction strengths. The algorithm successfully captured power-law behavior at spectral thresholds, validating nonlinear Luttinger liquid theory predictions.
Ensemble projections suggest vaccinating high-risk groups reduces disease burden, while broader vaccine availability saves more lives. Averted COVID-19 burden due to vaccination is robust across immune escape scenarios.
A new review from the University of Adelaide highlights inconsistencies in Australian crop regulations, affecting the coexistence of genetically modified (GM) and non-GM crops. The current regulatory framework is inadequate, leading to varying standards across different sectors, making it difficult for farmers to ensure compliance.
A large-scale population study found that oxaliplatin benefits only younger stage III patients, with no added survival benefit for those over 70. The study suggests using an age threshold to make evidence-based choices about chemotherapy.
The Ver-A-T1D trial suggests that verapamil could preserve beta-cell function in adults with newly diagnosed type 1 diabetes. The study demonstrated encouraging trends towards beta-cell preservation and well-established safety profile, but narrowly missed statistical significance.
A recent study from Spain aims to develop inclusive medical AI applications by overcoming binary logics and including the needs of trans people. The research team, led by Nataly Buslon Valdez, collaborated with PRISMA association to design AI apps that promote personalized treatments tailored to individual needs.
A recent study analyzing data from the Mexican National Health and Nutrition Surveys (2016-2023) found that cardiovascular disease risk increased in Mexico between 2016 and 2023. The average 10-year CVD risk was estimated at 9.5% using region-specific tools, highlighting the need for accurate models to predict local disease burden.
Researchers analyzed 222 terpene synthase genes in 24 angiosperm species, revealing how specific subfamilies drove the production of diverse terpenes. This study highlights the evolutionary foundation of terpene diversity and its role in plant adaptability and ecological success.
The SURPASS-PEDS trial shows that tirzepatide significantly improves HbA1c levels, BMI, and fasting glucose in children aged 10-17 years with type 2 diabetes. The study demonstrates sustained improvements over a year-long period, making it a potential safe and efficacious treatment option for youth-onset type 2 diabetes.
Researchers discovered that FGF21, a muscle hormone released during exercise, is elevated in people with ALS and may play a protective role. Higher levels of FGF21 were associated with slower disease progression and longer survival in patients.
Researchers at UC San Diego have created a new genetic editing approach that uses small nuclear RNA base editing, which can modify the genetic code with greater precision and safety than CRISPR. This method has the potential to treat various diseases, including neurodegenerative, cardiovascular, and immune disorders.
A new study from the University of Eastern Finland reveals that patients in specialised psychiatric care face a variety of interconnected social risks. The most vulnerable segments of the population experience cumulative risks including financial difficulties, housing challenges, and violence.
Scientists from Institute of Science Tokyo have created a solid electrolyte-based hydrogen battery that stores and releases hydrogen at temperatures below 100 °C, overcoming high-temperature and low-capacity limitations. The battery offers practical solutions for hydrogen-powered vehicles and clean energy systems.
PANoptosis, a hybrid form of cell death, is being explored as a strategy to tackle liver cancer. By integrating apoptosis, pyroptosis, and necroptosis pathways, PANoptosis triggers both direct tumor killing and immune reprogramming.
Researchers are conducting a national study to test the effectiveness of daily atropine drops in delaying and reducing nearsightedness in young children. The study aims to enroll over 600 children aged 6-11 who will receive either atropine or a placebo, with results comparing the timing of onset and progression of myopia.
Researchers developed an AI model that diagnoses achalasia using plain chest X-rays, outperforming physicians' reviews. The diagnostic performance of the AI model demonstrated higher sensitivity and specificity, enabling early diagnosis and potentially improving treatment efficacy.
Researchers identified reconstruction mechanism of copper alloy catalysts during electrochemical CO₂ conversion reactions. The findings provide a 'design map' for understanding and predicting surface reconstruction, enabling the design of dynamic catalysts that adapt during operation.
Recent studies provide insights into the complex role of human activity in the movement and adaptations of Aedes aegypti and Anopheles funestus. The research reveals the urgent need for tailored interventions against malaria and dengue, highlighting the importance of locally tailored control strategies.
Astronomers using the Gemini South telescope have found that asteroid 1998 KY26 is much smaller and spinning faster than previously thought. The asteroid is approximately 11 meters wide and completes a rotation in just five minutes, making it challenging for Hayabusa2 to land on its surface.
Researchers have designed smart nanomedicines that scavenge ROS, re-programme immunity and restore tissue homeostasis to treat chronic inflammation. The work outlines design rules, AI-assisted screening and scalable synthesis for next-generation anti-inflammatory therapeutics.
New evidence suggests that giant spinosaurs, like Spinosaurus, had their roots in Europe. A Spanish species, Camarillasaurus cirugedae, was found to be a close relative of North African spinosaurs.
A new study from Tufts University found nearly one in three young adults skipped dental visits due to cost and lack of insurance coverage. Young adults were more likely to skip medical care, struggle with copays, and report poor mental health or memory problems.
A deep learning model achieved up to 98% accuracy in distinguishing autistic from neurotypical participants, providing clear insights into brain regions most influential to its decisions. The model could benefit autistic people and clinicians by offering accurate and explainable results to inform assessment and support.
A team of researchers at Simon Fraser University has created a new type of silicon-based quantum device controlled by both electricity and light. The breakthrough demonstrates an electrically-injected single-photon source in silicon, clearing a major hurdle for building a scalable quantum computer. This development holds significant po...
Researchers at the University of Copenhagen discovered two new ciliary proteins that regulate cell communication and may lead to the development of new treatments for chronic diseases. The study found that defective cilia can disrupt signaling in almost all tissues and organs, leading to various diseases.
A new study finds that prompt administration of opioid pain relief in emergency departments can reduce hospitalization rates for children with sickle cell disease. Children who received timely first-dose administration within 60 minutes and second-dose administration within 30 minutes showed reduced hospitalization odds.
Researchers used precise neural activity measurements from epilepsy patients to study how brain processes speech. The findings suggest the auditory cortex operates on a fixed, internal timescale independent of speech structures, providing a consistently timed stream of information.
A cohort study reveals oral bacteria and fungi as significant risk factors for pancreatic cancer development. The findings suggest that oral microbiota may serve as biomarkers to identify individuals at high risk of pancreatic cancer, potentially contributing to personalized prevention strategies.
A new clinical guideline has been issued for 18F-flurpiridaz PET myocardial perfusion imaging, providing recommendations for patient selection, imaging protocols, and interpretation of results. The guideline aims to enhance diagnostic accuracy and optimize resource utilization for the evaluation of coronary artery disease.
Researchers have identified 21 bio-inclusions of ancient insect orders and plant fossils in Ecuador's Genoveva quarry, shedding light on a previously unknown ecosystem. The discovery provides a unique snapshot of the Cretaceous era and its biodiversity in the Southern Hemisphere.
A team of researchers analyzed 238 high-oil peanut varieties across China, evaluating their agronomic performance and disease resistance. Key findings revealed a trade-off between oil content and protein levels, with many varieties showing resistance to major diseases but few exhibiting high-level resistance.
A study by the University of Gothenburg found that young individuals place a higher importance on even tooth color, with an average score of 8. White teeth scored 7.25, highlighting the significance of aesthetics in oral health.
A new study reveals the first detailed structure of HvAACT1, a barley root protein that enables plants to tolerate aluminum-rich acidic soils. This breakthrough provides the structural basis for citrate efflux in plants and has implications for designing crops that can withstand difficult conditions.
Researchers investigate the atomic-scale origin of the Invar effect in Fe-Ni alloys, finding that elongated Fe-Fe pairs contribute to volume contraction with increasing temperature. The study reveals a balance between elongating pairs and Curie temperature as a function of Ni content determines the appearance of the Invar effect.
New research shows that music therapy significantly decreases heart rate, systolic blood pressure, and patient-ventilator asynchronies for patients admitted to the cardiac intensive care unit (ICU). Music therapy is a safe, low-cost, non-pharmacological intervention that complements conventional treatments.