Researchers found that patients treated with proton therapy had significantly higher disease-free survival rates (72% vs. 50%) compared to those receiving intensity modulated radiation therapy (IMRT). Tumor control also improved at the longest follow-up for proton therapy-treated patients (81% vs. 64%).
A recent study published in Journal of Cardiovascular Computed Tomography found that advanced CT scanning equipment significantly reduces patient radiation exposure. The use of newer generation, dual-source CT scanners resulted in a 61% decrease in radiation exposure compared to older scanners.
ASTRO Gold Medal winners Mary K. Gospodarowicz, Leonard L. Gunderson, and Nancy J. Tarbell will receive the award for their outstanding work in research, clinical care, teaching, and service. They have made significant contributions to advancing radiation oncology, improving patient outcomes, and promoting global health.
A chemotherapy regimen after radiation therapy improved progression-free survival and overall survival in adults with low-grade gliomas by an average of 5.5 years compared to radiation alone. The study, RTOG 9802, also found better outcomes for patients with oligodendroglioma and females.
Researchers at Wake Forest Baptist Medical Center have successfully treated patients with recurrent lung cancers using a second course of radiation therapy, achieving a cure rate of over 70%. The innovative treatment approach uses precise targeting and high doses to knock the cancer back, offering new hope for these patients.
A study found that women significantly overestimated radiation exposure from a single mammogram compared to other benchmarks. To address this, medical staff should inform patients about the low dose of radiation associated with mammography and provide objective facts to ensure informed decisions.
Researchers used diffusion tensor imaging to measure the volume of optic radiation fiber tracts in 13 healthy volunteers. The study found that the measured optic radiation fiber tract volume was approximately 0.16% and fractional anisotropy value was around 0.53.
The American Society for Radiation Oncology (ASTRO) has issued a new guideline detailing the use of adjuvant radiation therapy in treating endometrial cancer. The guideline recommends postoperative external beam radiation for patients with early-stage disease, and vaginal cuff brachytherapy for those at high risk of vaginal recurrence.
Researchers have processed NASA UV-B radiation data to study its influence on organisms. The dataset provides six variables, including annual averages and seasonal patterns, to help scientists analyze the effects of UV-B radiation on animal and plant species.
Researchers found that women treated with radiation for cervical cancer were at higher risk of developing colon and rectal cancers, with some cases appearing up to 35 years after initial diagnosis. The study suggests new screening guidelines for young survivors, starting eight years after diagnosis.
UT Southwestern researchers found that blocking critical DNA repair mechanisms can slow down tumor growth and increase survival in glioblastoma patients. The study used a drug called NVP-BEZ235, which combined with radiation therapy significantly delayed tumor growth in mice, up to 60 days.
A recent study published in JAMA found that taking daily tadalafil did not prevent erectile dysfunction (ED) in men undergoing radiation therapy for prostate cancer. The study involved 242 men who received either tadalafil or a placebo, and showed no significant difference in ED prevention between the two groups.
Researchers found that just a handful of genetic mutations give E. coli the capacity to withstand ionizing radiation, making them similar to Deinococcus radiodurans. The study demonstrates active DNA repair mechanisms that allow organisms to resist radiation damage.
A study of oropharyngeal cancer patients reveals that radiation therapy can cause significant voice and speech problems. Limiting the radiation dose to the glottic larynx reduces these issues, suggesting a potential strategy for improving post-treatment quality of life.
A thin transparent silicone dressing applied from day one can prevent severe skin reactions during radiation therapy, according to New Zealand research. The dressings create a protective environment for skin stem cells to heal from radiation damage.
A large-scale study found that almost 90 percent of children with low-grade gliomas are alive 20 years after treatment, with a significant difference in survival rates between those who received and did not receive radiation. The study highlights the importance of reducing long-term toxicity risk when treating these tumors.
Researchers have successfully used the Cherenkov effect to capture and visualize radiation beams entering or exiting the human body. This breakthrough technology enables doctors to see the dose of radiation to the skin and detect errors in dosage, potentially reducing side effects like skin reactions during breast cancer treatment.
A new approach dubbed SMART has been shown to more than double three-year survival rates for mesothelioma patients treated with radiation therapy followed by surgery. The treatment approach, which involves an accelerated five-day course of intensity-modulated radiation therapy, reduces the risk of recurrence and improves quality of life.
Patients treated with IMRT experience fewer side effects and lower cancer-related deaths compared to traditional radiation therapy. The study found that IMRT is a safe and beneficial treatment option for patients with head and neck cancer, with improved survival rates and reduced life-threatening recurrences.
A recent study published in BJU International found that radiation therapy used to treat uterine cancer may increase the risk of developing bladder cancer. Patients treated with pelvic radiation therapy had a twice-higher incidence and nearly three times higher death rate from bladder cancer compared to those without radiation.
The Radiation Assessment Detector measured radiation on Mars' surface, revealing an average GCR dose equivalent rate of 0.67 millisieverts per day. The findings also show that most mission radiation exposure will occur during outbound and return travel, posing a challenge for future human exploration.
A team of researchers discovered that abnormal mitochondria may be responsible for cancer cells' resistance to radiation therapy. The study found that a mutation in the E2F gene led to dysfunctional mitochondria that produced less energy, making cancer cells more resistant to radiation-induced cell death.
Researchers found that LIF levels were predictive of NPC patient response to radiation therapy, with patients having higher serum levels of LIF being resistant to treatment. LIF itself promotes NPC progression and radioresistance. Circadian clock proteins BMAL1 also regulate redox proteins preventing oxidative stress damage in neurons.
Researchers found that LIF levels are predictive of NPC patient response to radiation therapy, with patients resistant to treatment having higher serum levels of the cytokine. LIF promotes NPC progression and radioresistance.
CRaTER, an instrument on NASA's Lunar Reconnaissance Orbiter, has made detailed measurements of radiation in deep space. The findings provide crucial data on the high-energy hazards at and around the moon, enabling astronauts to shield against radiation.
Scientists from UNH have published comprehensive findings on space-based radiation hazards using a UNH-led detector aboard NASA's Lunar Reconnaissance Orbiter. The data provide critical information on the radiation hazards faced by astronauts on extended missions to deep space like Mars.
A study published in Physics in Medicine and Biology found that endorectal balloon placement errors can reduce radiation dose coverage, leading to uneven targeting of cancerous areas. Image guidance is crucial to ensure accurate prostate positioning.
A study of 48 patients found higher coronary risks associated with left-sided radiation and supine body position. Targeting baseline cardiac risk factors may reduce radiotherapy-induced heart disease risks.
A comprehensive review of Medicare claims found that nearly all the increase in IMRT for prostate cancer was due to self-referral, leading to unnecessary radiation therapy. Self-referring urologists increased IMRT use by 146%, while non-self-referrers remained unchanged.
Researchers at Georgetown University Medical Center discovered a compound derived from cruciferous vegetables can protect rats and mice from lethal radiation doses. The compound, DIM, also showed potential in preventing or mitigating sickness caused by radiation exposure.
A new study has found that treating chest lymph nodes in early breast cancer patients improves overall survival without increasing side effects. The research involved 4004 patients from 43 centres and found that irradiating the IM-MS lymph nodes gave a better patient outcome than radiation therapy to the breast/thoracic wall alone.
A new process called 'Smart Rounds' optimizes the safety and efficacy of radiation therapy by formalizing multidisciplinary reviews at the beginning of treatment planning. This leads to safer, more individualized radiation treatment plans and better utilization of medical resources.
The project will provide state-of-the-art training in modern, high-quality image-guided radiotherapy, increasing productive research and improving cancer patient care. Researchers from various disciplines will benefit from the six-day workshop, lecture and exercise-based course.
A new study presented at ASTRO's Annual Meeting has identified the Common-Terminology-Criteria-for-Adverse Events (CTCAE) scale as a reliable method for assessing patient reactions to radiation therapy. The study found that using this standardized scale improved consistency among caregivers, enabling more uniform and effective care.
A Mayo-led study has found that sulfasalazine, a commonly prescribed medication for inflammatory bowel disease, fails to reduce diarrhea in patients receiving radiation therapy. The study suggests that the medication may actually increase the risk of diarrhea when used during pelvic radiation therapy.
A new Penn Medicine study shows that proton therapy significantly reduces side effects in pediatric head and neck cancer patients. The results, which followed 25 patients aged 1-21, found no evidence of disease in 76% after 13 months, with only mild side effects such as fatigue and dermatitis.
The study found a significantly lower quality of life in patients who received high-dose radiation therapy (74 Gy) compared to those receiving standard dose (60 Gy). IMRT was associated with a lower decline in QOL compared to 3-D CRT, even a year after treatment.
A shorter course of androgen suppression therapy prior to radiation therapy yields favorable outcomes and fewer adverse effects for intermediate-risk prostate cancer patients. The study confirmed a disease-specific-survival rate of 95 percent when patients received fewer weeks of neoadjuvant total androgen suppression.
A study of 70 pediatric patients treated with proton therapy found high local control rates (83%) and overall survival (95%), with subtotal resection correlated to decreased cognitive and endocrine outcomes. Few patients developed growth hormone deficiency, hypothyroidism or hearing loss.
A study by American Society for Radiation Oncology found that proton therapy can prevent costly side effects in children with medulloblastoma, making it both cost-effective and cost-saving compared to photon therapy. Proton therapy reduced the risk of hearing loss, secondary malignancy, and heart failure.
Jean B. Owen, PhD, receives the highest honor from ASTRO for her extensive work in establishing and analyzing benchmarks for optimal care in radiation oncology. Her contributions include developing clinical performance measures and survey processes to improve quality of care nationwide.
Researchers at University of Texas M.D. Anderson Cancer Center discovered that an inflammatory protein converts glioblastoma cells into their most aggressive form, leading to radiation resistance and reducing treatment effectiveness. Blocking the inflammatory response may improve outcomes for patients.
The American Society for Radiation Oncology (ASTRO) awarded a total of $34,500 to 42 researchers selected for the 2013 Annual Meeting Abstract Awards. The awards recognized outstanding abstracts in seven categories and honored top-rated research in radiation and cancer biology, clinical practice, and radiation physics.
A new study from Children's Hospital of Philadelphia reports proton therapy as an effective, organ-sparing treatment option for children with high-risk neuroblastoma. Protons precisely target tumors while minimizing radiation exposure to healthy tissue.
Researchers at Johns Hopkins Medicine have discovered that neural stem cells can resist radiation and regenerate after damage, potentially restoring lost function in brain cancer patients and individuals with conditions like MS and PD. The findings may lead to new treatments for brain trauma and strokes.
A new technique allows researchers to observe magnesium's atomic-scale changes when exposed to radiation, providing insights into how radiation weakens materials. This discovery may lead to the development of new radiation-tolerant materials for deep space exploration.
Cardiovascular screening is crucial for cancer patients who received chest radiation, especially those at high risk of developing radiation-induced heart disease (RIHD). The European Society of Cardiology recommends regular screenings to detect cardiac abnormalities and reduce the risk of death from coronary artery disease.
Scientists at Vienna University of Technology experimentally confirmed a new theory of heat radiation for ultra-thin optical fibers, showing that smaller objects can't radiate efficiently. This discovery is crucial for nano-devices and aerosol physics.
A new technology has reduced overall radiation exposure from CT scans in children by 37 percent, according to a recent study. The software uses mathematical calculations to determine the lowest possible radiation dose for each patient, allowing radiologists to precisely control the amount of radiation based on patient size.
A new biodegradable implant has shown potential to significantly reduce rectal injury in prostate cancer patients undergoing radiation therapy. The BioProtect Balloon Implant increased the space between the prostate and rectum, reducing radiation exposure by an average of 30%.
The Southwest Research Institute-led Radiation Assessment Detector made detailed measurements of the energetic particle radiation environment inside the spacecraft, providing important insights for future human missions to Mars. The data show an average galactic cosmic ray dose equivalent rate of 1.8 milliSieverts per day in cruise.
A study found that radiation oncology received only 1.6% of the $30.9 billion in NIH-funded grants for cancer research in FY 2013. This disparity highlights an urgent need for increased funding to improve patient survival and treatment outcomes.
A recent study published in JAMA Internal Medicine found that intensity-modulated radiation therapy (IMRT) may not be more effective than conformal radiation therapy (CRT) after prostatectomy. The study compared outcomes of 457 IMRT and 557 CRT patients treated between 2002 and 2007, showing no significant difference in long-term side ...
A new drug has shown significant promise in extending survival when used in combination with radiation therapy for brain cancer patients. The experimental drug, KU-60019, blocks the activation of ATM kinase, leading to enhanced destruction of glioma cells.
The new guideline provides detailed direction on treatment options for prostate cancer patients, including adjuvant and salvage radiotherapy recommendations. It emphasizes the importance of informed consent and patient education on potential side effects and benefits of radiation therapy.
The new ASTRO white paper recommends 10 fundamental elements for safe and effective IGRT practices, including establishing a multi-professional team and performing end-to-end testing for new procedures. The paper aims to improve the safety and effectiveness of image-guided radiation therapy in radiation oncology.
Researchers found that cosmic radiation impairs the ability of cells in the intestines of mice to eliminate oncogenic proteins, substantially increasing development of colorectal tumors. The study suggests that space travelers may be at increased risk of developing colorectal cancer due to prolonged exposure to cosmic radiation.
Cleveland Clinic researchers find that patients with prior chest radiation are nearly twice as likely to die in the years following their heart surgery compared to similar patients who did not undergo radiation treatment. Radiation heart disease can cause coronary artery disease, valve disease, cardiomyopathy, and other cardiac problems.
The ASTRO white paper emphasizes the vital role of patient-specific peer review in improving patient safety and quality of care. The report details suggested targets for peer review throughout various areas within radiation therapy, prioritizing those most likely to impact patient outcomes.
A new study has created a 'toxicity map' of the brain to help protect cognitive function in cancer patients undergoing radiation therapy. The map relates treatment dose to brain function, shedding light on the impact of radiation on cognitive performance.