A study found a strong association between pre- and post-transplant cardio-cerebrovascular diseases, with an estimated hazard ratio of 12.50. Pre-transplant CCVD was independently associated with high non-relapse mortality and inferior survival in patients undergoing hematopoietic cell transplant.
Researchers investigate how mathematics education values vary across cultures, influencing technological advancements and social interactions. The study seeks to understand the significance of mathematics in different societies, emphasizing its importance in shaping our understanding of the world.
A review article summarizing IBS research in China aims to bridge the gap in global literature and improve management of the disorder. The study reveals high prevalence rates, recognized risk factors, and effective treatments, including probiotics and traditional Chinese medicine.
Researchers led by Associate Professor Yuki Fuseya found concrete evidence of Turing patterns at the nanoscale in a bismuth monolayer, resembling stripes on tropical fish. The study paves the way for new research directions in nanoscale physics and could lead to techniques for producing nanoscale devices with self-healing properties.
Researchers used Mendelian randomization to analyze the genetic association between thyroid function and serum lipid profiles, finding a distinct causal relationship. The study highlights the importance of pituitary-thyroid-cardiac axis in diseases related to dyslipidemia.
Trihexyphenidyl, a central anticholinergic drug, shows efficacy in reducing PTSD-related nightmares and flashbacks in 88% and 79% of patients, respectively. The researchers found a rapid onset of treatment within 1-2 days.
Researchers develop a promising surgical technique called SurCOP to repair ventricular septal rupture (VSR) after severe heart attacks. The technique achieved a 100% success rate and improved survival rates by 77.8%, offering new hope for patients with life-threatening fluctuations in blood pressure.
A recent study published in Chinese Medical Journal found that maintaining normal blood pressure over a long period of time significantly reduces the risk of cardiovascular disease. The study analyzed data from a 26-year follow-up of participants and found that cumulative blood pressure levels were a reliable measure of the risk of CVD.
Researchers in China have created a novel risk score to predict relapse of leukemia, allowing for better medical intervention and stratification of patients with different risks. The study analyzed factors such as engraftment of white blood cells, residual cancer cells, and chronic graft-versus-host disease to determine outcomes like 5...
Researchers found that high levels of certain blood lipids are associated with a higher risk of developing esophageal cancer in individuals with a family history of the disease. The study suggests considering 'stratified' analysis to better understand the relationship between serum lipids and cancer.
Research reveals that epigenetic changes contribute to the development of type 1 diabetes, with DNA methylation and histone modifications playing a crucial role. The study suggests that epigenetic markers could be used to monitor disease progression and identify potential therapeutic targets.
The LMO1 gene codes for a protein that regulates RNA production and is implicated in cancer formation. Researchers found that overexpression of LMO1 is associated with poor patient outcomes in different cancers. Further study of LMO1 may lead to targeted therapies for various types of cancer.
A new vaccine called KCONVAC has been shown to be safe and induce antibody production in healthy Chinese adults. The phase 1 and 2 clinical trials demonstrated that the vaccine is well-tolerated and generates a robust immune response, with stronger antibody production seen when participants received their second dose four weeks apart.
A recent study published in Molecular Biology and Evolution reveals that the DNA replication machinery of Mimivirus, a giant virus, is ancient and evolved over time. The research suggests that Mimiviral genes related to DNA replication are subject to purifying selection, indicating their essential role in the organism's survival.
Researchers from China conducted a clinical trial comparing two vasopressor protocols for preventing hypotension post-spinal anesthesia during cesarean sections. They found that norepinephrine infusion significantly reduced maternal hypotension and neonatal tachycardia, as well as improved cerebral oxygenation in newborns.
A study published in Chinese Medical Journal found that generic antihypertensive drugs are as effective as brand-name counterparts in controlling blood pressure over the long term. The results suggest significant cost savings for patients, with treatment using generic drugs being only half as expensive as brand-name treatments.
A recent cross-sectional analysis found a significant association between iron-deficiency anemia and the likelihood of developing insomnia in Chinese adults. Anemia was assessed using hemoglobin levels, while insomnia was evaluated using the Chinese version of the Athens Insomnia Scale.
Researchers summarize growing knowledge on light therapy's mechanism, effectiveness, and applications in treating neurodegenerative diseases like Alzheimer's and Parkinson's. Light stimulation has been shown to restore memory and cognition, improve sleep quality, and reduce symptoms in patients with these conditions.
A comprehensive review of neuropilin-1 research reveals its role in cancer development and proliferation. Inhibiting NRP-1 activity is an attractive idea for treating cancers, with various therapeutic strategies already developed.
The cancer burden in China has undergone a paradigm shift, with rising cases of breast and lung cancers. The country's high incidence rate makes it a priority for policymakers to implement tailored preventive measures, including health education, vaccination programs, and tobacco-control policies.
A new study reveals that sleep disorders are a common symptom of multiple system atrophy, with greater severity correlating to more neuronal damage. The research found specific associations between sleep-related symptoms and MSA severity, including the parkinsonism subtype.
Subgenome fractionation determines hybrid vigor in maize, with one subgenome experiencing more gene loss than the other. This leads to increased protein accumulation and a nonadditive effect on heterosis in F1 plants.
A large multi-center study trains convolutional neural networks to classify breast lesions from ultrasound images, achieving high accuracy rates. The model's performance is compared to that of experienced ultrasonologists, showcasing the potential of AI in speeding up early cancer detection and reducing workload.
A study published in Chinese Medical Journal identified factors that predict patients with STEMI refusing PCI, including age, history of myocardial infarction, and heart rate. The findings suggest that healthcare providers may use these predictors to improve treatment compliance and outcomes for patients with STEMI.
A recent review article published in Chinese Medical Journal explores the associations between psoriasis treatments and risks of cardiovascular diseases. The study finds that some treatments, such as TNF-α inhibitors and methotrexate, may reduce long-term cardiovascular risk, while others, like IL-12/23 inhibitors, may increase it.
Researchers identified various molecular pathways and predictive biomarkers of drug resistance in diffuse large B-cell lymphoma. Tailored therapies can improve prognosis for patients with refractory disease, particularly those with specific clinical features.
A recent study reveals an increase in cancer incidence and mortality rates in China, with rising rates seen in colorectal, pancreatic, and breast cancers. The study highlights the importance of implementing cost-effective approaches for primary prevention and collaborative efforts to reduce the cancer burden.
Researchers identified three m6A modification patterns in HCC, each with distinct metabolic characteristics. These patterns were associated with differences in tumor stage, prognosis, and response to treatment. The study provides novel insights into potential prognostic markers and response to treatment in patients with HCC.
Researchers develop a new protein, 161519 TriKE, to target cold tumors and enhance the immune response. The study found that 161519 TriKE successfully reduced tumor growth and increased overall survival in tumor-bearing mice.
The article discusses the relationship between DNA repair pathways and cancer cells, highlighting five critical pathways and their impact on cancer evolution. The review suggests potential clinical interventions to address pathway damage, offering new insights into cancer treatment.
Cerebral small vessel disease requires a holistic assessment due to its complex symptoms and lack of effective treatments. A multidisciplinary approach can help identify patients at risk and develop management strategies.
China businesses are using digitalization to adapt to the pandemic, expanding stakeholder engagement and prioritizing social responsibility. SMEs can benefit from these strategies to improve performance and survive the crisis.
A new topical treatment, benvitimod cream, has been proven safe and effective for mild-to-moderate plaque psoriasis. In a phase III clinical trial, the cream achieved a 75% decrease in psoriasis size and severity compared to pre-treatment levels.
A recent study published in the Chinese Medical Journal found a high proportion of recent HIV infections among Chinese MSM college students, particularly those under 25 years old. The study suggests that regular HIV testing and TDR testing are crucial to prevent the spread of the disease. The findings highlight the need for early educa...
Scientists propose that widespread semiconducting minerals can absorb sunlight and drive reduction reactions similar to those in biological photosynthesis. These minerals may have played a transformative role throughout primitive Earth, driving the evolution of early lifeforms.
The Chengjiang fauna provides critical evidence for the theory of evolution, with well-preserved soft-bodied animal fossils dating back to the Cambrian period. These discoveries shed light on the emergence of basic human organs, including the mouth, brain, heart, and vertebrae.
The COVID-19 pandemic may alter how students and policymakers view neoliberal globalization, favoring more inclusive online education systems. A new generation of 'glocal' citizens is expected to emerge, navigating between local and global identities.
Scientists propose a new model to explain the formation of the Tibetan Plateau, suggesting a series of 'opening-closing' tectonic events. The study reveals that geological structures in the region were formed through different stages, contradicting the existing plate tectonics theory.
A comprehensive analysis of a mountainous region in Southwest China reveals the driving mechanisms behind changes in soil chemical composition and distribution. Human activities like mining disrupt natural processes, affecting land quality and ecosystem health.
Researchers propose a new therapeutic modality for sepsis by targeting cell-free chromatin in healthy cells. The study found that three cfCh-inactivating agents improved parameters related to sepsis, including increased survival rates in mice.
Scientists from China's top research institutes discovered the novel coronavirus responsible for the Wuhan pneumonia epidemic through next-generation sequencing and bronchoalveolar lavage fluid samples. The virus is 99.8-99.9% similar among all patients' samples, closely related to bat SARS-like CoVs.
A large cohort study confirms that adding transarterial chemoembolization (TACE) to sorafenib improves survival rates in patients with advanced liver cancer, with median overall survival increasing by up to 26%. The treatment combination also shows similar tolerability compared to sorafenib alone.
Researchers have developed a new catalyst that can efficiently split water molecules using nickel-based hydroxide and polyoxovanadate nanoclusters. The resulting material reduces the required overpotential for electrolysis, making it more efficient and potentially game-changing for renewable energy.