Researchers have discovered a novel approach to ease chronic and acute pain caused by sickle cell disease, using cannibinoids that equally lessen pain in animals as opioids, but with much smaller doses. The treatment has great promise for patients with this genetic blood disorder.
Agricultural Research Service chemist Thomas Wang found that resveratrol, a bioactive compound in grapes and plant foods, can inhibit cancer cell growth but also increase tumor vessel development with prolonged exposure. The study suggests that diet complexity and gene expression are key layers in cancer development.
Researchers found that social interaction and a richer living environment significantly reduced tumor mass and volume in mice with cancer. The study suggests that low-stress, mentally stimulating environments may be beneficial for cancer treatment.
Researchers found diverse marine life on the Mid-Atlantic Ridge, including a missing evolutionary link between backboned and invertebrate animals. The team discovered three new species with different colors and shapes, as well as sea cucumbers with unique swimming abilities.
Researchers discovered that plants integrate information about food location and competitors to develop unique root growth strategies. This complexity is a level of sophistication previously thought exclusive to animals.
A study of banded mongooses in Uganda found that these animals pass on traditions from one generation to the next, a practice previously thought to be reserved for humans and intelligent animals. This discovery has significant implications for understanding how complex cultures can develop.
A Tufts University study sheds light on how marine animals like Galapagos iguanas survive stress, revealing the crucial role of negative feedback in coping with 'fight or flight' responses. The research also has implications for understanding wildlife responses to environmental disasters and oil spills.
Researchers collecting mollusk specimens from the Gulf Coast will analyze growth rings in shells to determine how quickly harmful compounds from the oil become incorporated into the animals' bodies. They will also test for hydrocarbons in tissues and measure changes in growth rate and survivorship.
A new study challenges the long-held assumption that children adopt an anthropocentric perspective on human-animal relationships from birth. Instead, research suggests that human-centered reasoning emerges around age 3 in urban children, reflecting their community's perspectives.
Researchers discovered an identical gene for antibiotic resistance in human and animal samples, suggesting its transfer between bacteria species. This finding poses a risk to the treatment of common human infections like UTIs, which are increasingly difficult to treat due to rising antibiotic resistance.
Researchers have found that parvoviruses can completely regress malignant brain tumors in rats and human gliomas. The viruses target cancer cells without affecting healthy tissue, making them a potential new approach to treating glioblastoma.
Researchers discovered that aphids can produce carotenoids, essential nutrients crucial for vision, skin health, and bone growth. The yellowish-green aphid strain produced carotenoids by acquiring a fungal gene through lateral transfer, challenging conventional wisdom on animal nutrient production.
The Field Museum and University of Chicago launched the Emerging Pathogens Project to study emerging diseases in animals, such as bird flu, malaria, and AIDS. By analyzing DNA data from collected specimens, scientists aim to understand how diseases evolve and spread between animal species.
A Princeton University-led team tracked fever and sickness behaviors in song sparrows using radio transmitters, discovering that different populations respond differently to infection. The study's findings may aid in forecasting where diseases will take hold, including West Nile virus.
A study published in the Proceedings of the National Academy of Sciences found that insect-gobbling animals increase plant growth by reducing plant-feeding insects' damage. The research solidifies birds, bats, lizards, and other similar animals' importance to ecosystem health.
Researchers have discovered small animals in the Mediterranean Sea that live their entire lives without oxygen and reproduce despite a complete absence of oxygen. These multicellular organisms possess organelles resembling hydrogenosomes found in anaerobic environments, challenging our current understanding of life on Earth.
Researchers have discovered a key ingredient in animal color patterns: a diffusible protein called Wingless. This morphogen prompts cells to make pigment, creating intricate designs like stripes and spots. The study's findings have implications for understanding how animals evolve their color patterns.
A new study reveals that deep-sea scavengers outcompete smaller animals for food in ocean canyons, leading to reduced biodiversity. Larger animals sense the presence of food and converge on the canyon floor, devouring all available nutrients and leaving little for other animals.
Researchers at UC Berkeley found that dominant hyenas produce steady, confident-sounding giggles, while subordinate ones have more variable calls. The study's findings suggest that the frequency analysis of these calls can reveal an animal's social stature and age.
Researchers found that domestic guinea pigs excelled in a water maze test due to their improved ability to decipher guidance symbols, while wild cavies were stronger swimmers. The study suggests an adaptation in domesticated animals for efficient problem-solving in human-made environments.
Researchers at Stanford University have made major advances in the optogenetics technique, enabling a wider range of experiments with larger animals. The new capabilities include using any visible color of light and harnessing intracellular trafficking to spread the optogenetic effect throughout brain circuits.
A recent study found that dolphin tourism in Zanzibar is causing stress and exhaustion among bottlenose dolphins. The research highlights the need for regulation of the industry to minimize long-term negative impacts on the animals and their habitats.
A study published in the Journal of Cerebral Blood Flow & Metabolism found that repeated anesthesia can cause a significant decrease in stem cells in the hippocampus, leading to impaired memory and learning in young animals. The researchers believe this effect may be age-related, with younger animals being more susceptible.
Recent biologging studies reveal surprising behaviors, such as Atlantic bluefin tuna's 5,000-foot dives and elephant seals' annual 40,000-mile migrations. The research also provides insights into ocean animals' physiological parameters, environmental preferences and conservation status.
Researchers at the University of Edinburgh found that the hormone vasopressin plays a crucial role in helping animals recognize others through scent. This ability is essential for establishing strong bonds with other animals, and its failure may contribute to conditions like autism and social phobia.
Scientists at UH found that better food from high-latitude plants may explain why animals grow bigger in cold climates. The study suggests considering ecological interactions beyond traditional physiological responses to temperature.
Research by Tel Aviv University's Prof. Yoram Yom-Tov reveals that animals at higher latitudes are adapting to rising temperatures by altering their diets and body sizes. This adaptation is seen in birds getting smaller and mammals getting bigger, allowing them to cope with warmer temperatures.
Researchers create photoswitch composed of dithienylethene, which paralyzes C. elegans worms with ultraviolet light and reverses paralysis with visible light
Scientists found conserved microRNAs in animals as diverse as sea anemones, worms, and humans, suggesting an early origin of these tissues in animal evolution. The discovery opens new avenues for studying the current functions of specific microRNAs.
A study confirms the long-standing idea that animals such as lemurs and flying foxes arrived in Madagascar via natural rafts blown out to sea. The research, published in Nature, uses a three-year computer simulation of ancient ocean currents to support the theory, which was previously introduced by George Gaylord Simpson.
Researchers found that expressing mutant DISC1 during prenatal periods, postnatal periods, or both led to distinct brain alterations and behaviors resembling schizophrenia or mood disorders. The study suggests that manipulating DISC1 expression timing may help develop new therapies for psychiatric disorders.
Researchers have identified a leptin-controlled gene that can reverse diabetes in animals and may have similar therapeutic effects in humans. The study found that low levels of leptin can correct insulin resistance and diabetes without causing significant weight loss.
North Carolina State University's College of Veterinary Medicine requires all students to receive disaster training, enabling them to respond to the needs of both people and animals in the wake of disasters. This comprehensive program equips veterinarians with advanced state and federal disaster certifications.
Researchers estimate that swimming animals generate extensive 'biogenic' mixing in the ocean, which may impact climate models. The effect is primarily due to animal displacement, not turbulence, and affects even deep-sea creatures.
A study led by University of Wisconsin-Madison researchers reveals that the decline of iconic ice age animals like mammoths and mastodons preceded a dramatic shift in North America's plant communities, fueled by wildfires. The research sheds light on the dynamics of extinction and its impact on landscapes.
Researchers create photoswitch that triggers and reverses paralysis in C. elegans worms using ultraviolet and visible light. The study demonstrates the potential of such 'photoswitches' in medicine and research applications.
Scientists at Queen Mary University of London found that insect brains are capable of intelligent behaviors like counting and categorizing, challenging the idea that larger brains are more intelligent. Research suggests that many size differences in brain size only exist in specific regions and may not lead to increased complexity.
A study suggests that many dinosaurs were probably endothermic, athletic animals due to their high energy requirements during walking and running. This trait may have enabled them to thrive in various habitats, including colder regions, allowing them to cover the entire Mesozoic landscape.
Research suggests that many dinosaur species were probably endothermic, with the potential for athletic abilities rivalling those of present-day birds and mammals. This would have allowed them to inhabit colder habitats, but also required a constant supply of fuel due to rapid metabolisms.
Researchers at the University of Edinburgh discovered a strain of Staphylococcus aureus bacteria jumping from humans to chickens, marking the first clear evidence of bacterial pathogens crossing from humans to animals since domestication. This finding has significant implications for poultry farming and food security.
A Spanish researcher analyzed wolf feces and found that 62.8% of prey was roe deer, while domestic sheep and goats only made up 7.7% and 2.9%, respectively. The study suggests that wolves do not prioritize easily available prey like domestic animals.
Researchers have discovered a new species of shell-covered animal from the Early Cambrian epoch, dating back around 520 million years. The fossils indicate that these early animals were larger than previously thought and provide valuable information on their evolution and relationships to other species.
Researchers at Georgetown University Medical Center found that a tailored approach to physical therapy can restore a wider variety of functions in rats with spinal cord injuries. After four weeks of training on a robotic device, trained animals had shorter stride lengths and improved walking performance compared to non-trained animals.
An international research team has discovered a common genetic program for programmed cell death in plants and animals, which is evolutionarily related and functions similarly. This finding highlights the importance of comparative studies across different species to understand fundamental cellular mechanisms.
A recent study by Ohio State University found that microchipped animals were reunited with their owners in almost three out of four cases. The return-to-owner rate for cats was 20 times higher and for dogs 2 1/2 times higher than for all stray cats and dogs, highlighting the effectiveness of microchip technology in pet reunification.
A state-of-the-art surveillance system will be developed to monitor emerging and re-emerging infections in wildlife, assessing risks to domestic animals and humans. The project aims to predict and manage disease threats from wildlife, using cutting-edge molecular technologies.
Australian researchers have discovered a vast number of new species of invertebrates living in underground water, caves and micro-caverns across arid and semi-arid Australia. The team found whole communities of previously unknown invertebrate animals, revealing a completely new component to the country's biodiversity.
A research team has found the first evolutionary branching for bilateral animals, resolving a long-standing debate about a group of ancient flatworms called Acoelomorpha. The study reveals that Acoelomorpha is a sister clade to other bilateral animals, providing key insights into the most recent common ancestor.
New research suggests that some nonhuman animals, including dolphins and macaque monkeys, may possess functional parallels to humans' consciousness and cognitive self-awareness. These species exhibit behaviors such as hesitation and uncertainty, indicating a capacity for metacognition.
Analysis of ancient rock isotopes reveals a rise in atmospheric oxygen 580 million years ago triggered the evolution of large complex animals. This discovery confirms oxygenation of oceans as a driving force for animal life.
Dr. Paul Flecknell, a renowned expert in laboratory animal pain management, has been recognized with the 2009 Charles River Laboratories' Excellence in Refinement Award. His work focuses on developing methods of pain assessment and alleviation for various species.
Researchers at MIT's Picower Institute for Learning and Memory found that rats use a mental instant replay of their actions to help them decide what to do next. The study reveals that these sequences also occur when the animals are awake and may help them consider future options.
A new study by Johns Hopkins Bloomberg School of Public Health estimates that European REACH legislation for chemicals may require up to 54 million research animals and $13.4 billion over the next 10 years.
A new analysis by Jerome Siegel reveals that sleep's primary function is to regulate behavior and increase efficiency, rather than solely for brain maintenance or longevity. Sleep duration varies across species based on factors such as eating needs, migration requirements, and predator avoidance.
Researchers from Caltech have discovered a mechanism that explains how tiny swimming animals can affect the ocean environment, creating instability and mixing large scales. The impact of biogenic ocean mixing is estimated to be comparable to wind forcing and tidal forcing.
A new monitoring system developed by Johns Hopkins researchers allows for the non-invasive pinpointing of Mycobacterium tuberculosis in mouse lungs, speeding up preclinical testing of TB drugs and vaccines. This innovation enables fewer animals to be used, reducing the need for lengthy and complicated regimens.
A new study suggests that a 700-mile US-Mexico border wall could significantly alter wildlife movement and connectivity, threatening populations of some species. Design tweaks and technology can improve animal movement, but the impact on biodiversity is still uncertain.
A new study by George Mason University researchers challenges the long-held notion that dinosaurs were massive creatures. They found that using a flawed statistical model led to overestimations of dinosaur weight, revealing some species may have been smaller than initially thought.
Researchers found that prairie dogs prefer plants with low levels of selenium, suggesting that high levels act as a deterrent. This suggests that plants may use metal hyperaccumulation to defend against herbivores, including prairie dogs.
The National Resource for Aplysia, a world-leading facility for sea slug research, has secured a $2.7 million NIH grant renewal for five years. The facility will provide scientists with abundant Aplysia californica animals to study basic mechanisms of memory and learning.