Articles tagged with Brain Injuries
A newly developed mouse trauma model reveals that the brain's protective coverings feel the brunt of even mild traumatic brain injuries. Researchers discovered a similar immune response in patients with mild head injury, suggesting a new potential treatment approach.
A study using MRI technology found that veterans with mild traumatic brain injury (MTBI) caused by blasts have long-term brain differences, including changes in white matter structure. This suggests a potential link between blast exposure and ongoing cognitive symptoms in veterans.
A study published in Neural Regeneration Research found that dl-3n-butylphthalide improved motor and sensory functions after diffuse brain injury. The compound also increased vascular density and cerebral blood flow, suggesting potential therapeutic benefits for microcirculation disorders.
Mayo Clinic researchers found that improved mood is associated with increased participation in daily activities and independent living after brain injury rehabilitation. The study suggests a holistic approach to care can address both physical and personal problems, leading to better outcomes for patients.
The UTMB project aims to develop new treatments for TBI by understanding its progressive effects and using adult circulating mesenchymal cells. Researchers hope to learn how these cells can be programmed to protect brain cells, counter inflammation or replace damaged ones.
Researchers found that a virtual sailing simulator improved quality of life, self-confidence, and overall well-being for participants with chronic spinal cord injuries. The study showed rapid improvement in sailing skills and successful completion of sailing lessons on the water.
Studies show that concussions can lead to brain abnormalities four months after symptoms have resolved, with memory and behavioral issues improving more quickly than physical injuries. These findings suggest that healing from concussions may be similar to recovering from burns, with tissue scabs forming before the body is fully healed.
Researchers have discovered a blood biomarker that accurately diagnoses concussions and predicts long-term cognitive disability. The protein SNTF levels were found to correlate with brain tissue damage, making it a potential tool for identifying patients at risk of persistent cognitive deficits.
Researchers at Tel Aviv University demonstrate hyperbaric oxygen therapy can revive brain functions and improve life quality for mild TBI patients. The treatment improved cognitive function, memory restoration, and language use, offering a new hope for millions of victims.
Researchers at MU School of Medicine found a new protocol using preventive blood thinners reduces life-threatening blood clots in brain-injured patients. The study compared outcomes between 107 and 129 patients treated with or without the medication, showing zero instances of deep-venous clotting among those who received it.
Researchers found that women injured during the premenstrual phase had slower recovery and poorer health one month after injury compared to those injured during other phases. The study suggests that sex hormones like estrogen and progesterone may play a role in concussion outcomes.
A new biosensor developed by Johns Hopkins University researchers can detect a protein associated with brain injuries, alerting doctors to devise new treatments or begin treatment more quickly. The device could help minimize brain damage and improve long-term outcomes for patients who undergo heart surgery.
A study published in Neurosurgery found significant variations in hospitals' management of children with traumatic brain injury, particularly in ICP monitoring and craniectomy. The study analyzed data from over 7,000 children treated at 156 US hospitals and found that rates of these interventions varied significantly between hospitals.
A preclinical study led by UTHealth researchers found that stem cell therapy promotes lasting cognitive improvement after brain injury. The treatment, known as MAPC therapy, was shown to reduce inflammation and improve brain function in mice.
Researchers found that amyloid beta-peptide worsened cognitive impairment following cerebral ischemia-reperfusion injury by inducing glycogen synthase kinase 3β and protein phosphatase 2A activity, resulting in tau protein phosphorylation. This study suggests a potential link between Alzheimer's disease and cerebral ischemia.
A study presented by Loyola University Medical Center sports medicine physician Neeru Jayanthi found that lower back injuries are the third most common injury suffered by young athletes under age 18. The study included over 1,200 athletes who suffered 843 injuries, with serious cases putting them at risk for long-term back problems.
A new study published in CMAJ found that the odds of patients with brain injury deteriorating to neurologic death decreased over a 10-year period, likely due to improved care and prevention measures such as road safety initiatives and enhanced clinical care.
The American Academy of Pediatrics recommends a collaborative team approach to help students recover from concussions. A gradual return to academics, with individualized adjustments as needed, is suggested to minimize disruptions and promote optimal learning and recovery.
Researchers found that Danhong injection enhances the expression of transforming growth factor-beta 1 and GM130, maintaining neuronal Golgi morphology and structure after cerebral ischemia-reperfusion injury. This study suggests a potential neuroprotective effect of Danhong injection in treating cerebral ischemia-reperfusion injury.
A recent study published by the American Academy of Pediatrics reveals that children with brain injuries are at a higher risk of developing depression. The research, which analyzed data from over 2,000 children with brain injuries, found a 4.9-fold increase in the odds of diagnosed depression compared to other children.
A study published in Journal of Neurotrauma found that genetic differences can affect an individual's recovery from traumatic brain injury. Genetic variations in cytokine genes impact the magnitude and duration of neuroinflammation, affecting long-term repair processes.
A team of researchers has developed a model system using fruit flies to study traumatic brain injury (TBI), revealing the genetic underpinnings of susceptibility and links to human TBI. The findings suggest that genetics play a crucial role in determining the outcome of an injury, which may explain why current TBI drugs have failed in ...
Approximately 1.4 million people suffer minor traumatic brain injuries (mTBI) each year, with falls and motor vehicle accidents being common causes. Orthopedic surgeons can play a critical role in diagnosing mTBI, ensuring patients receive proper care and referrals for management.
Researchers found a significant reduction in deaths among New York State patients with severe traumatic brain injury between 2001 and 2009. Adherence to the Guidelines for Management of Severe Traumatic Brain Injury increased over time, leading to improved outcomes.
Falls account for more than 60% of hospital stays for traumatic brain injury in seniors over age 65. Researchers found that hand impact occurred in 74% of falls, highlighting the need for exercises to strengthen upper limbs and design safer environments.
Researchers found that transplanted stem cells guide neural stem cells to the injured brain site via a neurovascular matrix, promoting functional recovery. The study presents evidence for a new concept of stem-cell mediated brain repair, offering a potential treatment for traumatic brain injury.
Denise Krch, PhD, of Kessler Foundation has been awarded a $600,000 NIDRR grant to develop a virtual reality program that targets executive functioning impairments in individuals with TBI. The project aims to improve problem-solving, mental flexibility, and divided attention in those with moderate to severe impairment.
A Vanderbilt study found that 74% of patients with respiratory failure, cardiogenic shock, or septic shock developed delirium in the hospital, leading to dementia-like brain disease even a year after discharge. Cognitive deficits persisted for up to 12 months in both older and younger patients.
A study published in Frontiers in Human Neuroscience found that environmental enrichment can help counteract brain atrophy in people with chronic moderate-severe traumatic brain injury (TBI). The study, led by Dr. Robin Green, suggests that increased physical, social, and cognitive stimulation can slow down brain shrinkage.
Researchers found that mild hypothermia improved behavioral scores and increased surviving neurons in rats with TBI. The treatment also reduced harmful protein levels linked to brain injury and cognitive dysfunction.
A new study published in the Journal of Neurotrauma found that low-level blast explosions can cause symptoms similar to sports concussions, including neurocognitive deficits and self-reported symptoms. The research, conducted on a group of soldiers called 'breachers', identified biomarkers capable of detecting changes in this population.
Researchers will study TSPO's role in microglia and astrocytes to understand its function in brain injury and inflammation. The goal is to discover new therapeutic targets for treating inflammation and brain injury.
A recent study found that olive leaf extract can protect against lead-induced brain injury by increasing antioxidant capacity and reducing apoptosis. The study published in Neural Regeneration Research reveals the action mechanism underlying olive leaf extract treatment for lead poisoning.
The study reveals rutaecarpine's ability to improve neurological function after cerebral ischemia reperfusion injury. The mechanism involves reducing oxidative stress, providing a promising basis for rutaecarpine as an ideal drug for preventing and treating cerebral ischemia reperfusion injury.
Children's National Hospital has received a five-year NIH grant to identify reliable early signs of prenatal brain injury in congenital heart disease. The study aims to develop non-invasive methods to detect high-risk cases before birth, opening windows for new treatments to prevent impaired brain development.
The study highlights the importance of autophagic and lysosomal activity in ischemic neurons, providing nutrition and energy for their survival. Upregulating cell autophagy or inhibiting autophagy may help eliminate abnormal components in cells after ischemic brain injury.
A review of three recent concussion guidelines highlights areas of consensus, including a definition of concussion, diagnosis, and acute care recommendations. The guidelines emphasize the importance of proper diagnosis and treatment to prevent long-term neurological consequences.
Researchers found that CTE primarily affects behavior and mood, while memory and thinking abilities are also impacted. The study suggests that athletes with CTE experience symptoms at a younger age, with mood/behavior problems appearing at an average age of 35.
A study of 36 male athletes with chronic traumatic encephalopathy (CTE) found that the disease initially affects behavior or mood and later impacts memory and thinking abilities. The researchers discovered notable differences in symptoms between those experiencing behavior problems and those with memory and thinking issues.
The University of Montana has received a $1 million grant from the US Army to further develop a drug that limits damage caused by traumatic brain injuries. The research aims to create a therapy that can be administered within hours of exposure to blast-force energy waves, potentially saving soldiers' lives.
Researchers documented irregular brain activity within hours of a concussive injury and increased brain activity weeks later, indicating the brain may compensate for the injury. The study suggests a new approach to deciding when athletes can return to play after a concussion.
A new study evaluates the accuracy of neurocognitive testing compared to self-reported symptoms of concussions in cheerleaders. Researchers found that 62% of cheerleaders reported increased symptoms after a concussion, while 33% had decreased neurocognitive performance without realizing it.
A study published in Annals of Emergency Medicine found that observing children with minor blunt head trauma in the emergency department before ordering a CT scan can significantly reduce the need for CT scans. The study found that every hour of observation time decreased CT rates by approximately 70% on average.
Researchers discover histone H1 protein's role in neurodegenerative disease and stroke; protein can trigger immune response and drive brain cell death. The study may lead to the development of new treatments for neurodegenerative diseases and stroke.
Concussions can have serious long-term health effects; therefore, it's essential to recognize and manage these injuries accurately. The article provides a 6-point protocol to help people resume activity after a concussion, emphasizing complete rest and gradual progression.
Researchers at Wake Forest Baptist Medical Center have developed a new metric called Risk Weighted Cumulative Exposure (RWE) to capture players' exposure to the risk of concussion over a football season. The study found that impact frequency was greater during games than practices, but overall exposure was greater during practices.
A study in Neurosurgery finds that most professional athletes can return to competition within a year after vertebral fusion surgery on the upper (cervical) spine. Another study analyzes variations in treatment for patients with minor head injuries seen in emergency departments versus doctors' offices.
Research published in PLOS ONE found that bodychecking rules didn't decrease concussions in elite hockey. Concussions were caused by body-checking 64% of the time, while illegal incidents accounted for only 28%. The authors suggest stricter enforcement or additional rule changes may be needed to reduce injury risk.
Research found that JNK3 expression is downregulated after traumatic brain injury, which may be associated with apoptosis of nerve cells. This downregulation could promote the recovery of neurological function following traumatic brain injury.
Researchers found that people with traumatic brain injury were 30% more likely to develop a stroke than those with trauma with no brain injury. The study looked at records of adults in California who suffered a traumatic brain injury or other trauma without brain injury over five years.
A study of 9,000 Ontario students found that 20% reported a traumatic brain injury in their lifetime, with sports accounting for over half the injuries. The prevalence is higher than previously thought and may be linked to mental health and substance use during adolescence.
A study published in JAMA found that 20.2% of adolescents in Ontario experienced traumatic brain injury, with sports injuries accounting for over half of cases. The study also identified associations between TBI and substance use, highlighting the need for improved prevention and response strategies among adolescents.
A study found that 20% of adolescents in Ontario reported having suffered a traumatic brain injury, with males and those with lower grades more likely to experience injuries during sports. The prevalence of TBI among young people is much higher than previously thought.
Researchers found that a combination of two proteins, S100B and apoA-1, helps most accurately classify head injuries. This study provides significant evidence for the potential use of blood tests in diagnosing mild traumatic brain injury.
Researchers found a striking resemblance between white matter brain abnormalities in concussion patients and those seen in early Alzheimer's dementia. The study suggests that the true problem facing concussion patients may be their brain's response to injury, rather than the injury itself.
A study published in Traffic Injury Prevention found that bicycle helmets certified to Australia's national standard significantly reduce linear and angular head accelerations and impact force. Helmet use greatly reduces the risk of head, skull and brain injury by up to 9.5 times.
A study published in Radiology found that frequent heading in soccer is associated with white matter microstructural changes and cognitive impairments, similar to those seen in traumatic brain injury patients. Players who headed the ball over 1,800 times per year showed poorer memory scores.
Researchers found white-matter abnormalities in soccer players who headed the ball over 885-1,550 times a year, associated with cognitive impairment. Players with more than 1,800 headings per year showed poorer memory scores, suggesting frequent heading may cause brain injury.
Scientists at Kessler Foundation received grants to investigate emotional processing deficits in individuals with traumatic brain injury (TBI) and the effects of aerobic exercise on memory impairments. The studies aim to develop innovative rehabilitation interventions using objective data from brain imaging.
A new study finds that bright light therapy can improve sleep quality, reduce daytime sleepiness, and alleviate depressive symptoms in individuals with mild traumatic brain injury (TBI). The treatment also shows changes in brain activation during cognitive tasks, suggesting potential improvements in brain function.