Research reveals oxytocin neurons in mouse brain modulate object recognition memory, with activation boosting long-term memory and implicating Alzheimer's disease. Oxytocin's role in social memory also highlighted, suggesting a potential link to loneliness or limited social engagement.
A team of researchers from Tokyo University of Science employed a new 'transmetallation' technique to synthesize lateral heterojunctions of 2D coordination nanosheets. The method enables the creation of ultrathin electronic devices with unique properties, paving the way for innovative devices.
Researchers from Tokyo University of Science identify Cpeb4 protein's crucial role in mRNA splicing and osteoclast differentiation, shedding light on bone disease mechanisms. The study's findings may lead to new diagnostic techniques and treatments for conditions like osteoporosis.
Scientists found that short-chain fatty acids produced by gut bacteria suppress allergic reactions by modulating mast cell activation and epigenetic modifications. This study provides new insights into the relationship between diet and immune system regulation, with potential applications in allergy treatment.
Researchers at Tokyo University of Science have developed a novel approach to synthesize dibenzothiophene s-oxides, which feature highly reactive functional groups. This method surpasses conventional methods and enables the creation of a wide range of molecules with diverse properties.
Researchers developed a novel deep learning method to study crystal structure and molecular interactions of perchlorate salts. The analysis revealed that the explosives' nature is linked to chemical bonding and intermolecular interactions.
A recent study by Tokyo University of Science researchers has uncovered the mechanisms by which plants regulate the production of reactive oxygen species (ROS). The findings, published in Physiologia Plantarum, reveal that ROS-generating enzymes are activated through two conserved mechanisms involving calcium ions and phosphorylation, ...
Researchers developed a novel hybrid approach combining traditional mathematical methods and cutting-edge machine learning to improve EIT analysis of building structures. The new method, called AND, reduces errors in reconstructing foreign objects' position and size compared to conventional EIT methods.
A team of researchers has uncovered the magnetic phase diagram of non-Heisenberg-type quasicrystals, revealing new insights into their unique properties. The findings open up new doors for understanding the intricate interplay between magnetic interactions in these materials.
A recent study by Tokyo University of Science has identified central emotions across languages through word association-based colexification networks. The researchers found that concepts like GOOD, WANT, BAD, and LOVE are associated with many other words representing emotions.
Researchers from Tokyo University of Science discovered that manipulating polyamines enhances the functional profiles of monoclonal antibodies. The study found that controlling polyamine levels increases IgG galactosylation, leading to improved therapeutic efficacy.
Researchers at Tokyo University of Science develop an edge computing device that processes signals in real time using physical reservoir technology, achieving faster data processing and lower computation costs. The device demonstrates enhanced learning capabilities, making it promising for applications in edge computing.
A new study introduces a machine learning-aided non-invasive imaging technique that can rapidly visualize liver fat distribution, enabling early diagnosis and treatment of liver diseases. The method uses near-infrared hyperspectral imaging and machine learning to differentiate between types of lipids in the liver.
Researchers developed a new framework to understand small-scale turbulent flows, shedding light on the chaotic butterfly effect. The framework uses chaos theory and synchronization theory to explain the critical length scale, which affects data assimilation methods.
Researchers from Tokyo University of Science developed a novel, low-cost hydrogel using seaweed extract that prevents wound expansion and promotes healing. The hydrogel demonstrates significantly lower adhesion and swelling compared to conventional hydrogels, making it an excellent alternative for treating skin wounds.
The Tokyo University of Science team has created a device that enables the simultaneous evaluation of many cancer cells, allowing for rapid and accurate analysis. The system, called cROT, increases throughput to 2,700 cells per hour, making it more than 100 times faster than traditional methods.
Researchers developed a lightweight wearable balance exercise device to improve reactive postural control in older adults, reducing the risk of falls. The device uses pneumatic artificial muscles to generate unexpected perturbations, resulting in improved peak displacement and velocity.
Researchers found that cancer cells with multiple mutations alter cell competition, allowing them to infiltrate and form highly invasive tumors. The study identified a key mechanism, MMP21, which promotes the production of diffusely invasive cancer cells.
A deep learning model developed by Tokyo University of Science researchers can accurately identify horsehair crab genders, enhancing conservation and farming efforts. The AI approach achieves high precision in classification, even when observing shell side, and could be applied to other species.
Researchers developed a deep learning model that can identify previously unknown quasicrystalline phases in multiphase crystalline samples. The model achieved a prediction accuracy of over 92% and successfully detected an unknown phase in Al-Si-Ru alloys.
Researchers found that cultivating Euglena in tomato juice resulted in high cell densities and tightly packed chloroplasts, outperforming other beverages. The nutrient composition of tomato juice is suitable for Euglena growth, offering a promising solution to the shortage of animal protein and potential health benefits.
Researchers at Tokyo University of Science developed nanostructured hard carbon electrodes using inorganic zinc-based compounds, which deliver unprecedented performance and significantly increase the capacity of sodium- and potassium-ion batteries. The new electrodes improve energy density by 1.6 times compared to existing technologies.
Scientists create a low-cost, room-temperature single-photon light source by doping optical fibers with ytterbium ions, paving the way for affordable quantum technologies. The innovation overcomes cooling system limitations, enabling applications in true random number generation, quantum communication and high-resolution image analysis.
Scientists have developed a technique to restore the function of human-derived GPCR proteins in yeast cells, which could accelerate research and lead to more effective treatments. The approach, using error-prone polymerase chain reaction, introduces random mutations that enhance protein stability and function.
Researchers have discovered a novel enzyme family related to bacterial pathogenicity in Gram-negative bacteria. The study revealed that enzymes involved in OPG synthesis and regulation play crucial roles in bacterial infection capability.
Researchers have developed a metal nanocluster-based separator for lithium-sulfur batteries, accelerating electrochemical kinetics and improving capacity and cycling stability. The technology has the potential to increase the adoption of sustainable energy storage systems, including electric vehicles and renewable energy.
Researchers at Tokyo University of Science have discovered a method to generate molecular ions from an ionic crystal by bombarding it with positrons. This breakthrough could lead to new applications in materials science, cancer therapy, and quantum computing.
Researchers at Tokyo University of Science have uncovered a novel mechanism for sorting endocytic cargo, revealing a specific compartment within the trans-Golgi network that determines the fate of cargo. This discovery has implications for understanding basic life processes and diseases caused by disruptions in endocytosis.
Associate Professor Tadashi Ando from Tokyo University of Science conducted a study to test the performance of OPC and OPC3 water models, evaluating their shear viscosities and comparing values to experimental calculations. The calculated viscosities for both models were very close, with notable accuracy at temperatures above 310 K.
A Japanese research team used advanced analytical techniques to study the electrochemical phenomena in aqueous potassium-ion batteries. They found that solid-electrolyte interphases form a passivating layer, suppressing hydrogen evolution and improving stability.
A research team from Tokyo University of Science has developed a novel synthesis route to produce a wide variety of sulfinate esters using readily available compounds. The new method uses thioesters, which are odorless and stable, eliminating the challenges associated with handling thiols.
Researchers from Tokyo University of Science have developed a catalyst support based on titanium dioxide powder to facilitate effective CO2 reduction. The study demonstrated increased hydrogen production and enhanced catalytic performance with silver nanoparticles loaded onto the TiO2 surface.
A newly discovered fungus has been found to transform the toxic compound patulin into less harmful byproducts, offering potential solutions for controlling its presence in food products. The fungus, identified as Acremonium sp., was shown to degrade patulin into desoxypatulinic acid and other compounds, which are significantly less toxic.
Scientists developed a novel technique to evaluate carbon particle dispersion in battery electrode slurries, enabling enhanced battery electrodes. The study's results show that measuring viscosity and electrochemical impedance can provide insights into dispersibility.
A team of researchers developed a novel method that leverages temporal characteristics of blood pulse to estimate heart rates with improved accuracy, especially in scenes with ambient light fluctuations. The proposed method showed a 36.5% improvement in estimation accuracy compared to conventional methods.
Researchers from Tokyo University of Science have developed an innovative method to synthesize azide compounds with a protected azido group, facilitating the efficient synthesis of organonitrogen compounds. This novel approach enables the creation of a wide range of azides through transformations with various electrophiles.
Scientists develop two novel SCAMs with enhanced stability and excellent Fe3+ sensing ability. The materials exhibit a quantum yield of up to 9.7% and exceptional stability in water, making them suitable for environmental monitoring.
Researchers found that mutations in the Pro1 protein enable the rice blast fungus to thrive through increased conidia release. This finding suggests an adaptive advantage for the pathogen, potentially linked to its loss of female fertility.
Researchers at Tokyo University of Science successfully synthesized tanzawaic acid B in large amounts, paving the way for new antibiotic development. The breakthrough method could lead to creation of various compounds for pharmaceuticals, including new antibiotic candidates.
A novel microfluidic sweat lactate sensor has been developed to measure sweat lactate levels continuously during exercise without interruptions from air bubbles. The device uses a larger-than-usual sweat reservoir to trap air bubbles, preventing them from contacting the sensors' electrodes.
Researchers examine whether robots and AI can replicate the ethical concepts attributed to human nurses, including advocacy, accountability, cooperation, and caring. While AI can inform patients about medical errors and present treatment options, it questions its ability to truly understand and empathize with patients' values.
Researchers at Tokyo University of Science developed a novel wearable biosensor that can monitor sweat electrolyte levels, providing insights into the body's electrolyte balance. The sensor can be seamlessly applied to textiles and transmits measurements wirelessly.
Researchers develop an ionic device utilizing redox reactions to achieve a high number of reservoir states, enabling efficient complex nonlinear operations. The device demonstrated remarkable performance in solving second-order nonlinear dynamic equations and predicting future values with low mean square prediction error.
The study reveals that the midgut gland of Japanese scallops is a valuable source of fucosylated heparan sulfate, exhibiting anticoagulating and neurite outgrowth-promoting activities. Fuc-HS shows resistance to GAG-degrading enzymes, indicating its unique structure with a fucosyl group attached to GlcA.
A team of Japanese researchers has successfully developed a recycling photoreactor that enables the synthesis of optically pure compounds with high yields, achieving an optical purity of 98-99%. The system uses a two-step rapid photoracemization process and can produce enantiomerically pure chiral sulfoxides in yields higher than 80%.
Researchers developed a novel hybrid protein complex by binding lysozyme to copper for enhanced reactive oxygen species (ROS) removal. The CuST@lysozyme hybrid protein showed high SOD activity and stability in biological fluids, paving the way for its therapeutic applications.
KNT-127 exhibits anti-stressing and anti-depressant effects in mice, improving social interaction and reducing stress-induced hormone levels. The agent suppresses neuronal inflammation and newborn death without affecting neurogenesis.
A team of researchers found that prosumers, who produce their own electricity, can lower transmission charges when generating less energy. However, when producing a large amount of renewable energy, transmission charges increase. The study suggests levying a per-MWh tax on prosumer consumption to reduce the likelihood of death spirals.
Researchers at Tokyo University of Science have discovered a novel gold-gallium-dysprosium quasicrystal that exhibits ferromagnetic properties, tunability and high phase purity. The discovery opens up new frontiers in magnetic materials science, with potential applications in spintronics and magnetic data storage.
Scientists at Tokyo University of Science created a fracture-resistant alloy through heat-treatment, exhibiting improved elastocaloric properties and resistance to cyclical loads. The Cu-Zn-Al alloy showed significant increases in grain size, leading to enhanced cooling capabilities and paving the way for innovative refrigeration systems.