Scientists at Tokyo University of Science discovered endophytic bacteria that can survive extreme conditions within passion fruit seeds. The bacteria were isolated from seedlings grown from cut seeds and found to possess biocatalytic activities related to the metabolism of secondary metabolites, such as resveratrol and piceatannol.
Scientists at Tokyo University of Science develop a new methodology to investigate the elusive electric double layer (EDL) effect in all-solid-state batteries. The study reveals that the EDL effect is dominated by the electrolyte's composition and can be suppressed through charge compensation, leading to improved performance.
Researchers from Tokyo University of Science developed a self-powered diaper sensor that monitors urine sugar levels, providing an alternative biomarker for blood sugar monitoring. The sensor uses a biofuel cell powered by glucose in the urine, detecting sugar levels within 1 second and simplifying caretaking tasks.
A team of researchers at Tokyo University of Science has developed a stable and highly active photocatalyst from gold nanoclusters. By removing the protective molecules around the nanoclusters, they were able to increase their catalytic activity and stability, opening up new possibilities for hydrogen generation and other applications.
Scientists have developed a new way for head-worn electronics to communicate with each other, safely transmitting signals through the human body. The study uses binaural hearing aids, which improve sound localization and intelligibility by adapting to the sound field.
Researchers found significant periodic flow velocity fluctuations in fuel injector ignite combustion oscillations, leading to high mechanical stress on the combustion chamber. The findings provide a reasonable answer for why these oscillations occur and have significant implications for preventing fatal damage in critical engines.
A Tokyo University of Science researcher analyzed 8,000 infant names and found that common boys' name "大翔" has at least 18 readings, while girls' name "結愛" has at least 14. The study shows that parents use various readings, including non-existent ones, and abbreviate common readings.
Scientists at Tokyo University of Science developed a copper-containing polymer that greatly enhances the antibacterial activity of hydrogen peroxide. The use of these tailored polymers resulted in higher catalytic activity and more effective killing of bacteria, opening up new design avenues for antimicrobial drugs.
Researchers have developed a self-powered, UV photodetector using coordination nanosheets that demonstrate exceptional photocurrent stability under air exposure. The device, composed of an iron ion bonded to a benzene hexathiol molecule, retains over 94% of its photocurrent after 60 days.
A team of scientists from Tokyo University of Science identified mefloquine as an effective drug against SARS-CoV-2. The study found that mefloquine reduced viral RNA levels when applied at the viral entry phase, and showed greater anti-viral activity in combination with Nelfinavir.
A novel drug candidate, KNT-127, has been developed to target glutamate-induced neurotransmission and reduce anxiety-like behavior in mice. The study proposes a new mechanism of action for treating anxiety disorder, which could lead to the development of evidence-based antipsychotics with a new mechanism.
A study by Prof. Gaku Ichihara's team found that Nrf2 increases the expression of protective genes in response to acrylamide toxicity, reducing neurotoxic effects and inflammation. The research provides valuable insights into the mechanisms of immune response to acrylamide-induced toxicity.
Researchers at Tokyo University of Science found a promising treatment for COVID-19 using the drugs cepharanthine and nelfinavir, which show potential in suppressing SARS-CoV-2. Computational models predict combined therapy could hasten clearance of the virus from patients' lungs.
A study by Tokyo University of Science researchers analyzed the relationship between economic growth and environmental preservation. The model indicates that achieving a 'zero-emission society' is compatible with economic growth, but only if GDP is above a certain level and pollution reduction allocation is flexible.
Insect larvae partner with bacteria to shut down plant defense mechanisms, allowing them to consume crops. Researchers discovered the role of Staphylococcus epidermidis in this process and its implications for crop protection.
A new design method for optimizing fiber orientation and thickness simultaneously reduces the weight of carbon fiber reinforced plastics by more than 5% while maintaining its strength. The approach, developed by researchers at Tokyo University of Science, enables higher load transfer efficiency compared to traditional methods.
A genetic mutation associated with autism can inhibit the release of oxytocin, a peptide that regulates social behavior, and cause abnormal social behavior in mice. This finding suggests that CAPS2 protein plays a critical role in facilitating the release of peripheral oxytocin into the bloodstream.
A novel screening strategy using cultured plant cells can identify microorganisms that stimulate plant immune mechanisms without harming plants. Eight bacterial strains were found to boost cryptogein-induced ROS production, inducing whole-plant resistance to bacterial pathogens.
A new algorithm corrects motion blur in single-photon images, allowing for high-quality pictures even with multiple objects moving independently. The approach accurately estimates individual object motion and groups pixels by similar motion, enabling deblurring of each region independently.
A researcher at Tokyo University of Science discovered a menthol-like compound that enhances plant defense against pests. The compound, valine menthyl ester (ment-Val), can be used as an alternative to chemical pesticides and has shown promise in reducing pest damage to various crops.
Researchers found that drones were only slightly less expensive per unit area than tractor-mounted boom sprayers for pest-control costs, while also having a slight advantage in daily area coverage. Data envelopment analysis showed that both boom sprayers and UAVs reached maximum or near-maximum efficiency for most paddy areas.
Scientists at Tokyo University of Science develop biofuel cells that use lactate to generate power for wearable devices. The new design can drive a commercially available activity meter for 1.5 hours using one drop of artificial sweat.
Scientists have developed novel multi-stimuli-responsive drug delivery systems using hydrogels that can release drugs in response to temperature, pH, and reducing conditions. The hydrogels can control the amount of drug loaded onto them, ensuring effective delivery to target tumor sites.
Researchers at Tokyo University of Science have developed a new method to quantify fat content in liver tissue using near-infrared hyperspectral imaging. The study found that this technique can accurately visualize lipid distributions within the liver and identify fatty liver-associated liver diseases, including cancer.
Researchers identified genes overexpressed in mouse models of arthritis, showing that TARM1 suppresses immune system response and collagen-induced arthritis. TARM1 inhibition weakens autoimmune arthritis, suggesting a new treatment target for autoimmune diseases.
Scientists discovered the structural and molecular factors governing the stability of a protein complex involved in DNA repair pathways. The study reveals that exposure to organic solvents and oxidizing environments can cause the complex to disassemble, offering insights into novel phenomena and potential treatments for diseases such a...
Researchers identified a mechanism linking acrolein accumulation to glycocalyx modifications, damaging the blood-brain barrier. The study suggests that acrolein-modified proHPSE could be a novel drug target for post-stroke inflammation.
Scientists have developed a wearable microfluidic sensor to measure lactate concentration in sweat, offering real-time insights into muscle condition during exercise. The device is designed for comfort and practicality, using a non-irritating material and a microfluidic system for sweat collection.
Plants have evolved a defense system to warn themselves of predator attacks and ward off damage. Elicitors, such as molecular patterns and saliva proteins, trigger an 'SOS signal', initiating defense responses.
Researchers discovered a unique step-terrace-like surface structure in quasicrystal-like materials, which depends on the biasing voltage applied to the sample. The study, led by Prof. Ryuji Tamura from Tokyo University of Science, offers exciting possibilities for material scientists to explore.
Researchers have developed a technology that uses near-infrared hyperspectral imaging (NIR-HSI) along with machine learning to visualize tumors in deep tissue and covered by a mucosal layer. The technique was tested on 12 patients with confirmed cases of gastrointestinal stromal tumors (GISTs), achieving an accuracy of 86% in identifyi...
Researchers at Tokyo University of Science explore the structure of porphyrin derivatives to selectively target cancer cells and improve drug delivery. They found that meso-derivatives accumulate in cells at 3-fold higher amounts than β-derivatives, and that smaller functional groups allow better aggregation.
Researchers from Tokyo University of Science modified mesenchymal stem cells to carry anti-cancer drugs and deliver them to target cancers, showing efficient delivery in mouse models. The study suggests a faster and more effective method for delivering drugs to tumor cells.
Researchers at Tokyo University of Science devise a new electrochemical technology to manufacture ammonia-based fertilizer from urea, addressing the problem of food production in closed environments. The study aims to provide a solid basis for sustaining long-term stay in extremely closed spaces such as space stations.
A new carbon-based material for sodium-ion batteries has been developed with a capacity of 478 mAh/g, exceeding that of graphite used in lithium-ion batteries. The material's lower temperature heat treatment reduces energy expenditure and environmental impact.
Researchers at Tokyo University of Science developed a strategy to identify criminals from a single strand of hair, leveraging the composition of hair dye products. They employed surface-enhanced Raman spectroscopy (SERS) and X-ray fluorescence (XRF) analysis to distinguish between different dyes applied to individual strands of hog hair.
Researchers explored oxidation mechanisms in Yb-Si coatings at high temperatures under different atmospheres. The study found that the Yb to Si ratio affects oxidation behavior and that ytterbium content can suppress SiO2 growth, leading to more heat-resistant coatings.
A team of scientists at Tokyo University of Science has developed a novel synthesis method to create phenazinones, which show high cytotoxicity towards cancer cells. This breakthrough could lead to the creation of new anticancer drugs with minimal side effects.
Researchers have developed an all-solid redox transistor containing a thin film of Fe3O4 on magnesium oxide and lithium silicate electrolyte, enabling reversible rotation of the magnetization angle in magnetite at room temperature. The device operates with lower power consumption than traditional spin current injection methods.
Researchers from Tokyo University of Science developed a novel strategy to predict the lifetime of replica molds used in UV-NIL by analyzing changes in the contact angle of water on the mold surface. The method uses commercial camera-based systems and can accurately predict when a mold will break, reducing costs associated with UV-NIL.
Researchers at Tokyo University of Science create a novel strategy to produce moth-eye nanostructures and transparent films, overcoming previous scalability issues. The resulting film exhibits remarkable optical properties, including low reflectance and increased transmittance.
Researchers at Tokyo University of Science create a novel approach to reducing chromium toxicity in wastewater through the chemical reaction of reduction, employing photocatalysts like titanium oxide and copper complexes. The method has high efficiency and is reusable, providing a promising technology for environmental regulation.
Researchers from Tokyo University of Science found that Sb atoms introduce a slight distortion in the interatomic distances, promoting phonon scattering and increasing thermal conductivity. This leads to improved electrical conductivity and thermoelectric performance of doped Mg2Si.
Researchers from Tokyo University of Science design a new quantum circuit that calculates the fast Fourier transform, a key algorithm in engineering. The QFFT circuit exploits superposition of states to greatly increase computational speed and is more versatile than traditional QFT.
Researchers from Tokyo University of Science developed a novel methodology for early detection of flutter in turbine blades. Before the onset of catastrophic 'flutter,' one blade acts as a central hub, triggering synchronization among adjacent blades. This study contributes to safer and more eco-friendly turbine designs.
Scientists from Tokyo University of Science have discovered a natural food pigment Monascus purpureus that can distinguish between living and dead cells. The pigment is robust against chemotherapy drugs and does not damage living cells, making it a promising tool for screening cell viability in various types of cancer research.
A study by Tokyo University of Science researchers found that self-esteem increases with age in Japan, peaking in the 50s and 60s, unlike previous research in Europe and the US. The findings suggest that cultural factors such as the seniority system and respect for the aged may contribute to this difference.
Researchers at Tokyo University of Science have identified a polyphenolic compound called pterostilbene with strong immunosuppressive properties, making it a promising anti-inflammatory agent for treating inflammatory bowel disease and other disorders. The study found that the compound prevents T cells from differentiating into pro-inf...
A recent study suggests that giant viruses, such as medusavirus, may hold the key to understanding the evolutionary origins of the eukaryotic nucleus. The virus's ability to occupy and use the host nucleus for replication provides evidence for lateral gene transfer between ancient proto-eukaryotic cells and giant viruses.
Researchers at Tokyo University of Science develop novel mechanism for tuning luminescence of a transparent material by controlling proton concentration via voltage application. This breakthrough discovery opens possibilities for advancing methodologies in biological and electronics research.