Researchers suggest a long-term memory test combined with a brain scan can detect early Alzheimer's disease. Long-term memory tests reveal deficits in the brain's ability to remember, which may be reversed by new treatments.
A new study using optogenetics has increased long-term memory in mice with fear disorders, such as phobias and post-traumatic stress disorder. The technique, tested in two mouse populations, improved memory recall and reduced fear responses, offering potential therapeutic targets for these conditions.
A new study by SUNY Downstate resolves the controversy over PKMzeta's importance in forming and retaining memories. Mice lacking PKMzeta recruit a closely related molecule, PKCiota/lambda, to compensate for its absence, highlighting the brain's memory system durability.
A team of scientists has identified a back-up mechanism for memory storage that takes over when the molecular mechanism of primary long-term memory storage fails. They found that mice engineered without an enzyme crucial to long-term memory storage still form memories because they deploy an alternative method, involving PKCλ/ι.
Research at Gladstone Institutes found that the apoE4 protein disrupts brain activity in mice, impairing memory replay and consolidation. The study suggests that disrupted slow gamma activity during ripples is a major consequence of apoE4 expression, likely leading to impaired memory loss.
A new study suggests that cognitive-behavioral therapy can help prevent long-term memory issues caused by chemotherapy. The therapy, called Memory and Attention Adaptation Training (MAAT), was developed to increase awareness of situations where memory problems arise and develop skills to compensate for memory dysfunction.
Scientists have identified a unique memory suppressor gene in Drosophila that could hold the key to developing new Alzheimer's treatments. The gene, known as DmSLC22A, is involved in filtering information and storing important parts when the brain prioritizes memories.
Researchers have successfully grown ultra-thin ferroelectric films based on hafnium oxide, which could potentially be used to develop non-volatile memory elements. The films' ferroelectric properties are compatible with silicon technology, paving the way for the creation of new non-volatile memory devices.
A new study has identified a pattern of brain activity linked to memory problems in people with schizophrenia. The findings provide evidence that the dorsolateral prefrontal cortex is compromised in patients with schizophrenia and may be a specific target for treatment.
Researchers found that neurons fire in brief, coordinated bursts as information is held in working memory, allowing for multiple items to be stored separately. This discovery fits a new model of rapid synaptic strength changes and gamma frequency oscillations.
A new study found that HIV-infected individuals have impaired affinity maturation of memory B cells, resulting in low frequencies of somatic hypermutation and poor HIV-neutralizing capacity. This immune dysfunction contributes to the ineffective antibody response against HIV.
Researchers used optogenetics to re-grow lost spines and restore memories in AD mice by stimulating engram cells. This method suggests that impaired retrieval of memories underlies early Alzheimer's disease symptoms and highlights the importance of targeted manipulation of neurons for future therapies.
A study published by the American Academy of Neurology found that women tend to perform better on verbal memory tests and have less brain shrinkage in areas responsible for verbal memory. This suggests that women may be protected from loss of verbal memory skills before Alzheimer's disease symptoms appear.
Researchers found an association between high BMI and poorer performance on a test of episodic memory in young adults. The study suggests that obesity may be linked to changes in brain structure and function, potentially affecting memory and decision-making abilities.
A new study by Simon Fraser University researchers found that differences in working memory capacity correlate with the brain's ability to actively ignore distraction. Individuals with low memory capacity are unable to suppress distractors, leading to attentional deficits.
The brain regulates the size of neuronal ensembles that reflect the memory trace to optimize performance, researchers from Université de Genève demonstrate. The study shows that inhibiting or resurfacing a memory can be achieved by targeting neurons in the hippocampus.
Researchers at Scripps Florida identified a memory suppressor microRNA called miR-980, which regulates neuronal excitability and inhibiting it improves memory. The study found links between miR-980 and autism spectrum disorder, suggesting that the microRNA may contribute to the development of the condition.
Cognitive neuroscientist Rosie Cowell is using a five-year grant to develop and test a theory of memory interaction with fine-grained visual perception. She will use computational modeling and memory experiments to investigate how the medial temporal lobe affects both memory and visual perception.
Researchers have developed an entirely new form of digital memory using antiferromagnets, which can be controlled with electrical pulses. This technology has the potential to increase storage density, reduce energy consumption and improve speed.
A new IU study confirms the existence of independent working memory systems in animals, which could inform new pre-clinical research models for Alzheimer's disease treatment. The results show that rats possess two separate memory resources, allowing them to recall more information across multiple categories.
A study by Baycrest Centre for Geriatric Care reveals that brain connectivity patterns differ between individuals who remember episodic details versus facts, suggesting a lifelong 'memory trait'. This finding may have implications for understanding aging and brain health.
Studies investigate biological factors behind memory decline in people with epilepsy, particularly those with temporal lobe epilepsy. Loss of neurons from the hippocampus is a common cause of impaired memory. Researchers also explore effects of seizures on signaling pathways and brain activity.
Researchers found that aerobic exercise improves the volume of the entorhinal cortex, an area crucial for memory, in healthy young adults. This study suggests that regular physical activity may be beneficial for brain health and cognitive function in younger generations.
A new study has found that older adults who take more steps perform better on memory tasks than those who are more sedentary. The association between physical activity and memory was strongest with a task requiring recalling face-name associations.
Researchers found that consuming sweets activates neurons in the dorsal hippocampus, a critical region for episodic memory. This process is necessary for making memories, including those related to eating behavior. The study suggests that forming memories of meals can help control eating habits.
A study of 1,107 dementia-free women found that those who complained of memory problems were 70% more likely to develop a diagnosis compared to those without complaints. Women with complaints were also 3-9 times more likely to develop a diagnosis at different time points.
A one-month training program on the Virtual Week computer brain game strengthens prospective memory in older adults, which is crucial for planning and everyday functioning. The study shows that these cognitive gains transfer to real-world activities of daily living, with participants performing more tasks correctly than control groups.
Researchers found hyperconnectivity between fronto-parietal regions and less organized flow of information in individuals with chronic moderate to severe TBI compared to healthy controls. The study suggests a causal relationship between working memory tasks and brain injury.
A new study has identified specific genes that are repressed after memory formation, providing insights into how long-term memories are formed. The researchers found that estrogen receptor alpha (ESR1) and Nrsn1 genes play a crucial role in modulating gene-regulatory networks after learning.
Researchers found that adult survivors of pediatric posterior fossa brain tumors performed significantly lower on standardized clinical tests of working memory, and had increased blood-oxygen level dependent activation in prefrontal regions.
A randomized clinical trial found the modified Story Memory Technique to improve memory and everyday functioning in individuals with moderate to severe traumatic brain injury. The study, published by Kessler Foundation, provides first Class I evidence for the efficacy of cognitive training in TBI.
A new study published in Neurology found that people who develop dementia experience a decline in awareness of their memory problems two to three years before the disease onset. The study also identified several dementia-related brain changes associated with this decline.
Scientists at Rice University have developed a solid-state memory technology that allows for high-density storage with minimal computer errors. The memories use tantalum oxide and can store up to 162 gigabits, much higher than other oxide-based memory systems.
Researchers at the University of Basel used computational models to describe human memory processes for the first time. The study identified specific genetic profiles underlying distinct mental processes, such as learning and memory storage.
Researchers found that the same brain cells are engaged during memory formation and retrieval, challenging long-standing debate. The study used molecular imaging to identify specific cells in the hippocampus responsible for accurate memory performance.
Researchers discovered that memory CD4+ T cells linger in the skin for up to a year after resolving Leishmania infection. These skin-resident memory cells help reduce parasite numbers during secondary infections by recruiting blood-borne memory cells, suggesting a new approach to developing anti-Leishmania vaccines.
Scientists from Scripps Research Institute have identified five microRNAs that are necessary for memory formation, while others decrease it, affecting neuronal physiology and nervous system development. The study provides valuable insights into the complex mechanisms of learning and memory.
Research found that children with strong verbal working memory skills can more effectively cover up lies, while those with weaker verbal memory struggle. This link suggests that verbal working memory plays a crucial role in lying.
A study published in PLOS ONE found that men under 45 who consume more trans fats have poorer memory function, with an average drop of 86 words recalled compared to those consuming no trans fats. The researchers linked this association to the adverse effects of trans fats on brain function.
Researchers found an association between cholesterol-lowering drugs and memory loss in the initial 30 days following medication initiation. The link may be due to increased contact with physicians among users of these medications, leading to earlier detection of memory issues.
According to a study by the University of the Basque Country, cognitive decline starts at age 20 but may not be noticeable. Episodic memory deteriorates with age, while semantic and procedural memories remain relatively stable or even improve in some cases.
Researchers at Ruhr-University Bochum recreated memory formation in the hippocampus using computer simulations, challenging the existing model. They found that the CA1 region plays a key role in completing memories, while the CA3 region is not as crucial as previously thought.
A study published in Scientific Reports reveals a direct link between amyloid-beta protein and memory loss in healthy brains, even before physical signs of degeneration appear. The research found that administering amyloid-beta to pond snails caused significant impaired memories, despite no visible brain damage.
A new study by Douglas Mental Health University Institute researchers suggests that the shape of the hippocampus, not its size, is linked to improved memory function. The research, published in Human Brain Mapping, found that individuals with a broader hippocampus tend to perform better on memory tests than those with a smaller one.
A recent study found that women are at a higher risk of persistent memory impairment after a concussion, with brain scans revealing reduced activation in working memory circuits. The study's findings suggest that female gender may be a risk factor for working memory impairment after mild traumatic brain injury.
A study found that sleep disordered breathing can negatively impact declarative memory, making it harder for children to consciously recall learned information. Non-declarative memory, which involves learning new skills through reaction times, was less affected by sleep disturbances.
In a groundbreaking study, researchers used optogenetics to artificially associate the memory of a foot shock with an unrelated environment, triggering increased fear-related behavior. The findings suggest that co-activated cell ensembles can link two distinct memories, paving the way for new treatments of psychiatric disorders.
The study suggests the hippocampus is primarily associated with memory formation and not spatial skills. Patients with hippocampal lesions can perform spatial tasks as long as these tasks don't depend on long-term memory, supported by frontal lobe functions.
Researchers at Saarland University found that even brief power naps (45-60 minutes) can significantly improve retention of learned material in memory. Memory performance remained constant after sleeping, but participants recalled information better than those who didn't nap.
Heavy teen cannabis use linked to changes in hippocampus, poor memory for life events. Young adults who abused cannabis as teens performed 18% worse on long-term memory tests than those who never used the drug.
Scientists from Scripps Research Institute found a mechanism causing long-term memory loss due to age by identifying connectivity defects between neurons, preventing the formation of long-term memories. This discovery could lead to ways of rebuilding those connections to improve memory.
A UT Dallas researcher challenged a long-held scientific theory about the role of the hippocampus in unconscious memory. The study used EEG to test brain wave patterns in amnesia patients with damaged hippocampuses, revealing that the hippocampus is involved in processing unconscious memories.
A new TSRI study explains how booster shots prompt immune memory to improve, a crucial step toward longer-lasting vaccines. The research demonstrates how immune cells evolve and adapt to recognize viruses, leading to more diverse and effective antibody responses.
Researchers at Gladstone Institutes discovered a new memory regulator in astrocytes, which improved memory in healthy mice and prevented impairments in Alzheimer's disease models. The study suggests that targeting A2A adenosine receptors may offer a potential treatment for improving memory.
Scientists have discovered that brain cells in flies regulate both sleep and memory consolidation through a complex interaction. When activated, these cells promote sleep, while deactivated cells enable learning and memory formation.
A new study has identified over 750 genes involved in long-term memory in the worm, including those not previously found. The researchers hope to understand how these genes contribute to memory loss with age and potentially develop compounds to maintain memory.
A recent study published in Journal of Gerontology reveals that cardiorespiratory fitness has a positive impact on long-term memory in older adults. The research found that participants with higher levels of physical fitness performed better on cognitive tasks and showed improved executive function.
A study found that premature birth impairs a subtle but important aspect of memory: recalling context, such as what, when, and where. The hippocampus region is smaller in preterm children, affecting contextual recollection-based retrieval.
The Stanford team created a high-rise chip with multiple layers of logic and memory, potentially leading to computing performance that is much greater than anything available today. The architecture leverages three breakthroughs: new transistor technology, multi-story computer memory, and innovative fabrication techniques.
Research suggests that saving previous information helps free up cognitive resources, improving memory for new information. By 'offloading' old data, individuals can allocate mental resources to learn and remember new material.