Diet sets the ferroptosis threshold of T cells
Researchers found that dietary fat balance influences T-cell membrane oxidation, making them more vulnerable to ferroptosis. This can weaken immune responses, including CAR-T cell therapy effectiveness.
Researchers found that dietary fat balance influences T-cell membrane oxidation, making them more vulnerable to ferroptosis. This can weaken immune responses, including CAR-T cell therapy effectiveness.
Shanghai Jiao Tong University Journal Center invites experts to participate in a 2026 survey on global engineering frontiers in energy and mining engineering. The survey aims to identify emerging trends and guide the development of industries. Participants can select up to three frontier topics within their area of specialization.
The symposium aims to showcase cutting-edge academic achievements and innovative applications from the global energy community. It will tackle key energy challenges through in-depth academic dialogue.
Single-cell sequencing resolves responses in various tissues and organs, identifying cells that respond to different exercise modes and doses. This technology enables the development of precision exercise biomarkers for applications in muscle repair, immune regulation, and chronic disease research.
Researchers have developed a novel fluorine-doped CoFe layered hydroxide catalyst that outperforms traditional materials in seawater electrolysis, offering improved durability and activity for hydrogen production. The material's 'chlorophobic' barrier suppresses corrosion while sustaining OH accessibility.
The editorial highlights the persistent gap between policy and action on physical activity, despite decades of evidence and well-developed frameworks. The authors propose an independent Global Alliance for the Promotion of Physical Activity to bridge this gap through capacity-building and measurable implementation outcomes.
Researchers have identified several groups of metabolites involved in embryo implantation, including glucose, lactate, lipid-derived molecules, amino acids, and neurotransmitters. These metabolites help create a local environment that supports embryo invasion into the uterine lining and promotes tissue remodeling and immune tolerance.
Researchers introduce a 'failure-mechanism-oriented robustness optimization' framework to address coupled multimode failures and optimize superhydrophobic sensor performance. The framework establishes key quantitative benchmarks for next-generation amphibious flexible sensing, enabling exceptional metrics of up to 10,000 gauge factors ...
Researchers develop a breakthrough electrolyte system using anion-diluent decoupled solvation chemistry, achieving improved battery life, safety, and voltage tolerance. The new electrolyte design enables compact contact ion pairs, delivering intrinsically higher oxidation stability and faster Li+ desolvation kinetics.
The study proposes a three-stage maturity model for AI integration in pathology, highlighting key barriers to clinical translation: data fragility, workflow misalignment, and institutional trust deficits. Infrastructure-first AI, workflow-embedded intelligence, and adaptive governance are proposed pathways toward sustainable clinical i...
Disturbed sleep impairs BBB integrity through oxidative stress, neuroinflammation, and gut microbiota dysbiosis. Treating underlying sleep disorder is the most direct approach, while mechanism-based interventions show promise for future development.
Researchers develop novel approach to fabricate large-scale single-crystal heterojunction arrays with precise control over pixel size, arrangement angle, and crystal orientation. The method enables exceptional quality, self-powered photodetector arrays with remarkable metrics, and high-performance optoelectronic applications.
Researchers have presented a comprehensive review on the use of 2D materials to enhance lithium–oxygen battery technology through heterogeneous ORR/OER catalysis. The unique properties of 2D materials overcome traditional limitations, delivering remarkable metrics and enabling reversible Li2O2 formation with minimal overpotential.
Researchers developed a breakthrough bionic wound dressing that combines protective function, wearing comfort, and efficient antibacterial activity. The dressing achieves 97.1% antibacterial efficacy against Staphylococcus aureus and promotes near-complete wound closure within 11 days.
The P/Ce-NC catalyst accelerates Li+ desolvation, unlocking rapid sulfur redox kinetics and unprecedented cycling stability. The dual electronic modulation mechanism enhances interaction between Ce and solvent molecules, weakening the Li+-solvent coordination and reducing the desolvation energy barrier.
Researchers developed a buried interface engineering strategy to directly tame lattice strain at its origin, improving perovskite stability and power conversion efficiency. The innovative design promotes a low-strain lattice framework through optimized molecular modification, chemical passivation, and robust Lewis acid-base interactions.
Psittacosis is experiencing a notable resurgence in China, driven by increased diagnostic awareness and metagenomic next-generation sequencing. The disease has significant gaps in current knowledge, including inadequate characterization of molecular epidemiology and lack of unified national surveillance framework.
A new study maps future risk of dengue transmission in Costa Rica by analyzing climate factors and epidemiological records. The research reveals a complex interplay between seasonal weather patterns and disease transmission, highlighting the need for locally informed, seasonally adaptive strategies.
Researchers have engineered a moderately hydrophobic polymer protective layer that resolves the challenges of zinc anodes in rechargeable zinc-ion batteries. The PDMAG layer enables vertical aligned, thick, and highly ordered Zn facets, suppressing dendrite growth and facilitating Zn utilization.
Researchers developed a Pd-Ni5P4/DCEFS system that bridges the gap between sensitive sensing modules and high-performance therapeutic actuators. The closed-loop mechanism dynamically modulates hydrogen release based on endogenous NO concentration, creating an ideal microenvironment for macrophage polarization and wound healing.
Researchers developed a highly efficient photocatalyst for solar-driven CO₂ conversion using a ZrO₂/CdS core-shell composite. The catalyst achieves nearly 100% selectivity for carbon monoxide production, overcoming bottlenecks in industrial application.
A genome-wide mixed methods study identifies shared genetic variants across substance use disorders, suggesting overlapping biological processes. The analysis reveals new genetic regions and implicated genes in key neurobiological processes, including reward processing and behavioural regulation.
Researchers developed a solution to improve the mechanical stability of perovskite/silicon tandem cells, achieving a record-breaking power conversion efficiency of 30.04%. The uniform submicron pyramids on ultrathin silicon wafers significantly improved device performance and flexibility.
Researchers have developed a gradient-laminated ceramifiable silicone foam composite that bridges the gap between passive insulation and dynamic impact resistance. The material exhibits exceptional thermal insulation and robust mechanical durability under extreme conditions, making it suitable for constructing intrinsically safe lithiu...
A landmark review proposes cytoskeletal prestress homeostasis as fundamental biological principle regulating cellular behaviors, including cell stiffness and gene transcription. Dysregulated prestress homeostasis is linked to cellular senescence and cancer metastasis.
Researchers have discovered a new subtype of foam cells that form in early atherosclerosis, driven by mechanical stacking stress. These coralthelial cells promote inflammation and accelerate lesion development. The study offers promising therapeutic targets and novel prevention strategies for cardiovascular disease prevention.
Researchers developed a multifunctional protective layer to overcome limitations of high-capacity, lithium-rich Mn-based oxide (LRMO) materials. The new cathode achieves exceptional fast-charging capability, long-term cycling stability, and high energy density with minimal Sc consumption.
Researchers have developed a novel nano-space confinement strategy for hard carbon anodes, overcoming limitations in sodium-storage mechanisms. The optimized material delivers high reversible capacity and maintains rate capability, making it suitable for next-generation sodium-ion batteries.
Researchers have developed a novel Sn-FB QSE that achieves near-unity Na+ transference number alongside high conductivity, surpassing conventional systems. The dual-mediator architecture regulates bulk ion transport and bilateral interface chemistry, enabling rapid Na+ diffusion and suppressing electrolyte degradation.
Researchers developed smart-responsive superwettable materials for efficient oil-water separation, achieving high efficiency and reversibility. The materials combine selectivity of static membranes with adaptability of living biological systems.
Researchers develop a new material design to overcome kinetic and stability issues in sodium-sulfur batteries, enabling fast-charging capabilities. The innovative pisiform homojunction creates a p-n interface that accelerates polysulfide conversion and stabilizes battery performance.
Researchers develop a highly adhesive hydrogel that reinforces the interaction between functional layers and electrodes, improving electrical output performance and mechanical stability. The resulting device exhibits ultra-long-term stable operation, anti-drying, anti-freezing, and anti-swelling properties.
Artificial intelligence can bridge the gap between rich multi-scale data generated by modern exercise biomedicine and urgent clinical need for tailored exercise prescriptions. Four key AI modeling paradigms, including time series learning, multimodal fusion, causal inference, and reinforcement learning, are examined.
Researchers have developed a dual-functional interface that combines zincophilicity and hydrophobicity to stabilize the zinc metal anode in aqueous zinc-ion batteries. This design allows for dendrite-free batteries with improved safety and cycle life, making it a promising candidate for the next generation of energy storage technologies.
Researchers develop a leaf-inspired strategy to create ultra-stretchable metal films by manipulating cracks, governing electromechanical performance. The bioinspired conductors offer a low-cost, robust, and highly tunable solution for AI-integrated healthcare monitors and soft robotic skins.
Researchers created a multifunctional material platform by integrating 2D MXene nanosheets with liquid metal, enabling both high conductivity and electrochemical activity. The MXene-assembled liquid metal hybrid microparticles (MLHMs) demonstrated excellent interfacial adhesion and stability, making them suitable for real-world dynamic...
A breakthrough solution has been unveiled for decarbonizing the transportation sector, particularly heavy-duty marine shipping. The Ammonia Thermal Atmosphere Compression Ignition (TACI) combustion mode achieves highly efficient, stable and clean ammonia diffusion combustion under mild operating conditions.
Researchers develop bond-centric framework to selectively activate C-H and C-C bonds in biomass and plastics for sustainable valorization. The review proposes a roadmap for industrialization, focusing on precise bond discrimination, high solar-to-chemical energy conversion efficiencies, and hybrid systems.
Researchers develop silver-single-crystal silicon nanodisk antenna to overcome the picosecond tail in ultrafast optics. By extracting energy before lattice heating, they achieve modulation in the tens-of-femtoseconds range.
A new study found that fexaramine, a gut-targeted drug, improved both metabolic and reproductive problems in PCOS model mice. The treatment restored disrupted menstrual cycles, reduced ovarian follicles, and lowered testosterone levels, suggesting a potential new approach to treating PCOS.
Researchers used advanced modelling to identify key losses in perovskite/CIGS tandems, proposing a three-step optimization strategy to reach theoretical potential. The study also considered real-world operating conditions and found the devices maintain high efficiency under diffuse light and varying temperatures.
Climate-driven instability is transforming dengue transmission in Vietnam, requiring a new approach to surveillance and early warning systems. Researchers propose a hybrid system incorporating climatic thresholds, probabilistic modeling, and One Health practices to proactively reduce outbreak scale.
Researchers developed a novel smart hydrogel framework that can store multiple pages of information, revealed under different environmental conditions. The technology uses light-induced crosslinking and anti-opal structural colors to create a highly secure and aesthetically striking platform for information encryption.
The first annual Experimental Therapeutics meeting will bring together leading investigators to share experiences in translating scientific discoveries into clinical success. The event will take place from June 1st to 4th, 2026, at Ruijin Hospital in Shanghai, China.
Developed by researchers at Shanghai Jiao Tong University, this sensor uses anisotropic reduced graphene oxide aerogel to detect subtle physiological signals while maintaining a broad range of force detection. The sensor exhibits record-breaking performance and multi-functional integration capabilities.
Researchers developed a dual-functional coating composed of palladium nanoparticles on a graphitic carbon nitride matrix, which blocks water-induced corrosion and regulates zinc deposition at the atomic level. This 'hydrophobic-zincophilic' design provides a generalizable strategy for high-performance, long-lasting zinc-ion batteries.
Researchers develop high-performance, bifunctional electrocatalyst using crystalline Ni3S2 nanorods and low-crystalline NiCoSx, enabling efficient overall water splitting. The catalyst's built-in electric field promotes faster electron transfer and optimizes adsorption energies.
This innovative material combines the mechanical flexibility of an organic hydrogel with exceptional microwave absorption properties. The synergy between MXene and carbon dots provides a powerful tool for managing electromagnetic pollution in wearable electronics.
Researchers create bifunctional electrocatalyst with cobalt phosphide heterojunctions for efficient water splitting, rivaling expensive commercial catalysts. The innovative architecture enables stable hydrogen production at a fraction of the cost.
Researchers developed a dual-site functional orchestration strategy using 2-imidazolidone to stabilize the zinc anode and eliminate the polyiodide shuttle effect. This approach enables synergistic modulation of both electrodes, resulting in improved durability and performance for large-scale energy storage applications.