Researchers at Tokyo University of Science have developed a novel platinum nanocluster catalyst that exhibits 2.1 times higher oxygen reduction reaction activity than commercial catalysts. The study reveals that the high activity is due to the electronic structure of surface Pt atoms, which is suitable for ORR progress.
Scientists discover carbonated water's impact on low-methoxy pectin hydrogel formation and properties. The study shows that CO2 from carbonated water increases mechanical strength and gelation rate of hydrogels.
A study led by Tokyo University of Science researchers identified Dectin-1's role in promoting colorectal cancer by enhancing PGE2 production and suppressing IL-22BP expression. The study used mouse models and clinical samples to validate the findings, which have immediate clinical implications for CRC patients.
Researchers from Japan have synthesized two di-superatomic molecules composed of Ag and evaluated the factors involved in their formation. The study found that a twist between the two icosahedral structures stabilizes the nanocluster by shortening the distance between them. Additionally, the presence of Pd and Pt central atoms was foun...
Researchers from Tokyo University of Science reveal the crystal structure of centromere-associated protein E (CENP-E), a promising target for inhibitor therapy. The discovery is expected to facilitate the development of anticancer drugs with fewer adverse effects on patients.
Researchers found that immune checkpoint inhibitors increase the mobilization of overlapping tumor-reactive CD8+ T cells, leading to antitumor effects. The diverse subset of T-cell clones plays a key role in this response, with polyclonal clones exhibiting more proliferative potential and contributing to effective treatment outcomes.
Scientists at Tokyo University of Science generate vector vortex light beams and imprint their structure on electron spins in a semiconductor solid, creating helical spatial structures. This breakthrough enables higher information storage capacity by exploiting effective magnetic fields alongside structured light beams.
Scientists have found that antibodies targeting βII-spectrin on mesangial cells are the trigger for IgA nephropathy. This discovery enables blood-based diagnosis and may lead to improved treatments.
Researchers at Tokyo University of Science used computer simulations to clarify why L-alanine was preferred over D-alanine during primordial RNA aminoacylation reactions. The study revealed that L-amino acid had more electrostatic stability in its transition state, providing a plausible reason for the selective aminoacylation.
Researchers have developed a novel 3D covalent organic framework, TUS-64, with the largest pore size and lowest density ever recorded. The material shows promise as a drug nanocarrier vehicle, with high capacity to hold drugs and sustained release rate.
Scientists studied F1-ATPase function in bacteria to clarify the angle of rotation during ATP hydrolysis. The study revealed three sets of short and long dwells associated with different intervals per revolution, resolving a long-term debate over the ATP-cleavage shaft angle.
Scientists at Tokyo University of Science develop a novel technique to evaluate the electric double layer effect, achieving carrier modulation and improved switching response speed control. The EDL effect is reduced with certain electrolytes, leading to faster charging times.
TUS researchers develop novel method to create multi-walled CNT wiring on plastic films under ambient conditions, enabling flexible devices and energy conversion devices. The proposed method produces high-quality wires with varying resistance values.
Scientists have genetically modified potatoes and tomatoes to produce betacyanin, a pigment with anti-inflammatory properties. The transgenic vegetables demonstrated enhanced accumulation of the pigment, which showed improved effects in reducing inflammation in macrophage-like cells and murine models of colitis.
A new study by Tokyo University of Science researchers examines the connection between political regime changes and social mobility during the Meiji Restoration. The results show that social mobility increased before the consolidation of a new political power, with meritocracy playing a key role in this period.
Researchers from Tokyo University of Science discovered β-damascone, a natural aroma compound found in rose fragrance, modulates dendritic cell functions and reduces inflammatory cytokine production. The study showed β-damascone inhibits antigen-dependent activation and Th1 cell development, as well as ear inflammation in mice models.
Researchers at Tokyo University of Science have found a promising cathode material for magnesium rechargeable batteries, achieving better cyclability and high battery capacity. The Mg1.33V1.67O4 system with substituted vanadium and manganese shows superior charge-discharge properties.
The iCPH platform combines physical and cyber elements to capture human motions, using musculoskeletal analysis and machine learning. It generates contact motion networks for humanoid robots and simulates human behaviors, enabling smooth interactions with humans.
A new secure computation method is introduced, allowing for decentralized computation of encrypted data on a single server without significant computational cost. This method addresses drawbacks of existing methods, providing faster and more secure computations.
A new digital twin of laser-directed energy deposition repair technology has been developed to improve industrial sustainability. The system automatically determines optimum forming conditions, reducing metal powder waste and increasing the effectiveness of the repair process.
A team of researchers from Tokyo University of Science developed a super-hierarchical and explanatory analysis method for magnetic reversal processes, enabling the detection of subtle microscopic changes. The new algorithm can predict stable/metastable states in advance and improve the reliability of spintronics devices.
Researchers developed a simple and accurate method for markerless gait analysis, combining RGB camera-based pose estimation with IMU sensor data. The new technique outperformed existing methods in measuring gait parameters and joint angles, showing significant promise for clinical settings and diverse applications.
Researchers at Tokyo University of Science have developed a unique 3D COF with scu-c topology, exhibiting efficient gas adsorption and drug delivery capabilities. The material has been shown to exhibit excellent hydrogen and methane adsorption properties.
Researchers developed a new approach to analyze coercivity in soft magnetic materials using machine learning and data science. The method condenses relevant information from microscopic images into a two-dimensional feature space, visualizing the energy landscape of magnetization reversal. This study showcases how materials informatics...
Scientists at Tokyo University of Science developed an 'extended Landau free energy model' to analyze complex interactions in nanomagnetic devices, enabling causal analysis and visualization. The model proposed optimal structures for nano-devices with low power consumption.
The study investigates the degradation of carbon fiber-reinforced ultra-high-temperature ceramic matrix composites at temperatures above 2000°C. The results show that the amount of zirconium in the alloy affects the composite's oxidation resistance, and modifying the matrix composition is necessary to prevent degradation.
Researchers developed a novel intranasal delivery system that utilizes the trigeminal nerve to deliver antidepressant drugs to the brain. The system showed efficacy at delivering the same dose as intracerebroventricular administration, highlighting a potential new approach for treating depression and other neurological disorders.
Researchers from Tokyo University of Science found that chronic social defeat stress (cSDS) induced mice showed higher intestinal transit ratio and visceral pain-related behaviors, similar to IBS. The study suggests that prolonged psychological stress can cause IBS-like symptoms in mice without intestinal lesions.
A recent study by Tokyo University of Science researchers provides theoretical foundations for effective parameter tuning in the Bernoulli shift map. They used modular arithmetic to determine optimal parameter values for preserving chaos, with implications for other chaotic maps like the tent and logistic maps.
Researchers from Tokyo University of Science developed a flexible flow sensor that can measure shear stress and flow angle on curved surfaces. The sensor demonstrated effectiveness in measuring airflow speeds up to 170 m/s and has potential applications in industrial-scale fluid machinery.
A novel oxytocin derivative, PAS-CPPs-oxytocin, has been shown to improve cognitive function in mice with Alzheimer's-like symptoms. The derivative is delivered via intranasal administration and shows increased brain penetration compared to traditional intracerebroventricular delivery.
Researchers have developed a scalable, fully coupled quantum-inspired processor that can solve optimization problems efficiently. The system uses an array calculator approach to divide calculations among multiple chips, reducing data transmission and increasing performance.
Scientists developed a cellulose nanofiber-carbon fiber composite film with excellent in-plane anisotropic thermal conductivity, improving heat dissipation in thin-film devices. The material also exhibits recyclability and can be reused after burning the cellulose matrix.
A new study by Tokyo University of Science researchers reveals that overconfidence in one's ability can lead to a desire for income equality, but with nuances. Participants who experienced a gap between their income and self-evaluated ability were more likely to support reducing income inequality, particularly among left-wing individuals.
Researchers discovered that autophagy facilitates the elimination of cancer cells via cell competition, highlighting its potential as a target for cancer prevention and treatment. The study sheds light on the role of autophagy in maintaining tissue homeostasis and opening avenues for novel anti-cancer therapeutics.
A team of researchers from Japan successfully reconstructed common brain input signals from the firing rates of neurons using a method called superposed recurrence plot. This breakthrough has significant implications for artificial intelligence, neuroscience, and potential treatments for mental health disorders.
A new study analyzing baby names from municipality newsletters found rising trends of individualism in Japan, with unique names increasing from the 1980s to 2018. The research suggests a cultural shift towards greater uniqueness and independence.
A new study proposes a method of foam stabilization that could be used to make highly efficient hand sanitizers. The team added an anionic surfactant, long-chain alcohols, and an inorganic electrolyte to an aqueous solution containing 60% ethanol by volume.
A team of Japanese researchers used reinforcement learning to study fluid mixing during laminar flow, achieving exponentially fast mixing without prior knowledge. The method also enabled effective transfer learning, reducing training time for new mixing problems, and has potential applications across various industries.
Scientists have elucidated the regulatory functions of Pan1p, a key player in late-stage clathrin-mediated endocytosis. The protein drives actin assembly and disassembly, facilitating vesicle internalization.
Researchers from Tokyo University of Science develop a method to determine the number of samples required for accurate assessment of microplastic contamination in urban rivers. The study found that at high MP concentrations, two replicate samples are sufficient to measure MP concentrations accurately.
A research group from Tokyo University of Science has discovered molecular features that govern the filling process at nanoscales, enabling finer resolutions in ultraviolet nanoimprint lithography. The findings provide valuable insights for guiding the selection and design of optimized resists for sub-10 nm resolution.
Researchers from Tokyo University of Science create a metal–organic framework-based magnesium ion conductor showing superionic conductivity at room temperature, overcoming the limitations of magnesium ion-based energy devices. The novel Mg2+ electrolyte exhibits a high conductivity of 10−3 S cm−1, making it suitable for battery applica...
A new study by Tokyo University of Science researchers reveals that dendritic cell immunoreceptor (DCIR) plays a crucial role in the development of colorectal tumors. Blocking DCIR may prevent ulcerative colitis and colon cancer, offering a potential therapeutic target for treating these diseases.
A study published in NeuroReport reveals that ultrasound exposure improves depressive behavior in a rat model of depression. OB rats exposed to USV had significantly lower hyperemotionality scores and plasma corticosterone levels than unexposed rats, suggesting potential anti-depressant effects.
Researchers from Tokyo University of Science found that short PPG signals can be used to estimate dynamical properties like determinism, predictability, and complexity with good accuracy. However, shorter signals may not be sufficient for estimating divergence.
A Japanese study reveals that policy disagreement and politicization led to the split of Japan's largest opposition party in 2017. The researchers found that traditional DIF analysis failed to capture the complexity of party positions, but a corrected version showed strong discord over defense policy.
A new study led by Tokyo University of Science researchers identifies altered gene expression and cell function changes that drive DNA damage and neoplasia in cholangiocytes exposed to 1,2-dichloropropane. The findings highlight the importance of macrophage involvement in carcinogenesis.
Researchers from Tokyo University of Science create new method for producing heterolayer coordination nanosheets with improved properties and controllability. The study expands the diversity of 2D materials, enabling potential applications in optoelectronics and renewable energy.
A team of researchers from Tokyo University of Science has developed a novel multi-proton carrier complex that shows efficient proton conductivity even at high temperatures. The resulting starburst-type metal complex acts as a proton transmitter, making it 6 times more potent than individual imidazole molecules.