Two randomized controlled studies show a 65% improvement in treatment group and a 27% improvement in patient-rated measures compared to sham stimulation. The therapy has few side effects, with most participants reporting improvement after receiving treatment.
A large population of U.S. veterans with mild, moderate, or severe traumatic brain injury were found to have a higher risk of developing Parkinson's disease. Those with mild traumatic brain injury had a 56% increased risk, while those with moderate to severe injuries had an 83% and 71% increased risk respectively.
A preliminary study found an investigational drug, RG7916, to increase survival and function in babies with type 1 spinal muscular atrophy by up to 6.5 times the normal amount of SMN protein. The study, which is ongoing, aims to determine if this treatment will provide meaningful benefits for children with SMA.
A new migraine treatment, erenumab, has shown significant promise in reducing headache frequency by over 50% in nearly a third of participants. The study found that erenumab reduced monthly migraine headaches by more than 50% for those who had tried up to four other preventative treatments without success.
A study of over 1,300 women found that entering menopause at a later age was associated with better verbal memory skills. After adjusting for other factors, the researchers found a small but significant difference in memory scores, recalling an average of 0.09 additional words per year.
A study published in Neurology found that people with Parkinson's disease are more likely to be demoralized than those without the disease. Demoralization is distinct from depression, and treatment approaches may differ.
A new study reveals that stroke survivors experience 'hidden' problems like sleep issues, depression, and fatigue, which can significantly affect their well-being. The study found that social support programs and executive function training may improve these areas.
A study published by the American Academy of Neurology found that estradiol therapy via skin patches maintained brain volume and reduced amyloid plaque deposits in women. Meanwhile, estrogen pills caused greater structural changes in the brain, which stopped once treatment was stopped.
Timothy M. Miller receives award for work on effective therapies for ALS, developing method to turn off toxic protein production in brain and spinal fluid. His approach is currently being tested in human clinical trials.
David A. Bennett's work in memory loss research has led to significant advancements in treating and preventing Alzheimer's disease and related disorders. The study's findings are shared globally to develop therapy and identify resilience characteristics.
Women with high physical fitness at middle age were nearly 90% less likely to develop dementia decades later. The study found that highly fit women developed dementia an average of 11 years later than moderately fit women.
Research suggests that living in areas with more sunlight, particularly UV-B rays, can lower the risk of developing multiple sclerosis. Exposure in childhood and young adulthood is also linked to reduced risk. The study found a 45% reduced risk of MS in those living in sunnier climates compared to those with low UV-B ray exposure.
A study suggests that consuming fish rich in omega-3 fatty acids, such as salmon and sardines, may lower the risk of multiple sclerosis. Researchers found a 45% reduced risk of MS among those with high fish intake compared to those with low or no fish consumption.
A study published in Neurology suggests that small blood vessel changes in the eyes at age 60 may predict cognitive decline by age 80. The researchers used a retinal camera to take photos of participants' eyes and found that those with moderate to severe retinopathy had bigger drops in memory and thinking test scores over time.
A preliminary study found that a strict gluten-free diet may reduce the risk of pain in people with gluten neuropathy, with those on the diet scoring higher on mental health assessments. The study involved 60 participants and showed an association between a self-reported gluten-free diet and less pain.
A study suggests that frequent exposure to diesel exhaust may increase the risk of amyotrophic lateral sclerosis (ALS), with a stronger link observed in men exposed for more than 50% of their working life. The research, published in the American Academy of Neurology's meeting program, found no associations among women, highlighting the...
A preliminary study has found an association between central hearing loss and mild cognitive impairment in some people. Researchers discovered that individuals with central hearing loss were twice as likely to have mild cognitive impairment compared to those without hearing loss.
A preliminary study found that following the DASH diet was associated with a lower risk of depression, while a Western diet high in saturated fats was linked to increased depression risk. The study, supported by the National Institute on Aging, suggests that a healthy diet may be an effective way to reduce depression risk and promote b...
Researchers discovered that levels of alpha-synuclein protein are decreased in people with Parkinson's disease, while levels of oligomeric alpha-synuclein are increased. This finding suggests that tears could be a reliable biological marker for the disease.
Researchers found that a simple walking test can accurately diagnose idiopathic normal pressure hydrocephalus (iNPH) and progressive supranuclear palsy (PSP) by assessing participants' gait while performing dual tasks. The study revealed that the test improved diagnostic accuracy to 97% when combined with other assessments.
A recent study found that learning stress-reducing techniques can significantly reduce the frequency of seizures in people with difficult-to-treat epilepsy. Participants who learned progressive muscle relaxation and breathing techniques experienced a 29% decrease in seizures, while those in the control group had a 25% reduction.
Two studies found that women with MS who stop taking natalizumab before or after pregnancy experience increased disease activity and relapse rates compared to those who continue treatment. The risk of miscarriage is also higher in the first trimester, but this rate is small and within the general population range.
A study published in the American Academy of Neurology found that balance and eye movement exercises can help people with multiple sclerosis (MS) improve their balance and reduce fatigue. The exercise program showed significant improvements in balance, fatigue, and dizziness scores compared to a control group.
Researchers found that adding zonisamide to levodopa improved movement symptoms in people with dementia with Lewy bodies without worsening psychiatric symptoms. The study, published in Neurology, suggests a potential new treatment option for this debilitating condition.
A small pilot study found one sign of CTE in a younger person with epilepsy, but no unique characteristics compared to other participants. Researchers suggest that tau protein deposits may not contribute to cognitive impairment in young patients with localized seizures.
Researchers found that people with Parkinson's disease had significantly lower caffeine levels in their blood, even if they consumed the same amount as those without the disease. The study suggests a simple test for early diagnosis could be developed using caffeine levels.
A study published by the American Academy of Neurology found that women taking topiramate during the first trimester had a three times greater risk of giving birth to a baby with cleft lip or palate. The risk was higher for those taking high doses of the drug, and was comparable to lamotrigine.
People with mild cognitive impairment (MCI) may experience improved memory and thinking ability with regular exercise, according to the American Academy of Neurology. The guideline recommends that doctors recommend exercise as part of an overall approach to managing symptoms.
A study published in Neurology found that eating at least one serving of green, leafy vegetables a day was linked to a slower rate of decline on tests of memory and thinking skills. The difference was equivalent to being 11 years younger in age.
A study found that teenage survivors of a terror attack were four times more likely to have migraines and three times more likely to have frequent tension headaches than non-survivors. The study suggests that highly stressful events may lead to ongoing suffering with debilitating headaches.
People with MS who followed a healthy diet were 20% less likely to have severe physical disability and depression. A healthy lifestyle was also associated with reduced risk of fatigue, pain, and depression.
A recent study published in Neurology found that virtual reality training can improve arm and hand movement after a stroke, with results comparable to traditional therapy. The study involved 120 participants who underwent either standard physical and occupational therapy or virtual reality training for four weeks.
A study published in Neurology found that reduced heart blood flow may lead to lower blood flow in the brain's memory centers. The research suggests that mechanisms regulating blood flow become vulnerable with age, potentially leading to cognitive impairment.
Research suggests that chronic inflammation in mid-life may be an early contributor to brain cell loss and memory decline associated with Alzheimer's disease. The study found people with elevated inflammation biomarkers had smaller brain volumes and lower scores on a memory test compared to those without elevated markers.
A recent study published in Neurology found that young hockey players who experienced concussions may still have brain changes three months later. The study showed widespread damage to the white matter of the brain and a 10% reduction in metabolic molecules, highlighting the need for further research into concussion recovery.
A study published in Neurology found that prochlorperazine was more effective than hydromorphone in treating acute migraine, with 60% of patients experiencing sustained headache relief. The study also found no significant difference in opioid addiction rates between the two groups.
A study published in Neurology found a significant increase over 10 years in the percentage of people with stroke who have high blood pressure, diabetes, and other risk factors. The prevalence of these risk factors increased from 88% to 93%, with high cholesterol and drug abuse rates doubling.
A study published by the American Academy of Neurology found that high blood pressure in women's 40s is associated with a 65% increased risk of dementia. Women who developed high blood pressure in their 40s were 73% more likely to develop dementia than those with stable blood pressure throughout their 30s and 40s.
A study of 121 people with Parkinson's disease found that consuming three cups of coffee per day did not improve movement symptoms. The researchers concluded that caffeine cannot be recommended as therapy for movement symptoms of Parkinson's disease.
A recent study published in Neurology found that both high and low levels of magnesium in blood may increase the risk of developing dementia. The research involved 9,569 participants who were followed for eight years, with those having high or low magnesium levels showing a 30% higher risk of dementia compared to the middle group.
A new study suggests that correcting vitamin D deficiency in young and middle-age women can reduce their future risk of multiple sclerosis. Deficient levels of vitamin D were found to be associated with a higher risk of developing MS, with a 39% decrease in risk for each 50 nmol/L increase.
A study found that older adults with poor sense of smell are more likely to develop Parkinson's disease than those who perform better on the test. The researchers also found a stronger link between poor smell and disease in men, but not in women. The test could help identify people at greater risk up to six years before diagnosis.
Researchers found a strong biological link between Epstein-Barr virus and multiple sclerosis (MS) across three racial groups. The study found that blacks, Hispanics, and whites who had mononucleosis were more than two to nearly four times more likely to develop MS than those who did not.
A new study published in Neurology suggests that people who get less rapid eye movement (REM) sleep may have a greater risk of developing dementia. The researchers found a link between lower percentages of REM sleep and an increased risk of dementia, with every percent reduction resulting in a 9% increase in dementia risk.
A new study by the American Academy of Neurology found that telemedicine is as effective as traditional in-person care for people with Parkinson's disease. Virtual house calls provided convenience and comfort without compromising quality of life.
A recent study suggests that men may be experiencing a decline in stroke rates, with the rate decreasing by 31% for men compared to no change for women. The study, published in Neurology, analyzed data from 1.3 million adults and found that overall stroke rates declined significantly for men, but not for women.
A new scoring method developed by researchers can help identify individuals at high risk of serious bleeding after a stroke. The score is based on ten factors, including age, sex, smoking, and prior strokes, and ranges from 2% for low-risk individuals to over 10% for those aged 75-85 with multiple risk factors.
Researchers developed a new, non-invasive method called transcranial magnetic stimulation (TMS) to distinguish between Alzheimer's disease and frontotemporal dementia. The technique accurately diagnosed the conditions with 90% accuracy in most cases.
Researchers found that people with better heart health scores had a higher average brain volume as a percentage of their total head size in middle age. A stronger association was also seen between current smoking and smaller brain volume.
Researchers found elevated levels of two brain injury markers, neurofilament light chain and tau, in active professional fighters compared to retired fighters or non-fighters. These markers may signify permanent traumatic brain injury with long-term consequences.