Articles tagged with Covid 19 Vaccines
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Three circulating omicron subvariants have shown improved resistance to vaccine- and infection-generated neutralizing antibodies. BQ.1 and BQ.1.1 are dominating US infections, while BA.2.75.2 is the best at evading neutralizing antibodies.
A new study published in PLOS Medicine found that COVID-19 vaccination provides significant protection against reinfection, with varying levels of effectiveness (60-94%) across different variants. The study analyzed data from over 200,000 people in Denmark and showed that vaccination offered up to 71% protection during the Alpha period...
A large study found that mRNA vaccines increased myocarditis risk in younger males, especially after the second dose. Absolute rates were low, with higher observed rates compared to expected rates.
The study found that COVID-19 vaccination in New York City reduced severe outcomes and avoided substantial economic losses. Every dollar invested yielded estimated savings of $10.19 in health costs.
A study found that NFL fan attendance was associated with increased COVID-19 incidence in the host county and surrounding areas. The findings suggest that large events require extra precautions when vaccines, testing, and countermeasures are not readily available.
Outreach messages via electronic health record patient portals increased well child care visit scheduling and COVID-19 vaccine receipt in a randomized clinical trial of 945 patients. This tool may help restore delayed well child care in populations affected by the pandemic.
Parental COVID-19 vaccination was associated with lower risk of hospitalization in children under 5, supporting widespread vaccination recommendations for young children. The study's results reinforce the importance of parental immunization during high-risk periods.
The FDA's investigation into its own oversight of clinical trials reveals a concerning lack of surveillance, leaving room for scientific misconduct. Experts argue that the agency should inspect sites more frequently to ensure data quality and integrity.
Researchers have developed a new nasal vaccine that induces potent lung immunity and protects against SARS-CoV-2 infection in mice. The vaccine approach, which targets the nose, airways, and lungs, has shown promising results in preventing COVID-19 infection.
A nationwide survey in Germany found that 82% of medical and nursing personnel were vaccinated at least once, with 75% having received two doses. In contrast to the general population, unvaccinated healthcare workers had stronger concerns about vaccine safety and effectiveness. The study suggests a need for targeted measures to convinc...
A new study reveals that COVID-19 causes a significant disruption in vaginal microbiota balance, leading to an increased risk of preterm birth. The research found a 70% change in microbiota and higher levels of pathogenic bacteria in infected women compared to control groups.
A study analyzing seroprevalence data found that global COVID-19 infection rates are likely higher than reported, with 59.2% of the population seropositive as of September 2021. The study suggests that two-thirds of the global population may have antibodies from vaccination or infection.
Researchers mapped out variations in vaccine distribution policies among 29 countries, highlighting differing priorities such as age, comorbidities, and occupation. The study suggests that vaccination schedules differ from resource allocation strategies in healthcare, reflecting diverse moral judgments underlying each approach.
A study by Children's Hospital of Philadelphia researchers found that COVID-19 vaccination results in higher antibody concentrations compared to natural infection, providing robust protection for mothers during pregnancy. The study also suggests optimal vaccine timing can maximize the transfer of antibodies to babies.
A new study found that racial resentment significantly motivates Americans to express confidence in misinformed beliefs about policy issues associated with race, such as human-caused climate change and COVID-19 origins. In contrast, this effect was not observed for less racially charged topics like childhood vaccine safety.
A study found that media literacy and trust in health experts are more powerful predictors of COVID-19 vaccine intentions than previous behavior or knowledge. Researchers also discovered that people who refused flu vaccines had lower future vaccine intentions despite higher COVID-19 knowledge.
A pre-pandemic conspiratorial mindset was associated with hesitance to accept COVID-19 vaccines, a new study suggests. Individuals who held conspiracy theories prior to the pandemic were more likely to believe in COVID-19 conspiracy theories and report hesitancy to be vaccinated.
A recent study by the Universities of Bonn and Shanxi found that Covid-19 vaccination stimulates immune response, enabling anti-PD-1 therapy to work better against nasopharyngeal cancer. Vaccinated patients responded significantly better to cancer therapy than unvaccinated counterparts.
A new study confirms that COVID-19 deaths among children and young people are rare, with most fatalities occurring in those with severe neurodisability or compromised immune systems. The analysis of detailed data showed that half of COVID-19 deaths occurred within 30 days of infection.
A study found that males younger than 40 years old who received the Moderna COVID-19 vaccine had the highest rates of myocarditis, but overall cases are rare. The study suggests that choosing specific vaccines for certain populations may maximize benefits and minimize adverse events.
A new study from Rice University found that Latino communities are hesitant to get vaccinated against COVID-19 due to concerns over side effects and mistrust of health officials. The study, which focused on communities near the U.S.-Mexico border, found that 44% of community health workers reported patients believing vaccines can have ...
Researchers found significant decline in vaccine confidence among adults since pre-pandemic surveys, regardless of age, gender, education, and ethnicity. Post-pandemic participants reported a fall in confidence in vaccines, with nearly one in four experiencing a decrease.
The study, led by C. Buddy Creech, MD, MPH, shows the vaccine is safe and generates robust immune responses in young children, providing protection against COVID-19-related hospitalization and death. The findings echo previous results, which found the vaccine to be effective in older children.
A comparative epidemiological analysis found a significant decrease in SARS-CoV-2 outbreaks and cases in German care homes following the introduction of COVID-19 vaccination. The median number of cases/outbreaks fell from 21 to 8, while the case-fatality rate decreased from 15.7% to 10.0%.
A population-level study found that COVID-19 vaccine doses 2-3 were associated with a higher relative risk but small absolute increase in glomerular disease relapse. Most flares were mild, and the benefits of vaccination outweighed the risks.
Researchers identified specific monkeypox mutations that contribute to its continued infectiousness. The virus is accumulating mutations where drugs and antibodies from vaccines are supposed to bind, making it smarter and more infectious.
A comprehensive review and meta-analysis found that young adults under 40 have a slightly elevated risk for myocarditis or pericarditis after mRNA COVID-19 vaccination. The analysis analyzed data from over 58 million participants and explored the relationship between COVID-19 vaccine and these rare but dangerous adverse reactions.
A new study led by Duke-NUS Medical School scientists found that inactivated SARS-CoV-2 vaccines elicit a broad immune response against different proteins on the virus, while mRNA vaccines stimulate a single spike protein response. This broader T-cell response may be beneficial in preventing severe COVID-19 disease.
Recent scientific studies have shed light on the effects of exposure to earlier SARS-CoV-2 forms on immune response to Omicron variants. Researchers identified a pan-variant antibody with ultra-potent neutralizing potency, which may help reduce treatment resistance.
A UCLA study found that Black Americans' mistrust of medical professionals and lower vaccination rates are linked to poor healthcare experiences, not past injustices. Researchers call for changes within the medical community to build better trust with Black patients.
The Annenberg Science and Public Health Knowledge Monitor assesses public knowledge on climate, maternal health, vaccination, and more. The quarterly survey reports aim to highlight strengths and weaknesses in public knowledge and inform public health strategies.
A multistate study found that mRNA COVID vaccines were less effective in immunocompromised adults, with protection rates ranging from 34% to 71% after multiple doses. The study emphasizes the importance of non-pharmaceutical interventions, such as masks and antibody treatment, for additional protection against severe COVID-19.
A recent study by West Virginia University sociologists found that individuals with paranormal beliefs are more likely to be hesitant about vaccination. These beliefs, which include astrology and spirits, lead to a lack of confidence in science and vaccines, including the COVID-19 shot.
A study published in The BMJ found a small increased risk of thrombosis with thrombocytopenia syndrome (TTS) after vaccination against the Covid-19 virus, particularly with adenovirus vaccines. Researchers recommend considering these risks when planning future immunization campaigns and vaccine development.
Researchers found that two-dose CoronaVac vaccination schedules, spaced 2 or 4 weeks apart, elicit similar immune responses against SARS-CoV-2 variants. The study suggests that either schedule can provide equal protection against COVID-19.
A review of COVID-19 and other adult vaccination efforts found that cash transfers and lottery programs had limited outcomes in increasing vaccination rates, with some studies showing a slight over 2% increase in coverage. Non-cash incentives also showed no significant impact on vaccination uptake.
A new study by the University of Waterloo found that individuals with anxiety disorders are not more hesitant to get vaccinated than those without. Instead, discomfort with uncertainty is a significant predictor of vaccine hesitancy in both anxious and non-anxious individuals.
Research suggests that regular physical activity enhances vaccine effectiveness against COVID-19 by improving antibody levels and mitochondrial function. High levels of physical activity were associated with higher vaccine protection rates, with significant reductions in hospital admissions and severe illness risk.
Researchers have developed an intranasal COVID-19 vaccine that works against the original virus and two variants, including omicron, in hamsters. The vaccine stimulates a strong immune response both systemically and in the respiratory tract.
A recent literature review found that vaccination against SARS-CoV-2 can effectively prevent adverse conditions such as stillbirth and infant death. Pregnant women with COVID-19 have an increased risk for stillbirth compared to uninfected women, and those who vaccinate can more effectively prevent these events.
A nationwide study found that mRNA vaccines significantly reduced the severity of Delta and Omicron COVID-19 infections in vaccinated individuals. The study, involving over 1,199 participants, also showed that breakthrough cases were more likely with Delta and Omicron variants but still limited by the vaccine's effectiveness.
A retrospective study of 26,000 patients with cirrhosis found that receiving a third dose of the COVID-19 vaccine reduced overall and severe cases by 80% and 100%, respectively. This suggests that a third dose can overcome vaccine hyporesponsiveness in patients with cirrhosis.
Researchers analyzed COVID-19 conspiracy theories on Twitter, finding that some peaked at the beginning of the pandemic while others remained persistent throughout. The study suggests that risk perceptions and lack of information from governments and experts contributed to the persistence of these theories.
The US ranks last in vaccination rates among the world's richest countries, with a mortality rate from COVID-19 30 times higher than influenza. Boosters can reduce the risk of dying and hospitalization by over 90%. All US adults and eligible children should receive booster shots to protect against future variants.
A study of 1,199 US essential and frontline workers found that recent mRNA vaccination with 2 or 3 doses before infection with Delta or Omicron variants was associated with attenuated symptoms and viral load. Vaccination status also influenced duration of illness and medical care seeking.
A survey of six European countries found strong public support for transferring COVID-19 vaccines to poorer nations and prioritizing those with the greatest need. Europeans consistently prioritized individuals most vulnerable, employed individuals, or those who lost income during the pandemic over unemployed individuals.
A study of 7,800 children under 5 years old found comparable side effects between Pfizer-BioNTech and non-COVID-19 vaccines. The results could inform vaccination recommendations for this age group.
Researchers analyzed 408 patients receiving immune checkpoint inhibitor therapy and found no increased risk of side effects from receiving both immunotherapy and the vaccine. The study supports NCCN's recommendations for COVID-19 vaccination in people with cancer, citing strong protection against severe COVID-19 for all variants.
A recent study by Penn State College of Medicine scientists found that the risk of developing myocarditis — inflammation of the heart muscle — is seven times higher with COVID-19 infection than with COVID-19 vaccination. Patients with myocarditis can experience chest pains, shortness of breath or an irregular heartbeat.
A study of Russian adults found that those who accept vaccination unconditionaly are more likely to have higher trust in government and less frequent social media use. In contrast, vaccine rejectors tend to be more extroverted and friendly but less trusting of institutions.
Researchers found that the COVID-19 vaccine can reduce the risk of SARS-CoV-2 placentitis, a condition that causes stillbirth and neonatal death. The vaccine not only protects pregnant women but may also be lifesaving for their unborn children.
The initiative vaccinated a significantly higher rate of young people, non-white populations, and Hispanic people than the average for the state and target communities. The program used a 'double equity' model to engage with local transportation companies and administered over 20,000 COVID-19 vaccination doses.
A new study shows that COVID-19 booster jabs significantly improve immunity against SARS-CoV-2 variants in elderly Singaporeans. The study found that a third vaccine dose boosts low antibody responses and T cell responses in older adults, providing better protection against severe disease.
A nationwide survey found that over 42% of Americans misrepresented their COVID-19 status and/or failed to follow public health measures. The most common reasons were a desire to feel normal and exercise personal freedom, with younger age groups and those with greater distrust of science being more likely to engage in misrepresentation.
The Omicron variant escapes the immune response better than its ancestors, but has also facilitated the transition to a society that can live with COVID-19. The study found that vaccinated individuals develop broader immune responses and experience milder infections.
A study of 265 patients found full vaccination status was associated with lower mortality among those intubated due to COVID-19-related acute respiratory distress syndrome. The results may inform discussions on prognosis for families.
Researchers recommend prioritizing COVID-19 vaccine access to older people of color and those with high-contact jobs, followed by working-age non-Hispanic whites and Asians. The study found that 'ethnic homophily' matters in vaccination strategies, leading to more deaths prevention.
Research found that pre-existing illnesses and residence in the South region were most often associated with severe outcomes in children. Vaccination was significantly protective across all age groups, with infants having more severe illness than older children. Persistent health disparities across racial and geographic lines were also...
A novel COVID-19 vaccine developed by Brazilian scientists combines two SARS-CoV-2 proteins to trigger a cellular immune response. The vaccine, called SpiN, showed promise in animal trials, protecting against three strains of the virus and reducing viral load by up to 50 times.
A large observational study in Brazil found that mRNA boosting offers considerably better protection against COVID-19 than inactivated CoronaVac boosting, particularly among elderly individuals. The findings have immediate implications for guiding boosting strategies in countries where most of the population received inactivated vaccines.