A comprehensive review suggests COVID-19 infects both upper and lower respiratory tracts, causing a uniquely aggressive immune response that leads to severe health issues months after infection. This dysregulation of the immune response contributes to long-COVID and severe lung damage in some individuals.
Researchers at Trinity College Dublin developed a magnetic material that demonstrates the fastest magnetic switching ever recorded, six times faster than the previous record. The discovery could lead to new energy-efficient ultra-fast computers and data storage systems, revolutionizing the field of information technology.
Researchers at Trinity College Dublin have developed a new graphene-based sensing technology using G-Putty material, which is 50 times more sensitive than industry standards. The technology has the potential to transform wearable electronics and medical diagnostic devices, offering tailored sensors for various applications.
Researchers detected a new chemical signature, hydroxyl radical (OH), on the dayside of WASP-33b, an ultra-hot Jupiter. The discovery provides insight into the chemistry of exoplanet atmospheres and could help search for 'Earth-like' planets.
Scientists from Trinity College Dublin found that skeletal defects caused by lack of movement in the womb can be partially recovered after movement resumes. The study used chicken embryos and suggests that this finding may also apply to humans.
New research reveals fundamental differences in how baby and adult immune cells respond to TB, with a greater ability of adult cells to shift their energy profile after infection. The study highlights the importance of understanding how the immune system uses energy to develop better treatments for vulnerable populations.
New research from Trinity College Dublin suggests a correlation between increasing Sika deer populations and higher local bovine TB infections in Ireland. The study found that County Wicklow is a hotspot for both Sika deer and TB infections.
A new approach to genetic comparisons resolves a debate on the most distant animal relative. Sponges are identified as our closest relatives due to improved analyses and reduced errors in previous studies.
Researchers found that adding an iron binder to Bedaquiline treatment boosts its ability to combat TB bacteria. The study suggests a promising approach to improving patient outcomes and developing new treatments.
The study found that dry ice sublimation can form unique radial systems on Mars' surface, similar to spiders. The experiments showed that the Leidenfrost Effect plays a crucial role in eroding the spider patterns, which were more branched with finer grain sizes.
Researchers describe unprecedented level of detail on Sierra Negra's eruption, shedding light on volcano behavior and predicting future hazards. The study combines data from instruments and chemical analysis to better understand caldera resurgence and earthquake triggers.
Scientists have discovered that the high silica content in ancient rocks formed in the Earth's mantle is linked to a significant change in the planet's interior around 2.5 billion years ago. This boundary may have been caused by changes in the mantle's flow, leading to the loss of extremely high temperatures.
An international team of researchers solved a puzzling phenomenon involving vortex-like structures in the Cold Spray deposition process. The discovery, published in Materials & Design, reveals that these structures form when the CS process has low deposition efficiency, leading to improved adhesion between coatings and substrates.
A study published in Psychology and Aging suggests that older adults exhibit lower mind-wandering frequency and perform better on cognitive tasks due to increased motivation. This is attributed to their ability to reduce anxiety and improve focus, which enables them to mitigate potential costs associated with mind-wandering.
A new strategy has been developed to fast and reliably quantify the immune response induced by vaccination, revealing the timeline and stage of pathogen infection. The technique is equally sensitive to existing gold-standard methods and can detect multiple target molecules in a fraction of the time.
Researchers have discovered how Staphylococcus aureus binds to human corneocytes in atopic dermatitis, providing new insights into the development of targeted treatments.
A team of scientists explores the feasibility of achieving 100% renewability in energy production, highlighting the need for electrification and synthetic fuel technology. The study suggests that countries like Argentina, Cyprus, Greece, Portugal, and Spain could meet their energy needs with high-tech renewably derived fuels.
Researchers at Trinity College Dublin identify genetic mutations linked to ultra-rare condition ALSP, revealing that dysfunctional white blood cells drive brain damage and BBB breakdown. The study's findings may pave the way for targeted therapies for other forms of dementia.
Researchers at Trinity College Dublin have identified a new mechanism for the formation of bastnèsite, a rare earth-bearing mineral essential for low-carbon energy generation and smart devices. The discovery has important economic implications due to the high demand for rare earth elements and their limited availability.
Scientists from Trinity College Dublin have developed a new gene therapy approach that successfully protected the visual function of mice with dysfunctional mitochondria. The treatment also improved mitochondrial performance in human cells with OPA1 gene mutations, offering hope for treating diseases like Alzheimer's and Parkinson's.
Researchers found previously unknown changes in brain networks after polio and neurological diseases like MND/ALS, suggesting abnormal communication between muscles and brain. The study increases understanding of brain plasticity and its implications for rehabilitation and new biomarker development.
A study published in Ecological Indicators found that acoustic surveys in Okinawa, Japan are hindered by the loud cicadas, masking the sounds of native animals. This highlights the need to consider ambient conditions when using this technique for biodiversity assessment.
Researchers have pinpointed two new potential therapeutic targets for rheumatoid arthritis, a painful inflammatory disease affecting millions worldwide. The study reveals a novel cell population and mechanism driving joint inflammation, offering new avenues for therapy development.
A multidisciplinary team will assess the significance of marine life to human societies during the last two millennia. The 4-OCEANS project aims to understand the consequences of marine resource exploitation for societal development, with a focus on informing the UN's Sustainable Development Goals and the Decade for the Oceans.
A new study reveals high levels of microplastics are released from infant-feeding bottles when preparing formula, with warmer liquids leading to greater MP release. The researchers developed recommendations to minimize MP release, calling on policymakers to reassess current guidelines for safer bottle use.
The researchers found that even in ideal conditions, quantum superposition leads to rare events with higher heat dissipation than the Landauer limit, which challenges traditional understanding of information erasure. This finding has significant implications for future quantum chips and thermodynamics.
Researchers found that athletes feel isolated and excluded when injured, hiding their pain and injury due to pressure to perform. The study aims to create a sporting environment prioritizing physical health and welfare, with tailored injury management programs and athlete-centered care.
Researchers from Trinity College Dublin found that male and female Sulawesi Babblers have evolved to attain different sizes on small islands, reducing competition by feeding on scarce resources. This discovery provides new insights into the importance of sexual dimorphism in island ecosystems.
A new material has been found to enable ultra-fast toggle switching, which could increase the capacity of fibre optic cable networks by an order of magnitude. This breakthrough overcomes three major obstacles to further progress with the internet: speed, energy consumption, and network capacity.
Researchers developed a novel thermometer based on quantum entanglement that can accurately measure ultra-cold temperatures in clouds of atoms, known as Fermi gases. The new method uses a probe atom to infer temperature by exploiting the unique properties of fermions at extremely low temperatures.
Dr. Tomás Ryan has received a highly prestigious award from the Lister Institute of Preventive Medicine to pursue research into infantile amnesia and its effects on learning. The prize will support his work on understanding the neurobiology of memory loss in early childhood.
Researchers found that reducing caesarean section rates among first-time mothers can result in substantial economic savings, with net present values of €1.1million and £9.8million per annual cohort. Improving vaginal births after c-sections also yields significant benefits, with net present values of €3.5M and £23.0M per annual cohort.
Researchers discovered chemically diverse magmas beneath Galapagos volcanoes, which could become mobile and lead to unexpected explosive eruptions. The findings challenge the long-held assumption that volcanoes producing consistent basaltic lava flows are stable.
Scientists at Trinity College Dublin discovered a way to manipulate human immune responses to Mycobacterium tuberculosis, tipping the balance in favor of patients. The study used an epigenetic inhibitor to release pro-inflammatory signals that aid in clearing the infection, promoting future vaccine strategies.
A joint report from Trinity College researchers and ALONE highlights increased feelings of loneliness, anxiety, and isolation in older adults during the COVID-19 pandemic. Most callers to ALONE's national support line were from over-70s living alone, reporting negative emotions and putting off medical treatment.
Researchers from Trinity College Dublin have discovered a new link between impaired brain energy metabolism and delirium, a disorienting disorder common in the elderly. Collectively, their research suggests that therapies focusing on brain energy metabolism may offer new routes to mitigating delirium.
Researchers at Trinity College Dublin have developed a novel device that enables controlled single photon emission from quantum dots, a crucial component in quantum computing and communications. This breakthrough allows for entangled states of pairs of quantum dots, paving the way for significant advancements in quantum technologies.
A genome analysis of an adult male from Newgrange passage tomb suggests he was part of a ruling social elite practicing first-degree incest. This practice is rare in human societies, typically found among elites with deified royal families.
A new Irish study challenges claims that high blood levels of folate increase the risk of poor cognition in older adults. The study found no evidence of adverse effects, while higher folate levels were associated with better cognitive function in older adults.
Scientists have developed a new gene therapy approach that offers tremendous promise for treating an eye disease that leads to blindness. The collaborative team used a modified virus to deliver a normal functioning copy of the RP2 gene into 'mini retinas' containing the defective version, resulting in significant improvement.
A study published in Epilepsia journal found that 8% of individuals with a history of seizures report hallucinations, which are associated with a higher risk of mental health disorders and suicidal behavior. The study highlights the importance of assessing hallucinations in epilepsy clinics to identify high-risk patients.
The new app, called neureka, uses brain games and self-reflection challenges to collect data on mental health and dementia research. It aims to identify modifiable risk factors for disorders of the mind and capture complex datasets to develop individualized understanding of brain health.
A new study by Trinity College Dublin reveals that a diverse range of trees and shrubs in West African parkland habitats supports fruit production and pollination services, ultimately benefiting the shea crop and local communities. The findings have important implications for managing this critical crop and conserving pollinators.
Scientists at Trinity College Dublin have discovered that the iron chelator DFX supports lung immunity against tuberculosis by driving the activation of glycolysis, a key metabolic pathway. This process helps immune cells make energy to fight infection and improves macrophages' ability to address TB infection.
A multi-disciplinary team has identified a protein called SARM1 as a potential therapeutic target for treating retinal degeneration. This discovery may provide a new approach to slowing the progression of blinding diseases such as AMD and retinitis pigmentosa.
Researchers have identified a rare immune cell type that expresses both alpha-beta and gamma-delta T-cell receptors, which can both protect against infection and trigger autoimmune responses.
A breakthrough discovery by Trinity College Dublin researchers identifies Caspase-11 as a key driver of allergic inflammation in asthma. This finding holds great promise for developing new therapeutic options to treat the debilitating disease.
New preclinical research suggests that targeting overactive immune cells can improve traumatic brain injury recovery and modulate chronic neurotoxic effects. The study found that a therapeutic strategy to inhibit microglia cells after TBI led to better motor and cognitive performance in mice.
Scientists from Trinity College Dublin have discovered that TLR2 plays a critical role in the development of retinal degeneration, a leading cause of blindness. The study suggests that regulating TLR2 activity may help prevent dry AMD, offering new avenues for therapy.
Researchers found that around one-third of orphan genes result from divergence, suggesting de novo emergence is more frequent than thought. Emerging genes carry potential to be important, as artificially expressed sequences showed increased growth rates in baker's yeast cells.