Researchers used human pluripotent stem cells to model early placental formation, discovering VGLL1 plays a crucial role in turning stem cells into placental stem cells. The study's findings could lead to improved embryo quality and viability, especially for in vitro fertilization.
A new study from UC San Diego finds that adults who experienced intimate partner violence are more likely to own firearms and purchase them recently. The analysis of statewide survey data suggests a strong association between experiencing or perpetrating intimate partner violence and increased firearm ownership rates.
Researchers at University of California San Diego School of Medicine found that streamlined surgical preference cards can significantly reduce hospital waste and improve operational efficiency. By analyzing thousands of surgeries, they identified unnecessary items and optimized lists to save up to $3 million over five months.
A genetic study of 135,000 participants revealed 11 genetic regions tied to delayed gratification, showing overlap with risks for conditions like obesity and diabetes. The study found that delay discounting is deeply intertwined with genetic pathways involved in brain development, cognition, and physical health.
The coralME tool creates detailed genome-scale models of metabolism, gene and protein expression from large amounts of data. The models uncover how microbes respond to certain nutrients and predict what nutrients favor the formation of undesired products.
The Herbert Wertheim School of Public Health and Human Longevity Science at University of California San Diego is expanding its roadway safety education efforts to reach more Californians, with a focus on Native American youth, pedestrian safety and Spanish-speaking communities. The project will train local Native peer educators to del...
Researchers at UC San Diego found that cancer cells use non-genetic mechanisms to regrow after targeted therapy, which could help prevent tumor recurrence. By blocking these signaling pathways, future treatments may be able to stop tumors from relapsing during therapy.
Researchers at UC San Diego have developed a new method to combat antibiotic-resistant bacteria using bacteriophages, which target the Klebsiella pneumoniae species. The evolved phages demonstrated improved effectiveness in killing multiple bacterial strains, including multidrug-resistant and extensively drug-resistant K. pneumoniae.
Engineers at UC San Diego developed a wearable system that enables people to control machines using everyday gestures even in highly dynamic environments. The system combines stretchable electronics and AI to overcome the limitation of gesture signals falling apart under excessive motion noise.
Most San Diego County beaches grew in width last year during the post-El Niño recovery phase. California's average beach width has remained stable across nearly four decades despite notable examples of beach erosion. Beach nourishment projects also contributed to recent increases in beach width.
Researchers at UC San Diego School of Medicine have identified a promising new therapy for triple-negative breast cancer (TNBC), employing an antibody-drug conjugate to deliver chemotherapy directly into cancer cells. Targeting tumor-initiating cells through FZD7 may offer a path forward for patients with aggressive TNBC that fails to ...
A recent study found that Google searches for lorazepam increased by 1.6 million over a 12-week period during the airing of The White Lotus, compared to normal expectations. The show's portrayal of lorazepam use was associated with this surge in interest, including queries on how to acquire it online.
A recent study published in Cancer Investigation found that GLP-1 receptor agonists significantly reduced the risk of death among colon cancer patients. The analysis of over 6,800 patients revealed a nearly 50% lower likelihood of death within five years compared to non-users.
Researchers developed a new approach combining genetic ancestry, lifestyle, and social determinants of health to identify individuals with skin cancer. The AI model achieved 89% accuracy in identifying skin cancer across all populations, with 90% accuracy for European ancestry and 81% accuracy for non-European ancestry.
Researchers at the University of California San Diego have developed an electronic sticker that monitors vitamin C levels using sweat from fingertips, providing a convenient and low-cost alternative to current methods. The system is battery-free and can be manufactured at a low cost, making it potentially disposable and widely accessible.
A new alloy design strategy for metal alloy negative electrodes has improved the performance and durability of next-generation solid-state batteries. The design enhances lithium ion movement, leading to faster charge-discharge rates and longer battery lifespan.
Researchers found that a one-week meditation retreat produced rapid changes in brain function, metabolism, immunity, and pain relief. The study suggests that intensive meditation can trigger similar brain activity to psychedelic substances, promoting mental health, emotional regulation, and stress resilience.
A recent University of California San Diego-led study shows that understanding the origin of rainfall is crucial in reshaping drought planning and land management. The research reveals that regions with high reliance on land-sourced moisture are more vulnerable to drought, soil moisture loss, and yield declines.
A study found that undergraduate computer science students initially increase their trust in generative AI programming tools, but long-term trust remains unclear. To address this, researchers recommend that educators provide tasks-based training and ensure students comprehend and modify code without relying on AI assistants.
A team of scientists has successfully developed a new method for producing large amounts of xanthommatin pigment in the lab, using a nature-inspired approach. This breakthrough could lead to the creation of camouflage-inspired materials and cosmetics, as well as alternative materials for industries moving away from fossil fuels.
Researchers at the University of California San Diego found that oscillators operating at similar frequencies lock onto each other in succession, creating a staircase effect in the gut. This new mathematical solution answers two longstanding biological questions, shedding light on how food moves through the digestive tract and is churned.
A new study from UC San Diego found that clinical pharmacists can play a crucial role in helping people with cancer and diabetes better manage their blood sugar. The study showed that patients referred to a diabetes management and education clinic led by pharmacists saw meaningful improvements in blood sugar levels over time.
Researchers have discovered detailed visualizations of mosquito's carbon dioxide-detecting neurons, revealing anatomical adaptations designed to target human blood. The study provides key insights into the mosquito's sensing mechanisms and their unique ability to detect CO2, which contributes to their deadly status.
Researchers at University of California San Diego School of Medicine have harnessed bioinformatics to identify Thiorphan as a promising new drug for spinal cord injury, showing effectiveness in adult human brain cells and improving hand function in rats with SCI.
A team from University of California San Diego and Rensselaer Polytechnic Institute invented a scalable technology for faster and more reliable 5G and 6G wireless communication. The technique, dubbed FlexLink, nearly doubles spectrum efficiency and reduces latency.
A new study reveals that different prey within a single species can provide vastly different levels of nutrition for marine predators. This variation can lead to predators consuming more prey than necessary, highlighting the importance of understanding prey quality in maintaining ecosystem balance.
Researchers at UC San Diego School of Medicine developed an AI-powered approach to decode macrophage gene expression patterns. They identified a 53-gene signature that separates reactive from tissue-healing macrophages, resolving a longstanding debate in Crohn's disease.
Researchers developed a generative AI model, BIGE, to generate optimal motions for athletes to avoid injuries and aid in rehabilitation. The model can produce realistic videos of motions that athletes can mimic during training or execute while injured.
Researchers at UC San Diego have discovered a new way to make yeast cells more efficient 'cell factories' for producing valuable plant compounds. The advance enables the sustainable manufacturing of plant-derived chemicals used to help plants defend against disease, repel pests, attract pollinators, and withstand environmental stresses.
A study published in Tobacco Control found that teenagers and young adults who use cannabis are more likely to become regular tobacco users, even if they haven't previously tried tobacco. The study estimated that 13% of new regular tobacco use is attributable to cannabis, with significant implications for tobacco control programs.
A new study by UC San Diego found that a third of Californians use cannabis regularly, yet there are significant gaps in knowledge about driving-related laws and regulations. The researchers emphasize the need for targeted education initiatives to address these knowledge gaps and promote safe driving practices.
The UC San Diego REACH Center for Translational Science on Whole Person Health aims to advance research through partnerships with complementary and integrative health institutions. The center will support at least 26 new research scholars and fund pilot grants to drive innovation in translational science.
A study finds that meltwater from a rapidly retreating glacier in Alaska contained lower concentrations of essential micronutrients like iron and manganese. This could alter the role glaciers play in delivering nutrients to the ocean, with significant implications for marine ecosystems and fisheries.
A new study from UC San Diego's Rady School of Management found that education and social connections play a more significant role in participating in highbrow culture than income. The research used large-scale survey data to compare the UK and US, finding cultural capital dominated in the UK while social capital led in the US.
Researchers at UC San Diego developed a new method for fine-tuning large language models with significantly less data and computing power. This approach updates only the necessary parts of the model, reducing costs and improving generalization.
A team of scientists from Chile and the US discovered dozens of red cusk-eels embedded in tubeworm bushes at a methane seep. The finding suggests these seeps are not just habitats for obscure creatures but also important for commercially fished species like cusk-eels.
Researchers at University of California San Diego have developed an AI-based method to target cancer stem cells, which can spread and resist therapy. The approach leverages machine learning to identify treatment targets and restore function to genes, leading to the self-destruction of cancer cells.
A new study reveals that combining proteasome inhibitors with Lys05 can effectively kill AML cells by disabling backup survival pathways. This approach has shown promise in preclinical models and could lead to improved treatment options for a wider range of AML patients.
A new framework outlines how smarter investments can help cut emissions from the aviation industry. The Aviation Sustainability Index assesses technologies and investments to guide investors towards transformative innovations.
The collaboration aims to deliver high-quality, timely care by leveraging the latest imaging systems and AI tools. This will enable more precise diagnoses with shorter wait times, driving effective treatment across all service lines.
Researchers at University of California San Diego School of Medicine discovered that quorum sensing in S. aureus delays wound healing and found targeting the agr system could disarm bacteria without antibiotics, preserving healthy skin bacteria to enhance recovery.
A new study reveals that ancient hominids were exposed to lead earlier than thought, up to two million years before modern humans began mining the metal. This exposure may have shaped the evolution of hominid brains, limiting language and social development in all but modern humans due to a protective genetic variant.
Researchers developed a soft robotic skin that allows vine robots to navigate convoluted paths and fragile environments. The robot is steered by controlling the pressure inside its body and temperature of the actuators.
A culturally adapted behavioral intervention delivered in Spanish by community health workers significantly reduced unhealthy alcohol use among Latinx adults. Participants showed nearly twice the reduction in heavy drinking days compared to those who received an educational booklet.
A large genetic study found associations between cannabis use and various traits, including psychiatric disorders, cognitive measures, and physical health problems. The study identified two genes, CADM2 and GRM3, linked to lifetime cannabis use and frequency of use.
Researchers developed a new approach to overcome treatment resistance in aggressive cancers by activating macrophages, a type of immune cell abundant in advanced tumors. The custom anti-αvβ3 antibody triggers powerful anti-tumor responses and is highly selective, making it a potentially safer alternative.
Researchers have developed a technology that maps the entire network of RNA-protein interactions inside human cells, offering new strategies for treating diseases like cancer and Alzheimer's. The study uncovered over 350,000 interactions, including many that had never been seen before.
Astronomers detected phosphine in the atmosphere of a cool, ancient brown dwarf named Wolf 1130C using the James Webb Space Telescope. The discovery challenges previous theories and suggests that phosphorus chemistry might be more complex than initially thought.
A recent study at UC San Diego Health found that virtual transition of care clinics lower hospital readmissions for high-risk patients by 14.9%. The clinic provides immediate post-hospital care, reducing no-show rates and improving patient outcomes.
The data release from the HEALthy Brain and Child Development Study offers a detailed look at human brain development in early childhood. The comprehensive data includes information on prenatal health, social and environmental determinants of health, and wearable biosensor data.