Researchers identify key mechanisms and molecular targets to prevent tumor progression in patients with rhabdomyosarcoma, a rare soft tissue cancer affecting young children. Two new treatment possibilities have been highlighted, targeting the IRE1α-XBP1 signaling axis and protein TAK1.
A University of Ottawa-led study has discovered a hidden network driving glioblastoma's aggressive growth, highlighting a promising target for next-generation therapies. The research reveals that a protein called OSMR plays a critical role in tumor progression and supports the survival of brain tumour stem cells.
A new study reveals that climate change will reshape the surface sunlight map, making polar regions dimmer and mid-latitude areas brighter. The redistribution of sunlight may impact energy balance, snow and ice processes, hydrological cycles, and solar energy resources.
A pilot study by Penn State researchers found that wearing a cooling cap for 30 minutes can improve a person's sense of well-being and reduce depressive symptoms. The study also showed an increase in alpha brain waves, indicating a calming effect.
Researchers identified a potential therapeutic lever against advanced bladder cancer, exploiting iron-dependent tumor cell death and its upstream regulatory mechanisms. The study found that JS-K can induce ferroptosis in bladder cancer cells by damaging mitochondria and disturbing iron balance.
A new study from Johns Hopkins Medicine found that an AI-assisted diagnostic tool increased referrals for African American patients with diabetes, resulting in more people receiving necessary eye exams. The study suggests that integrating such tools could help address healthcare disparities in underserved populations.
Researchers have sequenced and analyzed the two-toed sloth genome, discovering unique 'jumping genes' that are likely linked to their slow metabolism. These genes, which have been conserved over millions of years, may hold clues to understanding human health conditions such as diabetes, aging-related disorders, and muscle wasting.
A recent study by Marta Coll-Florit found that while Spanish newspapers are openly discussing suicide, they still employ stigmatizing metaphors such as 'war' and 'epidemic', which can perpetuate shame and guilt around the topic. The researcher argues that these metaphors convey a focus on individual blame rather than collective respons...
The Global Virus Network will host an international media briefing on the ongoing Ebola outbreak in the Democratic Republic of Congo. Frontline experts from the DRC, WHO, Africa CDC, and leading Ebola researchers will discuss outbreak response, diagnostics, vaccines, and therapeutics.
Dr. Kaiwen Hsiao's research focuses on developing a precise kind of 3D printing that uses light to build tiny structures out of polymer materials, addressing limitations in microelectronics manufacturing. The award will fund continued development of her platform, which holds promise for biomedical and battery applications.
By integrating GaN transistors into a diamond substrate, researchers have improved the speed and energy-efficiency of next-generation wireless devices. The diamond layer spreads and manages heat, allowing the transistors to operate at peak performance without degrading reliability.
A new study published in Menopause journal found that replacing animal protein with plant-based sources like soybeans, beans, and grains leads to significant weight loss in postmenopausal women. The study's lead author suggests that the quality of protein, not just quantity, plays a key role in weight regulation and metabolic health.
The application deadline has been extended to June 23, 2026, in two categories: Women's Health and Pharmaceutical Strategies and Innovation. The €45,000 prize fund includes six awards of €10,000, €7,500, and €5,000.
Dr. Josep Maria Ribera receives the EHA Clinical Excellence Award for his distinguished career in Acute Lymphoblastic Leukaemia treatment and patient care improvements. He is also recognized for his academic mentorship, training numerous haematologists who now lead positions in the field.
Researchers developed a layered sound speed gradient model to capture horizontal variations in the upper and deeper layers of the ocean. The new method significantly reduces positioning errors, achieving millimeter-level accuracy in simulations and field experiments.
A new computational tool predicts and avoids unwanted interactions in DNA origami, improving reliability for biomedical and technological applications. The tool optimizes DNA sequence choice to minimize off-target interactions, leading to more successful folding of nano-scale devices.
Cassie Duclos, a chemical engineering graduate student at Texas A&M University, has received the National Science Foundation (NSF) Graduate Research Fellowship. Her project focuses on redox-active polymers and dopants for improved battery performance, aligning with her passion for sustainable energy technologies.
The National Institute of Standards and Technology (NIST) has released an updated library of mass spectra, known as 'chemical fingerprints', for identifying unknown substances. The expanded library contains over 382,000 compounds, including 35,000 new additions.
The University of Texas at San Antonio Health Science Center has received a grant from the American Cancer Society to implement HPV self-collection in primary care settings. The pilot aims to make cervical cancer screening more accessible for patients who face barriers to traditional screening.
The University at Albany has received a $1.3 million award from the National Science Foundation (NSF) to establish an advanced wireless testbed, enabling researchers to develop next-generation technologies for wireless communications and sensing systems across a wide range of frequencies.
A team at TU Wien used a highly precise quartz crystal microbalance to study the impact of high-energy ion beams on surfaces. The results revealed that the measurement process not only affected the material under investigation but also the measuring instrument itself.
A new study found that a standardized five-step anesthesia protocol can safely induce dreaming during surgery, with most patients reporting pleasant and positive dreams. The study's findings suggest that anesthesia dreaming could support emotional well-being and improve patient satisfaction.
Motion sickness was a prevalent issue in 17th and 18th-century coach travel, with passengers experiencing discomfort due to crowded and unsanitary conditions. Historical research has found that the movement of coaches caused physical and psychological unease among travelers.
BIO-VITAL brings together leading scientists in aging biology to support industry partners evaluating novel gerotherapeutics. The program combines Einstein's decades of leadership in aging research with specialized research cores, proprietary models, and translational capabilities.
A new global early warning system predicts that over 3,500 species will face unprecedented heat between 2024 and 2025. The system identifies hotspots across Mexico, Sub-Saharan Africa, the Himalayan region, India, Pakistan, and Western Australia where exposure is both intense and extensive.
A new study in Geology has discovered evidence of a major impact event about 3.5 billion years ago on the Moon, matching the ages of known impacts on Earth and in the asteroid belt. The discovery provides a key link to the history of the inner solar system and sheds light on catastrophic events that may have affected early life on Earth.
The American Society for Nutrition (ASN) and The Obesity Society (TOS) have formed a strategic alliance to accelerate progress in both fields. This collaboration will drive evidence-based solutions that shape practice, inform policy, and improve health outcomes worldwide.
A new study found that social connections can help compensate for the loss of mentally stimulating interactions linked to work, with different types of relationships benefiting women and men. The researchers used data from 27 European countries and found that strong social networks appear to buffer the cognitive disadvantage of not wor...
Methanol-to-hydrocarbons reactions exhibit multiscale heterogeneity due to differences in molecular diffusion, crystal structure, particle composition, and reactor conditions. This nonuniformity affects catalyst performance and product selectivity.
Researchers at ISTA and Norwegian Institute of Public Health found that environmental factors influenced by parents' genes can significantly impact children's traits like height, body weight, and school performance. The study used genetic and phenotypic data from over 30,000 families to separate direct and indirect genetic effects.
Researchers studied the dietary strategies of savanna chimpanzees, revealing they use stick tools from eight plant species to extract aggressive army ants. The study suggests that eating these insects is a complex learning process for primates in harsh habitats.
A new study from the University of Illinois at Urbana-Champaign found that over 8 million people in the US, approximately 2.8% of the population, reported using psilocybin in the past year. Psilocybin users were more likely to be white, male, and affluent compared to nonusers, and often used other mind-altering substances.
A large-scale genetic study has identified 73 previously unknown genetic regions associated with the risk of lumbar spinal stenosis, as well as 15 known loci. The findings may help explain why some people develop symptomatic spinal stenosis while others remain unaffected.
A study by the University of Sharjah found that fear-based messaging in CDC anti-smoking campaigns can be highly effective when combined with credible information and practical guidance. The research identified five core strategies: fear-induced narratives, health-hazard emphasis, statistics, expert endorsement, and urgency.
Researchers are testing two treatments to help ranchers protect their herds from bovine theileriosis, a deadly disease spread by the invasive Asian longhorned tick. The treatments include a prescription anti-tick vaccine and a slow-release parasiticide, with initial results showing promise in reducing symptoms and mortality rates.
A study by the University of Helsinki found that the evolution of a single species can drastically change the composition of an entire microbial community. By analyzing the changes in bacterial genomes and species composition over four years, researchers discovered that one species' mutation led to a shift in the community's dynamics.
Researchers have successfully trapped a bismuth triangle between two metal complexes, forming the heaviest three-membered aromatic metal ring to date. This discovery has significant implications for the development of new functional materials, including intermetallic compounds and catalysts.
A research team from the Dalian Institute of Chemical Physics developed a free-standing ultrathin porous polymeric membrane that offers high selectivity and conductivity. The membrane was tested in a vanadium flow battery and achieved outstanding electrochemical performance, exceeding 80% energy efficiency.
Researchers developed a quantum sensing approach using superconducting qubits, combining non-equilibrium dynamics and quantum criticality to measure gradient field strengths with quantum-limit precision. The method avoids complex measurement setups, enabling highly precise estimates of gradient field strengths with limited samples.
Research reveals volcanic eruptions shape monsoon dynamics on centennial timescales, cooling the Northern Hemisphere and reducing cross-equatorial moisture transport. This process, combined with a mega-ENSO-like sea surface temperature anomaly pattern, decreases rainfall across Asian, North African, and North American monsoon regions.
Researchers analyzed permafrost samples to recover ancient environmental DNA, revealing genetic diversity among Arctic ground squirrels. The study uncovered previously unknown lineage dating back 700,000 years, challenging previous assumptions about fossil remains.
A new study maps music and chanting at football stadiums in various countries, showing significant differences in sound and purpose. In England, spontaneous collective singing drives stadium sound, while in Germany, organized and sustained rhythms dominate the atmosphere.
A study monitored the eggs of 14 bird species over a decade to characterize their exposure to environmental pollutants. The analysis detected contaminants derived from DDT and other pesticides, which impact species reproduction and ecosystem health.
Hospitalized children with acute respiratory tract infections often have underlying chronic conditions that require intensive care. The study found that these patients are at a higher risk of severe disease and death. Understanding the epidemiologic profile of this population can help optimize outcomes for pediatric patients.
Researchers analyzed over 264,000 pregnancies to confirm the safety of NSAIDs and paracetamol during pregnancy. The studies found no association between painkiller use and birth defects, dispelling long-standing myths.
Researchers developed a Pd-Ni5P4/DCEFS system that bridges the gap between sensitive sensing modules and high-performance therapeutic actuators. The closed-loop mechanism dynamically modulates hydrogen release based on endogenous NO concentration, creating an ideal microenvironment for macrophage polarization and wound healing.
The NEEDS 2026 Conference brought together scholars, practitioners, and policymakers to address complex challenges of interconnected global crises. Key findings include the importance of civil society as watchdogs and local communities being co-owners of transition projects. The DeCrises project emphasizes the need for a fundamental sh...
Damselflies break optical barriers to produce vivid, angle-independent colors using structural dispersion and pigment loading. This discovery provides a blueprint for creating sustainable, highly saturated photonic materials that could replace toxic synthetic pigments.
This study proposed a myoelectric prosthetic control framework that integrates tactile, kinesthetic, and EMG information to improve stability and adaptability during dynamic tool handling. The TKE-BGC system achieved stronger stability, accuracy, and generalization in dynamic tool handling.
Researchers found that long-term exposure to air pollution is associated with more advanced coronary artery disease, even at moderate levels. The study analyzed data from 11,128 adults and found that exposure to fine particulate matter and nitrogen dioxide increased the risk of coronary artery disease.
Ferroptosis spreading through propagative signals is a growing area of research, suggesting that cell death may propagate between cells and travel through tissues. Evidence points to lipid peroxides and iron as potential propagative factors, potentially contributing to the transmission of ferroptotic signals.
The partnership aims to enhance human flourishing and economic growth by translating the Metis brain economy vision into care that reaches patients inside health systems. West Health's work will focus on building integrated brain health delivery at scale, driving transformative change in healthcare.
Persons with diabetes are at higher risk of periodontitis, tooth loss, and peri-implantitis. Poor blood sugar control exacerbates these risks, highlighting the importance of close collaboration between healthcare and dental care providers.
The Xi Peng laboratory has developed LargePNet, a novel general-purpose fluorescence image restoration network that aggregates large-view structural information to overcome the loss of global contextual information caused by conventional patch-based training. This results in improved restoration accuracy and large-size image inference ...
The JTMF Foundation has expanded its footprint with a $3.3 million gift to fund three main initiatives: identifying early signs of Alzheimer's in adults with Down syndrome, expanding access to cutting-edge clinical research, and developing best-practice guidelines.
Researchers identified a promising new strategy for reversing autism-related brain deficits by targeting a specific glycine transporter. The therapy restored NMDA receptor function in mouse models and human brain organoids, improving behavioral abnormalities such as social interaction and repetitive behaviors.
Oxygen isotopes in forsterite affect Raman spectroscopy results by causing frequency shifts, lower symmetry, and peak splitting, leading to broader peaks. The study provides a theoretical framework for better interpretation of spectra data.
Researchers at Memorial Sloan Kettering Cancer Center found that the tail region of mRNAs helps fold thousands of critical regulatory proteins correctly. This discovery sheds new light on fundamental biology and has practical implications for laboratory research.
A new deep learning framework uses diffusion tensor imaging to identify subcortical vascular cognitive impairment (SVCI) with high accuracy. The model stratifies patients into low-, moderate-, and high-risk subgroups for each cognitive domain, offering a more objective and scalable tool for clinicians.
A new study by Tampere University researchers found that maternal pre-pregnancy hypertension and child body composition may contribute to the development of fatty liver disease. The study also identified dietary factors, such as high protein intake and low fruit consumption, as risk factors for elevated liver enzyme levels in children.