Boehringer Ingelheim and EMFRET Analytics have partnered to advance the GPVI-blocking antibody EMA601 for acute stroke treatment. The substance targets platelet surface receptor glycoprotein VI, blocking thrombosis and inflammation while preserving normal blood coagulation.
The report, prepared by BioAgora, highlights the benefits of building-integrated greenery for biodiversity, climate resilience, energy efficiency, and human wellbeing. It offers actionable guidance for local authorities to integrate green roofs and walls into spatial planning and building codes.
A new policy brief from the University of Bonn and Vodafone Institute highlights Europe's hidden trade deficits with the US and China, which threaten its digital autonomy. The study advises strengthening manufacturing industry competitiveness and reducing dependence on China for digital goods.
Burst stimulation effectively mitigates decline in turning response decay, preserving stable frequency-response relationship and improving closed-loop locomotion control. The proposed navigation system achieves reliable path following with a success rate of 73% and average tracking error of approximately 12 mm.
Family physicians experiencing burnout are more likely to change practices or stop practicing entirely, with 43.5% reporting burnout in a recent study. This can lead to poorer patient outcomes, including increased ER visits and lower care satisfaction.
A global meta-analysis of animal activity found that wildlife shapes landscapes through everyday activities like burrowing and feeding. The study revealed a significant influence on geomorphic processes, with animal activity altering the porosity of soils and sediments by up to 136% in freshwater ecosystems.
The programme aims to nurture youth engagement in marine conservation and strengthen Hong Kong's environmental stewardship by providing hands-on training and empowering students as the next generation of ocean stewards. Students gain experience with advanced research techniques and build leadership and advocacy skills.
A sociologist's research focuses on personal stories behind assisted death decisions, challenging the assumption that choosing death is a rational decision. The study introduces concepts like biographical contraction and closure to understand the complex process of end-of-life choices.
A new study from the University of Oulu suggests that large swings in bedtime could double the risk of serious cardiac events. Inconsistent bedtimes were strongly associated with a higher risk of major cardiovascular events, especially among those who get less than eight hours of sleep.
A new study by UNSW Sydney and published in Carcinogenesis suggests that nicotine-based vapes are likely to cause cancers of the lung and oral cavity. The research, led by Adjunct Professor Bernard Stewart AM, analyzed global research and found consistent findings across multiple disciplines.
Researchers at the University of Bristol found that gentle human interactions trigger positive emotions in young chickens. The study's results suggest that early-life handling can shape animals' affective experiences and improve their welfare.
A study by IBEC reveals how thousands of amylin mutations influence its tendency to form toxic aggregates in the pancreas, linked to type 2 diabetes. The researchers created a mutational map using deep mutational scanning, identifying variations that promote or hinder amyloid formation.
The BD² Integrated Network Longitudinal Cohort Study combines clinical, biological, neuroimaging, and real-world behavioral data to transform understanding of bipolar disorder. The release includes data from 615 participants, covering mood, cognition, brain structure, wearable sensor data, and biological samples.
A new study from Boston University School of Medicine has discovered distinct blood metabolite patterns in centenarians that diverge from typical age trends. The findings suggest unique higher levels of certain primary and secondary bile acids and preserved levels of several steroids, linked to lower death risk. These metabolic signatu...
A new study found that parental academic pressure is linked to four distinct forms of motivational cost: effort, opportunity, psychological, and emotional. These costs are associated with school burnout and academic achievement, but not in the same way.
A team led by LMU physicist Dmitri Efetov has developed a new device capable of directly observing hidden electron interactions in graphene at room temperature. The quantum twisting microscope (QTM) enables continuous, dynamic control of the twist angle, bypassing traditional fabrication constraints.
Researchers discovered that inhibiting tick salivation prevents infection by targeting the tick's nervous system and salivary glands. The study found two distinct signalling pathways controlling saliva secretion, with acetylcholine playing a key role in stimulating salivation.
Researchers discover that azacitidine damages RNA, blocking protein synthesis and triggering the integrated stress response. Cells possess a tolerance to low levels of RNA damage, which determines the effectiveness of chemotherapy.
A recent study using sea slugs identified a cellular mechanism that strengthens long-term memory when exposed to new information at the same time each day. This discovery could provide insights into the most effective learning strategies.
Researchers at the University of Missouri have found that the Amazon molly's ability to reproduce asexually is due to gene conversion, which preserves and repairs DNA inherited from both parent species. This process allows the fish to maintain genetic health despite millennia of cloning.
Researchers discovered that soil bacteria can efficiently degrade toxic chemicals like styrene and phenol through alternative metabolic pathways. The study's findings have significant implications for environmental biotechnology and climate change mitigation.
Researchers developed STM-FPDT to overcome speed bottlenecks in conventional tomographic imaging. The technique enables parallel acquisition of multi-angle information, reducing acquisition time by 4.5-fold and enabling high spatiotemporal resolution observation.
A doctoral thesis confirms that polysaccharides extracted from algae can accelerate wound healing, reduce inflammation and protect skin cells. These natural compounds have potential as alternatives to synthetic treatments for chronic wounds, affecting millions worldwide.
The Gobi-HKU Fund I aims to invest in high-potential HKU spin-off startups, providing capital and strategic support. The fund will focus on AI, robotics, biotech, and other critical sectors, with investments already underway and more support on the horizon.
Children with tympanostomy tubes who swim in treated pools are not at increased risk of ear drainage. In contrast, exposure to untreated or natural bodies of water significantly increases the risk of developing recurrent otorrhea.
The program aims to improve the ability to predict, prevent and treat health complications in people living with Fontan circulation. Clinicians and researchers will generate scientific and clinical insights to develop tools guiding care for patients with Fontan circulation.
A recent study compares two devastating ice avalanches in the Indian Himalayas and Switzerland, revealing drastically different consequences despite similar physical characteristics. Climate change is destabilizing high mountain slopes due to glacier retreat, permafrost thaw, and extreme precipitation, making such hazards more frequent.
Researchers from the University of Tokyo have discovered a link between tropical volcanic eruptions and droughts in Asia. The study found that large eruptions can suppress monsoon convection, leading to reduced precipitation and droughts.
The study demonstrates simultaneous delayed fluorescence and phosphorescence in an organic luminescent material with multiple excited states. It reveals the existence of a second triplet state (T₂) and the competition between TADF and phosphorescence.
A new study uses optogenetics to control specific communication pathways in the common marmoset brain, offering a clearer view of complex behavior and brain disorders. This method enables researchers to manipulate individual long-range brain circuits with greater precision than before.
Scientists have discovered genetic pathways and compounds that protect cone photoreceptors, crucial for central vision, from degeneration associated with age-related macular degeneration. The study used human retinal organoids and identified two kinase inhibitors as key protective mechanisms.
A new study introduces CoPISA, a high-throughput proteomics workflow that uncovers how drug combinations reshape the soluble proteome. The research team applied CoPISA to two AML drug combinations, revealing conjunctional targeting and vulnerabilities in critical proteins.
Dr. Yangzhi Zhu has been awarded a prestigious Career Development Award from the American Heart Association to support his research in translational biosensing and organ health assessment. The award aims to develop innovative sensing strategies for improving donor organ condition and supporting better clinical care.
Researchers propose a terrain-aware framework for optimizing laser power-beaming networks in lunar permanently shadowed regions. The approach balances coverage, connectivity, and cost constraints to enable sustainable exploration tasks.
Researchers Paolo Sossi and Dan Bower found that the Earth is composed entirely of non-carbonaceous material, originating from the inner Solar System. This conclusion contradicts previous theories suggesting a significant contribution from the outer Solar System.
A new model of brain wiring could shorten the path to developing medicines for multiple sclerosis and other degenerative brain diseases. The model, made of a water-filled gel, replicates the physical properties of human axons and has been successfully grown from human cells in the laboratory.
Researchers discovered imported aromatic substances from Africa or Asia in Pompeii's incense burners, indicating a far-reaching trade network. The investigation also found evidence of grape products and native plants used in domestic cult practices.
A multicenter study found that red blood cell exchange transfusion significantly improves clinical outcomes for patients hospitalized with severe babesiosis, a potentially life-threatening tick-borne infection. The procedure was associated with substantially lower risk of in-hospital death or readmission.
Researchers at the University of Tartu have identified a new gene, MGRN1, linked to congenital heart malformations in fetuses. The study found that both parents carry a rare recessive variant of the gene, which causes developmental anomalies when inherited from both parents.
A research team at INRS has developed a simple and energy-efficient way to overcome the obstacle of detecting single photons in a sea of unwanted light. By repurposing a classical optical device, they succeeded in reorganizing light in time to highlight the useful photons without destructive amplification.
Researchers integrated topological photonics with nanoimprint lithography (NIL) to create a stable nanolaser. The work demonstrated type-III corner states and robustness against fabrication defects.
A recent article advocates for a risk-based approach to food safety, aiming to enhance sustainability and resilience of food systems. The authors argue that current policies leading to 'zero tolerance' are fueling the discard of safe food due to increasingly sensitive detection methods.
Researchers have discovered evidence of genetic material from high-risk bacterial groups in wastewater treatment plant effluent, highlighting the potential for antibiotic resistance to spread through ecosystems. This finding emphasizes the need for upgrading WWTPs with advanced technologies to protect public health and waterways.
The €30 million ASCEND project aims to accelerate catalyst discovery using Digital Catalysis and thin-film technologies. By combining AI with physical synthesis and stress testing, the project seeks to unlock performance breakthroughs for commercially viable large-scale deployment of green hydrogen and sustainable chemicals.
A study published in Cell Chemical Biology reveals that an impaired transport protein and ceramide buildup can trigger replicative senescence, a state where cells remain alive but no longer divide. Ceramides accumulate inside the endoplasmic reticulum, triggering stress signals that lead to cellular limbo.
Countries are taking different approaches to regulating polygenic embryo testing, which raises new ethical and legal concerns. The technology has expanded from screening for monogenic diseases to assessing complex traits like intelligence and disease risk, but its clinical value is uncertain due to environmental influences.
This study developed a new predictive model to assess chemical risks in cetaceans by considering the freely dissolved concentration of pollutants. The results show that mixed exposure to POPs at current environmental levels poses a low risk of reducing cell viability or inducing apoptosis.
A new microscopy method can distinguish lipid species in living cells using mid-infrared illumination and optoacoustic detection, producing a unique spectral fingerprint. This approach eliminates the need for chemical labels, reducing stress on cells and enabling real-time lipid mapping.
A longitudinal analysis of 42,000 participants found higher bone lead levels associated with significantly increased cardiovascular disease mortality risk. The study highlights the urgent need for strengthened surveillance, regulation, and remediation to reduce the lead-attributable burden worldwide.
A new study uses drone-based hyperspectral imaging to monitor changes in grassland ecosystems under different grazing pressures. The researchers found that biomass declines with increasing grazing intensity, while certain nutrient-related traits increase, suggesting a shift toward more stress-tolerant plant strategies.
A new study led by Krista Varady found that intermittent fasting reduces testosterone levels and improves female hormone levels in women with PCOS. The study tested time-restricted eating and calorie counting methods, showing that intermittent fasting had additional benefits over calorie counting.
The Joule Hive Thermal Battery system can generate and store heat up to 1,800 degrees Celsius using renewable energy sources like solar or wind. The system's thermal energy storage capabilities make it possible for industrial sites to rely on renewable energy sources flexibly.
A new study by researchers at the University of California, Davis found that breathing in common disinfectant chemicals known as QACs can be far more harmful than swallowing them. The study suggests higher health risks for respiratory diseases such as asthma and COPD from airborne exposure to disinfectant sprays and cleaning products.
Research finds that building gypsum powder reduces soil strength when exposed to water, but augments it at low concentrations of sodium sulfate. The study also reveals the impact of dry-wet cycles on soil pores, structure, and resistance.
A collaboration between Karolinska Institutet and Karolinska University Hospital has integrated whole genome sequencing into routine diagnostic investigations for rare diseases. This approach has enabled the diagnosis of a genetic cause in 23% of patients, with diagnoses involving variants in over 1,500 different genes.
Researchers identified NOX-1 as a key molecular target to prolong ketamine's therapeutic benefits. Combining ketamine with NOX-1 inhibitors significantly extended its antidepressant-like effects. K-4, a novel AMPAR modulator, also showed rapid antidepressant effects that persisted for at least 2 weeks.
Researchers found that early pregnancy probiotics containing Clostridium butyricum significantly reduced the recurrence rate of spontaneous preterm delivery, a major cause of neonatal illness and death. The study suggests that probiotic therapy may offer a simple strategy to prevent premature births in women at high risk.
A new framework proposes a Confucius-inspired approach to reimagining higher education, focusing on relational, contextualized, inward-calling, and unified practices. The study revisits foundational philosophy to address societal needs and challenges, highlighting the importance of self-cultivation and social order.
HeapGrasp uses RGB images to analyze object silhouettes and estimate its 3D shape, reducing the need for depth information. The approach achieves high accuracy while minimizing camera movement and execution time.
Researchers identify DNASE1L2 intron retention as a biomarker for TB progression and reveal its role in regulating inflammation. The study shows that upregulation of DNASE1L2-IR promotes host clearance of pathogen DNA, while downregulation weakens this antibacterial defense mechanism.