Articles tagged with Brain Injuries
A new study confirms a variant in the SERPINE1 gene is linked to cerebral palsy and death in very preterm babies. The findings add to evidence that genes may play a role in brain injury and death risk in preterm infants.
Researchers found that retrieval practice (RP) significantly improved memory in individuals with severe traumatic brain injury (TBI), particularly after short delays. RP was more effective than massed restudy (MR) or spaced restudy (SR) strategies, indicating its potential to improve real-life performance.
A Johns Hopkins study finds that newborn brain injury causes different responses in male and female brains, with females showing milder cell death and better response to certain therapies. Researchers highlight the need for gender-specific research to develop precisely targeted treatments.
Researchers Sarj Patel and Tom Rau aim to identify biomarkers of TBI through blood samples, improving diagnosis and treatment. The goal is to understand how localized injuries affect the entire brain.
Researchers at IU School of Medicine will use advanced neuroimaging techniques to study high school athletes and understand the impact of concussions on brain blood flow. The study aims to improve understanding of concussion symptoms, cognitive functioning, and detection methods.
A new study found that an estimated 530,494 children were injured in US emergency departments from 1990 to 2011 due to shopping cart-related incidents. The majority of injuries were head trauma cases, with a significant increase in concussions and closed-head injuries over the study period.
A new study found that NHL teams pay out $218 million annually for lost time due to injuries. Concussions were the most expensive type of injury, accounting for $42.8 million per year. The research highlights the need for better protection for athletes in hockey.
Concussions are common among middle-school girls who play soccer, with cumulative concussion incidence of 13 percent per season. Most players (58.6%) continue to play with symptoms, while almost half (44.1%) seek medical attention.
Researchers discovered that brain regions synchronize their activity to make it possible for people to pay attention, with the process likened to tuning multiple walkie-talkies to the same frequency. The findings have implications for understanding attention deficits in brain injuries or strokes.
Researchers found that traumatic brain injury (TBI) survivors are three times more likely to die prematurely from suicide or fatal injuries. The study also showed that TBI survivors who have a history of substance abuse or psychiatric disorders are at highest risk of premature death.
Researchers have discovered a novel method of treating traumatic brain injury by stimulating 'caretaker cells' to reduce swelling. The treatment, using compounds like 2-methylthio-ADP and MRS2365, has shown promise in reducing edema and prolonging the life of neurons.
The US Army's new strategic research plan aims to improve treatment outcomes for traumatic brain injury by identifying critical research priority areas. The report highlights six main target areas, including pharmacological interventions and preclinical drug assessment.
Researchers used mass spectrometry to identify 10 differentially expressed proteins in the brain after acute high-altitude hypoxia. These proteins are involved in the electron transport chain and ATP synthase function, providing potential targets for treating hypobaric hypoxia-related brain injury.
Researchers found that fetal umbilical veins exhibit stress relaxation and creep properties similar to those of middle cerebral arteries, making them a suitable alternative for reconstruction. These findings indicate that the fetal umbilical vein can be transplanted to repair middle cerebral artery injury with favorable outcomes.
Scientists use reactive glial cells to regenerate healthy neurons in a breakthrough technology for treating brain injuries and Alzheimer's disease. In mouse models and human cell cultures, the method successfully converts glial cells into functional neurons.
A new review published in the journal Neuropsychology Review finds that computerized neurocognitive testing for concussions lacks consistent evidence on reliability and validity. The study suggests caution when using these tests due to their marketing prevalence over scientific proof, emphasizing the need for a multi-dimensional approa...
The NIH has selected eight projects to study the long-term effects of repeated head injuries and develop more accurate concussion diagnoses. The partnership between the NIH and the NFL aims to reduce the risk of chronic traumatic encephalopathy (CTE) in athletes and military personnel.
The grant aims to build a more precise understanding of chronic traumatic encephalopathy and traumatic brain injury in civilians over age 45. Investigators will use extensive resources from an ongoing study of brain aging and conduct analyses of neuropsychology, neuroradiology, neurological, geriatric, and epidemiological aspects.
A study of U.S. Marines found that traumatic brain injury (TBI) during deployment was a significant predictor of post-traumatic stress disorder (PTSD) over time. Pre-deployment PTSD symptoms and combat intensity also played a role in the development of PTSD.
Researchers found that feeding mice with branched chain amino acids improved sleep disturbances and restored orexin neurons to normal activity levels, suggesting a dietary treatment for TBI patients. The study provides a proof-of-principle for investigating this intervention as a potential public health benefit.
Researchers at Stanford University have observed a cellular response to concussions in mice, revealing how individual cells react to the injury. The study suggests a possible therapeutic approach by using natural antioxidant molecules like glutathione to prevent brain damage.
Scientists have successfully restored behavior in rats using a neural prosthesis after brain injury. The device, a closed-loop microelectronic system, recorded signals from one part of the brain and stimulated another to facilitate repair. Two weeks after implantation, rat models recovered nearly all function lost due to injury.
A new study suggests that a head injury can lead to depressive complications years later due to an overactive immune response and inflammation. The research found that brain cells went on 'high alert' after the injury, affecting behavior and leading to symptoms that were linked to inflammation.
A study by Nationwide Children's Hospital found nearly all high chair-related injuries involve a fall, with 93% of cases reporting a child climbing or standing in the chair. The annual number of injured children increased by almost 90%, with closed head injuries and facial injuries being most common.
A newly developed mouse trauma model reveals that the brain's protective coverings feel the brunt of even mild traumatic brain injuries. Researchers discovered a similar immune response in patients with mild head injury, suggesting a new potential treatment approach.
A study using MRI technology found that veterans with mild traumatic brain injury (MTBI) caused by blasts have long-term brain differences, including changes in white matter structure. This suggests a potential link between blast exposure and ongoing cognitive symptoms in veterans.
A study published in Neural Regeneration Research found that dl-3n-butylphthalide improved motor and sensory functions after diffuse brain injury. The compound also increased vascular density and cerebral blood flow, suggesting potential therapeutic benefits for microcirculation disorders.
Mayo Clinic researchers found that improved mood is associated with increased participation in daily activities and independent living after brain injury rehabilitation. The study suggests a holistic approach to care can address both physical and personal problems, leading to better outcomes for patients.
The UTMB project aims to develop new treatments for TBI by understanding its progressive effects and using adult circulating mesenchymal cells. Researchers hope to learn how these cells can be programmed to protect brain cells, counter inflammation or replace damaged ones.
Studies show that concussions can lead to brain abnormalities four months after symptoms have resolved, with memory and behavioral issues improving more quickly than physical injuries. These findings suggest that healing from concussions may be similar to recovering from burns, with tissue scabs forming before the body is fully healed.
Researchers found that a virtual sailing simulator improved quality of life, self-confidence, and overall well-being for participants with chronic spinal cord injuries. The study showed rapid improvement in sailing skills and successful completion of sailing lessons on the water.
Researchers have discovered a blood biomarker that accurately diagnoses concussions and predicts long-term cognitive disability. The protein SNTF levels were found to correlate with brain tissue damage, making it a potential tool for identifying patients at risk of persistent cognitive deficits.
Researchers at MU School of Medicine found a new protocol using preventive blood thinners reduces life-threatening blood clots in brain-injured patients. The study compared outcomes between 107 and 129 patients treated with or without the medication, showing zero instances of deep-venous clotting among those who received it.
Researchers at Tel Aviv University demonstrate hyperbaric oxygen therapy can revive brain functions and improve life quality for mild TBI patients. The treatment improved cognitive function, memory restoration, and language use, offering a new hope for millions of victims.
Researchers found that women injured during the premenstrual phase had slower recovery and poorer health one month after injury compared to those injured during other phases. The study suggests that sex hormones like estrogen and progesterone may play a role in concussion outcomes.
A study published in Neurosurgery found significant variations in hospitals' management of children with traumatic brain injury, particularly in ICP monitoring and craniectomy. The study analyzed data from over 7,000 children treated at 156 US hospitals and found that rates of these interventions varied significantly between hospitals.
A new biosensor developed by Johns Hopkins University researchers can detect a protein associated with brain injuries, alerting doctors to devise new treatments or begin treatment more quickly. The device could help minimize brain damage and improve long-term outcomes for patients who undergo heart surgery.
A preclinical study led by UTHealth researchers found that stem cell therapy promotes lasting cognitive improvement after brain injury. The treatment, known as MAPC therapy, was shown to reduce inflammation and improve brain function in mice.
Researchers found that amyloid beta-peptide worsened cognitive impairment following cerebral ischemia-reperfusion injury by inducing glycogen synthase kinase 3β and protein phosphatase 2A activity, resulting in tau protein phosphorylation. This study suggests a potential link between Alzheimer's disease and cerebral ischemia.
A new study published in CMAJ found that the odds of patients with brain injury deteriorating to neurologic death decreased over a 10-year period, likely due to improved care and prevention measures such as road safety initiatives and enhanced clinical care.
A study presented by Loyola University Medical Center sports medicine physician Neeru Jayanthi found that lower back injuries are the third most common injury suffered by young athletes under age 18. The study included over 1,200 athletes who suffered 843 injuries, with serious cases putting them at risk for long-term back problems.
Researchers found that Danhong injection enhances the expression of transforming growth factor-beta 1 and GM130, maintaining neuronal Golgi morphology and structure after cerebral ischemia-reperfusion injury. This study suggests a potential neuroprotective effect of Danhong injection in treating cerebral ischemia-reperfusion injury.
The American Academy of Pediatrics recommends a collaborative team approach to help students recover from concussions. A gradual return to academics, with individualized adjustments as needed, is suggested to minimize disruptions and promote optimal learning and recovery.
A recent study published by the American Academy of Pediatrics reveals that children with brain injuries are at a higher risk of developing depression. The research, which analyzed data from over 2,000 children with brain injuries, found a 4.9-fold increase in the odds of diagnosed depression compared to other children.
A study published in Journal of Neurotrauma found that genetic differences can affect an individual's recovery from traumatic brain injury. Genetic variations in cytokine genes impact the magnitude and duration of neuroinflammation, affecting long-term repair processes.
A team of researchers has developed a model system using fruit flies to study traumatic brain injury (TBI), revealing the genetic underpinnings of susceptibility and links to human TBI. The findings suggest that genetics play a crucial role in determining the outcome of an injury, which may explain why current TBI drugs have failed in ...
Approximately 1.4 million people suffer minor traumatic brain injuries (mTBI) each year, with falls and motor vehicle accidents being common causes. Orthopedic surgeons can play a critical role in diagnosing mTBI, ensuring patients receive proper care and referrals for management.
Researchers found a significant reduction in deaths among New York State patients with severe traumatic brain injury between 2001 and 2009. Adherence to the Guidelines for Management of Severe Traumatic Brain Injury increased over time, leading to improved outcomes.
Falls account for more than 60% of hospital stays for traumatic brain injury in seniors over age 65. Researchers found that hand impact occurred in 74% of falls, highlighting the need for exercises to strengthen upper limbs and design safer environments.
Researchers found that transplanted stem cells guide neural stem cells to the injured brain site via a neurovascular matrix, promoting functional recovery. The study presents evidence for a new concept of stem-cell mediated brain repair, offering a potential treatment for traumatic brain injury.
Denise Krch, PhD, of Kessler Foundation has been awarded a $600,000 NIDRR grant to develop a virtual reality program that targets executive functioning impairments in individuals with TBI. The project aims to improve problem-solving, mental flexibility, and divided attention in those with moderate to severe impairment.
A Vanderbilt study found that 74% of patients with respiratory failure, cardiogenic shock, or septic shock developed delirium in the hospital, leading to dementia-like brain disease even a year after discharge. Cognitive deficits persisted for up to 12 months in both older and younger patients.
A study published in Frontiers in Human Neuroscience found that environmental enrichment can help counteract brain atrophy in people with chronic moderate-severe traumatic brain injury (TBI). The study, led by Dr. Robin Green, suggests that increased physical, social, and cognitive stimulation can slow down brain shrinkage.
Researchers found that mild hypothermia improved behavioral scores and increased surviving neurons in rats with TBI. The treatment also reduced harmful protein levels linked to brain injury and cognitive dysfunction.
Researchers will study TSPO's role in microglia and astrocytes to understand its function in brain injury and inflammation. The goal is to discover new therapeutic targets for treating inflammation and brain injury.
A new study published in the Journal of Neurotrauma found that low-level blast explosions can cause symptoms similar to sports concussions, including neurocognitive deficits and self-reported symptoms. The research, conducted on a group of soldiers called 'breachers', identified biomarkers capable of detecting changes in this population.
A recent study found that olive leaf extract can protect against lead-induced brain injury by increasing antioxidant capacity and reducing apoptosis. The study published in Neural Regeneration Research reveals the action mechanism underlying olive leaf extract treatment for lead poisoning.
The study reveals rutaecarpine's ability to improve neurological function after cerebral ischemia reperfusion injury. The mechanism involves reducing oxidative stress, providing a promising basis for rutaecarpine as an ideal drug for preventing and treating cerebral ischemia reperfusion injury.
The study highlights the importance of autophagic and lysosomal activity in ischemic neurons, providing nutrition and energy for their survival. Upregulating cell autophagy or inhibiting autophagy may help eliminate abnormal components in cells after ischemic brain injury.
Children's National Hospital has received a five-year NIH grant to identify reliable early signs of prenatal brain injury in congenital heart disease. The study aims to develop non-invasive methods to detect high-risk cases before birth, opening windows for new treatments to prevent impaired brain development.