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Veterans Affairs Research Communications


Brain-derived compounds show surprising -- and beneficial -- results for cancer in lab studies

A synthetic compound based on a brain hormone has shown surprising benefits in treating lung and other cancers in mice, but its effect on human cells was the opposite. The compound, MR409, is one of several GHRH analogs that spur healthy tissue growth and may alleviate concerns about stimulating cancer cell growth.

SourceVeterans Affairs Research Communications·JournalProceedings of the National Academy of Sciences·DateNov 6, 2018

Think you can handle your alcohol? Study may urge some drinkers to think again

Researchers found that heavy drinkers developed behavioral tolerance to alcohol on simpler fine motor tasks, such as the Grooved Pegboard Test, but not on more complex tasks like the Digit Symbol Substitution Test. Despite faster metabolism, heavy drinkers showed similar levels of impairment on these tasks compared to light drinkers.

SourceVeterans Affairs Research Communications·JournalPsychopharmacology·DateApr 13, 2017

When non-adherence to guidelines is a good thing: Study on COPD yields surprising results

A study on chronic obstructive pulmonary disease (COPD) found that 44% of patients were under-treated, while only 19% received recommended medication regimens. Patients who were under-treated had fewer exacerbations, indicating that ignoring guidelines may be beneficial in certain cases.

SourceVeterans Affairs Research Communications·JournalInternational Journal of Chronic Obstructive Pulmonary Disease·DateJan 20, 2017

Study: Symptoms of 'chronic multisymptom illness' may be common in Iraq, Afghanistan vets

A study of over 300 Iraq and Afghanistan veterans found that nearly 50% met the criteria for mild to moderate CMI, with common symptoms including fatigue, joint pain, and difficulty remembering. The study suggests a link between deployment and CMI, but notes limitations in the research and recommends further investigation.

SourceVeterans Affairs Research Communications·JournalThe Journal of Rehabilitation Research and Development·DateMay 13, 2016

New study reports on suicidal thinking among US veterans

A study of over 2,000 US veterans found nearly 14% reported suicidal thinking at one or both survey phases, challenging past findings that suggest it's a longer-term problem. Social connectedness was linked to remission, while addressing psychiatric and physical health issues may be more critical for those with chronic suicidal thinking.

SourceVeterans Affairs Research Communications·JournalJournal of Affective Disorders·DateApr 5, 2016

Study of 83,000 veterans finds cardiovascular benefits to testosterone replacement

A study of over 83,000 veterans found that restoring normal testosterone levels through gels, patches, or injections reduced the risk of heart attack, stroke, and death. Men who achieved normal levels saw significant benefits in cardiovascular health, while those who did not attained normal levels did not experience similar reductions.

SourceVeterans Affairs Research Communications·JournalEuropean Heart Journal·DateAug 10, 2015