Researchers have discovered molecular basis of hereditary Alzheimer's disease, revealing a crucial role in the cleavage process of APP protein. Stabilizing Gamma Secretase-APP interaction may prevent release of toxic amyloid beta fragments, delaying or preventing the disease.
A team of astronomers detected a massive star's titanic explosion and measured its development and decay in unprecedented detail. The findings provide strong evidence for one of two competing models for how gamma-ray bursts produce their energy, with the data showing powerful magnetic fields confining and directing the radiation.
A team led by University of Maryland astronomers has constructed one of the most detailed descriptions of a gamma-ray burst to date, shedding light on the initial 'prompt' phase and the evolution of large jets of matter and energy. The data suggest that both magnetic fields and matter play key roles in shaping the jets.
A combined analysis of NASA's Fermi Gamma-ray Space Telescope and H.E.S.S. data suggests the galactic center contains a high-energy trap that concentrates cosmic rays, mostly protons. This results in a gamma-ray glow extending to the highest energies observed.
Researchers have discovered that corticosteroids, a main treatment for asthma, can actually exacerbate the disease in certain cases. The study found that high levels of inflammatory protein CXCL10 and interferon-gamma are linked to poor lung function and worsening symptoms.
Researchers at Waseda University developed the world's first compact Compton camera for medical imaging, capturing high-resolution 3D molecular images of a live mouse in just 2 hours. The device weighs only 580g and can image energy from hundreds to mega-electron volts.
The study found that low-intensity gamma radiation is only destructive and has a linear correlation in dose-effect coordinates. The duration of exposure is more significant than the absorbed dose in terms of toxic effect on organisms.
Scientists have observed a surprising competition between electromagnetic and neutron decay modes in a tin-133 nucleus. The discovery suggests that nuclear structure effects play a more significant role than previously thought, potentially altering our understanding of nuclear synthesis and the creation of heavy elements.
Scientists analyzed dozens of TGFs launched by tropical storms, confirming that storm intensity alone is not the key factor for producing these events. Most TGFs occurred as systems intensified, with stronger electric fields driving clouds higher into the atmosphere.
Astronomers discover enigmatic flash of X-rays from galaxy 10.7 billion light years away, exhibiting properties unlike known gamma-ray bursts or stellar destruction; scientists struggle to understand its origin and potential implications for compact star mergers.
Researchers develop a tiny X-ray sensor integrated onto an optical fiber, enabling high-precision medical imaging and therapeutic applications. The sensor has a spatial resolution of around 1 micron, allowing for real-time measurement of radiation delivery to tumors via endoscopy.
Researchers at Kyoto University have developed a novel imaging technique using gamma-ray spectroscopy to visualize and quantify ground-level radiation. This method enables the detection of previously unknown contamination hotspots around the Fukushima Daiichi Nuclear Power Plant, allowing for more effective decontamination efforts.
A new study identifies Gamma Delta T cells as adaptable immune cells with immunological memory against previous infections and cancerous targets. This finding challenges traditional views of these cells as 'natural born killers' and presents opportunities for developing new cell therapies and vaccines.
A team of scientists from Clemson University has discovered five ancient galaxies with extremely powerful supermassive black holes, emitting billions of times more energetic gamma rays than visible light. The oldest known gamma-ray blazars were previously thought to be over 2 billion years old.
The study focuses on combining SPRA technology with polypseudorotaxane (PPRX) technology to create a sustained and controllable insulin release system. Four types of PPRXs were developed, showing improved blood glucose reduction times and safety profiles.
Fermi data reveals concentrated gamma rays at Andromeda's center, sparking speculation about dark matter. The unusual distribution may be caused by unknown sources or the presence of dark matter.
Astronomers discover five new gamma-ray blazars with massive black holes, challenging current ideas on their formation and growth. The discoveries suggest that these objects could have formed rapidly in the universe's early history.
The Fermi telescope has observed high-energy light from solar eruptions on the far side of the sun, which should block direct light. This allows scientists to study how charged particles are accelerated to nearly the speed of light during solar flares.
Researchers found that tree shrews have a natural immunity to HBV, with cytokine interferon-gamma playing a key role in the activation of hepatic natural killer cells. The study also revealed the importance of extracellular vesicles in regulating innate immune responses to HBV infection.
Fast radio bursts (FRBs) emit non-radio emission, challenging models and suggesting severe consequences for host galaxies. The discovery of FRB 131104's gamma-ray counterpart opens possibilities for detecting long-lived counterparts using X-ray, optical, and radio telescopes.
Researchers at General Atomics have developed a gamma ray camera to image energetic electrons in ultra-hot fusion plasma, providing unprecedented insights into their behavior. The device reveals that radiation forces can sap high-energy electrons, while collisions with other electrons are more effective at lower energies.
Researchers measured gamma radiation emitted by common household items in a North Carolina home, revealing surprising levels of radiation from everyday objects. The study aims to help people understand news stories about radiation and prevent panic by placing radiation readings into perspective.
A recent study published in Cell found that gamma delta T cells prevent tumor-fighting immune cells from attacking pancreatic tumors. This infighting makes immunotherapy less effective, with only 8% of people surviving five years after diagnosis.
The Fermi mission has excluded a small range of axion-like particles that could have comprised about 4 percent of dark matter, while also providing the strongest constraints to date for certain masses. Additionally, researchers found no statistically significant signal from dark matter annihilation in the Small Magellanic Cloud.
New data from NuSTAR reveals large numbers of black holes sending out high-energy X-rays, helping astronomers understand growth patterns and evolution of supermassive black holes. The study resolves 35% of the high-energy X-ray background, uncovering details about the most obscured black holes hidden in gas and dust.
Researchers discovered a UV-B receptor that activates proteins to build defense mechanisms, allowing plants to tolerate harmful UV-B rays. Plants also use UV-B rays to influence growth and development, making them essential for survival.
Researchers have successfully created a controlled beam of ultra-energized photons, or gamma rays, from a laser using simulations on the Lonestar and Stampede supercomputers. The breakthrough has potential applications in fields such as cancer treatment, cargo screening, and fundamental science studies.
A new study shows that post-transplant gamma-ray irradiation can prevent immature cells from forming tumors in rat brains after human iPS cell transplantation. This approach aims to improve the safety of cell replacement therapy using human iPS cells for Parkinson's disease treatment.
A new study by the Scripps Institution of Oceanography has challenged the assumption that oceanic manta rays are long-distance travelers. The research team found that these massive creatures tend to stay close to their local habitats, suggesting a high degree of residency behavior.
The novel portable diagnostic tool offers a multi-dimensional look at the body by combining optical and gamma imaging, allowing physicians to visualize molecular data alongside surface organ images. Clinical pilot studies have shown promising results in imaging lymphatic and thyroid tissue, as well as tear ducts.
Researchers from Scripps Research Institute have been awarded $1.3 million to optimize probes for a new cancer treatment approach. The study focuses on the retinoic acid receptor-related orphan receptors (ROR) gamma and molecules that bind to it, aiming to trigger immune cells to attack tumor cells.
Researchers detected gamma-ray emission in Arp 220, revealing extreme energetic processes and hidden cosmic rays. The finding expands energy observations of galaxies and sheds light on the population of extreme energetic particles.
A study published in PLOS ONE found that gamma-retroviruses preferentially insert near cancer-associated genes, suggesting a new tool for identifying genes driving specific cancers. This discovery could lead to the identification of potential therapeutic targets.
Research at Gladstone Institutes found that the apoE4 protein disrupts brain activity in mice, impairing memory replay and consolidation. The study suggests that disrupted slow gamma activity during ripples is a major consequence of apoE4 expression, likely leading to impaired memory loss.
A Louisiana State University student-led team has been awarded a $200,000 grant to develop an instrument that will fly into a thunderstorm to measure how lightning produces high-energy gamma-rays. The project, called Correlation of Terrestrial gamma flashes, Electric fields and Lightning strikes, aims to study the electrical and radiat...
A rare type of iron nucleus, with a half-life of 2.6 million years, serves as a 'clock' to measure the distance between Earth and the source of galactic cosmic rays. The data suggest that nearby supernovae in massive star clusters are responsible for creating these nuclei.
The study uses a rare type of cosmic ray that acts like a tiny timer to determine the age and distance of galactic cosmic rays. The results suggest that these cosmic rays were created recently and are coming from nearby clusters of massive stars within 3,000 light years of Earth.
The detection of a brief gamma-ray burst consistent with the same part of the sky as gravitational waves offers a unique window into the universe. By analyzing this event, scientists can gain insights into the dynamics leading up to black hole mergers and shed light on the nature of gravity.
The HAWC Gamma-ray Observatory has released a new survey of the sky made from the highest energy gamma rays ever observed, revealing new high-energy sources within our own Milky Way galaxy. The observatory has also provided more detail on known sources, offering a deeper understanding of high-energy processes taking place in our galaxy...
Researchers at Penn State College of Medicine have discovered a potential target for treating lupus: interferon gamma. The cytokine stimulates immune cells and is involved in the formation of autoreactive B cells that produce autoantibodies, leading to inflammation and tissue damage.
Researchers discover a new way to view complex groups of atoms in motion using coherent X-rays, revealing voids and nanocolumns that form during thin film production. This technique improves the quality of commercial applications such as solar panels and drug delivery systems.
Researchers have developed location-specific standards for identifying human remains based on X-rays of the spine, upper leg, or skull. These standards provide a consistent approach to identification with high accuracy and reduced misclassification rates. The study's findings have significant implications for forensic experts and can h...
A team of researchers has found evidence for a particle accelerator in the center of the Milky Way that can accelerate protons to petaelectronvolt energies. The discovery sheds new light on the origin of galactic cosmic rays and challenges existing theories.
A new study found that treatment using Gamma Knife radiosurgery is often safer than leaving untreated AVMs, particularly for patients with a high life expectancy. The research suggests that younger patients are more likely to benefit from treatment, with a 10-year life expectancy of 50 years or more.
Researchers at Sidney Kimmel Cancer Center found that Gamma Knife and RapidArc radiation therapy for brain metastases produce similar results, with the latter being faster. This study offers patients a choice of treatments and highlights the importance of advanced radiosurgery technology in treating increasing cases of brain metastases.
Researchers suggest that twin black holes detected by LIGO might have formed inside a single, massive star. The star's death generated a gamma-ray burst, which was observed by the Fermi Space Telescope.
Researchers found intriguing contradictions between IceCube neutrino data and Fermi gamma-ray data, suggesting 'hidden accelerator' origins of high-energy cosmic neutrinos. Proton-photon interactions may block high-energy gamma rays from escaping, enabling the use of neutrinos as new probes of dense astrophysical environments.
Astronomer Maxim Pshirkov discovered a new source of gamma-radiation in the Gamma Velorum binary system, confirming that colliding stellar winds generate high-energy photon emission. The system's strong stellar winds produce a photon flux with energies exceeding 100 MeV, detected by Fermi LAT.
ASTRO-H will observe X-ray sources like galaxy clusters and neutron stars up to 10 times fainter than its predecessor Suzaku. The observatory uses four co-aligned focusing X-ray telescopes and cutting-edge instruments to provide simultaneous coverage across its entire energy range.
Researchers propose using twisted X-rays to study non-crystalline but symmetric structures like helices. This method matches the symmetry of incoming radiation to the structure's symmetry, producing sharp peaks in diffraction data that can be used for accurate structure prediction.
Two studies find gamma ray signals in the galactic center are unlikely caused by dark matter collisions. Instead, they could be attributed to fast-rotating stars called millisecond pulsars. Researchers used statistical analysis methods to analyze images of gamma rays captured by NASA's Fermi Gamma-ray Space Telescope.
CNIC researchers have identified a new target for the treatment of fatty liver disease, p38 gamma and p38 delta proteins. Inhibition of these proteins with specific inhibitors has shown potential as a treatment for fatty liver disease, potentially preventing inflammation, liver damage, and diabetes linked to obesity.
The GRIPS balloon mission observes extremely high-energy radiation released by solar flares, pinpointing precise times and locations of gamma ray emission. The team's instrument sees this emission three times more sharply than any previous instrument.
The Fermi team has created the most detailed census of the sky yet made at extreme energies using improved data processing methods. The new sky map reveals hundreds of high-energy sources, including blazars and remnants of supernova explosions.
A Kyoto-led team reports that black hole activity can be observed through visible light during outbursts, and that optical rays provide reliable data for black hole activity. The study used a 20 cm telescope to observe V404 Cygni, detecting repetitive patterns with timescales of several minutes to a few hours.
Astronomers measured the density of photon fog between Earth and quasar PKS 1441+25 using high-energy gamma rays. The data validated theoretical models for the number and brightness of stars and galaxies in the universe going back 7.6 billion years.
Researchers detected gamma rays from a rare blazar galaxy, PKS 1441+25, 7.6 billion light-years away, setting new bounds on the extragalactic background light. The observations provide clues to the production of high-energy gamma rays and their interaction with the surrounding environment.
The VERITAS telescope detected powerful gamma rays from a distant galaxy, PKS 1441+25, revealing details about the black hole engine at its center. The gamma-ray emission was found to be located within the relativistic jet, but surprisingly far from the black hole, and is estimated to be around 5 light-years away.
Astronomers observed gamma rays from PKS 1441+25, a blazar galaxy 7 billion years away. The high-energy light revealed a single region far from the power source, contradicting previous assumptions.
A supercomputer simulation demonstrates that a collapsing massive star can generate enormous magnetic fields, focusing gas along the rotation axis to create jets producing oppositely directed blasts of highly energetic gamma rays. This breakthrough model sheds light on the process behind hypernovae and gamma-ray bursts.