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Trinity College Dublin


Geneticists discover hidden “whole genome duplication” that may explain why some species survived mass extinctions

Researchers have pinpointed a previously hidden whole genome duplication in the common ancestor of sturgeons and paddlefish, which may have provided genetic variations that helped these species survive mass extinctions. The discovery suggests that there may be many more overlooked whole genome duplications in other species before perio...

SourceTrinity College Dublin·JournalNature Communications·TypeExperimental study·DateMay 31, 2023

“We were dancing around the lab” – cellular identity discovery has potential to impact cancer treatments

Researchers at Trinity College Dublin have discovered a new process that explains why cells have unique identities. By studying Polycomb protein complexes, the team found that different forms of these proteins recruit distinct complexes to DNA, shedding light on cellular identity and its potential impact on cancer treatments.

SourceTrinity College Dublin·JournalMolecular Cell·DateApr 7, 2023

Trinity and University of Manchester researchers tackle parasitic worms that infect millions worldwide

A recent study published in the journal Immunity has shed light on the immune response to parasitic worm infection, revealing a critical role for T cells and macrophages. The research team identified specific signaling molecules that control the development of tissue-resident macrophages, which are essential for eliminating the infection.

SourceTrinity College Dublin·JournalImmunity·TypeExperimental study·DateMar 30, 2023

Fresh understanding of ageing in the brain offers hope for treating neurological diseases

Researchers have found a possible new target for therapies aimed at treating age-related neurological diseases by linking increased presence of immune cells to conditions like Alzheimer's disease. Microglia, specialized immune cells in the brain, can adopt a dysfunctional state that contributes to neurodegenerative diseases.

SourceTrinity College Dublin·JournalScience Advances·TypeExperimental study·DateMar 8, 2023

Separation leads to significant but temporary gender differences in parent-child time

A study by sociologists from Trinity College Dublin and UNED Madrid found that parental separation results in significant but temporary increases in gender inequalities in parent-child time. After separation, mother-child time doubles while two-parent time declines threefold, with father-child time remaining low.

SourceTrinity College Dublin·JournalEuropean Journal of Population / Revue européenne de Démographie·TypeSurvey·DateJan 17, 2023

Financial strain and material deprivation linked to increased child behavioural difficulties More nuanced measures of economic hardship required to help address cost-of-living crisis and its effects on children

A new study by researchers at Trinity College Dublin found that financial strain and material deprivation are associated with higher child behavioral difficulties. The study suggests that more nuanced measures of economic hardship are required to accurately understand the effects of economic hardship on households and their children.

SourceTrinity College Dublin·JournalJournal of Youth and Adolescence·TypeCase study·DateJan 13, 2023

Ancient amphibians had their bones cooked

Scientists have solved a decades-long puzzle about why ancient tetrapod fossils in Ireland's Jarrow Assemblage had their internal bone structure altered. The team used CT scans and laser ablation to analyze the chemistry of the bones, finding evidence of superheated fluids that cooked and melted the bones.

SourceTrinity College Dublin·JournalPalaeontology·TypeExperimental study·DateDec 7, 2022

Why silly distractions at work can actually be good for you

A new study from Trinity College Dublin and WHU – Otto Beisheim School of Management found that brief positive interventions, such as watching a funny video, can help employees overcome daily challenges like annoying emails or unloved tasks. This leads to increased effectiveness at work, including better engagement, creativity, and beh...

SourceTrinity College Dublin·JournalWork & Stress·TypeSurvey·DateNov 28, 2022

Promising results from psilocybin trial for treatment-resistant depression

Researchers conducted the largest clinical trial to date of psilocybin, finding a statistically significant rapid reduction in symptoms of depression. The study suggests that COMP360 psilocybin with psychological support could be an effective treatment strategy for people with treatment-resistant depression.

SourceTrinity College Dublin·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateNov 7, 2022

Fishing for sharks: Hot or not?

New research reveals that shark fishing can cause rapid temperature spikes in caught and released sharks, with one blue shark experiencing a 2.7°C increase in just minutes. The study found that it took up to 40 minutes for the sharks to cool down after release.

SourceTrinity College Dublin·JournalConservation Physiology·TypeExperimental study·DateOct 5, 2022

Water flouridation: Effective prevention for tooth decay and a win for the environment - Trinity research

A new study by Trinity College Dublin researchers shows that water fluoridation has the lowest environmental impact among community-level caries prevention programmes, offering a sustainable solution to prevent dental decay. The study also highlights its cost-effectiveness and ability to reduce disability-adjusted life years.

SourceTrinity College Dublin·JournalBDJ·TypeData/statistical analysis·DateAug 29, 2022

Reduction in brain tissue oxygenation placing older adults with multiple health conditions at risk of faints and falls

A study of 350 older adults found that those with multiple chronic health conditions, especially women, are more prone to large blood pressure drops and lower brain oxygenation after standing up. This increases their risk of dizziness, faints, and falls, highlighting the importance of detecting and managing multi-morbidity.

SourceTrinity College Dublin·JournalJournal of the American Geriatrics Society·TypeExperimental study·DateAug 18, 2022