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Kessler Foundation


Signal detection theory may be useful for characterizing cognitive fatigue in multiple sclerosis

Kessler Foundation researchers use signal detection theory to characterize cognitive fatigue in multiple sclerosis. The study reveals an association between subjective 'state' fatigue, response bias, and brain activation patterns in both MS and control groups. This finding supports the use of signal detection metrics as an objective me...

SourceKessler Foundation·JournalFrontiers in Behavioral Neuroscience·TypeExperimental study·DateMay 31, 2022

Actigraphy shows promise as objective noninvasive measure of sleep-wake regulation in children with brain injury admitted for pediatric rehabilitation

Researchers developed a new method using actigraphy to monitor sleep-wake cycles in children with brain injury during inpatient rehabilitation. The study found lower rest-activity ratios, suggesting poorer sleep-wake regulation and lower functional status.

SourceKessler Foundation·JournalArchives of Physical Medicine and Rehabilitation·TypeExperimental study·DateApr 29, 2022

Kessler Foundation researchers identify benefits of interpersonal emotion regulation for countering depression in multiple sclerosis

Researchers have demonstrated the efficacy of a six-week interpersonal emotion regulation (IER) intervention for addressing depression often experienced by individuals with multiple sclerosis. IER strategies, such as turning to others for emotional support, significantly reduced depression levels in the treatment group.

SourceKessler Foundation·JournalMultiple Sclerosis and Related Disorders·TypeRandomized controlled/clinical trial·DateApr 28, 2022

Community study reveals unexpected negative correlation between residential greenspace and psychological well-being of people with spinal cord injury

A study revealed a negative correlation between living in areas with low residential greenspace and lower depressive symptoms among people with spinal cord injury. The findings have implications for urban planning and public policy, highlighting the need to understand how community environment factors influence quality of life.

SourceKessler Foundation·JournalSpinal Cord·TypeSurvey·DateApr 11, 2022

New study reveals pandemic-specific depression and anxiety among individuals with multiple sclerosis

A new study published in Multiple Sclerosis and Related Disorders found that individuals with multiple sclerosis experienced increased depression, anxiety, and loneliness during the COVID-19 pandemic. The research suggests that pandemic-related stress may exacerbate mental health issues in MS patients.

SourceKessler Foundation·JournalMultiple Sclerosis and Related Disorders·TypeSurvey·DateMar 23, 2022

Workers with disabilities overcome pandemic setbacks, outpacing people without disabilities to set new records for employment

A new report from Kessler Foundation reveals that workers with disabilities have exceeded pre-pandemic employment levels to reach historic highs, while those without disabilities still lag behind. The data show that labor force participation rates for people with disabilities increased from 33.6% in 2019 to 35.1% in 2021, outpacing the...

Survey heightens concern about pandemic’s impact on education of students with autism

A recent online survey found that pandemic-related school closures have a disproportionate negative impact on students with autism. The study reveals differences in the psychological impact of the pandemic on neurotypical and autistic children, highlighting the need for alternative ways to support autistic children's educational goals.

SourceKessler Foundation·JournalFrontiers in Education·TypeSurvey·DateFeb 17, 2022

Treatment for spatial neglect based on immersive virtual reality offers advantages over traditional therapies

Researchers developed a user-centered virtual reality system to engage stroke survivors with spatial neglect in intensive therapy, showing promising results. The system uses head-mounted displays and hand-tracking technology to deliver standardized treatment in an engaging environment.

SourceKessler Foundation·JournalAnnals of Physical and Rehabilitation Medicine·TypeExperimental study·DateFeb 11, 2022

Kessler Foundation scientists explore evidence for improving outcomes for prism adaptation therapy in stroke survivors

Researchers analyzed fMRI studies on healthy individuals and stroke survivors to understand the neural mechanisms underlying prism adaptation therapy. The study found differences in brain activity patterns between healthy individuals and those with spatial neglect, suggesting a shift in spatial processing to the left hemisphere.

SourceKessler Foundation·JournalBrain Sciences·TypeMeta-analysis·DateFeb 3, 2022

Researchers report cognitive effects of aerobic exercise on persons with significant memory loss caused by traumatic brain injury

Researchers found that moderate aerobic cycling improved auditory verbal learning and processing speed, as well as increased volumes of the hippocampus and cerebellar cortex. The study suggests exercise interventions may be an attractive option for improving cognitive function in individuals with traumatic brain injury.

SourceKessler Foundation·JournalNeurocase·TypeRandomized controlled/clinical trial·DateJan 24, 2022

Pilot study of exercise and cognition in progressive multiple sclerosis highlights need to assess outcomes of randomized controlled trials

A pilot study of exercise and cognition in progressive multiple sclerosis found that cardiorespiratory fitness and free-living physical activity were not associated with improved cognitive performance. The study, which analyzed data from 240 individuals with progressive MS, suggests that other mechanisms may be at play.

SourceKessler Foundation·TypeRandomized controlled/clinical trial·DateDec 16, 2021

Treadmill exercise training shows promise for managing cognitive effects of multiple sclerosis

Researchers found improvements in verbal learning and memory and preservation of hippocampal volume in participants with relapsing-remitting multiple sclerosis after 12 weeks of supervised treadmill walking exercise. A targeted pilot randomized controlled trial demonstrated the effectiveness of this intervention for managing cognitive ...

SourceKessler Foundation·JournalContemporary Clinical Trials·TypeExperimental study·DateDec 3, 2021

Prevalence of spatial neglect prompts call for screening survivors of right and left brain strokes

A systematic review found spatial neglect to be prevalent among 29% of unilateral stroke survivors, with higher rates in right brain strokes and ecological assessments. This condition impairs cognitive and motor functions, slowing rehabilitation progress and increasing risk for injury.

SourceKessler Foundation·JournalAnnals of Physical and Rehabilitation Medicine·TypeLiterature review·DateSep 27, 2021

Remote learning shown to be effective for preparing clinicians as wheelchair-skills trainers

A new study by Spinal Cord Injury Model System investigators found that remote wheelchair-skills training increases clinician confidence in teaching peers. The training program improved trainees' ability to navigate real-world spaces, empowering them to engage with their communities. This innovative approach has the potential to expand...

SourceKessler Foundation·JournalArchives of Physical Medicine and Rehabilitation·TypeObservational study·DateAug 30, 2021

Majority of people with spinal cord injury use complementary and integrative healthcare

A study published in Archives of Physical Medicine and Rehabilitation found that 80% of people with spinal cord injury use complementary and integrative healthcare approaches. The most common reasons for use were general health and wellness, pain management, and to improve mobility and flexibility. However, there is a need for more res...

SourceKessler Foundation·JournalArchives of Physical Medicine and Rehabilitation·TypeSurvey·DateAug 25, 2021